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Gene_locus Report for: hetga-g5aua1

Heterocephalus glaber (Naked mole rat). Phospholipase A1 member A isoform 1

Relationship
Family|Phospholipase
Block| L
Position in NCBI Life Tree|Heterocephalus glaber
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Hystricomorpha: N E > Bathyergidae: N E > Heterocephalus: N E > Heterocephalus glaber: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
3 Genbank : JH166963, GEBF01002793, XP_004835718.1
1 UniProt : G5AUA1
1 UniProt : G5AUA1
1 Interpro : G5AUA1
1 Prodom : G5AUA1
1 Pfam : G5AUA1
1 PIRSF : G5AUA1
1 SUPERFAM : G5AUA1
Sequence
Graphical view for this peptide sequence: hetga-g5aua1
Colored MSA for Phospholipase (raw)
MPWSCWERSFWLWGLLLWLSTRSSGDAPAAPQPKCTDFQNANPFRGTNLK
VQFLLFIPLDPGCGQLLGESSDIQKSGFNATLGTKLIIHGFRALGTKPSW
IDAFIRALLRAADANVIAVDWVYGSTAVYYSAVDNVVKLSLEISRFLRKL
LDLGVSESSIHIIGVSLGAHVGGMVGHFFKGQLGRITGLDPAGPEYTRAS
LEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPLFIH
AGYSYLICDHMRAVHLYISALENSCPLMAFPCANYRAFLAGHCLDCFNPF
LLSCPRIGLVEQGGVQIEPLPKEVRVYLQTTPKAPYCVHHNLVEFYLQEA
RKKDTSIEISFVSTNVTSSVKITIARQQLQGKGILAHPNLPCQINQVVFK
LQASSRVWKKHRTIVGKFCTALLPVKDSKKTVCLPEPVNLQESGSVFHDW
KISCV
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MPWSCWERSFWLWGLLLWLSTRSSGDAPAAPQPKCTDFQNANPFRGTNLK
VQFLLFIPLDPGCGQLLGESSDIQKSGFNATLGTKLIIHGFRALGTKPSW
IDAFIRALLRAADANVIAVDWVYGSTAVYYSAVDNVVKLSLEISRFLRKL
LDLGVSESSIHIIGVSLGAHVGGMVGHFFKGQLGRITGLDPAGPEYTRAS
LEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPLFIH
AGYSYLICDHMRAVHLYISALENSCPLMAFPCANYRAFLAGHCLDCFNPF
LLSCPRIGLVEQGGVQIEPLPKEVRVYLQTTPKAPYCVHHNLVEFYLQEA
RKKDTSIEISFVSTNVTSSVKITIARQQLQGKGILAHPNLPCQINQVVFK
LQASSRVWKKHRTIVGKFCTALLPVKDSKKTVCLPEPVNLQESGSVFHDW
KISCV


Reference
    Title: Genome sequencing reveals insights into physiology and longevity of the naked mole rat
    Kim EB, Fang X, Fushan AA, Huang Z, Lobanov AV, Han L, Marino SM, Sun X, Turanov AA and Gladyshev VN <26 more author(s)>
    Ref: Nature, 479:223, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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