Gene_Locus Report

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Gene_locus Report for: mouse-ephx3

Mus musculus (Mouse) Abhd9 ephx3 Epoxide_hydrolase sequence

Relationship
Family|Epoxide_hydrolase
Block| X
Position in NCBI Life Tree|Mus musculus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Myomorpha: N E > Muroidea: N E > Muridae: N E > Murinae: N E > Mus [genus]: N E > Mus [subgenus]: N E > Mus musculus: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AK132483, BC145797
2 UniProt : Q3V1F8, A6H695
2 UniProt : Q3V1F8, A6H695
2 Interpro : Q3V1F8, A6H695
2 Prodom : Q3V1F8, A6H695
2 Pfam : Q3V1F8, A6H695
2 PIRSF : Q3V1F8, A6H695
2 SUPERFAM : Q3V1F8, A6H695
Sequence
Graphical view for this peptide sequence: mouse-ephx3
Colored MSA for Epoxide_hydrolase (raw)
MRGGSICPSRASVSSTGPVDSDSTVESQNKGGGLLAPAPLAQSPDHGGSV
VVPERKDMPEFVVTALLAPSRLSLKLLRALVMSLVYLAALVAAFVYSCIA
LTHVMCRPRRGCCGRQRLSPPECLRDPTLGEHCFLTLRVSVPPVKSSGLR
LHYVSAGHGNGPLMLFLHGFPENWFSWRYQLREFQSHFHVVAVDMRGYSP
SDAPKEVDCYTIDLLLDDIKDTILGLGYSKCILVSHDWGASLAWEFSIYY
PSLVERMVVANGPPMSVIQEYSIHHIGQIFRSNYMFLFQLPWLPEKLLSM
SDFQILKDTFTHRKNGIPGLTPSELEAFLYHFSQPGCLTGPINYYRNVFR
NFPLEPKKLSTPTLLLWGEKDFAFQQGLVEAIGRHFVPGRLESHILPGSG
HWIPQSHPQEMHQYMWAFLQDLLG
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MRGGSICPSRASVSSTGPVDSDSTVESQNKGGGLLAPAPLAQSPDHGGSV
VVPERKDMPEFVVTALLAPSRLSLKLLRALVMSLVYLAALVAAFVYSCIA
LTHVMCRPRRGCCGRQRLSPPECLRDPTLGEHCFLTLRVSVPPVKSSGLR
LHYVSAGHGNGPLMLFLHGFPENWFSWRYQLREFQSHFHVVAVDMRGYSP
SDAPKEVDCYTIDLLLDDIKDTILGLGYSKCILVSHDWGASLAWEFSIYY
PSLVERMVVANGPPMSVIQEYSIHHIGQIFRSNYMFLFQLPWLPEKLLSM
SDFQILKDTFTHRKNGIPGLTPSELEAFLYHFSQPGCLTGPINYYRNVFR
NFPLEPKKLSTPTLLLWGEKDFAFQQGLVEAIGRHFVPGRLESHILPGSG
HWIPQSHPQEMHQYMWAFLQDLLG


References
    Title: Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function
    Edin ML, Yamanashi H, Boeglin WE, Graves JP, DeGraff LM, Lih FB, Zeldin DC, Brash AR
    Ref: Journal of Biological Chemistry, 296:100198, 2021 : PubMed

            

    Title: The transcriptional landscape of the mammalian genome
    Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B and Hayashizaki Y <184 more author(s)>
    Ref: Science, 309:1559, 2005 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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