myctu-Rv2485c

 
Mycobacterium tuberculosis, Mycobacterium bovis, Rv2485c Probable lipase lipQ

Comment
There are more than 1000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains


Relationship
Family BD-FAE
Block H
Mycobacterium tuberculosis position in NCBI Life Tree :
N link to NCBI taxonomic web page and E link to ESTHER gene locus found in this strain.
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Corynebacteriales: N E > Mycobacteriaceae: N E > Mycobacterium: N E > Mycobacterium tuberculosis complex: N E > Mycobacterium tuberculosis: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic



>3 Genbank links 9 more: AL021246, BX248342, AE000516
>3 UniProt links 1 more: A1KLH9, A2VKK5, A5U5I1
1 Ncbi-nid : 3261507
1 Ncbi-pid : 2791525
3 UniProtTrembl : O53210, A5U5I1, I6Y9F7
3 Interpro : O53210, A5U5I1, I6Y9F7
3 Prodom : O53210, A5U5I1, I6Y9F7
3 Pfam : O53210, A5U5I1, I6Y9F7
3 PIRSF : O53210, A5U5I1, I6Y9F7
3 SUPERFAM : O53210, A5U5I1, I6Y9F7
3 QuickSwissBlast : O53210, A5U5I1, I6Y9F7
 
Sequence
Graphical view for this peptide sequence: myctu-Rv2485c
Colored MSA for BD-FAE (raw)
MHIASVTSRCSRAGAEALRQGAQLAADARDTCRAGALLLRGSPCAIGWVA
GWLSAEFPARVVTGHALSRISPRSIGRFGTSWAAQRADQILHAALVDAFG
PDFRDLVWHPTGEQSEAARRSGLLNLPHIPGPHRRYAAQTSDIPYGPGGR
ENLLDIWRRPDLAPGRRAPVLIQVPGGAWTINGKRPQAYPLMSRMVELGW
ICVSINYSKSPRCTWPAHIVDVKRAIAWVRENIADYGGDPDFITITGGSA
GAHLAALAALSANDPALQPGFESADTAVQAAAPYYGVYDLTNAENMHEMM
MPFLEHFVMRSRYVDNPGLFKAASPISYVHSEAPPFFVLHGEKDPMVPSA
QSRAFSAALRDAGAATVSYAELPNAHHAFDLAATVRSRMVAEAVSDFLGV
IYGRRMGARKGSLALSSPPAS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MHIASVTSRCSRAGAEALRQGAQLAADARDTCRAGALLLRGSPCAIGWVA
GWLSAEFPARVVTGHALSRISPRSIGRFGTSWAAQRADQILHAALVDAFG
PDFRDLVWHPTGEQSEAARRSGLLNLPHIPGPHRRYAAQTSDIPYGPGGR
ENLLDIWRRPDLAPGRRAPVLIQVPGGAWTINGKRPQAYPLMSRMVELGW
ICVSINYSKSPRCTWPAHIVDVKRAIAWVRENIADYGGDPDFITITGGSA
GAHLAALAALSANDPALQPGFESADTAVQAAAPYYGVYDLTNAENMHEMM
MPFLEHFVMRSRYVDNPGLFKAASPISYVHSEAPPFFVLHGEKDPMVPSA
QSRAFSAALRDAGAATVSYAELPNAHHAFDLAATVRSRMVAEAVSDFLGV
IYGRRMGARKGSLALSSPPAS

no DNA




References
6 more
    Title: The immunosuppressive effects of a novel recombinant LipQ (Rv2485c) protein of Mycobacterium tuberculosis on human macrophage cell lines
    Kumar A, Manisha, Sangha GK, Shrivastava A, Kaur J
    Ref: Microb Pathog, 107:361, 2017 : PubMed

            

    Title: The complete genome sequence of Mycobacterium bovis
    Garnier T, Eiglmeier K, Camus JC, Medina N, Mansoor H, Pryor M, Duthoy S, Grondin S, Lacroix C and Hewinson RG <12 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 100:7877, 2003 : PubMed

            

    Title: An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae
    Philipp WJ, Poulet S, Eiglmeier K, Pascopella L, Balasubramanian V, Heym B, Bergh S, Bloom BR, Jacobs WR, Jr., Cole ST
    Ref: Proc Natl Acad Sci U S A, 93:3132, 1996 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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