Gene_locus Report for: macmu-f7ai42 Macaca mulatta (Rhesus macaque) Uncharacterized protein
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Primates: N E > Haplorrhini: N E > Simiiformes: N E > Catarrhini: N E > Cercopithecoidea: N E > Cercopithecidae: N E > Cercopithecinae: N E > Macaca: N E > Macaca mulatta: N E ABHD6-Lip :
macmu-f7hir7 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
ABHD8 :
macmu-i2cyv7 Macaca mulatta (Rhesus macaque). Abhydrolase domain-containing protein 8 .
ABHD10 :
macmu-h9zaw9 Macaca mulatta (Rhesus macaque). Abhydrolase domain-containing protein 10, mitochondrial .
ABHD12-PHARC :
macmu-f7flv1 Macaca mulatta (Rhesus macaque) Uncharacterized protein ,
macmu-a0a1d5rbr3 Macaca mulatta (Rhesus macaque). Uncharacterized protein .
ABHD13-BEM46 :
macmu-f7h550 Macaca mulatta (Rhesus macaque). Abhydrolase domain-containing protein 13 ,
macmu-a0a1d5q9w1 Macaca mulatta (Rhesus macaque). Hydrolase_4 domain-containing protein .
ABHD16 :
macmu-f6qwx1 Macaca mulatta (Rhesus macaque). HLA-B-associated transcript 5 ,
macmu-f7h4t2 Macaca mulatta (Rhesus macaque). Uncharacterized protein .
ACHE :
macmu-ACHE Macaca mulatta (Rhesus macaque) acetylcholinesterase gene complete cds .
Arb2_FAM172A :
macmu-i0fgb6 Macaca mulatta (Rhesus macaque). Uncharacterized protein .
Arylacetamide_deacetylase :
macmu-nceh1 Macaca mulatta (Rhesus macaque) NCEH1 Arylacetamide deacetylase-like 1 ,
macmu-a0a1d5q4k5 Macaca mulatta (Rhesus macaque). Uncharacterized protein .
BCHE :
macmu-BCHE Macaca mulatta butyrylcholinesterase .
Carboxypeptidase_S10 :
macmu-f6rbn1 Macaca mulatta (Rhesus macaque); Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) Carboxypeptidase CTSA ,
macmu-f6wtx1 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
Carb_B_Chordata :
macmu-f6unj2 Macaca mulatta (Rhesus macaque) Uncharacterized protein ,
macmu-f7aa58 Macaca mulatta (Rhesus macaque) Uncharacterized protein ,
macmu-f7aim4 Macaca mulatta (Rhesus macaque) Epididymis-specific carboxylesterase ,
macmu-g7npb8 Macaca mulatta (Rhesus macaque) Liver carboxylesterase 1 isoform a ,
macmu-g7nq39 Macaca mulatta (Rhesus macaque) Putative uncharacterized protein ,
macmu-CES2 Macaca mulatta (Rhesus macaque). Carboxylic ester hydrolase .
Cholesterol_esterase :
macmu-f7buk8 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
CIB-CCG1-interacting-factor-B :
macmu-f7cnr2 Macaca mulatta (Rhesus macaque) Uncharacterized protein ,
macmu-f7cu68 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
CMBL :
macmu-f7gkb9 Macaca mulatta (Rhesus macaque). Carboxymethylenebutenolidase-like protein .
DPP4N_Peptidase_S9 :
macmu-q2mjp3 Macaca mulatta (Rhesus macaque) dipeptidylpeptidase IV (EC 3.4.14.5) .
Hepatic_Lipase :
macmu-g7mxj6 Macaca mulatta (Rhesus macaque). Hepatic triacylglycerol lipase .
Kynurenine-formamidase :
macmu-f7ba84 Macaca mulatta (Rhesus macaque). N-formylkynurenine formamidase .
Lipase_3 :
macmu-i2cu80 Macaca mulatta (Rhesus macaque). Sn1-specific diacylglycerol lipase alpha .
Lipoprotein_Lipase :
macmu-a0a1d5rh04 Macaca mulatta (Rhesus macaque). Lipase G, endothelial type ,
macmu-h9fud6 Macaca mulatta (Rhesus macaque). Lipoprotein lipase .
Maspardin-ACP33-SPG21_like :
macmu-f7ggk1 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
Monoglyceridelipase_lysophospholip :
macmu-h9er02 Macaca mulatta (Rhesus macaque). Monoglyceride lipase .
Ndr_family :
macmu-g7n4x3 Macaca mulatta (Rhesus macaque) Protein NDRG3 Putative uncharacterized protein ,
macmu-i2cy02 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
Neuroligin :
macmu-3neur Macaca mulatta (Rhesus macaque) Neuroligin-3 isoform 1,2,3 ,
macmu-f6rul6 Macaca mulatta (Rhesus macaque) Uncharacterized protein ,
macmu-f6sz31 Macaca mulatta (Rhesus macaque) neuroligin 2 ,
macmu-f7cfi8 Macaca mulatta (Rhesus macaque) Neuroligin-4, X-linked ,
macmu-Y4neur Macaca mulatta (Rhesus macaque), M. tonkeana, M. hecki, M. nemestrina, M. maura, M. ochreata, M. nigra, M. nigrescens, Neuroligin 4 Y-linked .
NLS3-Tex30 :
macmu-KANSL3 Macaca mulatta (Rhesus macaque) Uncharacterized protein KIAA1310 ,
macmu-TEX30 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
Pancreatic_lipase :
macmu-f7dn71 Macaca mulatta (Rhesus macaque). Pancreatic lipase ,
macmu-f7hkw9 Macaca mulatta (Rhesus macaque). Pancreatic lipase ,
macmu-f7hm08 Macaca mulatta (Rhesus macaque). Pancreatic lipase .
Pectinacetylesterase-Notum :
macmu-f6zkq5 Macaca mulatta (Rhesus macaque) Uncharacterized protein .
Phospholipase :
macmu-g7mke4 Macaca mulatta (Rhesus macaque). phospholipase A1 ,
macmu-f7hp78 Macaca mulatta (Rhesus macaque). Lipase domain-containing protein ,
macmu-a0a1d5qvu5 Macaca mulatta (Rhesus macaque). Lipase I .
Thyroglobulin :
macmu-g7n054 Macaca mulatta (Rhesus macaque) Thyroglobulin .
Valacyclovir-hydrolase :
macmu-f6the6 Macaca mulatta (Rhesus macaque) Valacyclovir hydrolase Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: macmu-f7ai42 Colored MSA for Carb_B_Chordata (raw)
MWLRALVLATLAAFTAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAVF
LGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCSQDAVAGQVLSEL
FTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS
TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQLAALHW
VQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA
LTAVLVKKGDVKPLAEQIAIAAGCQTTTSAVMVHCLRQKTEEELLETTLK
MKFFSLDLHGDPRESHPFLGTLIDGLLLPKTPEELQAERKFNTVPYMVGF
NKQEFGWIIPMSMGYPLSEGKLDQKTAMSLLWKSYPLVYIAKELIPEAIE
KYLGGTDDPVKKKDLFLDLIADVMFCVPSVIVARHHRDAGAPTYMYEFQY
RPSFSSDMKPKMVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWA
NFARNGNPNGEGLPHWPEYNQEEGYLQIGANTQAAQKLKDKEVAFWTKLF
AKMAVEKPPQTEHIEL
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M W L R A L V L A T L A A F T A W G H P S S P P V V D T V H G K V L G K F V S L E G F A Q P V A V F L G I P F A K P P L G P L R F T P P Q P A E P W S F V K N A T S Y P P M C S Q D A V A G Q V L S E L F T N R K E N I P L K L S E D C L Y L N I Y T P A D L T K K N R L P V M V W I H G G G L M V G A A S T Y D G L A L A A H E N V V V V T I Q Y R L G I W G F F S T G D E H S R G N W G H L D Q L A A L H W V Q D N I A S F G G N P G S V T I F G E S A G G E S V S V L V L S P L A K N L F H R A I S E S G V A L T A V L V K K G D V K P L A E Q I A I A A G C Q T T T S A V M V H C L R Q K T E E E L L E T T L K M K F F S L D L H G D P R E S H P F L G T L I D G L L L P K T P E E L Q A E R K F N T V P Y M V G F N K Q E F G W I I P M S M G Y P L S E G K L D Q K T A M S L L W K S Y P L V Y I A K E L I P E A I E K Y L G G T D D P V K K K D L F L D L I A D V M F C V P S V I V A R H H R D A G A P T Y M Y E F Q Y R P S F S S D M K P K M V I G D H G D E L F S V F G A P F L K E G A S E E E I R L S K M V M K F W A N F A R N G N P N G E G L P H W P E Y N Q E E G Y L Q I G A N T Q A A Q K L K D K E V A F W T K L F A K M A V E K P P Q T E H I E L
Reference
Title: Evolutionary and biomedical insights from the rhesus macaque genomeGibbs RA , Rogers J , Katze MG , Bumgarner R , Weinstock GM , Mardis ER , Remington KA , Strausberg RL , Venter JC and Zwieg AS <166 more author(s)> Gibbs RA , Rogers J , Katze MG , Bumgarner R , Weinstock GM , Mardis ER , Remington KA , Strausberg RL , Venter JC , Wilson RK , Batzer MA , Bustamante CD , Eichler EE , Hahn MW , Hardison RC , Makova KD , Miller W , Milosavljevic A , Palermo RE , Siepel A , Sikela JM , Attaway T , Bell S , Bernard KE , Buhay CJ , Chandrabose MN , Dao M , Davis C , Delehaunty KD , Ding Y , Dinh HH , Dugan-Rocha S , Fulton LA , Gabisi RA , Garner TT , Godfrey J , Hawes AC , Hernandez J , Hines S , Holder M , Hume J , Jhangiani SN , Joshi V , Khan ZM , Kirkness EF , Cree A , Fowler RG , Lee S , Lewis LR , Li Z , Liu YS , Moore SM , Muzny D , Nazareth LV , Ngo DN , Okwuonu GO , Pai G , Parker D , Paul HA , Pfannkoch C , Pohl CS , Rogers YH , Ruiz SJ , Sabo A , Santibanez J , Schneider BW , Smith SM , Sodergren E , Svatek AF , Utterback TR , Vattathil S , Warren W , White CS , Chinwalla AT , Feng Y , Halpern AL , Hillier LW , Huang X , Minx P , Nelson JO , Pepin KH , Qin X , Sutton GG , Venter E , Walenz BP , Wallis JW , Worley KC , Yang SP , Jones SM , Marra MA , Rocchi M , Schein JE , Baertsch R , Clarke L , Csuros M , Glasscock J , Harris RA , Havlak P , Jackson AR , Jiang H , Liu Y , Messina DN , Shen Y , Song HX , Wylie T , Zhang L , Birney E , Han K , Konkel MK , Lee J , Smit AF , Ullmer B , Wang H , Xing J , Burhans R , Cheng Z , Karro JE , Ma J , Raney B , She X , Cox MJ , Demuth JP , Dumas LJ , Han SG , Hopkins J , Karimpour-Fard A , Kim YH , Pollack JR , Vinar T , Addo-Quaye C , Degenhardt J , Denby A , Hubisz MJ , Indap A , Kosiol C , Lahn BT , Lawson HA , Marklein A , Nielsen R , Vallender EJ , Clark AG , Ferguson B , Hernandez RD , Hirani K , Kehrer-Sawatzki H , Kolb J , Patil S , Pu LL , Ren Y , Smith DG , Wheeler DA , Schenck I , Ball EV , Chen R , Cooper DN , Giardine B , Hsu F , Kent WJ , Lesk A , Nelson DL , O'Brien W E , Prufer K , Stenson PD , Wallace JC , Ke H , Liu XM , Wang P , Xiang AP , Yang F , Barber GP , Haussler D , Karolchik D , Kern AD , Kuhn RM , Smith KE , Zwieg AS (- 166) Ref: Science, 316 :222, 2007 : PubMed Abstract ESTHER: Gibbs_2007_Science_316_222 PubMedSearch: Gibbs 2007 Science 316 222 PubMedID: 17431167 Gene_locus related to this paper: macmu-3neur ,
macmu-ACHE ,
macmu-BCHE ,
macmu-f6rul6 ,
macmu-f6sz31 ,
macmu-f6the6 ,
macmu-f6unj2 ,
macmu-f6wtx1 ,
macmu-f6zkq5 ,
macmu-f7aa58 ,
macmu-f7ai42 ,
macmu-f7aim4 ,
macmu-f7buk8 ,
macmu-f7cfi8 ,
macmu-f7cnr2 ,
macmu-f7cu68 ,
macmu-f7flv1 ,
macmu-f7ggk1 ,
macmu-f7hir7 ,
macmu-g7n054 ,
macmu-KANSL3 ,
macmu-TEX30 ,
macmu-Y4neur ,
macmu-g7n4x3 ,
macmu-i2cy02 ,
macmu-f7ba84 ,
macmu-CES2 ,
macmu-h9er02 ,
macmu-a0a1d5rbr3 ,
macmu-a0a1d5q4k5 ,
macmu-g7mxj6 ,
macmu-f7dn71 ,
macmu-f7hkw9 ,
macmu-f7hm08 ,
macmu-g7mke4 ,
macmu-a0a1d5rh04 ,
macmu-h9fud6 ,
macmu-f6qwx1 ,
macmu-f7h4t2 ,
macmu-h9zaw9 ,
macmu-f7h550 ,
macmu-a0a1d5q9w1 ,
macmu-f7gkb9 ,
macmu-f7hp78 ,
macmu-a0a1d5qvu5 Abstract
The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.
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