Gene_Locus Report

Biblio print

Add to basket

Go to basket

Tree Display

AceDB Schema

XML Display

Feedback

Gene_locus Report for: drome-CG12869

Drosophila melanogaster (Fruit fly) CG12869 gene for a carboxylesterase may be inactive

Comment
Nucleotide sequence from Celera. Active serine in GHGSGG


Relationship
Family|OtherNon-catalytic_C
Block| C
Position in NCBI Life Tree|Drosophila melanogaster
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Sophophora: N E > melanogaster group: N E > melanogaster subgroup: N E > Drosophila melanogaster: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 1 more: AE003671, AE003814, NM_137125
1 Ncbi-nid : 19922253
2 Ncbi-pid : 19922254, 7303171
1 UniProt : Q8T016
1 Interpro : Q8T016
1 Prodom : Q8T016
1 Pfam : Q8T016
1 PIRSF : Q8T016
1 SUPERFAM : Q8T016
1 EntrezGene : 36616
1 SNP : 36616
1 FlyBase : 0033943
Sequence
Graphical view for this peptide sequence: drome-CG12869
Colored MSA for OtherNon-catalytic_C (raw)
MWNALRIQQILRLLPILIHLSPYISAQQTHIKLEQGDLIGLKVFPDGTRG
AVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIY
DESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEFAYDW
PRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQM
ALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMS
PGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCLRRKSRED
LLRAYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLPPVLLGITSNEGA
FLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWR
YFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTSYAYVFDHSH
SMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRG
AFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVDEAEV
DKLLRGETGAPGLDRSLSRSNRHDTYRAAPSNSYTASNQLDSGYSNHLQM
VYGFWQVLMPLEREEDLRGGGALGQRVRLLEASADAARYRQGFYAMLGLW
FRWTTIFGGRKDEVPSTSGIANVESWRKGGRATKREQDGSGAVESGGGDG
NLEGERREQVLNKQRTRRPRQLQPYDFKITHPIGGAGVGAGFGTGTAGGV
RNGGGTRAGTVSGFGGTLGTVEELLDPVAGQFEPSVAVRNWQYQLTCDKF
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MWNALRIQQILRLLPILIHLSPYISAQQTHIKLEQGDLIGLKVFPDGTRG
AVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIY
DESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEFAYDW
PRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQM
ALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMS
PGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCLRRKSRED
LLRAYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLPPVLLGITSNEGA
FLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWR
YFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTSYAYVFDHSH
SMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRG
AFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVDEAEV
DKLLRGETGAPGLDRSLSRSNRHDTYRAAPSNSYTASNQLDSGYSNHLQM
VYGFWQVLMPLEREEDLRGGGALGQRVRLLEASADAARYRQGFYAMLGLW
FRWTTIFGGRKDEVPSTSGIANVESWRKGGRATKREQDGSGAVESGGGDG
NLEGERREQVLNKQRTRRPRQLQPYDFKITHPIGGAGVGAGFGTGTAGGV
RNGGGTRAGTVSGFGGTLGTVEELLDPVAGQFEPSVAVRNWQYQLTCDKF


Reference
    Title: The genome sequence of Drosophila melanogaster
    Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA and Venter JC <185 more author(s)>
    Ref: Science, 287:2185, 2000 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer