Gene_locus Report for: corgb-a4qhw6 Corynebacterium glutamicum (strain R) Putative uncharacterized protein
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Corynebacteriales: N E > Corynebacteriaceae: N E > Corynebacterium: N E > Corynebacterium glutamicum: N E
6_AlphaBeta_hydrolase :
corgl-CGL0091 Corynebacterium glutamicum (Brevibacterium flavum) superfamily) (EC 3.3.2.3) ,
corgl-CGL1144 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) Predicted hydrolases or acyltransferases Alpha/beta hydrolase superfamily ,
corgl-CGL2067 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) hypothetical protein cgl2067 ,
corgl-CGL2254 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) predicted hydrolase or acyltransferase ,
corgl-CGL2568 Corynebacterium glutamicum (Brevibacterium flavum) hypothetical protein cgl2568 ,
corgl-q5krb4 Corynebacterium glutamicum (Brevibacterium flavum) hypothetical protein .
A85-Est-Putative :
corgl-y967 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) hypothetical protein cgl0967 (orf2) .
A85-IroE-IroD-Fes-Yiel :
corgl-CGL2474 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) putative enterochelin esterase cgl2474 .
A85-Mycolyl-transferase :
corgb-a4qhr7 Corynebacterium glutamicum (strain R) Putative uncharacterized protein ,
corgl-CGL0343 Corynebacterium glutamicum (Brevibacterium flavum), hypothetical protein cgl0343,
corgl-CGL0922 Corynebacterium glutamicum (Brevibacterium flavum) hypothetical protein cgl0922 ,
corgl-CGL1031 Corynebacterium glutamicum (Brevibacterium flavum) (and ATCC 13032; R) hypothetical protein cgl1031 ,
corgl-CGL2181 Corynebacterium glutamicum (Brevibacterium flavum) (and strains ATCC 13032; R) hypothetical protein cgl2181 ,
corgl-CGL2878 Corynebacterium glutamicum (Brevibacterium flavum) (and strains ATCC 13032; R) predicted esterase ,
corgl-CMT3 Corynebacterium glutamicum (Brevibacterium flavum) corynomycolyl transferase (EC 2.3.1.122) cmt3 ,
corgl-csp1 Corynebacterium glutamicum (Brevibacterium flavum); Corynebacterium melassecola mycoloyltransferase ps1 protein precursor CSP1 COP1 MytA NCgl2777 CGL2875.
Abhydrolase_9 :
corgl-q8nlm9 Corynebacterium glutamicum (Brevibacterium flavum); Corynebacterium [Brevibacterium] flavum; Corynebacterium crenatum Putative uncharacterized protein Cgl2912 ,
corgt-a0a169s8h1 Corynebacterium glutamicum (Brevibacterium saccharolyticum) Uncharacterized protein .
AlphaBeta_hydrolase :
corgl-CGL2618 Corynebacterium glutamicum (Brevibacterium flavum) hypothetical protein cgl2618 .
Carboxymethylbutenolide_lactonase :
corgl-CGL2393 Corynebacterium glutamicum (Brevibacterium flavum) Putative uncharacterized protein (EC 3.1.1.24) .
Carb_B_Bacteria :
corgl-Cgl1133 Corynebacterium glutamicum (Brevibacterium saccharolyticum), Corynebacterium crenatum, lipT gene type b carboxylesterase (EC 3.1.1.1) ,
corgl-Cgl2249 Corynebacterium glutamicum (Brevibacterium saccharolyticum), Corynebacterium crenatum, esterase Cgl2249 gene ,
corgt-a0a160pr30 Corynebacterium glutamicum (Brevibacterium saccharolyticum). Carboxylic ester hydrolase ,
corgt-a0a160prc4 Corynebacterium glutamicum (Brevibacterium saccharolyticum). Carboxylic ester hydrolase .
Chlorophyllase :
corgl-CGL0587 Corynebacterium glutamicum (Brevibacterium flavum) hypothetical protein cgl0587 .
Cutinase :
corgl-q8nlr5 Corynebacterium glutamicum (Brevibacterium flavum) hypothetical protein cgl2873 (putative secreted protein) .
Duf_1023 :
corgl-q8nlz1 Corynebacterium glutamicum (Brevibacterium flavum) (Brevibacterium saccharolyticum), Corynebacterium crenatum, hypothetical protein cgl2795 ,
corgt-a0a161jp85 Corynebacterium glutamicum, Uncharacterized protein .
Epoxide_hydrolase :
corgl-ephli Corynebacterium glutamicum (and strain R) Sequence 225 Patent WO0100842 ephli .
Est-OsmC :
corgl-CGL1439 Corynebacterium glutamicum (Brevibacterium flavum) esterase is found in n-term of an OsmC/Ohr family domain .
Fungal-Bact_LIP :
corgl-CGL1481 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) hypothetical protein cgl1481 (EC 3.1.1.3) .
Homoserine_transacetylase :
corgl-metx Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) (homoserine transacetylase) (hta) .
Homoserine_transacetylase_like_est :
corgl-CGL0839 Corynebacterium glutamicum (Brevibacterium flavum)CgHle CGL0839 homoserine acetyltransferase like esterase.
Hormone-sensitive_lipase_like :
corgl-CGL0118 Corynebacterium glutamicum (Brevibacterium flavum) esterase/lipase ,
corgl-CGL0151 Corynebacterium glutamicum (Brevibacterium flavum) hypothetical protein cgl0151 .
Lipase_2 :
corgl-199 Corynebacterium glutamicum Q8NU60 Sequence 199 (and strain R) Patent WO0100805 lipase ,
corgl-CGL0081 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) hydrolase fold (EC 3.1.1.3) .
Monoglyceridelipase_lysophospholip :
corgl-CGL2002 Corynebacterium glutamicum (Brevibacterium flavum), Corynebacterium glutamicum, hypothetical protein cgl2002 .
Proline_iminopeptidase :
corgl-CGL0591 Corynebacterium glutamicum (Brevibacterium flavum) prolyl aminopeptidase a (EC 3.4.11.5) .
S9N_PPCE_Peptidase_S9 :
corgl-CGL0340 Corynebacterium glutamicum (Brevibacterium flavum) serine proteases of the peptidase family s9a (EC 3.4.21.26) .
S9N_PREPL_Peptidase_S9 :
corgl-CGL2596 Corynebacterium glutamicum (Brevibacterium flavum) protease II .
Thioesterase :
corgl-CGL2871 Corynebacterium glutamicum polyketide synthase modules thioesterase from aa 1350 to 1610 .
Tiancimycin-TnmK-Tripeptidase-HIP :
corgl-CGL1178 Corynebacterium glutamicum (Brevibacterium flavum) AlphaBeta_hydrolase superfamily) .
UCP037442 :
corgl-CGL0007 Corynebacterium glutamicum (Brevibacterium flavum) (and strain R) hypothetical protein cgl0007
Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: corgb-a4qhw6 Colored MSA for Abhydrolase_9 (raw)
MVSLPRLASLLTTRLATLKPALKPATHLASLGAQVIAELVPGIRMSPNRR
RILPANMGAGFIGAEIAMWWALSPSLLPKPWWVTAANLAVLQAVGHAAAT
GIHSILPRTNRRVSRKIYNATHIATGAITLTTTVVGLIRHRTQIRLIGQK
NFGPKETIAGISVGTLGYGALLITGELTQHSINEVKRLIERFLPPWISFI
AAVSVITLTTVTLTDRVLLRRILHNSAIQAAHLNRMVFPGTEQPWEPERS
GSPWSYEKWGAVGSQGRAVLSGGPRKDDIITVTRLSDTETHEPIRIFIGM
VPGRSLSDQVDLVIHEMRRTGALRRDHIVINNSTGTGWITDWSAHTFEFL
TGGNCVTISMQYSYLPSALSWYKDNDGPINAARMLIDAVLHELDQLPTGS
RPKLFLAGESLGAYGLAEVWGDVEKLLGTADGVLFSGAPRFSDAMNALRT
RRDASSSERLPVIDSGRHIRFAGEPEHLDMPATWQFPRMIVAQHASDPIV
WWNAELFIRRPEWLKTPQQDHQDVFPRLRWMPFVTGWQVALDLLTSTSAP
GGHGHNYHEEFIDYWAALLDREVTPELRHSIAYWIRANHIKR
Legend
This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA
M V S L P R L A S L L T T R L A T L K P A L K P A T H L A S L G A Q V I A E L V P G I R M S P N R R R I L P A N M G A G F I G A E I A M W W A L S P S L L P K P W W V T A A N L A V L Q A V G H A A A T G I H S I L P R T N R R V S R K I Y N A T H I A T G A I T L T T T V V G L I R H R T Q I R L I G Q K N F G P K E T I A G I S V G T L G Y G A L L I T G E L T Q H S I N E V K R L I E R F L P P W I S F I A A V S V I T L T T V T L T D R V L L R R I L H N S A I Q A A H L N R M V F P G T E Q P W E P E R S G S P W S Y E K W G A V G S Q G R A V L S G G P R K D D I I T V T R L S D T E T H E P I R I F I G M V P G R S L S D Q V D L V I H E M R R T G A L R R D H I V I N N S T G T G W I T D W S A H T F E F L T G G N C V T I S M Q Y S Y L P S A L S W Y K D N D G P I N A A R M L I D A V L H E L D Q L P T G S R P K L F L A G E S L G A Y G L A E V W G D V E K L L G T A D G V L F S G A P R F S D A M N A L R T R R D A S S S E R L P V I D S G R H I R F A G E P E H L D M P A T W Q F P R M I V A Q H A S D P I V W W N A E L F I R R P E W L K T P Q Q D H Q D V F P R L R W M P F V T G W Q V A L D L L T S T S A P G G H G H N Y H E E F I D Y W A A L L D R E V T P E L R H S I A Y W I R A N H I K R
Reference
Title: Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R
Yukawa H , Omumasaba CA , Nonaka H , Kos P , Okai N , Suzuki N , Suda M , Tsuge Y , Watanabe J and Inui M <2 more author(s)>
Yukawa H , Omumasaba CA , Nonaka H , Kos P , Okai N , Suzuki N , Suda M , Tsuge Y , Watanabe J , Ikeda Y , Vertes AA , Inui M (- 2)
Ref: Microbiology, 153 :1042, 2007 : PubMed Abstract ESTHER: Yukawa_2007_Microbiology_153_1042 PubMedSearch: Yukawa 2007 Microbiology 153 1042 PubMedID: 17379713 Gene_locus related to this paper: corgb-a4qhr7 ,
corgb-a4qhw6 ,
corgl-199 ,
corgl-CGL0007 ,
corgl-CGL0081 ,
corgl-CGL0340 ,
corgl-CGL0343 ,
corgl-CGL0591 ,
corgl-CGL1031 ,
corgl-Cgl1133 ,
corgl-CGL1144 ,
corgl-CGL1481 ,
corgl-CGL2002 ,
corgl-CGL2067 ,
corgl-CGL2181 ,
corgl-Cgl2249 ,
corgl-CGL2254 ,
corgl-CGL2393 ,
corgl-CGL2474 ,
corgl-CGL2878 ,
corgl-ephli ,
corgl-metx ,
corgl-q8nlr5 ,
corgl-q8nlz1 ,
corgl-y967 ,
corgt-g6wsn6 Abstract
The complete genome sequence of Corynebacterium glutamicum strain R was determined to allow its comparative analysis with other corynebacteria. The biology of corynebacteria was explored by refining the definition of the subset of genes that constitutes the corynebacterial core as well as those characteristic of saprophytic and pathogenic ecological niches. In addition, the relative scarcity of corynebacterial sigma factors and the plasticity of their two-component system machinery reflect their relatively exacting nutritional requirements and reduced membrane-associated and secreted proteins. The conservation of key genes and pathways between corynebacteria, mycobacteria and Nocardia validates the use of C. glutamicum to study fundamental processes that are conserved in slow-growing mycobacteria, including pathogenesis-associated mechanisms. The discovery of 39 novel genes in C. glutamicum R that have not been previously reported in other corynebacteria supports the rationale for sequencing additional corynebacterial genomes to better define the corynebacterial pan-genome and identify previously undetected metabolic pathways in these organisms.
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