Gene_Locus Report
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Gene_locus Report for: culqu-2estb

Culex quinquefasciatus (Southern house mosquito) serine esterase B

Comment
Other strains; Culex quinquefasciatus (MRes) (Southern house mosquito), Culex pipiens complex sp. MW-2012


Relationship
Family|Carb_B_Arthropoda
Block| C
Position in NCBI Life Tree|Culex quinquefasciatus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Nematocera: N E > Culicomorpha: N E > Culicoidea: N E > Culicidae: N E > Culicinae: N E > Culicini: N E > Culex [genus]: N E > Culex [subgenus]: N E > Culex pipiens complex: N E > Culex quinquefasciatus: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 2 more: Z32695, EF471907, JQ341054
>3 UniProt links 1 more: A4URM1, V9IQG6, V9IQK4
1 Ncbi-nid : 475069
>3 UniProt links 2 more: Q23735, A4URM1, V9IQG6
>3 Interpro links 2 more: Q23735, A4URM1, V9IQG6
>3 Pfam links 2 more: Q23735, A4URM1, V9IQG6
>3 PIRSF links 2 more: Q23735, A4URM1, V9IQG6
>3 SUPERFAM links 2 more: Q23735, A4URM1, V9IQG6
Sequence
Peptide
Graphical view for this peptide sequence: culqu-2estb
Colored MSA for Carb_B_Arthropoda (raw) 
MSLESLTVQTKYGPVRGKRSVSLLGQEYVSFQGIPYARAPEGELRFKAPV
PPQNWTETLDCTQQCEPCYHFDRRLQKIVGCEDSLKINVFAKEINPSKPL
PVMLYIYGGGFTEGTSGTELYGPDFLVQKDIVLVSFNYRIGALGFLCCQS
EQDGVPGNAGLKDQNLAIWWVLENIGAFGGDPKRVTLVGHSAGAASVQYH
LISDASKDLFQRAIVMSGSTYNSWSLTRQRNWVEKLAKAIGWDGQGGESG
ALRFLRAAKPEDIVANQEKLLTDQDMQDDIFTPFGPTVEPYLTEQCMIPK
EPFEMARTAWGDKIDIMIGGTSEEGLLLLQKIKLQPELLSHPHLFLGNVP
PNLKISMEKRIEFAAKLKQRYYPDSSPSMENNLGYVHMMSDRVFWHGLHR
TILARAARSRARTFVYRICLDSEFYNHYRIMMIDPKLRGTAHADELSYLF
SKFTQQVPDKKTFEYRGLQTLVDVFTAFVINGDPNCSMTAKSGVVFEPNS
QTKPTFKCLNIANDGLALVDYPDADRLDMWDAMYVNDELF
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA
MSLESLTVQTKYGPVRGKRSVSLLGQEYVSFQGIPYARAPEGELRFKAPV
PPQNWTETLDCTQQCEPCYHFDRRLQKIVGCEDSLKINVFAKEINPSKPL
PVMLYIYGGGFTEGTSGTELYGPDFLVQKDIVLVSFNYRIGALGFLCCQS
EQDGVPGNAGLKDQNLAIWWVLENIGAFGGDPKRVTLVGHSAGAASVQYH
LISDASKDLFQRAIVMSGSTYNSWSLTRQRNWVEKLAKAIGWDGQGGESG
ALRFLRAAKPEDIVANQEKLLTDQDMQDDIFTPFGPTVEPYLTEQCMIPK
EPFEMARTAWGDKIDIMIGGTSEEGLLLLQKIKLQPELLSHPHLFLGNVP
PNLKISMEKRIEFAAKLKQRYYPDSSPSMENNLGYVHMMSDRVFWHGLHR
TILARAARSRARTFVYRICLDSEFYNHYRIMMIDPKLRGTAHADELSYLF
SKFTQQVPDKKTFEYRGLQTLVDVFTAFVINGDPNCSMTAKSGVVFEPNS
QTKPTFKCLNIANDGLALVDYPDADRLDMWDAMYVNDELF

References
    Title: Identification and characterization of novel organophosphate detoxifying esterase alleles in the Guangzhou area of China
    Weill M, Marquine M, Berthomieu A, Dubois MP, Bernard C, Qiao CL, Raymond M
    Ref: J Am Mosq Control Assoc, 17:238, 2001 : PubMed

            

    Title: The independent gene amplification of electrophoretically indistinguishable B esterases from the insecticide-resistant mosquito Culex quinquefasciatus
    Vaughan A, Rodriguez M, Hemingway J
    Ref: Biochemical Journal, 305 ( Pt 2):651, 1995 : PubMed

            


Other Papers

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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