phano-phmG

Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum) Hydrolase phmG

Comment

Hydrolyase\; part of the gene cluster that mediates the biosynthesis of the mycotoxins phomacins, leucine-derived cytochalasans with potent actin polymerization-inhibitory activities and monocot-specific antigerminative activities

Relationship

Family : Duf_1100-S

Block : X

Position in NCBI Life Tree : Parastagonospora nodorum

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MTNSSPPFST IHQFFPGNTF LNFESVRILS TAPYGGCDAA EFLTAIAAIN PKDPQTWADA WSHMAHLAET MAEEALSRGD VVAARDGFLR ASSYTRASGY LYINGPTLDE HHPLAFEISK KVQSLFRRAL PFLDCDVHVV EIPYVVDSPE RKEVMLPGYL YLPNAQHRLP DGKIPVLLNT GGADSVQEEL YYIHPQGGHT RGYAVLTFEG PGQGIVLREH GLHMRPDWEV TGWKGYSSTL KREVGVELDL DRIAVAGASM GGYYALRAAK DSRIKACVAI DPFYDMWDFG TKHISGLFMS AWTGGWIGDD WVDRIIRLGM RTNFQLRWEV GVTAAFWGIA SPAKILKEMS KYSLKGGYLE KVQCPVLVTG AGKSLYFDTE EHTMKVFDDL GHLEERWRRV WMPNRPEEGG LQAKIGAFGL ANMKAYGFLD EVFGIRRVTV ES

References

Title : Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans - Zhang_2021_Chemistry_10_3106
Author(s) : Zhang H , Hantke V , Bruhnke P , Skellam E , Cox RJ
Ref : Chemistry , 10 :3106 , 2021
Abstract : Zhang_2021_Chemistry_10_3106
ESTHER : Zhang_2021_Chemistry_10_3106
PubMedSearch : Zhang_2021_Chemistry_10_3106
PubMedID: 33146923
Gene_locus related to this paper: phano-phmG , aspcl-CCSE , aspfu-psoB , mago7-ORFZB , maggr-pyie

Title : Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum - Li_2020_ACS.Chem.Biol_15_226
Author(s) : Li H , Wei H , Hu J , Lacey E , Sobolev AN , Stubbs KA , Solomon PS , Chooi YH
Ref : ACS Chemical Biology , 15 :226 , 2020
Abstract : Li_2020_ACS.Chem.Biol_15_226
ESTHER : Li_2020_ACS.Chem.Biol_15_226
PubMedSearch : Li_2020_ACS.Chem.Biol_15_226
PubMedID: 31815421
Gene_locus related to this paper: phano-phmG

Title : Investigating the Function of Cryptic Cytochalasan Cytochrome P450 Monooxygenases Using Combinatorial Biosynthesis - Wang_2019_Org.Lett_21_8756
Author(s) : Wang C , Becker K , Pfutze S , Kuhnert E , Stadler M , Cox RJ , Skellam E
Ref : Org Lett , 21 :8756 , 2019
Abstract : Wang_2019_Org.Lett_21_8756
ESTHER : Wang_2019_Org.Lett_21_8756
PubMedSearch : Wang_2019_Org.Lett_21_8756
PubMedID: 31644300
Gene_locus related to this paper: phano-phmG , aspcl-CCSE , aspfu-psoB , mago7-ORFZB , maggr-pyie

Title : Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae - Song_2015_Chem.Sci_6_4837
Author(s) : Song Z , Bakeer W , Marshall JW , Yakasai AA , Khalid RM , Collemare J , Skellam E , Tharreau D , Lebrun MH , Lazarus CM , Bailey AM , Simpson TJ , Cox RJ
Ref : Chem Sci , 6 :4837 , 2015
Abstract : Song_2015_Chem.Sci_6_4837
ESTHER : Song_2015_Chem.Sci_6_4837
PubMedSearch : Song_2015_Chem.Sci_6_4837
PubMedID: 29142718
Gene_locus related to this paper: phano-phmG , aspcl-CCSE , aspfu-psoB , mago7-ORFZB