Gene_Locus Report

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Gene_locus Report for: proac-q6ab58

Propionibacterium acnes putative hydrolase

Comment
Other strains: Propionibacterium acnes (strains: HL002PA1; HL086PA1; HL078PA1; HL056PA1; HL083PA2; HL030PA2; HL043PA1; SK137; HL025PA1; HL059PA1; HL005PA1; HL072PA2; HL110PA3; HL110PA4; SK187; HL092PA1; HL082PA1; HL097PA1; HL050PA2; HL110PA1; HL059PA2; HL074PA1; HL027PA1; HL046PA1; HL005PA3; HL067PA1; HL036PA1; HL002PA3; HL036PA2; HL096PA2; HL087PA2; HL087PA3; HL013PA2; HL027PA2; HL050PA3; HL053PA1; HL007PA1; HL046PA2; HL045PA1; HL053PA2; HL043PA2; HL050PA1; J139; HL103PA1; HL110PA2; HL013PA1; HL063PA1; HL037PA1; HL038PA1; HL063PA2; HL005PA4; HL030PA1; HL083PA1; HL002PA2; HL072PA1; HL082PA2; J165; HL060PA1; HL096PA3; HL036PA3; HL005PA2; HL001PA1


Relationship
Family|Tiancimycin-TnmK-Tripeptidase-HIP
Block| X
Position in NCBI Life Tree|Propionibacterium acnes
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Propionibacteriales: N E > Propionibacteriaceae: N E > Cutibacterium: N E > Cutibacterium acnes: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : AE017283
3 UniProt : Q6AB58, E6D7U2, D1Y9N2
3 UniProt : Q6AB58, E6D7U2, D1Y9N2
3 Interpro : Q6AB58, E6D7U2, D1Y9N2
3 Pfam : Q6AB58, E6D7U2, D1Y9N2
3 PIRSF : Q6AB58, E6D7U2, D1Y9N2
3 SUPERFAM : Q6AB58, E6D7U2, D1Y9N2
Sequence
Graphical view for this peptide sequence: proac-q6ab58
Colored MSA for Tiancimycin-TnmK-Tripeptidase-HIP (raw)
MTPRVSRRRMFVSALMASSLFAVTACTSAGSRPPQSASVSRQSASHKPSA
SPSVTASVVPAQDKVDTNPPVASFDPKAHALMEGPQSPDRQAMHPARDNK
PFSKAPAGKGTNRYLSRKISWHDCGTFQCADIPVPLDWDNPDGPAITLAL
KRKPAEGAAKATLFINPGGPGGSGQDMVSSFQSSAFPDHDVIGWDLRGTG
ASTHVNCGPAKTMDGLFSLDASPDNEAEWNGLIRGTRDFARSCRAYSGQL
LDHVSTIDTARDLDYLRYLVGNKKLDYLGVSYGTFLGATYAELYPGRVGH
MVLDSTVNITNHDTVSQAVGFDRAFGDFAQWCANRGNRCALGTSAAEIRK
ATLNFLDRLDAHPMKVAGRELTQSLAATGIALFLYSGKQAYSYLTAALVG
AMKDGNGGYLLTASDYLNGRGKDGQWETIASAFPAISCLDQADFGLKHAR
QEWPHEIAKAPTLGKALGVAPICEVWTARPAPQLYLTARGAAPILVLGAT
GDPATPYEQATWMAGQLKSGVLLTWRGSGHSAWELGNQCVKKAVEGYVND
GKTPKDNTVC
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MTPRVSRRRMFVSALMASSLFAVTACTSAGSRPPQSASVSRQSASHKPSA
SPSVTASVVPAQDKVDTNPPVASFDPKAHALMEGPQSPDRQAMHPARDNK
PFSKAPAGKGTNRYLSRKISWHDCGTFQCADIPVPLDWDNPDGPAITLAL
KRKPAEGAAKATLFINPGGPGGSGQDMVSSFQSSAFPDHDVIGWDLRGTG
ASTHVNCGPAKTMDGLFSLDASPDNEAEWNGLIRGTRDFARSCRAYSGQL
LDHVSTIDTARDLDYLRYLVGNKKLDYLGVSYGTFLGATYAELYPGRVGH
MVLDSTVNITNHDTVSQAVGFDRAFGDFAQWCANRGNRCALGTSAAEIRK
ATLNFLDRLDAHPMKVAGRELTQSLAATGIALFLYSGKQAYSYLTAALVG
AMKDGNGGYLLTASDYLNGRGKDGQWETIASAFPAISCLDQADFGLKHAR
QEWPHEIAKAPTLGKALGVAPICEVWTARPAPQLYLTARGAAPILVLGAT
GDPATPYEQATWMAGQLKSGVLLTWRGSGHSAWELGNQCVKKAVEGYVND
GKTPKDNTVC


Reference
    Title: The complete genome sequence of Propionibacterium acnes, a commensal of human skin
    Bruggemann H, Henne A, Hoster F, Liesegang H, Wiezer A, Strittmatter A, Hujer S, Durre P, Gottschalk G
    Ref: Science, 305:671, 2004 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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ESTHER Home Page and ACEDB Home Page
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