lache-pepx

Lactobacillus helveticus (x-prolyl-dipeptidyl aminopeptidase) (x-pdap) pepx (EC 3.4.14.5)

Comment

Other strains: Lactobacillus helveticus (H10\; DPC 4571\; DSM 20075), Lactobacillus amylovorus (GRL 1118\; GRL 1112), Lactobacillus acidophilus (30SC\; ATCC 4796\; ATCC 700396 \/ NCK56 \/ N2 \/ NCFM)

Relationship

Family : Lactobacillus_peptidase

Block : X

Position in NCBI Life Tree : Lactobacillus helveticus

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Sequence

Peptide

MKYNQYAYVE TDFQQQVKEL IDINFLPKNY QVWDFGSLLA KLVKNAIAEA KTDAAKNAKL AEFAVSDHQT LADFLKEKPT EIGTKQFYNV ALQLLGYHVH YDYDFADPTG FMQRNALPFL QDISDNQKLI SAFYRLLNTR AKNGQILLDV MAGKGYFTQF WGQNKFKFFN GKSIPVFDTN KVIREVVYVE TDLDTDHDGK SDLIQVTVFR PEETNKGLKV PALYTASPYF GGIIANEKRN HNVDENLSDS TEWNDPQYVH SPIVKAEKPD GSSRPATEEA VHKSSYPLNE YMLARGFASV FAGAIGTRGS DGVRITGAPE ETESAAAVIE WLHGDRVAYT DRTRTVRTTA DWCNGNIGMT GRSYLGTLQI AIATTGVKGL KTVVSEAAIS SWYDYYREHG SVIAPEACQG EDLDLLAETC QSNLWDAGSY LKIKPEYDKM QKQLREKEDR NTGQYSDFWE AGNYRHHADG IKCSWISVHG LNDWNVKPKN VYKIWQLVKK MPMKHHLFLH QGPHYNMNNL VSIDFTDLMN LWFVHELLGI ENNAYNQWPT VMIQDNLQAD KWHEEPDWSN DLGQEKIYYP TDEGELFQDG NGKAQKSFTD VGGIEFKKAG ISESDWQYKF ICGDEKWAKP SLRFETDEFT HPTTIVGRPE VKVRVSASLP KGEISVALVE LGERQRLTAT PKFLMHGGQE LGYRFGTDTL QEFVPDKKTK AKLITKAHMN LQNFKDMKKP EAIDADKFYD LDFLLQPTYY TIPSGSKLAL IIYSTDQGMT KRPLEDETYT IDLANTEIKF YEK

References

Title : Elucidating the Role of a Calcium-Binding Loop in an x-Prolyl Aminodipeptidase from Lb. helveticus - Ryder_2023_ACS.Omega_8_35410
Author(s) : Ryder S , Pedigo J , Ojennus DD
Ref : ACS Omega , 8 :35410 , 2023
Abstract : Ryder_2023_ACS.Omega_8_35410
ESTHER : Ryder_2023_ACS.Omega_8_35410
PubMedSearch : Ryder_2023_ACS.Omega_8_35410
PubMedID: 37779945
Gene_locus related to this paper: lache-pepx

Title : Structural characterization of a prolyl aminodipeptidase (PepX) from Lactobacillus helveticus - Ojennus_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_625
Author(s) : Ojennus DD , Bratt NJ , Jones KL , Juers DH
Ref : Acta Crystallographica F Struct Biol Commun , 75 :625 , 2019
Abstract : Ojennus_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_625
ESTHER : Ojennus_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_625
PubMedSearch : Ojennus_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_625
PubMedID: 31584010
Gene_locus related to this paper: lache-pepx

Title : Characterization of the recombinant exopeptidases PepX and PepN from Lactobacillus helveticus ATCC 12046 important for food protein hydrolysis - Stressler_2013_PLoS.One_8_e70055
Author(s) : Stressler T , Eisele T , Schlayer M , Lutz-Wahl S , Fischer L
Ref : PLoS ONE , 8 :e70055 , 2013
Abstract : Stressler_2013_PLoS.One_8_e70055
ESTHER : Stressler_2013_PLoS.One_8_e70055
PubMedSearch : Stressler_2013_PLoS.One_8_e70055
PubMedID: 23894590
Gene_locus related to this paper: lache-pepx

Title : Complete genome sequence of Lactobacillus helveticus H10 - Zhao_2011_J.Bacteriol_193_2666
Author(s) : Zhao W , Chen Y , Sun Z , Wang J , Zhou Z , Sun T , Wang L , Chen W , Zhang H
Ref : Journal of Bacteriology , 193 :2666 , 2011
Abstract : Zhao_2011_J.Bacteriol_193_2666
ESTHER : Zhao_2011_J.Bacteriol_193_2666
PubMedSearch : Zhao_2011_J.Bacteriol_193_2666
PubMedID: 21398542
Gene_locus related to this paper: lach4-a8yw60 , lache-pepx , lache-pip , lache-prolinase

Title : Genome sequence of Lactobacillus amylovorus GRL1112 - Kant_2011_J.Bacteriol_193_789
Author(s) : Kant R , Paulin L , Alatalo E , de Vos WM , Palva A
Ref : Journal of Bacteriology , 193 :789 , 2011
Abstract : Kant_2011_J.Bacteriol_193_789
ESTHER : Kant_2011_J.Bacteriol_193_789
PubMedSearch : Kant_2011_J.Bacteriol_193_789
PubMedID: 21131492
Gene_locus related to this paper: lache-pepx , lache-prolinase , lacar-e4sin9 , lacar-e4sjn9

Title : Genome sequence of Lactobacillus amylovorus GRL1118, isolated from pig ileum - Kant_2011_J.Bacteriol_193_3147
Author(s) : Kant R , Paulin L , Alatalo E , de Vos WM , Palva A
Ref : Journal of Bacteriology , 193 :3147 , 2011
Abstract : Kant_2011_J.Bacteriol_193_3147
ESTHER : Kant_2011_J.Bacteriol_193_3147
PubMedSearch : Kant_2011_J.Bacteriol_193_3147
PubMedID: 21478337
Gene_locus related to this paper: lache-pepx , lache-prolinase

Title : Complete genome sequencing of Lactobacillus acidophilus 30SC, isolated from swine intestine - Oh_2011_J.Bacteriol_193_2882
Author(s) : Oh S , Roh H , Ko HJ , Kim S , Kim KH , Lee SE , Chang IS , Choi IG
Ref : Journal of Bacteriology , 193 :2882 , 2011
Abstract : Oh_2011_J.Bacteriol_193_2882
ESTHER : Oh_2011_J.Bacteriol_193_2882
PubMedSearch : Oh_2011_J.Bacteriol_193_2882
PubMedID: 21478365
Gene_locus related to this paper: lache-pepx , lache-prolinase

Title : Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion - Callanan_2008_J.Bacteriol_190_727
Author(s) : Callanan M , Kaleta P , O'Callaghan J , O'Sullivan O , Jordan K , McAuliffe O , Sangrador-Vegas A , Slattery L , Fitzgerald GF , Beresford T , Ross RP
Ref : Journal of Bacteriology , 190 :727 , 2008
Abstract : Callanan_2008_J.Bacteriol_190_727
ESTHER : Callanan_2008_J.Bacteriol_190_727
PubMedSearch : Callanan_2008_J.Bacteriol_190_727
PubMedID: 17993529
Gene_locus related to this paper: lach4-a8yut9 , lach4-a8yw60 , lache-a4zgw4 , lache-pepx , lache-pip , lache-prolinase

Title : Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM - Altermann_2005_Proc.Natl.Acad.Sci.U.S.A_102_3906
Author(s) : Altermann E , Russell WM , Azcarate-Peril MA , Barrangou R , Buck BL , McAuliffe O , Souther N , Dobson A , Duong T , Callanan M , Lick S , Hamrick A , Cano R , Klaenhammer TR
Ref : Proc Natl Acad Sci U S A , 102 :3906 , 2005
Abstract : Altermann_2005_Proc.Natl.Acad.Sci.U.S.A_102_3906
ESTHER : Altermann_2005_Proc.Natl.Acad.Sci.U.S.A_102_3906
PubMedSearch : Altermann_2005_Proc.Natl.Acad.Sci.U.S.A_102_3906
PubMedID: 15671160
Gene_locus related to this paper: lacac-q5fhs3 , lacac-q5fhw5 , lacac-q5fi30 , lacac-q5fin2 , lacac-q5fj74 , lacac-q5fje2 , lacac-q5fje7 , lacac-q5fk68 , lacac-q5fkd4 , lacac-q5fkk4 , lacac-q5fkq4 , lacac-q5flb5 , lacac-q5flg1 , lacac-q5fmp9 , lacac-q5fmq3 , lacac-pip , lacac-q5fmz8 , lache-pepx , lache-prolinase

Title : Peptidase activity in various species of dairy thermophilic lactobacilli - Gatti_2004_J.Appl.Microbiol_96_223
Author(s) : Gatti M , Fornasari ME , Lazzi C , Mucchetti G , Neviani E
Ref : J Appl Microbiol , 96 :223 , 2004
Abstract : Gatti_2004_J.Appl.Microbiol_96_223
ESTHER : Gatti_2004_J.Appl.Microbiol_96_223
PubMedSearch : Gatti_2004_J.Appl.Microbiol_96_223
PubMedID: 14723683
Gene_locus related to this paper: lache-pepx

Title : Impaired growth rates in milk of Lactobacillus helveticus peptidase mutants can be overcome by use of amino acid supplements - Christensen_2003_J.Bacteriol_185_3297
Author(s) : Christensen JE , Steele JL
Ref : Journal of Bacteriology , 185 :3297 , 2003
Abstract : Christensen_2003_J.Bacteriol_185_3297
ESTHER : Christensen_2003_J.Bacteriol_185_3297
PubMedSearch : Christensen_2003_J.Bacteriol_185_3297
PubMedID: 12754227
Gene_locus related to this paper: lache-pepx

Title : Cloning of the pepX gene of Lactobacillus helveticus IF03809 encoding salt-tolerant X-prolyl dipeptidyl aminopeptidase and characterization of the enzyme - Kimura_2002_J.Biosci.Bioeng_93_589
Author(s) : Kimura K , Nagasawa A , Fujii M , Itoh Y
Ref : J Biosci Bioeng , 93 :589 , 2002
Abstract : Kimura_2002_J.Biosci.Bioeng_93_589
ESTHER : Kimura_2002_J.Biosci.Bioeng_93_589
PubMedSearch : Kimura_2002_J.Biosci.Bioeng_93_589
PubMedID: 16233254
Gene_locus related to this paper: lache-pepx

Title : DNA sequence analysis, expression, distribution, and physiological role of the Xaa-prolyldipeptidyl aminopeptidase gene from Lactobacillus helveticus CNRZ32 - Yuksel_1996_Appl.Microbiol.Biotechnol_44_766
Author(s) : Yuksel GU , Steele JL
Ref : Applied Microbiology & Biotechnology , 44 :766 , 1996
Abstract : Yuksel_1996_Appl.Microbiol.Biotechnol_44_766
ESTHER : Yuksel_1996_Appl.Microbiol.Biotechnol_44_766
PubMedSearch : Yuksel_1996_Appl.Microbiol.Biotechnol_44_766
PubMedID: 8867635
Gene_locus related to this paper: lache-pepx

Title : An X-prolyl dipeptidyl aminopeptidase (pepX) gene from Lactobacillus helveticus - Vesanto_1995_Microbiology_141 ( Pt 12)_3067
Author(s) : Vesanto E , Savijoki K , Rantanen T , Steele JL , Palva A
Ref : Microbiology , 141 ( Pt 12) :3067 , 1995
Abstract : Vesanto_1995_Microbiology_141 ( Pt 12)_3067
ESTHER : Vesanto_1995_Microbiology_141 ( Pt 12)_3067
PubMedSearch : Vesanto_1995_Microbiology_141 ( Pt 12)_3067
PubMedID: 8574400
Gene_locus related to this paper: lache-pepx