Gene_locus Report for: legpl-q5wur2 Legionella pneumophila (strain Lens) hypothetical protein
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Bacteria: N E > Proteobacteria: N E > Gammaproteobacteria: N E > Legionellales: N E > Legionellaceae: N E > Legionella: N E > Legionella pneumophila: N E 6_AlphaBeta_hydrolase :
legpa-q5ws59 Legionella pneumophila (strain Paris); Legionella hackeliae hypothetical protein ,
legpa-q5x2c0 Legionella pneumophila (strain Paris) hypothetical protein ,
legpa-q5x2s1 Legionella pneumophila (strain Paris) hypothetical protein ,
legpa-q5x5b2 Legionella pneumophila (strain Paris) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) (strain Lens) hypothetical protein ,
legpa-q5x5z2 Legionella pneumophila (strain Paris) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) hypothetical protein ,
legpa-q5x8e6 Legionella pneumophila (strain Paris) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) (strain Lens) hypothetical protein ,
legpa-q5x405 Legionella pneumophila (strain Paris) (strain Corby) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) (strain Lens) hypothetical protein ,
legpc-a5iar0 Legionella pneumophila (strains Corby; Lens; Paris; subsp. pneumophila str. Philadelphia 1 ATCC 33152 / DSM 7513) Probable hydrolase ,
legpl-q5wvw9 Legionella pneumophila (strain Lens) (strain Paris) subsp. pneumophila (strain Philadelphia) hypothetical protein ,
legpn-Q8KU34 Legionella pneumophila putative lipase lipa (strain paris philadelphia lens) .
A85-IroE-IroD-Fes-Yiel :
legpa-q5ws33 Legionella pneumophila (strain Paris); Legionella hackeliae hypothetical protein ,
legpa-q5ws67 Legionella pneumophila (strain Paris); Legionella hackeliae hypothetical protein .
abh_upf0017 :
legpa-q5x4t1 Legionella pneumophila hypothetical protein .
ACPH_Peptidase_S9 :
legpa-q5x4r4 Legionella pneumophila (strain Paris) (strain Lens) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 )acylaminoacyl peptidase .
AlphaBeta_hydrolase :
legph-q5zv00 Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) (strain Lens) sidb putative substrate of the dot/icm system .
BioH :
legpa-q5x590 Legionella pneumophila (strain Paris) (strain Lens) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 ) (strain Corby) biotin biosynthesis protein bioh .
CarbLipBact_2 :
legpl-q5wsw9 Legionella pneumophila complete genome .
Chlorophyllase :
legpa-q5ws68 Legionella pneumophila (strain Paris); Legionella hackeliae hypothetical protein .
Dienelactone_hydrolase :
legpl-q5wtd3 Legionella pneumophila (strain Lens) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) egionella pneumophila (strain Paris) hypothetical protein ,
legpn-SBPA Legionella pneumophila sbpa Legionella pneumophila (strain Paris)Legionella pneumophila subsp. pneumophila (strain Philadelphia) .
DLH-S :
legpc-a5iew3 Legionella pneumophila (strains Corby; serogroup 1 (strain 2300/99 Alcoy)) Putative uncharacterized protein .
Duf_676 :
legpa-q5x611 Legionella pneumophila (strain Paris) hypothetical protein .
Duf_3141 :
legpa-q5x3d6 Legionella pneumophila (strain Paris) (strain Corby) (strain Lens) (strain Philadelphia 1 ATCC 33152 / DSM 7513) Putative uncharacterized protein ,
legpn-Q8RNQ1 Legionella pneumophila (and subsp. pneumophila (strain Philadelphia 1 ATCC 33152 / DSM 7513) (strain Paris) (strain Corby) hypothetical protein .
Duf_3530 :
legpl-q5wua5 Legionella pneumophila Putative uncharacterized protein .
Est-OsmC :
legpa-q5x8m4 Legionella pneumophila Legionella pneumophila subsp. pneumophila esterase often found in n-term of an OsmC/Ohr family domain but not here .
Fungal-Bact_LIP :
legph-q5zwi2 .
Hormone-sensitive_lipase_like :
legpa-q5x424 Legionella pneumophila Lipase .
lpg2422 :
legph-q5zsu4 .
LYsophospholipase_carboxylesterase :
legpa-q5x819 Legionella pneumophila (strain Paris) (strain Lens) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) hypothetical protein .
PhaC_cen_dom :
legpa-q5x2r4 Legionella pneumophila, Polyhydroxyalkanoic synthase phbC ,
legpa-q5x3j6 Legionella pneumophila (strain Paris) hypothetical protein ,
legpa-q5x322 Legionella pneumophila PHA synthase .
PHA_synth_I :
legpa-q5x7f5 Legionella pneumophila (strain Paris) (strain Lens) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) hypothetical protein .
PlaB :
legpn-i7i328 .
Proline_iminopeptidase :
legpa-q5x473 Legionella pneumophila hypothetical protein .
Thioesterase :
legpa-q5x3a5 Legionella pneumophila (strain Paris) Legionella pneumophila subsp. pneumophila (strain Philadelphia 1) hypothetical protein Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: legpl-q5wur2 Colored MSA for Thioesterase (raw)
KQHPFFFCHPASGMVYCFDDLASFWDYPISLYGLQDPSVSSGKLIFESLS
SMAKAYTQAIKKVQPHGPYFLVGYSFGGSLMHEVAHLLAQQNERIGLLAM
IDSWCTFSSKQKSKNHFIEAYLSKELQASRNLADLAWERMELLLNHKPTK
INQDMVLFKATDLNQDYLDIDDPKNGWGQYNLGQIICHTIEANHDTIIRQ
GYQFIAQKLIEYRDIE
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
K Q H P F F F C H P A S G M V Y C F D D L A S F W D Y P I S L Y G L Q D P S V S S G K L I F E S L S S M A K A Y T Q A I K K V Q P H G P Y F L V G Y S F G G S L M H E V A H L L A Q Q N E R I G L L A M I D S W C T F S S K Q K S K N H F I E A Y L S K E L Q A S R N L A D L A W E R M E L L L N H K P T K I N Q D M V L F K A T D L N Q D Y L D I D D P K N G W G Q Y N L G Q I I C H T I E A N H D T I I R Q G Y Q F I A Q K L I E Y R D I E
Reference
Title: Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticityCazalet C , Rusniok C , Bruggemann H , Zidane N , Magnier A , Ma L , Tichit M , Jarraud S , Bouchier C and Buchrieser C <4 more author(s)> Cazalet C , Rusniok C , Bruggemann H , Zidane N , Magnier A , Ma L , Tichit M , Jarraud S , Bouchier C , Vandenesch F , Kunst F , Etienne J , Glaser P , Buchrieser C (- 4) Ref: Nat Genet, 36 :1165, 2004 : PubMed Abstract ESTHER: Cazalet_2004_Nat.Genet_36_1165 PubMedSearch: Cazalet 2004 Nat.Genet 36 1165 PubMedID: 15467720 Gene_locus related to this paper: legph-q5zsu4 ,
legpa-q5ws33 ,
legpa-q5ws59 ,
legpa-q5ws67 ,
legpa-q5ws68 ,
legpa-q5x2c0 ,
legpa-q5x2r4 ,
legpa-q5x2s1 ,
legpa-q5x3a5 ,
legpa-q5x3d6 ,
legpa-q5x3j6 ,
legpa-q5x4r4 ,
legpa-q5x4t1 ,
legpa-q5x5b2 ,
legpa-q5x5z2 ,
legpa-q5x7f5 ,
legpa-q5x8e6 ,
legpa-q5x8m4 ,
legpa-q5x322 ,
legpa-q5x405 ,
legpa-q5x424 ,
legpa-q5x473 ,
legpa-q5x590 ,
legpa-q5x611 ,
legpa-q5x819 ,
legpc-a5iar0 ,
legph-q5zv00 ,
legph-q5zwi2 ,
legpl-q5wtd3 ,
legpl-q5wua5 ,
legpl-q5wur2 ,
legpl-q5wvw9 ,
legpn-Q8KU34 ,
legpn-Q8RNQ1 ,
legpn-SBPA ,
legpn-i7i328 ,
legpl-q5wsw9 Abstract
Legionella pneumophila, the causative agent of Legionnaires' disease, replicates as an intracellular parasite of amoebae and persists in the environment as a free-living microbe. Here we have analyzed the complete genome sequences of L. pneumophila Paris (3,503,610 bp, 3,077 genes), an endemic strain that is predominant in France, and Lens (3,345,687 bp, 2,932 genes), an epidemic strain responsible for a major outbreak of disease in France. The L. pneumophila genomes show marked plasticity, with three different plasmids and with about 13% of the sequence differing between the two strains. Only strain Paris contains a type V secretion system, and its Lvh type IV secretion system is encoded by a 36-kb region that is either carried on a multicopy plasmid or integrated into the chromosome. Genetic mobility may enhance the versatility of L. pneumophila. Numerous genes encode eukaryotic-like proteins or motifs that are predicted to modulate host cell functions to the pathogen's advantage. The genome thus reflects the history and lifestyle of L. pneumophila, a human pathogen of macrophages that coevolved with fresh-water amoebae.
Other Papers
Legionella pneumophila Putative uncharacterized protein