drome-CG5397

 
Drosophila melanogaster (Fruit fly) CG5397 carboxylesterase may be not active

Comment
Nucleotide sequence from Celera Active site SGHGSGAAS. Not very far from cG7529


Relationship
Block C
Drosophila melanogaster position in NCBI Life Tree :
N link to NCBI taxonomic web page and E link to ESTHER gene locus found in this strain.
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Sophophora: N E > melanogaster group: N E > melanogaster subgroup: N E > Drosophila melanogaster: N E

Molecular evidence
Database
No mutation
No structure
No kinetic



1 Genbank : AE003586
1 Ncbi-pid : 7296094
1 UniProtTrembl : Q9VPZ5
1 Interpro : Q9VPZ5
1 Prodom : Q9VPZ5
1 Pfam : Q9VPZ5
1 PIRSF : Q9VPZ5
1 SUPERFAM : Q9VPZ5
1 QuickSwissBlast : Q9VPZ5
1 FlyBase : 0031327
 
Sequence
Graphical view for this peptide sequence: drome-CG5397
Colored MSA for OtherNon-catalytic_C (raw)
MQSQLKRNTLLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDP
VIFARLFDRDARVEGFRNPSTGIYSFLGMHYAEPPVGPLRYSRPVYKRLA
GDFNATKHGPPCIQPHPQFPQRIIGDEDCLLLNVYTPQMPDETTGLPVFV
WIHPGGYRYGSAAQYDATPMAQRGAIVVAPQYRLGSLGIMGDGTKQFDGN
LAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRS
AGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLR
SKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSL
IVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGS
LSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKVPQALNVD
QVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFL
KGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKV
RNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRF
CELSVLGASLSPLSSTSCAGLGNLLGQLGSLGGGLGGTLGGVGSTLGLGG
NGGGGKRGGLGLGIL
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MQSQLKRNTLLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDP
VIFARLFDRDARVEGFRNPSTGIYSFLGMHYAEPPVGPLRYSRPVYKRLA
GDFNATKHGPPCIQPHPQFPQRIIGDEDCLLLNVYTPQMPDETTGLPVFV
WIHPGGYRYGSAAQYDATPMAQRGAIVVAPQYRLGSLGIMGDGTKQFDGN
LAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRS
AGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLR
SKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSL
IVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGS
LSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKVPQALNVD
QVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFL
KGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKV
RNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRF
CELSVLGASLSPLSSTSCAGLGNLLGQLGSLGGGLGGTLGGVGSTLGLGG
NGGGGKRGGLGLGIL

no DNA




Reference
    Title: The genome sequence of Drosophila melanogaster
    Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA and Venter JC <185 more author(s)>
    Ref: Science, 287:2185, 2000 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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