Gene_locus Report for: mouse-Kansl3

old K1310_MOUSE mouse-k1310 only central part Pfam A Abhydrolase_5 289 436

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Myomorpha: N E > Muroidea: N E > Muridae: N E > Murinae: N E > Mus [genus]: N E > Mus [subgenus]: N E > Mus musculus: N E

A85-EsteraseD-FGH : mouse-ES10Mus musculus esterase 10.
ABHD6-Lip : mouse-ABHD6Mus musculus (Mouse) Monoacylglycerol lipase ABHD6.
ABHD8 : mouse-Abhd8Mus musculus Q9JMF5-Abhd8 (Mouse) epoxide hydrolase (EC 3.3.2.3).
ABHD10 : mouse-abhda Mus musculus (Mouse) Abhydrolase domain-containing protein 10, mitochondrial.
ABHD11-Acetyl_transferase : mouse-Abhd11Mus musculus (Mouse) Abhydrolase domain-containing protein 11 Williams-Beuren syndrome chromosomal region 21 protein.
ABHD12-PHARC : mouse-abd12Mus musculus (Mouse) abhydrolase domain-containing protein 12 protein c20orf22 CT022 (fragment), mouse-g3uzn6Mus musculus (Mouse) Protein Abhd12b.
ABHD13-BEM46 : mouse-Q80UX8Mus musculus (Mouse) 1110065l07rik protein flj14906 fis Alpha/beta hydrolase domain-containing protein 13.
ABHD16 : mouse-Abhd16aMus musculus (Mouse) Phosphatidylserine lipase ABHD16A, bat5 (hla-b-associated transcript 5) (ng26 protein), mouse-Abhd16bMus musculus (Mouse) similar to chromosome 20 open reading frame 135.
ABHD17-depalmitoylase : mouse-q7m759Mus musculus (Mouse) cgi67 serine protease precursor, mouse-Q8VCV1Mus musculus (Mouse) hypothetical protein, mouse-Q99JW1Mus musculus (Mouse) similar to cgi-67 protein AB17A.
ABHD18 : mouse-Q8C1A9Mus musculus (Mouse)3110057O12RIK Hypothetical alpha/beta-Hydrolases/putative DNA-binding domain.
abh_upf0017 : mouse-ABH15Mus musculus (Mouse) alpha/beta-hydrolases domain-containing protein 15, mouse-abhd1Mus musculus (Mouse) lung alpha/beta hydrolase 1 (Labh1-pending), mouse-abhd3Mus musculus (Mouse) lung alpha/beta hydrolase fold protein 3, mouse-ABHD2Mus musculus (Mouse) alpha/beta hydrolase-2 fold protein 2210009N18RIK.
ACHE : mouse-ACHE Mus musculus (Mouse) acetylcholinesterase.
Acidic_Lipase : mouse-1lipgMus musculus (Mouse) (EC 3.1.1.3) (Gastric lipase) (GL) 2310051b21rik protein, mouse-1llipMus musculus (C57 Black/6X CBA) LAL mRNA for lysosomal acid lipase, mouse-LIPKMus musculus (Mouse) LIPK Lipl2 weakly similar to triacylglycerol lipase, mouse-LIPMMus musculus (Mouse) LIPM Lipm Lipl3 riken cdna 4632427c23 gene, mouse-LIPNMus musculus (Mouse) lipase-like, ab-hydrolase domain containing 3 (fragment), mouse-Lipo1Mus musculus (Mouse) lipase, gastric (EC 3.1.1.3) (gastric lipase) (gl), mouse-Lipo2Mus musculus (Mouse) Lipo2 Lipase, mouse-Lipo4Mus musculus (Mouse) Lipo4 Lipase.
ACPH_Peptidase_S9 : mouse-apehMus musculus (Mouse) hydrolase) (aph) (acylaminoacyl-peptidase).
Acyl-CoA_Thioesterase : mouse-acnt1Mus musculus (Mouse) Acyl-coenzyme A amino acid N-acyltransferase 1, mouse-acot1Mus musculus (Mouse) hydrolase) ACOT1 (cte-I) cytosolic long chain Acyl-CoA thioesterase, mouse-acot2Mus musculus (Mouse) (EC 3.1.2.2) very-long-chain Acyl-CoA thioesterase (MTE-I) ACOT2, mouse-acot3Mus musculus (Mouse) (peroxisomal long-chain Acyl-CoA thioesterase 2) (pte-IA) (EC 3.1.2.2), mouse-acot4Mus musculus (Mouse) peroxisomal long chain Acyl-CoA thioesterase Ib (pte-Ib) (pte-2b), mouse-acot5Mus musculus (Mouse) (peroxisomal cytosolic Acyl-CoA thioesterase Ic), mouse-BAATMus musculus (Mouse) bile acid CoA: amino acid n-acyltransferase (EC 3.1.2.2), mouse-ACOT6Mus musculus (Mouse)acyl-CoA thioesterase 6 (EC 3.1.2.2). Weakly similar to peroxisomal acyl-coenzyme A thioester hydrolase2, mouse-Q8BGG9Mus musculus (Mouse) Similar to bile acid coenzyme A: amino acid N-acyltransferase.
Arb2_FAM172A : mouse-f172aMus musculus (Mouse). Cotranscriptional regulator FAM172A.
Arylacetamide_deacetylase : mouse-adcl3Mus musculus (Mouse) Arylacetamide deacetylase-like 3, mouse-adcl4Mus musculus (Mouse) Arylacetamide deacetylase-like 4 Hypothetical esterase/lipase/thioesterase family active site containing protein, mouse-arylaMus musculus (Mouse) arylacetamide deacetylase and 5033417e09rik protein, mouse-Q8BLF1Mus musculus (Mouse) KIAA1363 NCEH1 neutral cholesterol ester hydrolase 1 B230106I24RIK, mouse-b1avu7Mus musculus (Mouse). Uncharacterized protein, mouse-b2rwd2Mus musculus (Mouse). Arylacetamide deacetylase-like 2, mouse-j3qpi0Mus musculus (Mouse). Uncharacterized protein, mouse-w4vsp6Mus musculus (Mouse). MCG67716.
BCHE : mouse-BCHEMus musculus mRNA for butyrylcholinesterase.
Carboxypeptidase_S10 : mouse-CPMacMus musculus RIKEN 4933436L16RIK CPMac, mouse-Ppgb Mus musculus (Mouse) Lysosomal protective protein, Cathepsin A Ctsa, Protective protein for beta-galactosidase (Mo54) Ppgb, mouse-RISCMus musculus RISC retinoid-inducible serine carboxypeptidase HSCP1 (serine carboxypeptidase 1).
Carb_B_Chordata : mouse-cauxinMus musculus (Mouse) est5a (Ces5a) est7 (Ces7) carboxylesterase-like urinary excreted protein, mouse-Ces1aMus musculus Ces1a LOC2445 Q5FWH4, mouse-Ces1bMus musculus (Mouse) Putative uncharacterized protein Gm5158, mouse-Ces1cMus musculus mRNA for carboxylesterase, Ces1c lung surfactant convertase, Liver carboxylesterase N, PES-N clone MGC:18575, mouse-Ces1dMus musculus (Mouse) triacylglycerol hydrolase (tgh) Fatty acid ethyl ester synthase Carboxylesterase 3 (EC 3.1.1.1), mouse-Ces1eMus musculus esterase-22 (egasyn) Es-22 E.R.-targeting prot. of beta-glucuronidase, mouse-Ces1fMus musculus (Mouse) carboxylesterase ML1, CESmML1 61.6 kda protein ES-4 (EC 3.1.1.1), mouse-Ces1gMus musculus Ces1g EST1 RIKEN 2cxes mRNA for carboxylesterase, mouse-Ces1hMus musculus Ces1h RIKEN cDNA 2310039D24 gene (2310039D24Rik),XP_134476, mouse-Ces2aMus musculus (Mouse) Protein Ces2a Ces6 carboxylesterase 6 (Intestine, liver) AI266984, mouse-Ces2bMus musculus (Mouse) Ces2b hypothetical protein bc015286, mouse-Ces2c Mus musculus (Mouse) Ces2c similar to carboxylesterase 2 (intestine, liver) Acylcarnitine hydrolase, mouse-Ces2d-psMus musculus (Mouse) Ces2d-ps carboxylesterase 2D, pseudogene, mouse-Ces2eMus musculus Ces2e Ces5 carboxylesterase, Pyrethroid hydrolase, mouse-Ces2fMus musculus (Mouse) Ces2f Uncharacterized protein, mouse-Ces2gMus musculus (Mouse) hypothetical 62.7 kda protein, mouse-Ces2hMus musculus Ces2h carboxylesterase 2 isoform 1, mouse-Ces3aMus musculus Ces3a liver carboxylesterase esterase 31 Es31, mouse-Ces3bMus musculus (Mouse) Liver carboxylesterase 31-like, Es31L, mouse-Ces4aMus musculus (Mouse) Carboxylesterase 4A (Ces4a) Carboxylesterase 8 (Ces8) pI 6.1 esterase (ES-10) ES-HVEL.
CGI-58_ABHD5_ABHD4 : mouse-abhd4Mus musculus (Mouse) abhydrolase domain-containing protein 4 similar to hypothetical protein flj12816, mouse-abhd5Mus musculus (Mouse) cgi-58 RIKEN AK004873 gene.
Cholesterol_esterase : mouse-pchesMus musculus pancreatic/mammary gland cholesterol esterase.
CIB-CCG1-interacting-factor-B : mouse-c1ibMus musculus (Mouse) ccg1-interacting factor b, mouse-Dorz1Mus musculus (Mouse)1110013B16RIK Dorz1 similar to dkfzp564o243 protein.
CMBL : mouse-CMBLMus musculus (Mouse) Carboxymethylenebutenolidase homolog.
DPP4N_Peptidase_S9 : mouse-dpp4M.musculus mRNA for dipeptidyl peptidase IV, mouse-DPP6Mus musculus (Mouse) dipeptidyl aminopeptidase-like protein 6 (fragment), mouse-dpp8Mus musculus RIKEN dpp8, mouse-dpp9Mus musculus (Mouse) dipeptidyl peptidase 9 homolog mflj00334 protein, mouse-dpp10Mus musculus DPP-10 Dipeptidyl peptidase IV-related protein RIKEN cDNA 6430601K09 gene (6430601K09Rik), mRNA, mouse-FAPMus musculus (Mouse) fibroblast activation protein.
Duf_676 : mouse-F135AMus musculus (Mouse) hypothetical Esterase/lipase/thioesterase family active site containing protein, mouse-Q9DAI6Mus musculus (Mouse) family active site containing protein, similarity 135, member B.
Duf_726 : mouse-tmco4Mus musculus (Mouse) Transmembrane and coiled-coil domain-containing protein 4.
Duf_829 : mouse-tmm53Mus musculus (Mouse) Transmembrane protein 53.
Epoxide_hydrolase : mouse-EPHX1Mus musculus (Mouse) epoxide hydrolase mEH (EC 3.3.2.3), mouse-ephx3Mus musculus (Mouse) Abhd9 ephx3 Epoxide_hydrolase sequence, mouse-ephx4Mus musculus (Mouse) epoxide hydrolase-related protein, mouse-hyes Mus musculus soluble epoxide hydrolase 2, cytoplasmic (Ephx2), mRNA.
FSH1 : mouse-OVCA2Mus musculus (Mouse) 2310011m22rik protein (ovca2).
Hepatic_Lipase : mouse-1hlipMus musculus (Mouse), Mus spretus (Western Mediterranean mouse) (Algerian mouse) hepatic triacylglycerol lipase.
Hormone-sensitive_lipase_like : mouse-hslipMus musculus mRNA for hormone sensitive lipase.
Hydrolase_RBBP9_YdeN : mouse-rbbp9Mus musculus (Mouse), Mus spretus (Western Mediterranean mouse), (Retinoblastoma-binding protein 9 protein) B5T overexpressed gene protein (bog protein).
Kynurenine-formamidase : mouse-KFAMus musculus Kynurenine formamidase (EC 3.5.1.9) Afmid Ammd cDNA 9030621K19 gene (9030621K19Rik).
LIDHydrolase : mouse-LdahMus musculus (Mouse) lipid droplet-associated hydrolase (LDAH) C2orf43 CB043 UPF0554.
Lipase_3 : mouse-DGLBMus musculus (Mouse) Daglb Sn1-specific diacylglycerol lipase beta 64.9 kda protein, mouse-q6wqj1Mus musculus (Mouse) Dagla neural stem cell-derived dendrite regulator DAGLA.
Lipoprotein_Lipase : mouse-LipgMus musculus (Mouse) Lipg endothelial lipase, mouse-lipliMus musculus lipoprotein lipase.
LYsophospholipase_carboxylesterase : mouse-lypl1Mus musculus (Mouse) lysophospholipase-like protein 1 (EC 3.1.2.-) 26.3 kda protein, mouse-lypla1Mus musculus lysophospholipase 1 (Lypla1)(lysopla I), mRNA, mouse-lypla2Mus musculus lysophospholipase 2 (Lypla2), mRNA.
Maspardin-ACP33-SPG21_like : mouse-SPG21Mus musculus (Mouse) hypothetical Maspardin-ACP33-SPG21 Spg21 Spastic paraplegia 21 homolog (Human).
MEST-like : mouse-MESTMus musculus Mouse and Mus musculus molossinus (Japanese house mouse) Mesoderm-specific transcript protein.
Monoglyceridelipase_lysophospholip : mouse-MGLLMus musculus (Mouse) monoglyceride lipase (EC 3.1.1.23).
Ndr_family : mouse-ndr1Mus musculus (Mouse) ndr1, mouse-ndr2 Mus musculus (Mouse) ndrg2 protein (ndr2 protein), mouse-ndr3Mus musculus (Mouse) ndrg3 protein (ndr3 protein), mouse-ndr4Mus musculus (Mouse) NDRG4 ndrg4 protein mkiaa1180.
Neuroligin : mouse-1neur Mus musculus (Mouse) neuroligin 1, KIAA1070 clone MGC:7622 complete cds, mouse-2neur Mus musculus (Mouse) neuroligin 2 (Nlgn2), mRNA, mouse-3neur Mus musculus (Mouse) partial mRNA for neuroligin 3 protein, mouse-4neurMus musculus (Mouse) neuroligin 4.
NLS3-Tex30 : mouse-Tex30Mus musculus (Mouse) Tex30 Testis-expressed sequence 30 protein, C13orf27 homolog.
PAF-Acetylhydrolase : mouse-paf2Mus musculus (Mouse) similar to platelet-activating factor acetylhydrolase 2 (40 kda), mouse-pafaMus musculus plasma PAF acetylhydrolase.
Palmitoyl-protein_thioesterase : mouse-pptMus musculus (Mouse) palmitoyl-protein thioesterase, mouse-PPT2Mus musculus (Mouse) palmitoyl-protein thioesterase 2.
Pancreatic_lipase : mouse-1plipMus musculus RIKEN Pancreatic lipase, mouse-1plrpMus musculus (Mouse) pancreatic lipase related protein 1, mouse-LIPR2Mus musculus mRNA for cytotoxic T lymphocyte lipase.
PC-sterol_acyltransferase : mouse-C87498Mus musculus (Mouse) similar to LCAT-like lysophospholipase (llpl), mouse-lcatMus musculus mRNA for phosphatidylcholine-sterol acyltransferase ( lecithin: cholesterol acyltransferase).
Pectinacetylesterase-Notum : mouse-notumMus musculus (Mouse) Protein notum homolog.
PGAP1 : mouse-q3uuq7Mus musculus (Mouse) gpi deacylase full insert sequence. (fragment), mouse-srac1Mus musculus (Mouse) Protein SERAC1.
Phospholipase : mouse-LIPHMus musculus (Mouse) similar to lacrimal lipase, mouse-psplipMus musculus Similar to phosphatidylserine-specific phospholipase A1alpha, mouse-f6yqt7Mus musculus (Mouse). Lipase, member I.
PPase_methylesterase_euk : mouse-PPME1Mus musculus (Mouse) similar to protein phosphatase methylesterase-1.
Prolylcarboxypeptidase : mouse-dpp2Mus musculus (Mouse) Dipeptidyl aminopeptidase II Dipeptidyl peptidase 7, mouse-pcpMus musculus (Mouse) prcp protein 2510048k03rik protein prolylcarboxypeptidase, mouse-tsspMus musculus (Mouse) thymus-specific serine protease precursor (EC 3.4.-.-) ottmusp00000000643.
S9N_PPCE_Peptidase_S9 : mouse-ppceMus musculus (Mouse) (PE) prolyl endopeptidase POP PREP.
S9N_PREPL_Peptidase_S9 : mouse-Q8C167Mus musculus (Mouse) PERLP unknown (protein for mgc:7980) mkiaa0436.
SERHL : mouse-SERHLMus musculus (Mouse) serine hydrolase-like protein 0610008b10rik protein and isoforms shl-2 (1110019m09rik protein).
Thioesterase : mouse-AI607300Mus musculus (Mouse) hydrolase (mch) SAST, mouse-FASNMus musculus (Mouse) fatty acid synthase FAS oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) Thioesterase domain.
Thyroglobulin : mouse-thyroMus musculus thyroglobulin cDNA.
Valacyclovir-hydrolase : mouse-bphlMus musculus (Mouse) biphenyl hydrolase-like, breast epithelial mucin-assoc AG BPHL (mcnaa), Valacyclovir hydrolase 2010012d11 rik protein

Title: The transcriptional landscape of the mammalian genome
Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B and Hayashizaki Y <184 more author(s)> Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y (- 184)
Ref: Science, 309:1559, 2005 : PubMed
Abstract


ESTHER: Carninci_2005_Science_309_1559
PubMedSearch: Carninci 2005 Science 309 1559
PubMedID: 16141072
Gene_locus related to this paper: mouse-abhd1, mouse-abhd3, mouse-abhd4, mouse-acot4, mouse-adcl4, mouse-DGLB, mouse-ephx3, mouse-Kansl3, mouse-lipli, mouse-LIPN, mouse-Ppgb, mouse-q3uuq7, mouse-srac1, mouse-Tex30, mouse-tmco4, mouse-tmm53, mouse-f172a

Abstract

This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5' and 3' boundaries of 181,047 transcripts with extensive variation in transcripts arising from alternative promoter usage, splicing, and polyadenylation. There are 16,247 new mouse protein-coding transcripts, including 5154 encoding previously unidentified proteins. Genomic mapping of the transcriptome reveals transcriptional forests, with overlapping transcription on both strands, separated by deserts in which few transcripts are observed. The data provide a comprehensive platform for the comparative analysis of mammalian transcriptional regulation in differentiation and development.



        

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R and Hayashizaki Y <127 more author(s)> Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schonbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y (- 127)
Ref: Nature, 420:563, 2002 : PubMed
Abstract


ESTHER: Okazaki_2002_Nature_420_563
PubMedSearch: Okazaki 2002 Nature 420 563
PubMedID: 12466851
Gene_locus related to this paper: mouse-1lipg, mouse-1llip, mouse-1plrp, mouse-3neur, mouse-ABH15, mouse-abhd4, mouse-abhd5, mouse-Abhd8, mouse-Abhd11, mouse-abhda, mouse-acot4, mouse-adcl4, mouse-AI607300, mouse-BAAT, mouse-bphl, mouse-C87498, mouse-Ldah, mouse-Ces1d, mouse-Ces2e, mouse-CMBL, mouse-DGLB, mouse-dpp9, mouse-ES10, mouse-F135A, mouse-FASN, mouse-hslip, mouse-hyes, mouse-Kansl3, mouse-LIPH, mouse-LIPK, mouse-lipli, mouse-LIPM, mouse-lypla1, mouse-lypla2, mouse-MEST, mouse-MGLL, mouse-ndr4, mouse-OVCA2, mouse-pafa, mouse-pcp, mouse-ppce, mouse-Ppgb, mouse-PPME1, mouse-q3uuq7, mouse-Q8BLF1, mouse-ACOT6, mouse-Q8C1A9, mouse-Q9DAI6, mouse-Q80UX8, mouse-Q8BGG9, mouse-Q8C167, mouse-rbbp9, mouse-SERHL, mouse-tssp

Abstract

Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the mouse, and to ensure that each is represented in a physical collection of clones. Here we report the manual annotation of 60,770 full-length mouse complementary DNA sequences. These are clustered into 33,409 'transcriptional units', contributing 90.1% of a newly established mouse transcriptome database. Of these transcriptional units, 4,258 are new protein-coding and 11,665 are new non-coding messages, indicating that non-coding RNA is a major component of the transcriptome. 41% of all transcriptional units showed evidence of alternative splicing. In protein-coding transcripts, 79% of splice variations altered the protein product. Whole-transcriptome analyses resulted in the identification of 2,431 sense-antisense pairs. The present work, completely supported by physical clones, provides the most comprehensive survey of a mammalian transcriptome so far, and is a valuable resource for functional genomics.