Mus musculus (Mouse) hydrolase) ACOT1 (cte-I) cytosolic long chain Acyl-CoA thioesterase
The mouse ACOT gene cluster comprises six genes with localizations in cytosol (ACOT1), mitochondria (ACOT2), and peroxisomes (ACOT3-6). The corresponding human gene cluster contains only three genes (ACOT1, ACOT2, and ACOT4) coding for full-length thioesterase proteins only ACOT4 is peroxisomal
MEATLNLEPS GRSCWDEPLS IAVRGLAPEQ PVTLRSVLRD EKGALFRAHA RYRADSHGEL DLARTPALGG SFSGLEPMGL LWAMEPDRPF WRLVKRDVQT PFVVELEVLD GHEPDGGQRL AHAVHERHFL APGVRRVPVR EGRVRATLFL PPEPGPFPGI IDLFGVGGGL LEYRASLLAG KGFAVMALAY YNYDDLPKNM ETMHMEYFEE AVNYLRSHPE VKGPGIGLLG ISKGGELGLA MASFLKGITA AVVINGSVAA VGNTISYKDE TIPPVTILRN QVKMTKDGLK DVVDALQSPL VDKKSFIPVE RSDTTFLFLV GQDDHNWKSE FYADEISKRL QAHGKEKPQI ICYPAAGHYI EPPYFPLCSA GMHLLVGANI TFGGEPKPHA MAQLDAWQQL QTFFHKQLGS ECLHVSPKI
Title : Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs - Hunt_2006_FASEB.J_20_1855 |
Author(s) : Hunt MC , Rautanen A , Westin MA , Svensson LT , Alexson SE |
Ref : FASEB Journal , 20 :1855 , 2006 |
Abstract : Hunt_2006_FASEB.J_20_1855 |
ESTHER : Hunt_2006_FASEB.J_20_1855 |
PubMedSearch : Hunt_2006_FASEB.J_20_1855 |
PubMedID: 16940157 |
Gene_locus related to this paper: human-ACOT1 , human-ACOT2 , human-ACOT4 , human-ACOT6 , mouse-acot1 , mouse-acot2 , mouse-acot3 , mouse-acot4 , mouse-acot5 , mouse-ACOT6 |
Title : The peroxisome proliferator-induced cytosolic type I acyl-CoA thioesterase (CTE-I) is a serine-histidine-aspartic acid alpha\/beta hydrolase - Huhtinen_2001_J.Biol.Chem_277_3424 |
Author(s) : Huhtinen K , O'Byrne J , Lindquist PJ , Contreras JA , Alexson SE |
Ref : Journal of Biological Chemistry , 277 :3424 , 2001 |
Abstract : Huhtinen_2001_J.Biol.Chem_277_3424 |
ESTHER : Huhtinen_2001_J.Biol.Chem_277_3424 |
PubMedSearch : Huhtinen_2001_J.Biol.Chem_277_3424 |
PubMedID: 11694534 |
Gene_locus related to this paper: mouse-acot1 |
Title : Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism - Hunt_2000_Cell.Biochem.Biophys_32 Spring_317 |
Author(s) : Hunt MC , Lindquist PJ , Nousiainen S , Huttunen M , Orii K , Svensson TL , Aoyama T , Hashimoto T , Diczfalusy U , Alexson SE |
Ref : Cell Biochem Biophys , 32 Spring :317 , 2000 |
Abstract : Hunt_2000_Cell.Biochem.Biophys_32 Spring_317 |
ESTHER : Hunt_2000_Cell.Biochem.Biophys_32 Spring_317 |
PubMedSearch : Hunt_2000_Cell.Biochem.Biophys_32 Spring_317 |
PubMedID: 11330065 |
Gene_locus related to this paper: mouse-acot1 , mouse-acot2 |
Title : Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism - Hunt_1999_J.Biol.Chem_274_34317 |
Author(s) : Hunt MC , Nousiainen SE , Huttunen MK , Orii KE , Svensson LT , Alexson SE |
Ref : Journal of Biological Chemistry , 274 :34317 , 1999 |
Abstract : Hunt_1999_J.Biol.Chem_274_34317 |
ESTHER : Hunt_1999_J.Biol.Chem_274_34317 |
PubMedSearch : Hunt_1999_J.Biol.Chem_274_34317 |
PubMedID: 10567408 |
Gene_locus related to this paper: mouse-acot1 , mouse-acot2 , mouse-acot3 , mouse-acot4 |
Title : Molecular cloning of the peroxisome proliferator-induced 46-kDa cytosolic acyl-CoA thioesterase from mouse and rat liver--recombinant expression in Escherichia coli, tissue expression, and nutritional regulation. - |
Author(s) : Lindquist PJG , Svensson TL , Alexson SEH |
Ref : European Journal of Biochemistry , 251 :631 , 1998 |
PubMedID: 9490035 |
Gene_locus related to this paper: mouse-acot1 , ratno-acot1 |