Gene_Locus Report

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Gene_locus Report for: octvu-a0a075d677

Octopus vulgaris (Common octopus). Acetylcholinesterase

Relationship
Family|ACHE
Block| C
Position in NCBI Life Tree|Octopus vulgaris
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Lophotrochozoa: N E > Mollusca: N E > Cephalopoda: N E > Coleoidea: N E > Neocoleoidea: N E > Octopodiformes: N E > Octopoda: N E > Incirrata: N E > Octopodidae: N E > Octopus: N E > Octopus vulgaris: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : KC733826
1 UniProt : A0A075D677
1 UniProt : A0A075D677
1 Interpro : A0A075D677
1 Pfam : A0A075D677
1 PIRSF : A0A075D677
1 SUPERFAM : A0A075D677
Sequence
Graphical view for this peptide sequence: octvu-a0a075d677
Colored MSA for ACHE (raw)
MEGLKYIFIIFLLKIYVHAEDPIIQTNKGKIKGSTVLIQGVEVDVFLGIP
FARPPVGNLRFRHPQPARPWSGVKETKKYVSSCVQVKDTTFGDFEGAEMW
NPNTVMSEDCLYLNIWAPSEARKSRSQLATMIWIFGGAFMSGSSTLDIYD
GRWLAASENVIVASLNYRLGPFGFLSLNNVRAPGNMGLLDQTLAIQWIRD
NILSFGGDPKKLTLFGESAGSGSVSLHVVSPLSQRLFRNAIMMSGSATAT
WATVPVEKNIERAKAMADFLKCPTENTTSMIDCFLEADAHKLANAQFHNL
DSFLPYTLSPIVDGAFLTQKPIESLKNEPQKKDVLLGYVTNEGTYFLIYD
LPKYFSLKGTVPINKSTAGKLINKVIAPLRANSVQLDLISYLYGSHVYGS
SETDKYRYILDQASGDVKFKCPVIEFAQEYSKHAKVYMYSFEFRSRLNPW
PEWAGVMHGYEIEFLFAQTLSGKNYSKEGNLVTKRTTSLFANFSKSGNPN
NGECSDCSNEPWPEFTPRNQKYLVIDDKPTLETRENYMNNICGFWSDFFP
GLTDHKCPEMASGSQTFHWRTLTSFASIFCSLMLSFNILF
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MEGLKYIFIIFLLKIYVHAEDPIIQTNKGKIKGSTVLIQGVEVDVFLGIP
FARPPVGNLRFRHPQPARPWSGVKETKKYVSSCVQVKDTTFGDFEGAEMW
NPNTVMSEDCLYLNIWAPSEARKSRSQLATMIWIFGGAFMSGSSTLDIYD
GRWLAASENVIVASLNYRLGPFGFLSLNNVRAPGNMGLLDQTLAIQWIRD
NILSFGGDPKKLTLFGESAGSGSVSLHVVSPLSQRLFRNAIMMSGSATAT
WATVPVEKNIERAKAMADFLKCPTENTTSMIDCFLEADAHKLANAQFHNL
DSFLPYTLSPIVDGAFLTQKPIESLKNEPQKKDVLLGYVTNEGTYFLIYD
LPKYFSLKGTVPINKSTAGKLINKVIAPLRANSVQLDLISYLYGSHVYGS
SETDKYRYILDQASGDVKFKCPVIEFAQEYSKHAKVYMYSFEFRSRLNPW
PEWAGVMHGYEIEFLFAQTLSGKNYSKEGNLVTKRTTSLFANFSKSGNPN
NGECSDCSNEPWPEFTPRNQKYLVIDDKPTLETRENYMNNICGFWSDFFP
GLTDHKCPEMASGSQTFHWRTLTSFASIFCSLMLSFNILF


Reference
    Title: Identification and Expression of Acetylcholinesterase in Octopus vulgaris Arm Development and Regeneration: a Conserved Role for ACHE?
    Fossati SM, Candiani S, Nodl MT, Maragliano L, Pennuto M, Domingues P, Benfenati F, Pestarino M, Zullo L
    Ref: Molecular Neurobiology, 52:45, 2015 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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