(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) > cellular organisms: NE > Bacteria: NE > Proteobacteria: NE > Betaproteobacteria: NE > Nitrosomonadales: NE > Nitrosomonadaceae: NE > Nitrosomonas: NE > Nitrosomonas eutropha: NE
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) Nitrosomonas eutropha C71: N, E.
Nitrosomonas eutropha C91: N, E.
LegendThis sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA MITKKSYRSHETVRPEAAEEGGTADSPANSFGFFPATGLPQVHAITEYAV DTWQRSVLYADVMRQRGNQYQAHLTEEVPNVLDFPSEVILSGQDLPRPVN YWLVRIVPPKDKPTDNMKRPFVVIDPRAGHGPGIGGFKVDSEIGVVIDAG HPCYFIGFLPDPVPEQTIEDVMHAQAAFMEKVLALHPCREGKPAVIGNCQ AGWQILMTAAMRPELFGPIIVAGAPLSYWAGWRGRDPMRYTAGLLGGSWL TALTSDIGGGRFDGAWLVQNFENLNPANTLWNKQYHLYSNIDTEAQRYLG FEKYWGGYVFLNDVEMQYIVDNLFIGNRLATAELITSDGERIDLRNIRSP IVVFCSYGDNITPPPQALGWITDLYGDDEDVLTHDQTIVYATHDSVGHLG IFVSGAVSRKEHHKFTTNIDLIDVLPAGTYRATIAGDAPKNSGPSIGNYE LSIEPTRMVDLRDIVQPDPESDRRFAAVAQLSKTNLALYRQFVQPWVRQA VTPQTAHWVQTMHPLRLSYEWWSDHNPLAPLVADTAKKIREQRAPISEDN PFLQFQGIWSDAIVKTLNLWRDARDDACEKAFEWTYSSPWVQALAGQSGD DEPMRQRPSVTPEHRAFVAQEIEELRDAVTEGGAIEAGIRAVFYIHRFCS SIDERRANLTLELHQPNCDRGFDMDSFRAIVRRQANIMRLDTDAAITALP QLLAHEEPGRIREVARTLERLRSIGPLSTAEETSLTQMLDVFEVAATAQD TVLS
Analysis of the structure and inventory of the genome of Nitrosomonas eutropha C91 revealed distinctive features that may explain the adaptation of N. eutropha-like bacteria to N-saturated ecosystems. Multiple gene-shuffling events are apparent, including mobilized and replicated transposition, as well as plasmid or phage integration events into the 2.66 Mbp chromosome and two plasmids (65 and 56 kbp) of N. eutropha C91. A 117 kbp genomic island encodes multiple genes for heavy metal resistance, including clusters for copper and mercury transport, which are absent from the genomes of other ammonia-oxidizing bacteria (AOB). Whereas the sequences of the two ammonia monooxygenase and three hydroxylamine oxidoreductase gene clusters in N. eutropha C91 are highly similar to those of Nitrosomonas europaea ATCC 19718, a break of synteny in the regions flanking these clusters in each genome is evident. Nitrosomonas eutropha C91 encodes four gene clusters for distinct classes of haem-copper oxidases, two of which are not found in other aerobic AOB. This diversity of terminal oxidases may explain the adaptation of N. eutropha to environments with variable O(2) concentrations and/or high concentrations of nitrogen oxides. As with N. europaea, the N. eutropha genome lacks genes for urease metabolism, likely disadvantaging nitrosomonads in low-nitrogen or acidic ecosystems. Taken together, this analysis revealed significant genomic variation between N. eutropha C91 and other AOB, even the closely related N. europaea, and several distinctive properties of the N. eutropha genome that are supportive of niche specialization.
