Gene_Locus Report

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Gene_locus Report for: dromo-b4k6s2

Drosophila mojavensis (Fruit fly) GI24125

Comment
only central part Pfam A COesterase 175 710


Relationship
Family|Neuroligin
Block| C
Position in NCBI Life Tree|Drosophila mojavensis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Drosophila [fruit fly, subgenus]: N E > repleta group: N E > mulleri subgroup: N E > mojavensis species complex: N E > Drosophila mojavensis: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : CH933806
1 UniProt : B4K6S2
1 UniProt : B4K6S2
1 Interpro : B4K6S2
1 Pfam : B4K6S2
1 PIRSF : B4K6S2
1 SUPERFAM : B4K6S2
Sequence
Graphical view for this peptide sequence: dromo-b4k6s2
Colored MSA for Neuroligin (raw)
PERRHVVPDKLLYTPELQIKQGRLMGITRRFQVTSGLREVDQYLGLPYAE
APTGSRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDVSGPSSVNMSQGRY
RHLMRLMPYLKTESEDCLYLNVYVPHTDPVAGTKQHAVLVYLHGESFEWN
SGNAYDGSVLASYGEVIVVTVNYRLGVLGFMRPGIDAHNIANYALLDQIA
ALHWIKENIASFGGDNTRVTLMGHSTGAACVNYLMVSPVASGLFHRAILM
SGSAMSDWAASNQSLQLTMQIAQSLDCPLAGHEEDDALLNCLRQRRYQDI
LHIPTSFQQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITES
ESYHTLAALALEEGLSENERDNLLRFYMQSRFDVRPDLALAATLKKYQDM
YNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGH
NSATGPYANLPHSIMGEELAFVFGAPLAPAGPFPSHNYSVQEKLLSEAVM
AYWTNFVKTGNPKAPWKGTFLNSHVLEWDRYDLDWPEFNKRAQAYLNIGI
PPTVGYKYRQIYMNFWNKELPDELNQIAAIQQQQLAGNEVITGHMSKYGP
RDNGAEDPVRTLKLLLQEPVATGSEQLETAAENMYNAPPTFGHVHRLQQL
HQQHQQQQGSEGVATTSVEEATPNSDYGEYGASASPATPGEPIAKSETTL
QLLIALIAIFLVLNVVIYTTFLVRQRRKRSTTM
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

PERRHVVPDKLLYTPELQIKQGRLMGITRRFQVTSGLREVDQYLGLPYAE
APTGSRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDVSGPSSVNMSQGRY
RHLMRLMPYLKTESEDCLYLNVYVPHTDPVAGTKQHAVLVYLHGESFEWN
SGNAYDGSVLASYGEVIVVTVNYRLGVLGFMRPGIDAHNIANYALLDQIA
ALHWIKENIASFGGDNTRVTLMGHSTGAACVNYLMVSPVASGLFHRAILM
SGSAMSDWAASNQSLQLTMQIAQSLDCPLAGHEEDDALLNCLRQRRYQDI
LHIPTSFQQFSTSLGPIVDGHVIPNQPYKVMGHYTEHFSRYDLLFGITES
ESYHTLAALALEEGLSENERDNLLRFYMQSRFDVRPDLALAATLKKYQDM
YNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGH
NSATGPYANLPHSIMGEELAFVFGAPLAPAGPFPSHNYSVQEKLLSEAVM
AYWTNFVKTGNPKAPWKGTFLNSHVLEWDRYDLDWPEFNKRAQAYLNIGI
PPTVGYKYRQIYMNFWNKELPDELNQIAAIQQQQLAGNEVITGHMSKYGP
RDNGAEDPVRTLKLLLQEPVATGSEQLETAAENMYNAPPTFGHVHRLQQL
HQQHQQQQGSEGVATTSVEEATPNSDYGEYGASASPATPGEPIAKSETTL
QLLIALIAIFLVLNVVIYTTFLVRQRRKRSTTM


References
    Title: Assembly reconciliation
    Zimin AV, Smith DR, Sutton G, Yorke JA
    Ref: Bioinformatics, 24:42, 2008 : PubMed

            

    Title: Evolution of genes and genomes on the Drosophila phylogeny
    Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W and MacCallum I <405 more author(s)>
    Ref: Nature, 450:203, 2007 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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