Gene_locus Report for: mycpa-Q8KY59 Mycobacterium paratuberculosis antigen 85a complex
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Corynebacteriales: N E > Mycobacteriaceae: N E > Mycobacterium: N E > Mycobacterium avium complex (MAC): N E > Mycobacterium avium: N E > Mycobacterium avium subsp. paratuberculosis: N E 6_AlphaBeta_hydrolase :
mycpa-q73ry6 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73s17 Mycobacterium paratuberculosis Mycobacterium avium (strain 104), alpha/beta fold family protein ,
mycpa-q73sm2 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) bpoc_2 ,
mycpa-q73tc9 Mycobacterium paratuberculosis, Mycobacterium avium Putative uncharacterized protein ,
mycpa-q73ur3 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) lipv ,
mycpa-q73uy7 Mycobacterium paratuberculosis and Mycobacterium avium (strain 104) hpx ,
mycpa-q73v88 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73vm9 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73wj1 Mycobacterium paratuberculosis bpob ,
mycpa-q73ws9 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73x18 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73ya7 Mycobacterium paratuberculosis (and strain 104) hypothetical protein ,
mycpa-q73z93 Mycobacterium paratuberculosis Mycobacterium avium (strain 104), alpha/beta fold family protein, putative ,
mycpa-q742v3 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q743k3 Mycobacterium paratuberculosis bpoa ,
mycpa-q743x3 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) alpha/beta hydrolase fold family protein ,
mycpa-q744u6 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q744y3 Mycobacterium paratuberculosis Mycobacterium avium (strain 104)hypothetical protein .
A85-Est-Putative :
mycpa-q73rz3 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q740k0 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q742t6 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein .
A85-Feruloyl-Esterase :
mycpa-q73sr2 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q743h7 Mycobacterium paratuberculosis hypothetical protein .
A85-Mycolyl-transferase :
mycav-a85a Mycobacterium avium and Mycobacterium paratuberculosis ag85A fibronectin-binding protein A antigen 85-a (mycolyl transferase) (EC 2.3.1.122) (fragment) ,
mycav-a85b Mycobacterium avium (strain 104) complex B ag85B and Mycobacterium paratuberculosis fbpb fibronectin-binding protein B ,
mycpa-Q8L371 Mycobacterium paratuberculosis 85b protein ,
mycpa-q745l2 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) fbpc1 .
Abhydrolase_9 :
mycpa-q741s1 Mycobacterium paratuberculosis; Mycobacterium avium; Mycobacterium avium subsp.; Mycobacterium sp. Putative uncharacterized protein .
AlphaBeta_hydrolase :
mycpa-q73w68 Mycobacterium paratuberculosis hypothetical protein .
BD-FAE :
mycpa-lipM Mycobacterium paratuberculosis and Mycobacterium avium (strain 104) lipm ,
mycpa-lipO Mycobacterium paratuberculosis and Mycobacterium avium (strain 104) lipo ,
mycpa-lipQ Mycobacterium paratuberculosis and Mycobacterium avium (strain 104) lipq ,
mycpa-q73tr2 Mycobacterium paratuberculosis and Mycobacterium avium (strain 104) lipc ,
mycpa-q73tr3 Mycobacterium paratuberculosis lipw .
Carbon-carbon_bond_hydrolase :
mycpa-q73ub4 Mycobacterium paratuberculosis, Mycobacterium avium, hypothetical protein ,
mycpa-q73zz9 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase ,
mycpa-q742y5 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q742z2 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) 2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase ,
mycpa-q743u3 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase .
Carb_B_Bacteria :
mycpa-lipT Mycobacterium paratuberculosis; Mycobacterium avium; Mycobacterium bouchedurhonense. lipt lppt ,
mycpa-MAP2689c Mycobacterium paratuberculosis, Mycobacterium avium, Mycobacterium avium subsp. hominissuis, subsp. paratuberculosis, Mycobacterium sp Hypothetical protein .
Cocaine_esterase :
mycpa-q73vv9 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73wu7 Mycobacterium paratuberculosis hypothetical protein .
Cutinase :
mycav-Q9KK87 Mycobacterium avium Mycobacterium paratuberculosis, Mycobacterium intracellulare, serine esterase cutinase ,
mycpa-q73s39 Mycobacterium paratuberculosis, Mycobacterium avium, hypothetical protein ,
mycpa-q73s40 Mycobacterium paratuberculosis, Mycobacterium avium, hypothetical protein ,
mycpa-q73u73 Mycobacterium paratuberculosis; Mycobacterium intracellulare; Mycobacterium avium subsp. paratuberculosis hypothetical protein ,
mycpa-q73ue0 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73xk5 Mycobacterium paratuberculosis, Mycobacterium avium , hypothetical protein ,
mycpa-q73yd6 Mycobacterium paratuberculosis, Mycobacterium avium, hypothetical protein ,
mycpa-q73ze1 Mycobacterium paratuberculosiss, Mycobacterium avium hypothetical protein ,
mycpa-q73zx5 Mycobacterium paratuberculosis, Mycobacterium avium hypothetical protein ,
mycpa-q744k8 Mycobacterium paratuberculosis, Mycobacterium avium, Cutinase ,
mycpa-q745l1 Mycobacterium paratuberculosis, Mycobacterium avium, hypothetical protein .
Dienelactone_hydrolase :
mycpa-q73vz1 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73z00 Mycobacterium paratuberculosis hypothetical protein .
Duf_1023 :
mycpa-q73ru8 Mycobacterium paratuberculosis Mycobacterium avium (strain 104), hypothetical protein .
Duf_1100-S :
mycpa-q73tg1 Mycobacterium paratuberculosis hypothetical protein .
Epoxide_hydrolase :
mycpa-q73u18 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) ephf ,
mycpa-q73ut4 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73vx6 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73w28 Mycobacterium paratuberculosis and Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73wj3 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) Epoxide hydrolase EphC ,
mycpa-q73yg7 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73yk0 Mycobacterium paratuberculosis Short chain dehydrogenase ephd Mycobacterium avium (strain 104) ,
mycpa-q743z5 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) epha (EC 3.3.2.3) (epoxide hydrolase) ,
mycpa-q744d7 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) ephe .
Fungal-Bact_LIP :
mycpa-q73ry9 Mycobacterium paratuberculosis Mycobacterium parascrofulaceum, Mycobacterium avium, hypothetical protein ,
mycpa-q740q6 Mycobacterium paratuberculosis, Mycobacterium avium, Mycobacterium parascrofulaceum hypothetical protein .
Haloalkane_dehalogenase-HLD1 :
mycav-DHMA Mycobacterium avium Mycobacterium paratuberculosis; Mycobacterium sp.; Mycobacterium tuberculosis haloalkane dehalogenase ,
mycpa-q744j6 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein .
Haloperoxidase :
mycpa-q73u31 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) bpoc_1 non-haem bromoperoxidase bpo-a2 (EC 1.11.1.-) .
Homoserine_transacetylase :
mycpa-q73ub0 Mycobacterium paratuberculosis Mycobacterium avium (strain 104)Homoserine O-trans-acetylase meta .
Hormone-sensitive_lipase_like :
mycpa-lipI Mycobacterium paratuberculosis lipi ,
mycpa-q73tx3 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73vk7 Mycobacterium paratuberculosis lipn ,
mycpa-q73xe5 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73xw1 Mycobacterium paratuberculosis lipk ,
mycpa-q73z68 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73zz5 Mycobacterium paratuberculosis, Mycobacterium avium,hypothetical protein ,
mycpa-q740a6 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q740b3 Mycobacterium paratuberculosis liph ,
mycpa-q741r4 Mycobacterium paratuberculosis lipu .
Monoglyceridelipase_lysophospholip :
mycpa-q73tu6 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73vt9 Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) Putative uncharacterized protein .
PE-PPE :
mycpa-q73xs5 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) Putative uncharacterized protein .
PHA_synth_III_C :
mycpa-q740g2 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein .
Proline_iminopeptidase :
mycpa-q743a1 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein .
S9N_PPCE_Peptidase_S9 :
mycpa-q73sx2 Mycobacterium paratuberculosis hypothetical protein .
S9N_PREPL_Peptidase_S9 :
mycpa-q743h0 Mycobacterium paratuberculosis ptrba .
Thioesterase :
mycpa-q73th3 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73th6 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73xy2 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q73yt6 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q740d1 Mycobacterium paratuberculosis hypothetical protein ,
mycpa-q745k9 Mycobacterium paratuberculosis pks13 .
Tiancimycin-TnmK-Tripeptidase-HIP :
mycpa-q73yi8 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein ,
mycpa-q73yi9 Mycobacterium paratuberculosis Mycobacterium avium (strain 104) hypothetical protein .
Xaa-Pro-like_dom :
mycpa-q73z76 Mycobacterium paratuberculosis hypothetical protein Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can
retrieve all strain data
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Mycobacterium avium subsp. paratuberculosis K-10:
N ,
E .
Mycobacterium avium subsp. paratuberculosis:
N ,
E .
Mycobacterium avium subsp. paratuberculosis S397:
N ,
E .
Mycobacterium avium subsp. paratuberculosis MAP4:
N ,
E .
Mycobacterium avium subsp. paratuberculosis S5:
N ,
E .
Mycobacterium avium subsp. paratuberculosis 10-4404:
N ,
E .
Mycobacterium avium subsp. paratuberculosis 10-8425:
N ,
E .
Mycobacterium avium subsp. paratuberculosis 08-8281:
N ,
E .
Mycobacterium avium subsp. paratuberculosis 10-5975:
N ,
E .
Mycobacterium avium subsp. paratuberculosis 10-5864:
N ,
E .
Mycobacterium avium subsp. paratuberculosis 11-1786:
N ,
E .
Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: mycpa-Q8KY59 Colored MSA for A85-Mycolyl-transferase (raw)
MTLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLP
VEYLQVPSAAMGRDIKVQFQSGGANSPALYLLDGMRAQDDFNGWDINTPA
FEWYNQSGISVAMPVGGQSSFYSDWYKPACGKAGCTTYKWETFLTSELPQ
YLSAQKQVKPTGSGVVGLADGRLLRRLSWAATTPDQFVYAGSLSALVELV
ARAWARRLIGLAMGTPVATRPPTCGVRRRTRPGPATTRRCRSASLVANNT
RIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNLKFQDAYNGAGGHNAVWN
FDANGTHDWPYWGAQLQAMKPDLQSVLGATPGAGPATAAATNAGNGQGT
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M T L V D R L R G A V A G M P R R L V V G A A G A A L L S G L I G A V G G S A T A G A F S R P G L P V E Y L Q V P S A A M G R D I K V Q F Q S G G A N S P A L Y L L D G M R A Q D D F N G W D I N T P A F E W Y N Q S G I S V A M P V G G Q S S F Y S D W Y K P A C G K A G C T T Y K W E T F L T S E L P Q Y L S A Q K Q V K P T G S G V V G L A D G R L L R R L S W A A T T P D Q F V Y A G S L S A L V E L V A R A W A R R L I G L A M G T P V A T R P P T C G V R R R T R P G P A T T R R C R S A S L V A N N T R I W V Y C G N G K P S D L G G D N L P A K F L E G F V R T S N L K F Q D A Y N G A G G H N A V W N F D A N G T H D W P Y W G A Q L Q A M K P D L Q S V L G A T P G A G P A T A A A T N A G N G Q G T
Reference
Title: Cloning and characterization of the genes coding for antigen 85A, 85B and 85C of Mycobacterium avium subsp. paratuberculosisDheenadhayalan V , Shin KS , Chang CF , Chang CD , Wang SJ , McDonough S , McDonough P , Stehman S , Shin S and Chang YF <1 more author(s)> Dheenadhayalan V , Shin KS , Chang CF , Chang CD , Wang SJ , McDonough S , McDonough P , Stehman S , Shin S , Torres A , Chang YF (- 1) Ref: DNA Sequence, 13 :287, 2002 : PubMed Abstract ESTHER: Dheenadhayalan_2002_DNA.Seq_13_287 PubMedSearch: Dheenadhayalan 2002 DNA.Seq 13 287 PubMedID: 12592709 Gene_locus related to this paper: mycav-a85c ,
mycpa-Q8KY59 Abstract
Three genes encoding the secreted proteins (antigen 85-A, B, and C) of Mycobacterium avium subsp. paratuberculosis were cloned, sequenced and studied. The complete sequences of these three 85-complex proteins revealed their similarity with 85-complex proteins of other mycobacterial species. Specifically, these sequences showed 99% homology with M. avium 85-complex protein sequences. The multiple homology analysis of these sequences revealed that variations occur at only certain amino acid positions and this is true with all other 85-complex protein sequences of mycobacteria. However, the proposed three conserved regions involved in fibronectin binding in other mycobacteria were observed in N-terminal regions 85A, B and C of M. avium subsp. paratuberculosis.
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