(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Eukaryota: NE > Opisthokonta: NE > Metazoa: NE > Eumetazoa: NE > Bilateria: NE > Protostomia: NE > Ecdysozoa: NE > Panarthropoda: NE > Arthropoda: NE > Mandibulata: NE > Pancrustacea: NE > Hexapoda: NE > Insecta: NE > Dicondylia: NE > Pterygota: NE > Neoptera: NE > Holometabola: NE > Diptera: NE > Brachycera: NE > Muscomorpha: NE > Eremoneura: NE > Cyclorrhapha: NE > Schizophora: NE > Calyptratae: NE > Oestroidea: NE > Calliphoridae: NE > Luciliinae: NE > Lucilia: NE > Lucilia cuprina: NE
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA AIDPSTIEFVNFSISLQETTAWKTLTSHPNSLVQLLPSRAMRVVQEVVRS FRKDTQVVVTTSAGKVRGRFQKYRSGERGGYYSFKGIRYGQAPVGDRRFR AAEPEKSWSGIRDASREGNSCPHKNMILDTFKGNEDCLFINVFTAKLPKG EYNPQFPVMVWLHGGGYSFGSGNTFLYGPDYLVAENVVLVTLNYRLGPLG FLTAGPDAPGNQGLKDQILALKWVRDNIAAFGGDPNQVTVFGESAGASSV QMLLLSPLAKGLFQRAISESGSALNPWSMGENSVARAARLAANLGYVGAN NTEDILEFLRRAPAMKLVEAAPTTLTEEDFRNNIGLPFVPVVEGYWNKEG EKNVYYEAPFITESPQESYRKQKFHKNIPYLTGYNTHEAMLFIRRLRKNP QLLQIIENDFERLVPHDLNVTDQRPRVSRDIRQFYLGSKQVGIESVDEMI ALLTDLMFLQGIRRTARNHAKYGNAPVYMYRFSFDGALGLYKRMLGLQRP GVCHGDEMGYLFKFGFFNLSLDPKSMEVLVKNRMVRMWTNFAKYGNPTPQ HIDDNLLTTTWQPINPNDVMQNLNYMDITTNLEMKTNPETERQQFWDYMY EHYNGNAM
Lucilia cuprina is a parasitic fly of major economic importance worldwide. Larvae of this fly invade their animal host, feed on tissues and excretions and progressively cause severe skin disease (myiasis). Here we report the sequence and annotation of the 458-megabase draft genome of Lucilia cuprina. Analyses of this genome and the 14,544 predicted protein-encoding genes provide unique insights into the fly's molecular biology, interactions with the host animal and insecticide resistance. These insights have broad implications for designing new methods for the prevention and control of myiasis.