danre-nlgn4a

 
Danio rerio (Zebrafish) (Brachydanio rerio) Neuroligin 4a

Relationship
Family Neuroligin
Block C
Danio rerio position in NCBI Life Tree :
N link to NCBI taxonomic web page and E link to ESTHER gene locus found in this strain.
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Actinopterygii: N E > Actinopteri: N E > Neopterygii: N E > Teleostei: N E > Osteoglossocephalai: N E > Clupeocephala: N E > Otomorpha: N E > Ostariophysi: N E > Otophysi: N E > Cypriniphysae: N E > Cypriniformes: N E > Cyprinoidea: N E > Cyprinidae: N E > Danio: N E > Danio rerio: N E

Molecular evidence
Database
No mutation
No structure
No kinetic



>3 Genbank links 2 more: GQ489195, GQ892839, CU462859
>3 UniProt links 2 more: D2X2G4, D0EVX4, F1Q7W8
>3 UniProtTrembl links 2 more: D2X2G4, D0EVX4, F1Q7W8
>3 Interpro links 2 more: D2X2G4, D0EVX4, F1Q7W8
>3 Prodom links 2 more: D2X2G4, D0EVX4, F1Q7W8
>3 Pfam links 2 more: D2X2G4, D0EVX4, F1Q7W8
>3 PIRSF links 2 more: D2X2G4, D0EVX4, F1Q7W8
>3 SUPERFAM links 2 more: D2X2G4, D0EVX4, F1Q7W8
>3 QuickSwissBlast links 2 more: D2X2G4, D0EVX4, F1Q7W8
 
Sequence
Graphical view for this peptide sequence: danre-nlgn4a
Colored MSA for Neuroligin (raw)
MSRLKGTPWIPLTVVHPLATLRLFTWIVLAAAWLAITWAQQHPIVTTNYG
KLRGLKTPLPNEILGPVEQYLGIPYALPPTGERRFQPPEPPMSWPGIRNA
TQFAPVCPQFLEDRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYV
PTEDGANKGDDFTNNEGGENKDIHDENGLRPVMVYIHGGSYMEGTGNMID
GSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIKE
NIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSS
WAVNYQPAKYTRILAEKVGCNMLDSIDLVECLQNKNYKELIEQYITQAKY
HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGFKFVDGIVDS
EDGVSANDFDFAVSDFVDHLYGYPEGKDTLRETIKFMYTDWADKENPETR
RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWSD
SAHGDEVPYVFGIPMLGPTDLFNCNFSKNDVMLSAVVMTYWTNFAKTGDP
NQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATK
VAFWLELVPHLHNINELFQYVSTTTKIPPQDTTPFPYTKRLGKTWPSTTR
HPGVPPANTKQTTDQRKGNDLSDDSAVVIETKRDYSTELSVTIAVGASLL
FLNILAFAALYYKKDKRRHESNRRGPSPQRNSAPANVVANANDIAHLQSD
ELMSLQMKQQQMEHEHHHECDSLQAHDTLRLTCPADYTLTLRRSPDDIPL
MTPSTITMIPNTLAGMQTLHNFNTFGGSQNSTNLPHGHSTTRV
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MSRLKGTPWIPLTVVHPLATLRLFTWIVLAAAWLAITWAQQHPIVTTNYG
KLRGLKTPLPNEILGPVEQYLGIPYALPPTGERRFQPPEPPMSWPGIRNA
TQFAPVCPQFLEDRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYV
PTEDGANKGDDFTNNEGGENKDIHDENGLRPVMVYIHGGSYMEGTGNMID
GSILASYGNVIVVTLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIKE
NIQAFKGDPKRVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIQSGTALSS
WAVNYQPAKYTRILAEKVGCNMLDSIDLVECLQNKNYKELIEQYITQAKY
HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGFKFVDGIVDS
EDGVSANDFDFAVSDFVDHLYGYPEGKDTLRETIKFMYTDWADKENPETR
RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWSD
SAHGDEVPYVFGIPMLGPTDLFNCNFSKNDVMLSAVVMTYWTNFAKTGDP
NQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATK
VAFWLELVPHLHNINELFQYVSTTTKIPPQDTTPFPYTKRLGKTWPSTTR
HPGVPPANTKQTTDQRKGNDLSDDSAVVIETKRDYSTELSVTIAVGASLL
FLNILAFAALYYKKDKRRHESNRRGPSPQRNSAPANVVANANDIAHLQSD
ELMSLQMKQQQMEHEHHHECDSLQAHDTLRLTCPADYTLTLRRSPDDIPL
MTPSTITMIPNTLAGMQTLHNFNTFGGSQNSTNLPHGHSTTRV

no DNA




References
    Title: The zebrafish reference genome sequence and its relationship to the human genome
    Howe K, Clark MD, Torroja CF, Torrance J, Berthelot C, Muffato M, Collins JE, Humphray S, McLaren K and Stemple DL <167 more author(s)>
    Ref: Nature, 496:498, 2013 : PubMed

            

    Title: Differential expression of neuroligin genes in the nervous system of zebrafish
    Davey C, Tallafuss A, Washbourne P
    Ref: Developmental Dynamics, 239:703, 2010 : PubMed

            

    Title: Characterization of the neuroligin gene family expression and evolution in zebrafish
    Rissone A, Sangiorgio L, Monopoli M, Beltrame M, Zucchi I, Bussolino F, Arese M, Cotelli F
    Ref: Developmental Dynamics, 239:688, 2010 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
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