Gene_Locus Report

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Gene_locus Report for: myctu-ym23

Mycobacterium tuberculosis Mycobacterium bovis hypothetical 55.1 kda protein MT2281 rv2223c caeB precursor

Comment
There are more than 1000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains


Relationship
Family|AlphaBeta_hydrolase
Block| X
Position in NCBI Life Tree|Mycobacterium tuberculosis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Corynebacteriales: N E > Mycobacteriaceae: N E > Mycobacterium: N E > Mycobacterium tuberculosis complex: N E > Mycobacterium tuberculosis: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 1 more: Z70692, BX248341, BX842579
>3 UniProt links 1 more: P9WHR4, P9WHR5, P65822
>3 UniProt links 1 more: P9WHR4, P9WHR5, P65822
>3 Interpro links 1 more: P9WHR4, P9WHR5, P65822
>3 Prodom links 1 more: P9WHR4, P9WHR5, P65822
>3 Pfam links 1 more: P9WHR4, P9WHR5, P65822
>3 PIRSF links 1 more: P9WHR4, P9WHR5, P65822
>3 SUPERFAM links 1 more: P9WHR4, P9WHR5, P65822
Sequence
Graphical view for this peptide sequence: myctu-ym23
Colored MSA for AlphaBeta_hydrolase (raw)
MAAMWRRRPLSSALLSFGLLLGGLPLAAPPLAGATEEPGAGQTPGAPVVA
PQQSWNSCREFIADTSEIRTARCATVSVPVDYDQPGGTQAKLAVIRVPAT
GQRFGALLVNPGGPGASAVDMVAAMAPAIADTDILRHFDLVGFDPRGVGH
STPALRCRTDAEFDAYRRDPMADYSPAGVTHVEQVYRQLAQDCVDRMGFS
FLANIGTASVARDMDMVRQALGDDQINYLGYSYGTELGTAYLERFGTHVR
AMVLDGAIDPAVSPIEESISQMAGFQTAFNDYAADCARSPACPLGTDSAQ
WVNRYHALVDPLVQKPGKTSDPRGLSYADATTGTINALYSPQRWKYLTSG
LLGLQRGSDAGDLLVLADDYDGRDADGHYSNDQDAFNAVRCVDAPTPADP
AAWVAADQRIRQVAPFLSYGQFTGSAPRDLCALWPVPATSTPHPAAPAGA
GKVVVVSTTHDPATPYQSGVDLARQLGAPLITFDGTQHTAVFDGNQCVDS
AVMHYFLDGTLPPTSLRCAP
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MAAMWRRRPLSSALLSFGLLLGGLPLAAPPLAGATEEPGAGQTPGAPVVA
PQQSWNSCREFIADTSEIRTARCATVSVPVDYDQPGGTQAKLAVIRVPAT
GQRFGALLVNPGGPGASAVDMVAAMAPAIADTDILRHFDLVGFDPRGVGH
STPALRCRTDAEFDAYRRDPMADYSPAGVTHVEQVYRQLAQDCVDRMGFS
FLANIGTASVARDMDMVRQALGDDQINYLGYSYGTELGTAYLERFGTHVR
AMVLDGAIDPAVSPIEESISQMAGFQTAFNDYAADCARSPACPLGTDSAQ
WVNRYHALVDPLVQKPGKTSDPRGLSYADATTGTINALYSPQRWKYLTSG
LLGLQRGSDAGDLLVLADDYDGRDADGHYSNDQDAFNAVRCVDAPTPADP
AAWVAADQRIRQVAPFLSYGQFTGSAPRDLCALWPVPATSTPHPAAPAGA
GKVVVVSTTHDPATPYQSGVDLARQLGAPLITFDGTQHTAVFDGNQCVDS
AVMHYFLDGTLPPTSLRCAP


References
5 more
    Title: Rv2223c, an acid inducible carboxyl-esterase of Mycobacterium tuberculosis enhanced the growth and survival of Mycobacterium smegmatis
    Maan P, Kaur J
    Ref: Future Microbiol, 14:1397, 2019 : PubMed

            

    Title: Characterization of a novel cell wall-anchored protein with carboxylesterase activity required for virulence in Mycobacterium tuberculosis
    Lun S, Bishai WR
    Ref: Journal of Biological Chemistry, 282:18348, 2007 : PubMed

            

    Title: The complete genome sequence of Mycobacterium bovis
    Garnier T, Eiglmeier K, Camus JC, Medina N, Mansoor H, Pryor M, Duthoy S, Grondin S, Lacroix C and Hewinson RG <12 more author(s)>
    Ref: Proc Natl Acad Sci U S A, 100:7877, 2003 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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