Gene_locus Report for: droya-aes04 Drosophila yakuba (Fruit fly)alpha-esterase 4a (aE4a) gene, partial cds
Comment
coorected with genome Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Holometabola: N E > Diptera: N E > Brachycera: N E > Muscomorpha: N E > Eremoneura: N E > Cyclorrhapha: N E > Schizophora: N E > Acalyptratae: N E > Ephydroidea: N E > Drosophilidae: N E > Drosophilinae: N E > Drosophilini: N E > Drosophila [fruit fly, genus]: N E > Sophophora: N E > melanogaster group: N E > melanogaster subgroup: N E > Drosophila yakuba: N E A85-EsteraseD-FGH :
droya-b4pp65 Drosophila yakuba (Fruit fly) GE25088 .
ABHD18 :
droya-b4pgu0 Drosophila yakuba (Fruit fly) GE21919 .
abh_upf0017 :
droya-b4nxe6 Drosophila yakuba (Fruit fly) GE18216 ,
droya-b4p3x8 Drosophila yakuba (Fruit fly) GE19258 .
ACHE :
droya-ACHE Drosophila yakuba (Fruit fly); Drosophila ficusphila acetylcholinesterase GE24460 .
Acidic_Lipase :
droya-b4nxw4 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0q9 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0r0 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0r7 Drosophila yakuba (Fruit fly) GE13495 ,
droya-b4p0r8 Drosophila yakuba (Fruit fly) GE18474 ,
droya-b4p0r9 Drosophila yakuba (Fruit fly) GE18475 ,
droya-b4p0s0 Drosophila yakuba (Fruit fly) GE18476 ,
droya-b4p0s2 Drosophila yakuba (Fruit fly) GE18478 ,
droya-b4p0t0 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p0t1 Drosophila yakuba (Fruit fly) GE13417 ,
droya-b4p6c9 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4p7u4 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4pet9 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc5 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc6 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc7 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4ppc8 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4pq03 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4psz8 Drosophila yakuba (Fruit fly) Lipase ,
droya-b4psz9 Drosophila yakuba (Fruit fly) Lipase .
Carb_B_Arthropoda :
droya-b4iuv4 Drosophila yakuba (Fruit fly) DyakGE11183 ,
droya-b4iuv5 Drosophila yakuba (Fruit fly) GE11113 ,
droya-b4ny57 Drosophila yakuba (Fruit fly) GE18855 ,
droya-b4p5g8 Drosophila yakuba (Fruit fly) GE13995 ,
droya-b4p8w7 Drosophila yakuba (Fruit fly) GE13694 ,
droya-b4pdm8 Drosophila yakuba (Fruit fly) GE19762 ,
droya-b4pga7 Drosophila yakuba (Fruit fly) Est-7 ,
droya-b4plh2 Drosophila yakuba (Fruit fly) GE26073 ,
droya-b4pn92 Drosophila yakuba (Fruit fly) GE23951 ,
droya-b4prg6B Drosophila yakuba (Fruit fly) GE25781 ,
droya-b4prg9 Drosophila yakuba (Fruit fly) GE25783 ,
droya-b4prh3 Drosophila yakuba (Fruit fly) GE24932 ,
droya-b4prh4 Drosophila yakuba (Fruit fly) GE25786 ,
droya-b4prh6 Drosophila yakuba (Fruit fly) GE25790 GE14824 ,
droya-b4prh7 Drosophila yakuba (Fruit fly) GE25791 ,
droya-b4q0g5 Drosophila yakuba (Fruit fly) GE16876 ,
droya-EST6 Drosophila yakuba (Fruit fly) (and Drosophila santomea) b-carboxyl esterase (EC 3.1.1.1) .
CGI-58_ABHD5_ABHD4 :
droya-b4p241 Drosophila yakuba (Fruit fly) GE19151 .
DPP4N_Peptidase_S9 :
droya-b4p0b5 Drosophila yakuba (Fruit fly) GE18428 ,
droya-b4p023 Drosophila yakuba (Fruit fly) GE25657 ,
droya-b4pig3 Drosophila yakuba (Fruit fly) GE22026 ,
droya-b4pv22 Drosophila yakuba (Fruit fly) GE10760 ,
droya-b4q246 Drosophila yakuba (Fruit fly) GE15628 .
Duf_829 :
droya-q71d76 Drosophila yakuba (Fruit fly) 1(2)k09913 Drosophila erecta L(2)k09913-PA (Lethal (2) k09913) .
Gliotactin :
droya-b4ny86 Drosophila yakuba (Fruit fly) GE19390 .
Glutactin :
droya-b4nxg5 Drosophila yakuba (Fruit fly) GE18789 ,
droya-b4nxg6 Drosophila yakuba (Fruit fly) GE10861 ,
droya-b4nxg8 Drosophila yakuba (Fruit fly) GE10839 .
Juvenile_hormone_esterase :
droya-b4p6r1 Drosophila yakuba (Fruit fly) GE11755 ,
droya-b4p6r2 Drosophila yakuba (Fruit fly) GE11753 .
LIDHydrolase :
droya-b4pd70 Drosophila yakuba (Fruit fly) GE20970 .
Neuroligin :
droya-b4nzz8 Drosophila yakuba (Fruit fly) GE14187 .
Neurotactin :
droya-b4pka2 Drosophila yakuba (Fruit fly) GE19873 .
NLS3-Tex30 :
droya-b4p6l9 Drosophila yakuba (Fruit fly) GE12338 .
OtherNon-catalytic_C :
droya-b4ny58 Drosophila yakuba (Fruit fly) GE10446 ,
droya-b4p3h4 Drosophila yakuba (Fruit fly) GE17517 ,
droya-b4p774 Drosophila yakuba (Fruit fly) GE13597 ,
droya-b4pat9 Drosophila yakuba (Fruit fly) GE11486 .
Pectinacetylesterase-Notum :
droya-b4itu9 Drosophila yakuba (Fruit fly) GE22884 ,
droya-b4pd22 Drosophila yakuba (Fruit fly) GE19800 .
PPase_methylesterase_euk :
droya-b4pff9 Drosophila yakuba (Fruit fly) Protein phosphatase methylesterase 1 .
Prolylcarboxypeptidase :
droya-b4pbl1 Drosophila yakuba (Fruit fly) GE12590 ,
droya-b4pjt8 Drosophila yakuba (Fruit fly) GE21585 ,
droya-b4pmv3 Drosophila yakuba (Fruit fly) GE25599 ,
droya-b4pmv4 Drosophila yakuba (Fruit fly) GE25600 ,
droya-b4pmv5 Drosophila yakuba (Fruit fly) GE25604 .
SERHL :
droya-b4itg2 Drosophila yakuba (Fruit fly) GE23049 ,
droya-b4itg6 Drosophila yakuba (Fruit fly); Drosophila ficusphila (Fruit fly) GE22964 ,
droya-b4p2y4 Drosophila yakuba (Fruit fly). Uncharacterized protein .
Valacyclovir-hydrolase :
droya-b4pma3 Drosophila yakuba (Fruit fly) GE24034 Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: droya-aes04 Colored MSA for Carb_B_Arthropoda (raw)
PLGSLRFKEPKELQPWTGTRDCSKPASKCLQLASLTKMVEGSEDCLYLNI
TVKTLQSEKPLPLMVYIHGGQFLRGDASRQTWGPDYFMEENVIHVSIGYR
SGPFGFFSFADPSLDIPGNAALKDIIMALRWIKANATNFNGDPDNITIFG
HSSGSVLVHMLLASPQAEGLFHKAILMAGFFMELNPLPHLEFRLAKRLGH
EGNNVDSQVLEFLLKADPQLLVSGDVFSPEEKAEGINLSFKPTVEKYATP
NAVLLAEPKELLRNSWSNRIPIILGANTDEGLLSIVGFKTDPSVLQGFRE
NPEKVLPFGLKITCNSAEKREMGLKMLEYFCQANGKQLSLYHFDAIKDIF
THHTFHSLYRMIQSRLAYAQAPTYFYRFDFDSPDFNLYRNRFWGKEQRGV
NHVDELGYIYVMPDTFKLDKSRPEFTTICRMVSMFVHFAATSDPNSPLTK
PLVDWKPVSSGPARMVLNIGEQLEFISHNMPKLELYDQLLEQAGVSLI
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
P L G S L R F K E P K E L Q P W T G T R D C S K P A S K C L Q L A S L T K M V E G S E D C L Y L N I T V K T L Q S E K P L P L M V Y I H G G Q F L R G D A S R Q T W G P D Y F M E E N V I H V S I G Y R S G P F G F F S F A D P S L D I P G N A A L K D I I M A L R W I K A N A T N F N G D P D N I T I F G H S S G S V L V H M L L A S P Q A E G L F H K A I L M A G F F M E L N P L P H L E F R L A K R L G H E G N N V D S Q V L E F L L K A D P Q L L V S G D V F S P E E K A E G I N L S F K P T V E K Y A T P N A V L L A E P K E L L R N S W S N R I P I I L G A N T D E G L L S I V G F K T D P S V L Q G F R E N P E K V L P F G L K I T C N S A E K R E M G L K M L E Y F C Q A N G K Q L S L Y H F D A I K D I F T H H T F H S L Y R M I Q S R L A Y A Q A P T Y F Y R F D F D S P D F N L Y R N R F W G K E Q R G V N H V D E L G Y I Y V M P D T F K L D K S R P E F T T I C R M V S M F V H F A A T S D P N S P L T K P L V D W K P V S S G P A R M V L N I G E Q L E F I S H N M P K L E L Y D Q L L E Q A G V S L I
References
Title: Evolution of genes and genomes on the Drosophila phylogenyClark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W and MacCallum I <405 more author(s)> Clark AG , Eisen MB , Smith DR , Bergman CM , Oliver B , Markow TA , Kaufman TC , Kellis M , Gelbart W , Iyer VN , Pollard DA , Sackton TB , Larracuente AM , Singh ND , Abad JP , Abt DN , Adryan B , Aguade M , Akashi H , Anderson WW , Aquadro CF , Ardell DH , Arguello R , Artieri CG , Barbash DA , Barker D , Barsanti P , Batterham P , Batzoglou S , Begun D , Bhutkar A , Blanco E , Bosak SA , Bradley RK , Brand AD , Brent MR , Brooks AN , Brown RH , Butlin RK , Caggese C , Calvi BR , Bernardo de Carvalho A , Caspi A , Castrezana S , Celniker SE , Chang JL , Chapple C , Chatterji S , Chinwalla A , Civetta A , Clifton SW , Comeron JM , Costello JC , Coyne JA , Daub J , David RG , Delcher AL , Delehaunty K , Do CB , Ebling H , Edwards K , Eickbush T , Evans JD , Filipski A , Findeiss S , Freyhult E , Fulton L , Fulton R , Garcia AC , Gardiner A , Garfield DA , Garvin BE , Gibson G , Gilbert D , Gnerre S , Godfrey J , Good R , Gotea V , Gravely B , Greenberg AJ , Griffiths-Jones S , Gross S , Guigo R , Gustafson EA , Haerty W , Hahn MW , Halligan DL , Halpern AL , Halter GM , Han MV , Heger A , Hillier L , Hinrichs AS , Holmes I , Hoskins RA , Hubisz MJ , Hultmark D , Huntley MA , Jaffe DB , Jagadeeshan S , Jeck WR , Johnson J , Jones CD , Jordan WC , Karpen GH , Kataoka E , Keightley PD , Kheradpour P , Kirkness EF , Koerich LB , Kristiansen K , Kudrna D , Kulathinal RJ , Kumar S , Kwok R , Lander E , Langley CH , Lapoint R , Lazzaro BP , Lee SJ , Levesque L , Li R , Lin CF , Lin MF , Lindblad-Toh K , Llopart A , Long M , Low L , Lozovsky E , Lu J , Luo M , Machado CA , Makalowski W , Marzo M , Matsuda M , Matzkin L , McAllister B , McBride CS , McKernan B , McKernan K , Mendez-Lago M , Minx P , Mollenhauer MU , Montooth K , Mount SM , Mu X , Myers E , Negre B , Newfeld S , Nielsen R , Noor MA , O'Grady P , Pachter L , Papaceit M , Parisi MJ , Parisi M , Parts L , Pedersen JS , Pesole G , Phillippy AM , Ponting CP , Pop M , Porcelli D , Powell JR , Prohaska S , Pruitt K , Puig M , Quesneville H , Ram KR , Rand D , Rasmussen MD , Reed LK , Reenan R , Reily A , Remington KA , Rieger TT , Ritchie MG , Robin C , Rogers YH , Rohde C , Rozas J , Rubenfield MJ , Ruiz A , Russo S , Salzberg SL , Sanchez-Gracia A , Saranga DJ , Sato H , Schaeffer SW , Schatz MC , Schlenke T , Schwartz R , Segarra C , Singh RS , Sirot L , Sirota M , Sisneros NB , Smith CD , Smith TF , Spieth J , Stage DE , Stark A , Stephan W , Strausberg RL , Strempel S , Sturgill D , Sutton G , Sutton GG , Tao W , Teichmann S , Tobari YN , Tomimura Y , Tsolas JM , Valente VL , Venter E , Venter JC , Vicario S , Vieira FG , Vilella AJ , Villasante A , Walenz B , Wang J , Wasserman M , Watts T , Wilson D , Wilson RK , Wing RA , Wolfner MF , Wong A , Wong GK , Wu CI , Wu G , Yamamoto D , Yang HP , Yang SP , Yorke JA , Yoshida K , Zdobnov E , Zhang P , Zhang Y , Zimin AV , Baldwin J , Abdouelleil A , Abdulkadir J , Abebe A , Abera B , Abreu J , Acer SC , Aftuck L , Alexander A , An P , Anderson E , Anderson S , Arachi H , Azer M , Bachantsang P , Barry A , Bayul T , Berlin A , Bessette D , Bloom T , Blye J , Boguslavskiy L , Bonnet C , Boukhgalter B , Bourzgui I , Brown A , Cahill P , Channer S , Cheshatsang Y , Chuda L , Citroen M , Collymore A , Cooke P , Costello M , D'Aco K , Daza R , De Haan G , DeGray S , DeMaso C , Dhargay N , Dooley K , Dooley E , Doricent M , Dorje P , Dorjee K , Dupes A , Elong R , Falk J , Farina A , Faro S , Ferguson D , Fisher S , Foley CD , Franke A , Friedrich D , Gadbois L , Gearin G , Gearin CR , Giannoukos G , Goode T , Graham J , Grandbois E , Grewal S , Gyaltsen K , Hafez N , Hagos B , Hall J , Henson C , Hollinger A , Honan T , Huard MD , Hughes L , Hurhula B , Husby ME , Kamat A , Kanga B , Kashin S , Khazanovich D , Kisner P , Lance K , Lara M , Lee W , Lennon N , Letendre F , LeVine R , Lipovsky A , Liu X , Liu J , Liu S , Lokyitsang T , Lokyitsang Y , Lubonja R , Lui A , Macdonald P , Magnisalis V , Maru K , Matthews C , McCusker W , McDonough S , Mehta T , Meldrim J , Meneus L , Mihai O , Mihalev A , Mihova T , Mittelman R , Mlenga V , Montmayeur A , Mulrain L , Navidi A , Naylor J , Negash T , Nguyen T , Nguyen N , Nicol R , Norbu C , Norbu N , Novod N , O'Neill B , Osman S , Markiewicz E , Oyono OL , Patti C , Phunkhang P , Pierre F , Priest M , Raghuraman S , Rege F , Reyes R , Rise C , Rogov P , Ross K , Ryan E , Settipalli S , Shea T , Sherpa N , Shi L , Shih D , Sparrow T , Spaulding J , Stalker J , Stange-Thomann N , Stavropoulos S , Stone C , Strader C , Tesfaye S , Thomson T , Thoulutsang Y , Thoulutsang D , Topham K , Topping I , Tsamla T , Vassiliev H , Vo A , Wangchuk T , Wangdi T , Weiand M , Wilkinson J , Wilson A , Yadav S , Young G , Yu Q , Zembek L , Zhong D , Zimmer A , Zwirko Z , Alvarez P , Brockman W , Butler J , Chin C , Grabherr M , Kleber M , Mauceli E , MacCallum I (- 405) Ref: Nature, 450 :203, 2007 : PubMed Abstract ESTHER: Clark_2007_Nature_450_203 PubMedSearch: Clark 2007 Nature 450 203 PubMedID: 17994087 Gene_locus related to this paper: droan-ACHE ,
droan-b3lx10 ,
droan-b3lx75 ,
droan-b3lxv7 ,
droan-b3ly87 ,
droan-b3lyh4 ,
droan-b3lyh5 ,
droan-b3lyh7 ,
droan-b3lyh9 ,
droan-b3lyi0 ,
droan-b3lyi2 ,
droan-b3lyi3 ,
droan-b3lyi4 ,
droan-b3lyj8 ,
droan-b3lyj9 ,
droan-b3lyx4 ,
droan-b3lyx5 ,
droan-b3lyx6 ,
droan-b3lyx7 ,
droan-b3lyx9 ,
droan-b3lz72 ,
droan-b3m1x3 ,
droan-b3m2d4 ,
droan-b3m3d9 ,
droan-b3m4e3 ,
droan-b3m5w1 ,
droan-b3m6i7 ,
droan-b3m7v2 ,
droan-b3m9a5 ,
droan-b3m9f4 ,
droan-b3m9p3 ,
droan-b3m254 ,
droan-b3m259 ,
droan-b3m260 ,
droan-b3m262 ,
droan-b3m524 ,
droan-b3m635 ,
droan-b3m845 ,
droan-b3m846 ,
droan-b3md01 ,
droan-b3mdh7 ,
droan-b3mdm6 ,
droan-b3mdw8 ,
droan-b3mee1 ,
droan-b3mf47 ,
droan-b3mf48 ,
droan-b3mg94 ,
droan-b3mgk2 ,
droan-b3mgn6 ,
droan-b3mii3 ,
droan-b3mjk2 ,
droan-b3mjk3 ,
droan-b3mjk4 ,
droan-b3mjk5 ,
droan-b3mjl2 ,
droan-b3mjl4 ,
droan-b3mjl7 ,
droan-b3mjl9 ,
droan-b3mjm8 ,
droan-b3mjm9 ,
droan-b3mjs6 ,
droan-b3mkr0 ,
droan-b3ml20 ,
droan-b3mly4 ,
droan-b3mly5 ,
droan-b3mly6 ,
droan-b3mmm8 ,
droan-b3mnb5 ,
droan-b3mny9 ,
droan-b3mtj5 ,
droan-b3muw4 ,
droan-b3muw8 ,
droan-b3n0e7 ,
droan-b3n2j7 ,
droan-b3n247 ,
droan-c5idb2 ,
droer-ACHE ,
droer-b3n5c7 ,
droer-b3n5d0 ,
droer-b3n5d8 ,
droer-b3n5d9 ,
droer-b3n5t7 ,
droer-b3n5y4 ,
droer-b3n7d2 ,
droer-b3n7d3 ,
droer-b3n7d4 ,
droer-b3n7k8 ,
droer-b3n8e4 ,
droer-b3n8f7 ,
droer-b3n8f8 ,
droer-b3n9e1 ,
droer-b3n319 ,
droer-b3n547 ,
droer-b3n549 ,
droer-b3n558 ,
droer-b3n560 ,
droer-b3n577 ,
droer-b3n612 ,
droer-b3nar5 ,
droer-b3nb91 ,
droer-b3nct9 ,
droer-b3nd53 ,
droer-b3ndh9 ,
droer-b3ndq8 ,
droer-b3ne66 ,
droer-b3ne67 ,
droer-b3ne97 ,
droer-b3nfk3 ,
droer-b3nfq9 ,
droer-b3nim7 ,
droer-b3nkn2 ,
droer-b3nm11 ,
droer-b3nmh4 ,
droer-b3nmy2 ,
droer-b3npx2 ,
droer-b3npx3 ,
droer-b3nq76 ,
droer-b3nqg9 ,
droer-b3nqm8 ,
droer-b3nr28 ,
droer-b3nrd3 ,
droer-b3nst4 ,
droer-b3nwa7 ,
droer-b3nyp5.1 ,
droer-b3nyp5.2 ,
droer-b3nyp6 ,
droer-b3nyp7 ,
droer-b3nyp8 ,
droer-b3nyp9 ,
droer-b3nyq3 ,
droer-b3nz06 ,
droer-b3nz14 ,
droer-b3nzj0 ,
droer-b3p0c0 ,
droer-b3p0c1 ,
droer-b3p0c2 ,
droer-b3p2x6 ,
droer-b3p2x7 ,
droer-b3p2x9 ,
droer-b3p2y1 ,
droer-b3p2y2 ,
droer-b3p6d4 ,
droer-b3p6d5 ,
droer-b3p6w3 ,
droer-b3p7b4 ,
droer-b3p7h9 ,
droer-b3p152 ,
droer-b3p486 ,
droer-b3p487 ,
droer-b3p488 ,
droer-b3p489 ,
droer-EST6 ,
droer-q670j5 ,
drogr-ACHE ,
drogr-b4iwp3 ,
drogr-b4iww3 ,
drogr-b4iwy3 ,
drogr-b4ixf7 ,
drogr-b4ixh4 ,
drogr-b4iyz5 ,
drogr-b4j2s2 ,
drogr-b4j2u8 ,
drogr-b4j3u1 ,
drogr-b4j3v3 ,
drogr-b4j4g7 ,
drogr-b4j4x9 ,
drogr-b4j6e6 ,
drogr-b4j9c9 ,
drogr-b4j9y4 ,
drogr-b4j156 ,
drogr-b4j384 ,
drogr-b4j605 ,
drogr-b4j685 ,
drogr-b4ja76 ,
drogr-b4jay5 ,
drogr-b4jcf0 ,
drogr-b4jcf1 ,
drogr-b4jdg6 ,
drogr-b4jdg7 ,
drogr-b4jdh6 ,
drogr-b4jdz1 ,
drogr-b4jdz2 ,
drogr-b4jdz4 ,
drogr-b4je66 ,
drogr-b4je79 ,
drogr-b4je82 ,
drogr-b4je88 ,
drogr-b4je89 ,
drogr-b4je90 ,
drogr-b4je91 ,
drogr-b4jf76 ,
drogr-b4jf79 ,
drogr-b4jf80 ,
drogr-b4jf81 ,
drogr-b4jf82 ,
drogr-b4jf83 ,
drogr-b4jf84 ,
drogr-b4jf85 ,
drogr-b4jf87 ,
drogr-b4jf91 ,
drogr-b4jf92 ,
drogr-b4jg66 ,
drogr-b4jgh0 ,
drogr-b4jgh1 ,
drogr-b4jgr9 ,
drogr-b4ji67 ,
drogr-b4jls2 ,
drogr-b4jnh9 ,
drogr-b4jpc6 ,
drogr-b4jpq3 ,
drogr-b4jpx9 ,
drogr-b4jql2 ,
drogr-b4jrh5 ,
drogr-b4jsb2 ,
drogr-b4jth3 ,
drogr-b4jti1 ,
drogr-b4jul5 ,
drogr-b4jur4 ,
drogr-b4jvh3 ,
drogr-b4jz00 ,
drogr-b4jz03 ,
drogr-b4jz04 ,
drogr-b4jz05 ,
drogr-b4jzh2 ,
drogr-b4k0u2 ,
drogr-b4k2r1 ,
drogr-b4k234 ,
drogr-b4k235 ,
drome-BEM46 ,
drome-CG3734 ,
drome-CG9953 ,
drome-CG11626 ,
drome-GH02439 ,
dromo-ACHE ,
dromo-b4k6a7 ,
dromo-b4k6a8 ,
dromo-b4k6q8 ,
dromo-b4k6q9 ,
dromo-b4k6r1 ,
dromo-b4k6r3 ,
dromo-b4k6r4 ,
dromo-b4k6r5 ,
dromo-b4k6r6 ,
dromo-b4k6r7 ,
dromo-b4k6r8 ,
dromo-b4k6r9 ,
dromo-b4k6s0 ,
dromo-b4k6s1 ,
dromo-b4k6s2 ,
dromo-b4k9c7 ,
dromo-b4k9d3 ,
dromo-b4k571 ,
dromo-b4k721 ,
dromo-b4ka74 ,
dromo-b4ka89 ,
dromo-b4kaj4 ,
dromo-b4kc20 ,
dromo-b4kcl2 ,
dromo-b4kcl3 ,
dromo-b4kd55.1 ,
dromo-b4kd55.2 ,
dromo-b4kd56 ,
dromo-b4kd57 ,
dromo-b4kde1 ,
dromo-b4kdg2 ,
dromo-b4kdh4 ,
dromo-b4kdh5 ,
dromo-b4kdh6 ,
dromo-A0A0Q9XDF2 ,
dromo-b4kdh8.1 ,
dromo-b4kdh8.2 ,
dromo-b4kg04 ,
dromo-b4kg05 ,
dromo-b4kg06 ,
dromo-b4kg16 ,
dromo-b4kg44 ,
dromo-b4kg90 ,
dromo-b4kh20 ,
dromo-b4kh21 ,
dromo-b4kht7 ,
dromo-b4kid3 ,
dromo-b4kik0 ,
dromo-b4kjx0 ,
dromo-b4kki1 ,
dromo-b4kkp6 ,
dromo-b4kkp8 ,
dromo-b4kkq8 ,
dromo-b4kkr0 ,
dromo-b4kkr3 ,
dromo-b4kkr4 ,
dromo-b4kks0 ,
dromo-b4kks1 ,
dromo-b4kks2 ,
dromo-b4kla1 ,
dromo-b4klv8 ,
dromo-b4knt4 ,
dromo-b4kp08 ,
dromo-b4kp16 ,
dromo-b4kqa6 ,
dromo-b4kqa7 ,
dromo-b4kqa8 ,
dromo-b4kqh1 ,
dromo-b4kst4 ,
dromo-b4ksy6 ,
dromo-b4kt84 ,
dromo-b4ktf5 ,
dromo-b4ktf6 ,
dromo-b4kvl3 ,
dromo-b4kvw2 ,
dromo-b4kwv4 ,
dromo-b4kwv5 ,
dromo-b4kxz6 ,
dromo-b4ky12 ,
dromo-b4ky36 ,
dromo-b4ky44 ,
dromo-b4kzu7 ,
dromo-b4l0n8 ,
dromo-b4l4u5 ,
dromo-b4l6l9 ,
dromo-b4l084 ,
drope-ACHE ,
drope-b4g3s6 ,
drope-b4g4p7 ,
drope-b4g6v4 ,
drope-b4g8m0 ,
drope-b4g8n6 ,
drope-b4g8n7 ,
drope-b4g9p2 ,
drope-b4g815 ,
drope-b4g816 ,
drope-b4gat7 ,
drope-b4gav5 ,
drope-b4gb05 ,
drope-b4gc08 ,
drope-b4gcr3 ,
drope-b4gdk2 ,
drope-b4gdl9 ,
drope-b4gdv9 ,
drope-b4gei8 ,
drope-b4gei9 ,
drope-b4gej0 ,
drope-b4ghz9 ,
drope-b4gj62 ,
drope-b4gj64 ,
drope-b4gj74 ,
drope-b4gkf4 ,
drope-b4gkv2 ,
drope-b4gky9 ,
drope-b4gl76 ,
drope-b4glf3 ,
drope-b4gmt3 ,
drope-b4gmt7 ,
drope-b4gmt9 ,
drope-b4gmu2 ,
drope-b4gmu3 ,
drope-b4gmu4 ,
drope-b4gmu5 ,
drope-b4gmu6 ,
drope-b4gmu7 ,
drope-b4gmv1 ,
drope-b4gn08 ,
drope-b4gpa7 ,
drope-b4gq13 ,
drope-b4grh7 ,
drope-b4gsf9 ,
drope-b4gsw4 ,
drope-b4gsw5 ,
drope-b4gsx2 ,
drope-b4gsx7 ,
drope-b4gsy6 ,
drope-b4gsy7 ,
drope-b4guj8 ,
drope-b4gw36 ,
drope-b4gzc2 ,
drope-b4gzc6 ,
drope-b4gzc7 ,
drope-b4h4p9 ,
drope-b4h5l3 ,
drope-b4h6a0 ,
drope-b4h6a8 ,
drope-b4h6a9 ,
drope-b4h6b0 ,
drope-b4h7m7 ,
drope-b4h462 ,
drope-b4h601 ,
drope-b4h602 ,
drope-b4hay1 ,
drope-b4hb18 ,
drope-est5a ,
drope-est5b ,
drope-est5c ,
drops-ACHE ,
drops-b5dhd2 ,
drops-b5dk96 ,
drops-b5dpe3 ,
drops-b5drp9 ,
drops-b5dwa7 ,
drops-b5dwa8 ,
drops-b5dz85 ,
drops-b5dz86 ,
drops-est5a ,
drops-est5b ,
drops-q29bq2 ,
drops-q29dd7 ,
drops-q29ew0 ,
drops-q291d5 ,
drops-q291e8 ,
drops-q293n1 ,
drops-q293n4 ,
drops-q293n5 ,
drops-q293n6 ,
drops-q294n6 ,
drops-q294n7 ,
drops-q294n9 ,
drops-q294p4 ,
drose-b4he97 ,
drose-b4hfu2 ,
drose-b4hg54 ,
drose-b4hga0 ,
drose-b4hgu9 ,
drose-b4hgv0 ,
drose-b4hgv3 ,
drose-b4hgv4 ,
drose-b4hhm8 ,
drose-b4hhs6 ,
drose-b4hie4 ,
drose-b4him9 ,
drose-b4hk63 ,
drose-b4hkj5 ,
drose-b4hr07 ,
drose-b4hr81 ,
drose-b4hre7 ,
drose-b4hs13 ,
drose-b4hsj9 ,
drose-b4hsk0 ,
drose-b4hsm8 ,
drose-b4hvr5 ,
drose-b4hwr7 ,
drose-b4hwr8 ,
drose-b4hwr9 ,
drose-b4hws6 ,
drose-b4hws7 ,
drose-b4hwt0 ,
drose-b4hwt2 ,
drose-b4hwu1 ,
drose-b4hwu2 ,
drose-b4hxs9 ,
drose-b4hxu4 ,
drose-b4hxz1 ,
drose-b4hyp8 ,
drose-b4hyp9 ,
drose-b4hyq0 ,
drose-b4hyz4 ,
drose-b4hyz5 ,
drose-b4i1k8 ,
drose-b4i2f3 ,
drose-b4i2w5 ,
drose-b4i4u3 ,
drose-b4i4u7 ,
drose-b4i4u9 ,
drose-b4i4v0 ,
drose-b4i4v1 ,
drose-b4i4v4 ,
drose-b4i4v5 ,
drose-b4i4v6 ,
drose-b4i4v7 ,
drose-b4i4v8 ,
drose-b4i4w0 ,
drose-b4i7s6 ,
drose-b4i133 ,
drose-b4i857 ,
drose-b4iam7 ,
drose-b4iam9 ,
drose-b4iaq6 ,
drose-b4icf6 ,
drose-b4icf7 ,
drose-b4id80 ,
drose-b4ifc5 ,
drose-b4ihv9 ,
drose-b4iie9 ,
drose-b4ilj8 ,
drose-b4in13 ,
drose-b4inj9 ,
drosi-ACHE ,
drosi-aes04a ,
drosi-b4nsh8 ,
drosi-b4q3d7 ,
drosi-b4q4w5 ,
drosi-b4q4y7 ,
drosi-b4q6h6 ,
drosi-b4q7u2 ,
drosi-b4q7u3 ,
drosi-b4q9c6 ,
drosi-b4q9c7 ,
drosi-b4q9d3 ,
drosi-b4q9d4 ,
drosi-b4q9r0 ,
drosi-b4q9r1 ,
drosi-b4q9r3 ,
drosi-b4q9s2 ,
drosi-b4q9s3 ,
drosi-b4q429 ,
drosi-b4q530 ,
drosi-b4q734 ,
drosi-b4q782 ,
drosi-b4q783 ,
drosi-b4q942 ,
drosi-b4qet1 ,
drosi-b4qfv6 ,
drosi-b4qge5 ,
drosi-b4qgh5 ,
drosi-b4qgs5 ,
drosi-b4qhf3 ,
drosi-b4qhf4 ,
drosi-b4qhi5 ,
drosi-b4qjr2 ,
drosi-b4qjr3 ,
drosi-b4qjv6 ,
drosi-b4qk23 ,
drosi-b4qk51 ,
drosi-b4qlt1 ,
drosi-b4qlz9 ,
drosi-b4qmn9 ,
drosi-b4qrq7 ,
drosi-b4qs01 ,
drosi-b4qs57 ,
drosi-b4qs82 ,
drosi-b4qs83 ,
drosi-b4qs84 ,
drosi-b4qs85 ,
drosi-b4qs86 ,
drosi-b4qsq1 ,
drosi-b4quk6 ,
drosi-b4qvg5 ,
drosi-b4qvg6 ,
drosi-b4qzn2 ,
drosi-b4qzn3 ,
drosi-b4qzn5 ,
drosi-b4qzn7 ,
drosi-b4qzn8 ,
drosi-b4qzp2 ,
drosi-b4qzp3 ,
drosi-b4qzp4 ,
drosi-b4qzp5 ,
drosi-b4qzp6 ,
drosi-b4qzp7 ,
drosi-b4r1a4 ,
drosi-b4r025 ,
drosi-b4r207 ,
drosi-b4r662 ,
drosi-este6 ,
drosi-q670k8 ,
drovi-ACHE ,
drovi-b4lev2 ,
drovi-b4lf33 ,
drovi-b4lf51 ,
drovi-b4lg54 ,
drovi-b4lg72 ,
drovi-b4lgc6 ,
drovi-b4lgd5 ,
drovi-b4lgg0 ,
drovi-b4lgk5 ,
drovi-b4lgn2 ,
drovi-b4lh17 ,
drovi-b4lh18 ,
drovi-b4lk43 ,
drovi-b4ll59 ,
drovi-b4ll60 ,
drovi-b4llm5 ,
drovi-b4lln3 ,
drovi-b4lmk4 ,
drovi-b4lmp0 ,
drovi-b4lnr4 ,
drovi-b4lp47 ,
drovi-b4lpd0 ,
drovi-b4lps0 ,
drovi-b4lqc6 ,
drovi-b4lr00 ,
drovi-b4lrp6 ,
drovi-b4lrw2 ,
drovi-b4lse7 ,
drovi-b4lse9 ,
drovi-b4lsf0 ,
drovi-b4lsn0 ,
drovi-b4lsq5 ,
drovi-b4lt32 ,
drovi-b4ltr1 ,
drovi-b4lui7 ,
drovi-b4lui9 ,
drovi-b4luj8 ,
drovi-b4luk0 ,
drovi-b4luk3 ,
drovi-b4luk8 ,
drovi-b4luk9 ,
drovi-b4lul0 ,
drovi-b4lve2 ,
drovi-b4lxi9 ,
drovi-b4lxj8 ,
drovi-b4lyf3 ,
drovi-b4lyq2 ,
drovi-b4lyq3 ,
drovi-b4lz07 ,
drovi-b4lz13 ,
drovi-b4lz14 ,
drovi-b4lz15 ,
drovi-b4m0j7 ,
drovi-b4m0s0 ,
drovi-b4m2b6 ,
drovi-b4m4h7 ,
drovi-b4m4h8 ,
drovi-b4m4i0 ,
drovi-b4m4i2 ,
drovi-b4m4i3.A ,
drovi-b4m4i3.B ,
drovi-b4m4i4 ,
drovi-b4m4i5 ,
drovi-b4m4i6 ,
drovi-b4m4i7 ,
drovi-b4m4i8 ,
drovi-b4m4i9 ,
drovi-b4m4j2 ,
drovi-b4m5a0 ,
drovi-b4m5a1 ,
drovi-b4m5a2 ,
drovi-b4m6b9 ,
drovi-b4m7k9 ,
drovi-b4m9g9 ,
drovi-b4m9h0 ,
drovi-b4m564 ,
drovi-b4m599 ,
drovi-b4m918 ,
drovi-b4mb87 ,
drovi-b4mc71 ,
drovi-b4mfa4 ,
drowi-ACHE ,
drowi-b4mjb9 ,
drowi-b4mkt7 ,
drowi-b4mlc1 ,
drowi-b4mp68 ,
drowi-b4mqe9 ,
drowi-b4mqf0.2 ,
drowi-b4mqf1 ,
drowi-b4mqf3 ,
drowi-b4mqf4 ,
drowi-b4mqf5 ,
drowi-b4mqq6 ,
drowi-b4mrd1 ,
drowi-b4mrk3 ,
drowi-b4mtl5 ,
drowi-b4mug2 ,
drowi-b4muj8 ,
drowi-b4mv18 ,
drowi-b4mw32 ,
drowi-b4mw85 ,
drowi-b4mwp2 ,
drowi-b4mwp6 ,
drowi-b4mwq5 ,
drowi-b4mwr0 ,
drowi-b4mwr8 ,
drowi-b4mwr9 ,
drowi-b4mwt1 ,
drowi-b4mwz7 ,
drowi-b4mxn5 ,
drowi-b4my54 ,
drowi-b4myg1 ,
drowi-b4myh5 ,
drowi-b4n0d4 ,
drowi-b4n1a7 ,
drowi-b4n1c8 ,
drowi-b4n3s9 ,
drowi-b4n3x7 ,
drowi-b4n4x9 ,
drowi-b4n4y0 ,
drowi-b4n6m1 ,
drowi-b4n6n0 ,
drowi-b4n6n7 ,
drowi-b4n6u6 ,
drowi-b4n7s6 ,
drowi-b4n7s7 ,
drowi-b4n7s8 ,
drowi-b4n899.1 ,
drowi-b4n8a1 ,
drowi-b4n8a2 ,
drowi-b4n8a3 ,
drowi-b4n8a4 ,
drowi-b4n8a9 ,
drowi-b4n023 ,
drowi-b4n075 ,
drowi-b4n543 ,
drowi-b4n888 ,
drowi-b4n889 ,
drowi-b4n891 ,
drowi-b4n893 ,
drowi-b4n895 ,
drowi-b4n897 ,
drowi-b4n898 ,
drowi-b4n899.2 ,
drowi-b4nae3 ,
drowi-b4ner8 ,
drowi-b4ng76 ,
drowi-b4nga7 ,
drowi-b4ngb5 ,
drowi-b4nhz9 ,
drowi-b4nj18 ,
drowi-b4nj19 ,
drowi-b4nja7 ,
drowi-b4nja8 ,
drowi-b4nja9 ,
drowi-b4njk8 ,
drowi-b4nkc8 ,
drowi-b4nky0 ,
drowi-b4nl36 ,
drowi-b4nm27 ,
drowi-b4nn59 ,
drowi-b4nnc1 ,
drowi-b4nng1 ,
drowi-b4nng2 ,
droya-ACHE ,
droya-aes04 ,
droya-b4itg2 ,
droya-b4itg6 ,
droya-b4itu9 ,
droya-b4iuv4 ,
droya-b4iuv5 ,
droya-b4nxe6 ,
droya-b4nxg5 ,
droya-b4nxg6 ,
droya-b4nxg8 ,
droya-b4nxw4 ,
droya-b4ny57 ,
droya-b4ny58 ,
droya-b4ny86 ,
droya-b4nzz8 ,
droya-b4p0b5 ,
droya-b4p0q9 ,
droya-b4p0r0 ,
droya-b4p0r7 ,
droya-b4p0r8 ,
droya-b4p0r9 ,
droya-b4p0s0 ,
droya-b4p0s2 ,
droya-b4p0t0 ,
droya-b4p0t1 ,
droya-b4p3h4 ,
droya-b4p3x8 ,
droya-b4p5g8 ,
droya-b4p6c9 ,
droya-b4p6l9 ,
droya-b4p6r1 ,
droya-b4p6r2 ,
droya-b4p7u4 ,
droya-b4p8w7 ,
droya-b4p023 ,
droya-b4p241 ,
droya-b4p774 ,
droya-b4pat9 ,
droya-b4pbl1 ,
droya-b4pd22 ,
droya-b4pd70 ,
droya-b4pdm8 ,
droya-b4pet9 ,
droya-b4pff9 ,
droya-b4pga7 ,
droya-b4pgu0 ,
droya-b4pig3 ,
droya-b4pjt8 ,
droya-b4pka2 ,
droya-b4plh2 ,
droya-b4pma3 ,
droya-b4pmv3 ,
droya-b4pmv4 ,
droya-b4pmv5 ,
droya-b4pn92 ,
droya-b4pp65 ,
droya-b4ppc5 ,
droya-b4ppc6 ,
droya-b4ppc7 ,
droya-b4ppc8 ,
droya-b4pq03 ,
droya-b4prg6B ,
droya-b4prg9 ,
droya-b4prh3 ,
droya-b4prh4 ,
droya-b4prh6 ,
droya-b4prh7 ,
droya-b4psz8 ,
droya-b4psz9 ,
droya-b4pv22 ,
droya-b4q0g5 ,
droya-b4q246 ,
droya-EST6 ,
droya-q71d76 ,
drowi-b4n7m9 ,
drope-b4gkk1 ,
droer-b3n5s3 ,
drose-b4i1w5 ,
drowi-a0a0q9x0t3 ,
drogr-b4jvm7 ,
dromo-b4ku70 ,
drovi-b4mcn9 ,
drovi-b4lty2 ,
drogr-b4jdu1 ,
drovi-a0a0q9wiq8 ,
dromo-b4kf70 ,
drosi-b2zi86 ,
droya-b4p2y4 ,
drose-b2zic5 ,
droer-b3n895 Abstract
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
Title: Principles of genome evolution in the Drosophila melanogaster species groupRanz JM , Maurin D , Chan YS , von Grotthuss M , Hillier LW , Roote J , Ashburner M , Bergman CM Ref: PLoS Biol, 5 :e152, 2007 : PubMed Abstract ESTHER: Ranz_2007_PLoS.Biol_5_E152 PubMedSearch: Ranz 2007 PLoS.Biol 5 E152 PubMedID: 17550304 Gene_locus related to this paper: drome-GH02439 ,
droya-ACHE ,
droya-aes04 ,
droya-b4itg2 ,
droya-b4itg6 ,
droya-b4itu9 ,
droya-b4iuv4 ,
droya-b4iuv5 ,
droya-b4nxe6 ,
droya-b4nxg5 ,
droya-b4nxg6 ,
droya-b4nxg8 ,
droya-b4ny57 ,
droya-b4ny58 ,
droya-b4ny86 ,
droya-b4nzz8 ,
droya-b4p3h4 ,
droya-b4p3x8 ,
droya-b4p5g8 ,
droya-b4p6l9 ,
droya-b4p6r1 ,
droya-b4p6r2 ,
droya-b4p8w7 ,
droya-b4p241 ,
droya-b4p774 ,
droya-b4pat9 ,
droya-b4pd22 ,
droya-b4pd70 ,
droya-b4pdm8 ,
droya-b4pff9 ,
droya-b4pga7 ,
droya-b4pgu0 ,
droya-b4pka2 ,
droya-b4plh2 ,
droya-b4pmv5 ,
droya-b4pn92 ,
droya-b4pp65 ,
droya-b4prg6B ,
droya-b4prg9 ,
droya-b4prh3 ,
droya-b4prh4 ,
droya-b4prh6 ,
droya-b4prh7 ,
droya-b4q0g5 ,
droya-EST6 ,
droya-b4p2y4 Abstract
That closely related species often differ by chromosomal inversions was discovered by Sturtevant and Plunkett in 1926. Our knowledge of how these inversions originate is still very limited, although a prevailing view is that they are facilitated by ectopic recombination events between inverted repetitive sequences. The availability of genome sequences of related species now allows us to study in detail the mechanisms that generate interspecific inversions. We have analyzed the breakpoint regions of the 29 inversions that differentiate the chromosomes of Drosophila melanogaster and two closely related species, D. simulans and D. yakuba, and reconstructed the molecular events that underlie their origin. Experimental and computational analysis revealed that the breakpoint regions of 59% of the inversions (17/29) are associated with inverted duplications of genes or other nonrepetitive sequences. In only two cases do we find evidence for inverted repetitive sequences in inversion breakpoints. We propose that the presence of inverted duplications associated with inversion breakpoint regions is the result of staggered breaks, either isochromatid or chromatid, and that this, rather than ectopic exchange between inverted repetitive sequences, is the prevalent mechanism for the generation of inversions in the melanogaster species group. Outgroup analysis also revealed evidence for widespread breakpoint recycling. Lastly, we have found that expression domains in D. melanogaster may be disrupted in D. yakuba, bringing into question their potential adaptive significance.
Title: The Evolution of an alpha-Esterase Pseudogene Inactivated in the Drosophila melanogaster LineageRobin GC , Russell RJ , Cutler DJ , Oakeshott JG Ref: Molecular Biology Evolution, 17 :563, 2000 : PubMed Abstract ESTHER: Robin_2000_Mol.Biol.Evol_17_563 PubMedSearch: Robin 2000 Mol.Biol.Evol 17 563 PubMedID: 10742048 Gene_locus related to this paper: drosi-aes04a ,
droya-aes04 Abstract
Previous analyses of the alpha-esterase cluster of Drosophila melanogaster revealed 10 active genes and the DmalphaE4a-Psi pseudogene. Here, we reconstruct the evolution of the pseudogene from the sequences of 12 alleles from widely scattered D. melanogaster populations and single alleles from Drosophila simulans and Drosophila yakuba. All of the DmalphaE4a-Psi alleles contain numerous inactivating mutations, suggesting that pseudogene alleles are fixed in natural populations. Several lines of evidence also suggest that DmalphaE4a is now evolving without selective constraint in the D. melanogaster lineage. There are three polymorphic indels which result in frameshifts; a key nucleotide of the intron splice acceptor is polymorphic; the neutral mutation parameter is the same for replacement and silent sites; one of the nonsilent polymorphisms results in a stop codon; only 1 of the 13 replacement polymorphisms is biochemically conservative; residues that are conserved among active esterases have different states in DmalphaE4a-Psi; and there are about half as many transitional polymorphisms as transversional ones. In contrast, the D. simulans and D. yakuba orthologs DsalphaE4a and DyalphaE4a do not have the inactivating mutations of DmalphaE4a-Psi and appear to be evolving under the purifying selection typical of protein- encoding genes. For instance, there have been more substitutions in the introns than in the exons, and more in silent sites than in replacement sites. Furthermore, most of the amino acid substitutions that have occurred between DyalphaE4a and DsalphaE4a are located in sites that typically vary among active alpha-esterases rather than those that are usually conserved. We argue that the original alphaE4a gene had a function which it has lost since the divergence of the D. melanogaster and D. simulans lineages.
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