Gene_locus Report for: drowi-b4n023 Drosophila willistoni (Fruit fly) GK24272
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Sophophora: N E > willistoni group: N E > willistoni subgroup: N E > Drosophila willistoni: N E A85-EsteraseD-FGH :
drowi-b4ngb5 Drosophila willistoni (Fruit fly) GK22793 .
ABHD18 :
drowi-b4mxn5 Drosophila willistoni (Fruit fly) GK18793 .
abh_upf0017 :
drowi-b4mwz7 Drosophila willistoni (Fruit fly) GK15564 ,
drowi-b4nn59 Drosophila willistoni (Fruit fly) GK22950 .
ACHE :
drowi-ACHE Drosophila willistoni (Fruit fly) Ace .
Acidic_Lipase :
drowi-b4mp68 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4mrd1 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4mwp2 Drosophila willistoni (Fruit fly) GK15509 ,
drowi-b4mwp6 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4mwq5 Drosophila willistoni (Fruit fly) GK14608 ,
drowi-b4mwr0 Drosophila willistoni (Fruit fly) GK15521 ,
drowi-b4mwr8 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4mwr9 Drosophila willistoni (Fruit fly) GK14601 ,
drowi-b4mwt1 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4n1c8 Drosophila willistoni (Fruit fly) GK24189 ,
drowi-b4n6m1 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4nhz9 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4nja7 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4nja8 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4nja9 Drosophila willistoni (Fruit fly) Lipase ,
drowi-b4nkc8 Drosophila willistoni (Fruit fly) Lipase .
Carboxypeptidase_S10 :
drowi-b4mlc1 Drosophila willistoni (Fruit fly) GK16682 .
Carb_B_Arthropoda :
drowi-b4mjb9 Drosophila willistoni (Fruit fly) GK10360 ,
drowi-b4my54 Drosophila willistoni (Fruit fly) GK22160 ,
drowi-b4n1a7 Drosophila willistoni (Fruit fly) GK24180 incomplete ,
drowi-b4n3s9 Drosophila willistoni (Fruit fly) GK25474 ,
drowi-b4n6n0 Drosophila willistoni (Fruit fly) GK12287 ,
drowi-b4n899.1 Drosophila willistoni (Fruit fly) GK11070 ,
drowi-b4n8a1 Drosophila willistoni (Fruit fly) GK11066 ,
drowi-b4n8a2 Drosophila willistoni (Fruit fly) GK11068 ,
drowi-b4n8a3 Drosophila willistoni (Fruit fly) GK12015 ,
drowi-b4n8a4 Drosophila willistoni (Fruit fly) GK11069 ,
drowi-b4n888 Drosophila willistoni (Fruit fly) GK11082 ,
drowi-b4n889 Drosophila willistoni (Fruit fly) GK11081 ,
drowi-b4n891 Drosophila willistoni (Fruit fly) GK11080 ,
drowi-b4n893 Drosophila willistoni (Fruit fly) GK11077 ,
drowi-b4n895 Drosophila willistoni (Fruit fly) GK11076 ,
drowi-b4n897 Drosophila willistoni (Fruit fly) GK11073 ,
drowi-b4n898 Drosophila willistoni (Fruit fly) GK11072 ,
drowi-b4n899.2 Drosophila willistoni (Fruit fly) GK11071 ,
drowi-b4ng76 Drosophila willistoni (Fruit fly) GK22397 ,
drowi-b4njk8 Drosophila willistoni (Fruit fly) GK13419 ,
drowi-b4nky0 Drosophila willistoni (Fruit fly) GK13999 ,
drowi-b4nnc1 Drosophila willistoni (Fruit fly) GK23289 .
CGI-58_ABHD5_ABHD4 :
drowi-b4mug2 Drosophila willistoni (Fruit fly) GK14854 ,
drowi-b4myh5 Drosophila willistoni (Fruit fly) GK22221 .
DPP4N_Peptidase_S9 :
drowi-b4muj8 Drosophila willistoni (Fruit fly) GK14793 ,
drowi-b4mv18 Drosophila willistoni (Fruit fly) GK14699 ,
drowi-b4ner8 Drosophila willistoni (Fruit fly) GK25230 ,
drowi-b4nl36 Drosophila willistoni (Fruit fly) GK14030 ,
drowi-b4nm27 Drosophila willistoni (Fruit fly) GK10533 .
Glutactin :
drowi-b4n7s6 Drosophila willistoni (Fruit fly) GK18752 ,
drowi-b4n7s7 Drosophila willistoni (Fruit fly) GK18669 ,
drowi-b4n7s8 Drosophila willistoni (Fruit fly) GK18668 .
Juvenile_hormone_esterase :
drowi-b4mqe9 Drosophila willistoni (Fruit fly) GK21858 ,
drowi-b4mqf0.2 Drosophila willistoni (Fruit fly) GK21859 ,
drowi-b4mqf1 Drosophila willistoni (Fruit fly) GK21860 ,
drowi-b4mqf3 Drosophila willistoni (Fruit fly) GK21862 ,
drowi-b4mqf4 Drosophila willistoni (Fruit fly) GK21863 ,
drowi-b4mqf5 Drosophila willistoni (Fruit fly) GK21864 ,
drowi-b4mw85 Drosophila willistoni (Fruit fly) GK15210 ,
drowi-b4nng1 Drosophila willistoni (Fruit fly) GK22895 ,
drowi-b4nng2 Drosophila willistoni (Fruit fly) GK22894 ,
drowi-a0a0q9x0t3 Drosophila willistoni (Fruit fly) GK15211 Uncharacterized protein .
Kynurenine-formamidase :
drowi-b4n7m9 Drosophila willistoni (Fruit fly). N-formylkynurenine formamidase .
LIDHydrolase :
drowi-b4n543 Drosophila willistoni (Fruit fly) GK20500 .
Neuroligin :
drowi-b4n8a9 Drosophila willistoni (Fruit fly) GK12017 ,
drowi-b4n075 Drosophila willistoni (Fruit fly) GK24244 ,
drowi-b4nga7 Drosophila willistoni (Fruit fly) GK22377 .
Neurotactin :
drowi-b4n3x7 Drosophila willistoni (Fruit fly) GK25299 .
NLS3-Tex30 :
drowi-b4myg1 Drosophila willistoni (Fruit fly) GK22215 .
OtherNon-catalytic_C :
drowi-b4mqq6 Drosophila willistoni (Fruit fly) GK21390 ,
drowi-b4mrk3 Drosophila willistoni (Fruit fly) GK15840 ,
drowi-b4mtl5 Drosophila willistoni (Fruit fly) GK23807 ,
drowi-b4mw32 Drosophila willistoni (Fruit fly) GK15185 .
Pectinacetylesterase-Notum :
drowi-b4n6u6 Drosophila willistoni (Fruit fly) GK24122 .
PPase_methylesterase_euk :
drowi-b4n6n7 Drosophila willistoni (Fruit fly) Protein phosphatase methylesterase 1 .
Prolylcarboxypeptidase :
drowi-b4mkt7 Drosophila willistoni (Fruit fly) GK16991 ,
drowi-b4n0d4 Drosophila willistoni (Fruit fly) GK24560 ,
drowi-b4nj18 Drosophila willistoni (Fruit fly) GK13807 ,
drowi-b4nj19 Drosophila willistoni (Fruit fly) GK13808 .
SERHL :
drowi-b4n4x9 Drosophila willistoni (Fruit fly) GK20424 ,
drowi-b4n4y0 Drosophila willistoni (Fruit fly) GK20467 .
Valacyclovir-hydrolase :
drowi-b4nae3 Drosophila willistoni (Fruit fly) GK11394 Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: drowi-b4n023 Colored MSA for Gliotactin (raw)
MLHKLKYRDKLKCSYAICLILILSFLATLTDGQTRDPRFYSRVGVNDYHW
PNPGDPDYRTYTFNDRRYGHYQPNGFGANFPGRNPPGQYPQGMPNEDRFR
FDPNDPNARTQFPGVLAGWREDLQGKQRRDSLTLERDVFVTTNYGQVQGF
KVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPR
PHRGWQLLQAVDFGPACPQPVRYTGATKGVMDMDEDCLYLNVYSPKTGAG
VAQKYPVMVYIHGGEFIRGASNLFQGHMLASFYDVVVVTLNYRLGALGFL
STGDENSPGNYGILDQALALKWVYDNIEFFNGDRESITLFGPGAGGASAG
LLMVAPQTRNIVKRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSI
ESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWAPVLDHNFTLPGDDWYE
GWRQKDWRFLTQTPETLIRAGRFNRNIQYMTGVTTQEAAFFIAQNESLAP
YYEIDGRFFEQKVREHVFRYNYTLNPNGVYEAIKYMYTFWPDPNNNTIMR
DEYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKY
PHDTEHYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYSNFA
RYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQ
YLPTVIGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVTCFFLIVLVVICCI
MWRNAKRQSDRFYDEDVFINGDGIEPETDPRGVDNAHMVTNHHALRSRDN
IYEYRDSPSSKTLASKAHTDTTSLRSPSSLAMTQKSGSQASLKSGISLKE
TNGSLVKSERAATPRSQTNGKSPNPGPIEEKRLLQPISSTPVPQLQAEPV
KRTTPGPAASISGSSRSNTPVPMARTTTTTTATLTTQPPAAGRSVDQPRR
TELVEGIPQTSV
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M L H K L K Y R D K L K C S Y A I C L I L I L S F L A T L T D G Q T R D P R F Y S R V G V N D Y H W P N P G D P D Y R T Y T F N D R R Y G H Y Q P N G F G A N F P G R N P P G Q Y P Q G M P N E D R F R F D P N D P N A R T Q F P G V L A G W R E D L Q G K Q R R D S L T L E R D V F V T T N Y G Q V Q G F K V Y M Y D N P D P K S F Y R P Y H S T V D R V M G E C S V F L G I P Y A L P P T F E G R F K P P R P H R G W Q L L Q A V D F G P A C P Q P V R Y T G A T K G V M D M D E D C L Y L N V Y S P K T G A G V A Q K Y P V M V Y I H G G E F I R G A S N L F Q G H M L A S F Y D V V V V T L N Y R L G A L G F L S T G D E N S P G N Y G I L D Q A L A L K W V Y D N I E F F N G D R E S I T L F G P G A G G A S A G L L M V A P Q T R N I V K R V I A Q S G S A L A D W A L I Q D K Y R A Q N T S R V L G Q L L G C S I E S S W K L V N C L R T G R S F Y E L G N A E F S P Q V G S F P W A P V L D H N F T L P G D D W Y E G W R Q K D W R F L T Q T P E T L I R A G R F N R N I Q Y M T G V T T Q E A A F F I A Q N E S L A P Y Y E I D G R F F E Q K V R E H V F R Y N Y T L N P N G V Y E A I K Y M Y T F W P D P N N N T I M R D E Y I N M L S D L Y Y R A P V D Q M V K L M L E Q K V P V Y M Y V L N T T V E A L N L P Q W R K Y P H D T E H Y F L T G A P F M D T E F F P K K E H L Q R N M W T D N D R N M S H F F M Q T Y S N F A R Y G N P T P Q Q V L G M H F Q R A Y Q G E I R Y L N I N T T Y N S S I L L N Y R Q T E C A F W T Q Y L P T V I G V L V P T Y P P T T E Y W W E P K E P L Q I A F W S M S V T C F F L I V L V V I C C I M W R N A K R Q S D R F Y D E D V F I N G D G I E P E T D P R G V D N A H M V T N H H A L R S R D N I Y E Y R D S P S S K T L A S K A H T D T T S L R S P S S L A M T Q K S G S Q A S L K S G I S L K E T N G S L V K S E R A A T P R S Q T N G K S P N P G P I E E K R L L Q P I S S T P V P Q L Q A E P V K R T T P G P A A S I S G S S R S N T P V P M A R T T T T T T A T L T T Q P P A A G R S V D Q P R R T E L V E G I P Q T S V
References
Title: Assembly reconciliationZimin AV , Smith DR , Sutton G , Yorke JA Ref: Bioinformatics, 24 :42, 2008 : PubMed Abstract ESTHER: Zimin_2008_Bioinformatics_24_42 PubMedSearch: Zimin 2008 Bioinformatics 24 42 PubMedID: 18057021 Gene_locus related to this paper: droan-ACHE ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
droan-b3lyh7 ,
droan-b3lyh9 ,
droan-b3lyi0 ,
droan-b3lyi2 ,
droan-b3lyi3 ,
droan-b3lyi4 ,
droan-b3lyx4 ,
droan-b3lyx5 ,
droan-b3lyx6 ,
droan-b3lyx7 ,
droan-b3lyx9 ,
droan-b3lz72 ,
droan-b3m4e3 ,
droan-b3m5w1 ,
droan-b3m6i7 ,
droan-b3m7v2 ,
droan-b3m9p3 ,
droan-b3m524 ,
droan-b3m635 ,
droan-b3mdh7 ,
droan-b3mdw8 ,
droan-b3mee1 ,
droan-b3mf47 ,
droan-b3mf48 ,
droan-b3mg94 ,
droan-b3mgn6 ,
droan-b3mii3 ,
droan-b3mkr0 ,
droan-b3ml20 ,
droan-b3mly4 ,
droan-b3mly5 ,
droan-b3mly6 ,
droan-b3mnb5 ,
droan-b3muw4 ,
droan-b3muw8 ,
droan-b3n2j7 ,
droan-c5idb2 ,
droer-ACHE ,
droer-b3n5y4 ,
droer-b3n7d2 ,
droer-b3n7d3 ,
droer-b3n7d4 ,
droer-b3n7k8 ,
droer-b3n8e4 ,
droer-b3n8f7 ,
droer-b3n8f8 ,
droer-b3n9e1 ,
droer-b3n612 ,
droer-b3nar5 ,
droer-b3nb91 ,
droer-b3nct9 ,
droer-b3ndh9 ,
droer-b3ndq8 ,
droer-b3ne97 ,
droer-b3nfq9 ,
droer-b3nmh4 ,
droer-b3nmy2 ,
droer-b3npx2 ,
droer-b3npx3 ,
droer-b3nq76 ,
droer-b3nr28 ,
droer-b3nst4 ,
droer-b3nyp5.1 ,
droer-b3nyp5.2 ,
droer-b3nyp6 ,
droer-b3nyp7 ,
droer-b3nyp8 ,
droer-b3nyp9 ,
droer-b3nyq3 ,
droer-b3nz06 ,
droer-b3nz14 ,
droer-b3nzj0 ,
droer-b3p2x6 ,
droer-b3p2x7 ,
droer-b3p2x9 ,
droer-b3p2y1 ,
droer-b3p2y2 ,
droer-b3p7b4 ,
droer-EST6 ,
droer-q670j5 ,
drogr-ACHE ,
drogr-b4iww3 ,
drogr-b4iwy3 ,
drogr-b4ixf7 ,
drogr-b4ixh4 ,
drogr-b4j2u8 ,
drogr-b4j3v3 ,
drogr-b4j4g7 ,
drogr-b4j4x9 ,
drogr-b4j6e6 ,
drogr-b4j9c9 ,
drogr-b4j9y4 ,
drogr-b4j156 ,
drogr-b4j685 ,
drogr-b4ja76 ,
drogr-b4jcf0 ,
drogr-b4jcf1 ,
drogr-b4jdh6 ,
drogr-b4jdz1 ,
drogr-b4jdz2 ,
drogr-b4jdz4 ,
drogr-b4jf76 ,
drogr-b4jf79 ,
drogr-b4jf80 ,
drogr-b4jf81 ,
drogr-b4jf82 ,
drogr-b4jf83 ,
drogr-b4jf84 ,
drogr-b4jf85 ,
drogr-b4jf87 ,
drogr-b4jf91 ,
drogr-b4jf92 ,
drogr-b4jg66 ,
drogr-b4jnh9 ,
drogr-b4jpc6 ,
drogr-b4jql2 ,
drogr-b4jrh5 ,
drogr-b4jth3 ,
drogr-b4jti1 ,
drogr-b4jul5 ,
dromo-ACHE ,
dromo-b4k6q8 ,
dromo-b4k6q9 ,
dromo-b4k6r1 ,
dromo-b4k6r3 ,
dromo-b4k6r4 ,
dromo-b4k6r5 ,
dromo-b4k6r6 ,
dromo-b4k6r7 ,
dromo-b4k6r8 ,
dromo-b4k6r9 ,
dromo-b4k6s0 ,
dromo-b4k6s1 ,
dromo-b4k6s2 ,
dromo-b4k9c7 ,
dromo-b4k9d3 ,
dromo-b4ka74 ,
dromo-b4kaj4 ,
dromo-b4kdg2 ,
dromo-b4kdh4 ,
dromo-b4kdh5 ,
dromo-b4kdh6 ,
dromo-A0A0Q9XDF2 ,
dromo-b4kdh8.1 ,
dromo-b4kdh8.2 ,
dromo-b4kg04 ,
dromo-b4kg05 ,
dromo-b4kg06 ,
dromo-b4kg16 ,
dromo-b4kh20 ,
dromo-b4kh21 ,
dromo-b4kik0 ,
dromo-b4kjx0 ,
dromo-b4kki1 ,
dromo-b4klv8 ,
dromo-b4kp08 ,
dromo-b4kqa6 ,
dromo-b4kqa7 ,
dromo-b4kqa8 ,
dromo-b4kqh1 ,
dromo-b4kst4 ,
dromo-b4ksy6 ,
dromo-b4ktf5 ,
dromo-b4ktf6 ,
dromo-b4kvw2 ,
dromo-b4kxz6 ,
dromo-b4ky12 ,
dromo-b4ky36 ,
dromo-b4l0n8 ,
dromo-b4l6l9 ,
dromo-b4l084 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgn2 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lrp6 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lt32 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4m0s0 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mfa4 ,
drovi-estes ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myh5 ,
drowi-b4n1a7 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4njk8 ,
drowi-b4nky0 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-q71d76 ,
drowi-a0a0q9x0t3 ,
drovi-b4mcn9 Abstract
MOTIVATION: Many genomes are sequenced by a collaboration of several centers, and then each center produces an assembly using their own assembly software. The collaborators then pick the draft assembly that they judge to be the best and the information contained in the other assemblies is usually not used. METHODS: We have developed a technique that we call assembly reconciliation that can merge draft genome assemblies. It takes one draft assembly, detects apparent errors, and, when possible, patches the problem areas using pieces from alternative draft assemblies. It also closes gaps in places where one of the alternative assemblies has spanned the gap correctly. RESULTS: Using the Assembly Reconciliation technique, we produced reconciled assemblies of six Drosophila species in collaboration with Agencourt Bioscience and The J. Craig Venter Institute. These assemblies are now the official (CAF1) assemblies used for analysis. We also produced a reconciled assembly of Rhesus Macaque genome, and this assembly is available from our website http://www.genome.umd.edu. AVAILABILITY: The reconciliation software is available for download from http://www.genome.umd.edu/software.htm
Title: Evolution of genes and genomes on the Drosophila phylogenyClark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W and MacCallum I <405 more author(s)> Clark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W , Iyer VN , Pollard DA , Sackton TB , Larracuente AM , Singh ND , Abad JP , Abt DN , Adryan B , Aguade M , Akashi H , Anderson WW , Aquadro CF , Ardell DH , Arguello R , Artieri CG , Barbash DA , Barker D , Barsanti P , Batterham P , Batzoglou S , Begun D , Bhutkar A , Blanco E , Bosak SA , Bradley RK , Brand AD , Brent MR , Brooks AN , Brown RH , Butlin RK , Caggese C , Calvi BR , Bernardo de Carvalho A , Caspi A , Castrezana S , Celniker SE , Chang JL , Chapple C , Chatterji S , Chinwalla A , Civetta A , Clifton SW , Comeron JM , Costello JC , Coyne JA , Daub J , David RG , Delcher AL , Delehaunty K , Do CB , Ebling H , Edwards K , Eickbush T , Evans JD , Filipski A , Findeiss S , Freyhult E , Fulton L , Fulton R , Garcia AC , Gardiner A , Garfield DA , Garvin BE , Gibson G , Gilbert D , Gnerre S , Godfrey J , Good R , Gotea V , Gravely B , Greenberg AJ , Griffiths-Jones S , Gross S , Guigo R , Gustafson EA , Haerty W , Hahn MW , Halligan DL , Halpern AL , Halter GM , Han MV , Heger A , Hillier L , Hinrichs AS , Holmes I , Hoskins RA , Hubisz MJ , Hultmark D , Huntley MA , Jaffe DB , Jagadeeshan S , Jeck WR , Johnson J , Jones CD , Jordan WC , Karpen GH , Kataoka E , Keightley PD , Kheradpour P , Kirkness EF , Koerich LB , Kristiansen K , Kudrna D , Kulathinal RJ , Kumar S , Kwok R , Lander E , Langley CH , Lapoint R , Lazzaro BP , Lee SJ , Levesque L , Li R , Lin CF , Lin MF , Lindblad-Toh K , Llopart A , Long M , Low L , Lozovsky E , Lu J , Luo M , Machado CA , Makalowski W , Marzo M , Matsuda M , Matzkin L , McAllister B , McBride CS , McKernan B , McKernan K , Mendez-Lago M , Minx P , Mollenhauer MU , Montooth K , Mount SM , Mu X , Myers E , Negre B , Newfeld S , Nielsen R , Noor MA , O'Grady P , Pachter L , Papaceit M , Parisi MJ , Parisi M , Parts L , Pedersen JS , Pesole G , Phillippy AM , Ponting CP , Pop M , Porcelli D , Powell JR , Prohaska S , Pruitt K , Puig M , Quesneville H , Ram KR , Rand D , Rasmussen MD , Reed LK , Reenan R , Reily A , Remington KA , Rieger TT , Ritchie MG , Robin C , Rogers YH , Rohde C , Rozas J , Rubenfield MJ , Ruiz A , Russo S , Salzberg SL , Sanchez-Gracia A , Saranga DJ , Sato H , Schaeffer SW , Schatz MC , Schlenke T , Schwartz R , Segarra C , Singh RS , Sirot L , Sirota M , Sisneros NB , Smith CD , Smith TF , Spieth J , Stage DE , Stark A , Stephan W , Strausberg RL , Strempel S , Sturgill D , Sutton G , Sutton GG , Tao W , Teichmann S , Tobari YN , Tomimura Y , Tsolas JM , Valente VL , Venter E , Venter JC , Vicario S , Vieira FG , Vilella AJ , Villasante A , Walenz B , Wang J , Wasserman M , Watts T , Wilson D , Wilson RK , Wing RA , Wolfner MF , Wong A , Wong GK , Wu CI , Wu G , Yamamoto D , Yang HP , Yang SP , Yorke JA , Yoshida K , Zdobnov E , Zhang P , Zhang Y , Zimin AV , Baldwin J , Abdouelleil A , Abdulkadir J , Abebe A , Abera B , Abreu J , Acer SC , Aftuck L , Alexander A , An P , Anderson E , Anderson S , Arachi H , Azer M , Bachantsang P , Barry A , Bayul T , Berlin A , Bessette D , Bloom T , Blye J , Boguslavskiy L , Bonnet C , Boukhgalter B , Bourzgui I , Brown A , Cahill P , Channer S , Cheshatsang Y , Chuda L , Citroen M , Collymore A , Cooke P , Costello M , D'Aco K , Daza R , De Haan G , DeGray S , DeMaso C , Dhargay N , Dooley K , Dooley E , Doricent M , Dorje P , Dorjee K , Dupes A , Elong R , Falk J , Farina A , Faro S , Ferguson D , Fisher S , Foley CD , Franke A , Friedrich D , Gadbois L , Gearin G , Gearin CR , Giannoukos G , Goode T , Graham J , Grandbois E , Grewal S , Gyaltsen K , Hafez N , Hagos B , Hall J , Henson C , Hollinger A , Honan T , Huard MD , Hughes L , Hurhula B , Husby ME , Kamat A , Kanga B , Kashin S , Khazanovich D , Kisner P , Lance K , Lara M , Lee W , Lennon N , Letendre F , LeVine R , Lipovsky A , Liu X , Liu J , Liu S , Lokyitsang T , Lokyitsang Y , Lubonja R , Lui A , Macdonald P , Magnisalis V , Maru K , Matthews C , McCusker W , McDonough S , Mehta T , Meldrim J , Meneus L , Mihai O , Mihalev A , Mihova T , Mittelman R , Mlenga V , Montmayeur A , Mulrain L , Navidi A , Naylor J , Negash T , Nguyen T , Nguyen N , Nicol R , Norbu C , Norbu N , Novod N , O'Neill B , Osman S , Markiewicz E , Oyono OL , Patti C , Phunkhang P , Pierre F , Priest M , Raghuraman S , Rege F , Reyes R , Rise C , Rogov P , Ross K , Ryan E , Settipalli S , Shea T , Sherpa N , Shi L , Shih D , Sparrow T , Spaulding J , Stalker J , Stange-Thomann N , Stavropoulos S , Stone C , Strader C , Tesfaye S , Thomson T , Thoulutsang Y , Thoulutsang D , Topham K , Topping I , Tsamla T , Vassiliev H , Vo A , Wangchuk T , Wangdi T , Weiand M , Wilkinson J , Wilson A , Yadav S , Young G , Yu Q , Zembek L , Zhong D , Zimmer A , Zwirko Z , Alvarez P , Brockman W , Butler J , Chin C , Grabherr M , Kleber M , Mauceli E , MacCallum I (- 405) Ref: Nature, 450 :203, 2007 : PubMed Abstract ESTHER: Clark_2007_Nature_450_203 PubMedSearch: Clark 2007 Nature 450 203 PubMedID: 17994087 Gene_locus related to this paper: droan-ACHE ,
droan-b3lx10 ,
droan-b3lx75 ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
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drogr-b4k2r1 ,
drogr-b4k234 ,
drogr-b4k235 ,
drome-BEM46 ,
drome-CG3734 ,
drome-CG9953 ,
drome-CG11626 ,
drome-GH02439 ,
dromo-ACHE ,
dromo-b4k6a7 ,
dromo-b4k6a8 ,
dromo-b4k6q8 ,
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drosi-b4qzn7 ,
drosi-b4qzn8 ,
drosi-b4qzp2 ,
drosi-b4qzp3 ,
drosi-b4qzp4 ,
drosi-b4qzp5 ,
drosi-b4qzp6 ,
drosi-b4qzp7 ,
drosi-b4r1a4 ,
drosi-b4r025 ,
drosi-b4r207 ,
drosi-b4r662 ,
drosi-este6 ,
drosi-q670k8 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lf33 ,
drovi-b4lf51 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgc6 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgk5 ,
drovi-b4lgn2 ,
drovi-b4lh17 ,
drovi-b4lh18 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4llm5 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lnr4 ,
drovi-b4lp47 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lqc6 ,
drovi-b4lr00 ,
drovi-b4lrp6 ,
drovi-b4lrw2 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lsq5 ,
drovi-b4lt32 ,
drovi-b4ltr1 ,
drovi-b4lui7 ,
drovi-b4lui9 ,
drovi-b4luj8 ,
drovi-b4luk0 ,
drovi-b4luk3 ,
drovi-b4luk8 ,
drovi-b4luk9 ,
drovi-b4lul0 ,
drovi-b4lve2 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4lyq2 ,
drovi-b4lyq3 ,
drovi-b4lz07 ,
drovi-b4lz13 ,
drovi-b4lz14 ,
drovi-b4lz15 ,
drovi-b4m0j7 ,
drovi-b4m0s0 ,
drovi-b4m2b6 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m6b9 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m564 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mb87 ,
drovi-b4mc71 ,
drovi-b4mfa4 ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mkt7 ,
drowi-b4mlc1 ,
drowi-b4mp68 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrd1 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4muj8 ,
drowi-b4mv18 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwp2 ,
drowi-b4mwp6 ,
drowi-b4mwq5 ,
drowi-b4mwr0 ,
drowi-b4mwr8 ,
drowi-b4mwr9 ,
drowi-b4mwt1 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myg1 ,
drowi-b4myh5 ,
drowi-b4n0d4 ,
drowi-b4n1a7 ,
drowi-b4n1c8 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n4x9 ,
drowi-b4n4y0 ,
drowi-b4n6m1 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4nae3 ,
drowi-b4ner8 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4nhz9 ,
drowi-b4nj18 ,
drowi-b4nj19 ,
drowi-b4nja7 ,
drowi-b4nja8 ,
drowi-b4nja9 ,
drowi-b4njk8 ,
drowi-b4nkc8 ,
drowi-b4nky0 ,
drowi-b4nl36 ,
drowi-b4nm27 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-ACHE ,
droya-aes04 ,
droya-b4itg2 ,
droya-b4itg6 ,
droya-b4itu9 ,
droya-b4iuv4 ,
droya-b4iuv5 ,
droya-b4nxe6 ,
droya-b4nxg5 ,
droya-b4nxg6 ,
droya-b4nxg8 ,
droya-b4nxw4 ,
droya-b4ny57 ,
droya-b4ny58 ,
droya-b4ny86 ,
droya-b4nzz8 ,
droya-b4p0b5 ,
droya-b4p0q9 ,
droya-b4p0r0 ,
droya-b4p0r7 ,
droya-b4p0r8 ,
droya-b4p0r9 ,
droya-b4p0s0 ,
droya-b4p0s2 ,
droya-b4p0t0 ,
droya-b4p0t1 ,
droya-b4p3h4 ,
droya-b4p3x8 ,
droya-b4p5g8 ,
droya-b4p6c9 ,
droya-b4p6l9 ,
droya-b4p6r1 ,
droya-b4p6r2 ,
droya-b4p7u4 ,
droya-b4p8w7 ,
droya-b4p023 ,
droya-b4p241 ,
droya-b4p774 ,
droya-b4pat9 ,
droya-b4pbl1 ,
droya-b4pd22 ,
droya-b4pd70 ,
droya-b4pdm8 ,
droya-b4pet9 ,
droya-b4pff9 ,
droya-b4pga7 ,
droya-b4pgu0 ,
droya-b4pig3 ,
droya-b4pjt8 ,
droya-b4pka2 ,
droya-b4plh2 ,
droya-b4pma3 ,
droya-b4pmv3 ,
droya-b4pmv4 ,
droya-b4pmv5 ,
droya-b4pn92 ,
droya-b4pp65 ,
droya-b4ppc5 ,
droya-b4ppc6 ,
droya-b4ppc7 ,
droya-b4ppc8 ,
droya-b4pq03 ,
droya-b4prg6B ,
droya-b4prg9 ,
droya-b4prh3 ,
droya-b4prh4 ,
droya-b4prh6 ,
droya-b4prh7 ,
droya-b4psz8 ,
droya-b4psz9 ,
droya-b4pv22 ,
droya-b4q0g5 ,
droya-b4q246 ,
droya-EST6 ,
droya-q71d76 ,
drowi-b4n7m9 ,
drope-b4gkk1 ,
droer-b3n5s3 ,
drose-b4i1w5 ,
drowi-a0a0q9x0t3 ,
drogr-b4jvm7 ,
dromo-b4ku70 ,
drovi-b4mcn9 ,
drovi-b4lty2 ,
drogr-b4jdu1 ,
drovi-a0a0q9wiq8 ,
dromo-b4kf70 ,
drosi-b2zi86 ,
droya-b4p2y4 ,
drose-b2zic5 ,
droer-b3n895 Abstract
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
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