Gene_Locus Report

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Gene_locus Report for: macmu-g7n054

Macaca mulatta (Rhesus macaque) Thyroglobulin

Relationship
Family|Thyroglobulin
Block| C
Position in NCBI Life Tree|Macaca mulatta
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Primates: N E > Haplorrhini: N E > Simiiformes: N E > Catarrhini: N E > Cercopithecoidea: N E > Cercopithecidae: N E > Cercopithecinae: N E > Macaca: N E > Macaca mulatta: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : CM001260
1 UniProt : G7N054
3 UniProt : G7N054, A0A1D5QES0, A0A1D5R8A5
3 Interpro : G7N054, A0A1D5QES0, A0A1D5R8A5
3 Prodom : G7N054, A0A1D5QES0, A0A1D5R8A5
3 Pfam : G7N054, A0A1D5QES0, A0A1D5R8A5
3 PIRSF : G7N054, A0A1D5QES0, A0A1D5R8A5
3 SUPERFAM : G7N054, A0A1D5QES0, A0A1D5R8A5
Sequence
Graphical view for this peptide sequence: macmu-g7n054
Colored MSA for Thyroglobulin (raw)
HGRLLGRSQAIQLGTSWKQVDQFLGVPYAAPPLAERRFRAPEPLNWTGSW
DASKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNT
MDREGSEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSREVSGNWG
LLDQVAALTWVQTHIRGFGGDPRRVSLAADRAGADVASIHLLMARATNSQ
LFRRAVLMGGSALSPAAIISHERAQQQAVALAKEVSCPVSSSQEVVSCLR
QKPANILNDAQTKLLAVSGPFHYWGPVIDGQFLREPPARALKRSLRAEVD
LLIGSSQDDGLINRAKAVKQFEESQGRTSSKTAFYQALQNSLGGEDSDAR
VEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRAR
GNVFMYHAPESYGRGSLELLADVQFAFGLPFYPAYEGQFSLEEKSLSLKI
MQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPYAGGENYKEFSALLP
NRQGLKKADCSFWSKYISSLKASADGAKGGQSAESEEEELTAGSGLREDL
LSLQEPGSKSYSK
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

HGRLLGRSQAIQLGTSWKQVDQFLGVPYAAPPLAERRFRAPEPLNWTGSW
DASKPRASCWQPGTRTSTSPGVSEDCLYLNVFIPQNVAPNASVLVFFHNT
MDREGSEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSREVSGNWG
LLDQVAALTWVQTHIRGFGGDPRRVSLAADRAGADVASIHLLMARATNSQ
LFRRAVLMGGSALSPAAIISHERAQQQAVALAKEVSCPVSSSQEVVSCLR
QKPANILNDAQTKLLAVSGPFHYWGPVIDGQFLREPPARALKRSLRAEVD
LLIGSSQDDGLINRAKAVKQFEESQGRTSSKTAFYQALQNSLGGEDSDAR
VEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRAR
GNVFMYHAPESYGRGSLELLADVQFAFGLPFYPAYEGQFSLEEKSLSLKI
MQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPYAGGENYKEFSALLP
NRQGLKKADCSFWSKYISSLKASADGAKGGQSAESEEEELTAGSGLREDL
LSLQEPGSKSYSK


References
    Title: Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques
    Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y and Wang X <32 more author(s)>
    Ref: Nat Biotechnol, 29:1019, 2011 : PubMed

            

    Title: Evolutionary and biomedical insights from the rhesus macaque genome
    Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER, Remington KA, Strausberg RL, Venter JC and Zwieg AS <166 more author(s)>
    Ref: Science, 316:222, 2007 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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