1. Home
  2. Gene Locus
  3. pseae-PA2927

pseae-PA2927

Pseudomonas aeruginosa hypothetical protein pa2927 PaPlaB

Comment

A major cell-associated hemolytic phospholipase A (PlaB). PaPlaB preferentially hydrolyzes long-chain fatty acid substrates containing 12 or more carbon atoms. PlaB shows concentration-dependent phospholipase inactivation by tetramerization which may be a mechanism for self-protection.PaPlaB is inhibited by Paraoxon but not PMSF. Other strains: Pseudomonas aeruginosa PAO1-VE13\; PAO1-VE2\; PAO581\; ATCC 15692 \/ PAO1 \/ 1C \/ PRS 101 \/ LM 12228\; PAO579\; MPAO1\/P2\; MPAO1\/P1\; BL01\; CF18\; 19660\; 2192\; UCBPP-PA14\; NCGM2.S1\; 39016\; MH27\; JJ692\; BL20\; BL22\; 6077\; U2504\; BWHPSA006\; BL08\; BL09\; BL14\; BL16\; BL17\; PA14\; CI27\; sp. 2_1_26\; BL18\; VRFPA03\; VRFPA07\; VRFPA08\; MSH10\; BL02\; BL12\; BL13\; BL25\; MSH3\; BWHPSA005\; BWHPSA023\; BWHPSA024\; BL04\; BL15\; C20\; C23\; VRFPA04\; MSH-10\; PA45\; 18A\; NCMG1179\; YL84\; SCV20265\; LES431\; MTB-1\; RP73\; B136-33\; DK2\; M18\; LESB58\; DHS29\; VRFPA06\; DHS01\; HB15\; CF127\; CF27\; CF5\; S54485\; BWHPSA007\; BWHPSA009\; BWHPSA010\; BWHPSA008\; BWHPSA016\; BL03\; BL05\; BL21\; BL23\; BL24\; M8A.4\; M8A.3\; 62\; X24509\; X24509\; UDL\; X13273\; S35004\; BWHPSA001\; BWHPSA002\; BWHPSA003\; BWHPSA011\; BWHPSA013\; BWHPSA017\; BWHPSA018\; BWHPSA019\; BWHPSA022\; BWHPSA025\; BWHPSA026\; BWHPSA027\; BWHPSA028\; BL07\; BL10\; BL19\; M8A.2\; M8A.1\; M9A.1\; C48\; C51\; CF77\; C52\; HB13\; WC55\; PAK\; Stone 130\; PA21_ST175\; ATCC 700888\; ATCC 14886\; CIG1\; PADK2_CF510\; PA1R\; PA1\; c7447m\; BL06\; BWHPSA004\; BWHPSA012\; BWHPSA014\; BWHPSA020\; BWHPSA021\; BL11\; C40\; C41\; CF614\; sp. P179\; E2\; BWHPSA015\; ATCC 25324\; PA7\; MH38\; PA38182

Relationship

Family : PlaB

Block : X

Position in NCBI Life Tree : Pseudomonas aeruginosa

Molecular evidence

No mutation

No structure

No kinetic

No disease

No inhibitor

Database

AE004719 CP006832 CP006831 CP006705 AE004091 ALOF01000013 AHKN01000073 AHKM01000030 AXPZ01000005 AXRN01000001 AXRF01000001 CH482384 CP000438 AP012280 AEEX01000113 CBTR010000011 AXRH01000002 AXPG01000004 AXPE01000003 AXRE01000002 AXRG01000003 AXQW01000004 AXPS01000003 AXPR01000009 AXPM01000002 AXPK01000001 AXPJ01000006 ASWV01000017 AKZG01000058 ACWU01000034 AXPI01000001 ATNK01000121 AZBO01000130 AZHU01000150 AXRP01000003 AXPY01000009 AXPO01000002 AXPN01000005 AXPB01000001 AXRQ01000013 AXQX01000008 AXQF01000007 AXQE01000007 AXPW01000001 AXPL01000002 AXOV01000006 AXOU01000006 AWWZ01000011 ASWW01000003 APMD01000031 CAQZ01000093 DF126593 CP007147 CP006931 CP006937 CP006853 CP006245 CP004061 CP003149 CP002496 FM209186 AYON01000120 AYSK01000022 AYNE01000049 AEVW03000001 AXRO01000001 AXRM01000007 AXRL01000004 AXRI01000014 AXQV01000019 AXQT01000006 AXQS01000008 AXQU01000017 AXQM01000015 AXPX01000003 AXPV01000002 AXPF01000005 AXPD01000025 AXPC01000016 AXOX01000011 AXOY01000013 AXRS01000013 AXRK01000002 AXRJ01000009 AXRC01000002 AXRD01000022 AXRB01000005 AXRA01000002 AXQZ01000004 AXQR01000002 AXQP01000008 AXQL01000010 AXQK01000018 AXQJ01000011 AXQG01000010 AXQD01000001 AXQC01000003 AXQB01000001 AXQA01000002 AXPT01000009 AXPQ01000005 AXPH01000003 AXOZ01000001 AXPA01000009 AXOW01000003 AXOR01000007 AXOQ01000008 AXOO01000001 AXOP01000015 AEVV03000003 ATAQ01000001 ASWU01000008 AQFN01000012 AOIH01000012 AKZF01000176 AKZD01000091 AKBD01000194 AJHI01000063 CP004055 CP004054 CP006728 AXPU01000003 AXQY01000004 AXQQ01000004 AXQO01000004 AXQI01000003 AXQH01000002 AXPP01000006 AXOT01000003 AXOS01000011 AXON01000002 AQFO01000014 AKZH01000061 AXRR01000003 AXQN01000003 AKZE01000309 CP000744 CBTQ010000051 HG530068

Sequence

Peptide

MPRSIVIVHG WSDDSKSFRR LAEQLEAWFG SAPTQIRLTD WISLQDDVTY ADLAAALDRA WTAQGLSRAP RTVDVVVHST GTLVLRDWLT RHFDPASAPV KRFLMLAPAN FGSPLAHKGR SFIGRVLKGW NRFVGQTGTQ VLKGLELGSP YSWQLAERDL FGAEAWYGAD RLLATVLVGN VGYSGVEAIA NEAGSDGTVR IATANLNACR LSLELDVRQR ARPGWRLEES RGEIAFAIVD GENHASVALK DRGPKNPHTL ELIRAALEVE DADYRSSGAS FPWQRRIDQL DPGIERRSPR YLNLVSHVCD DLDQEVRDYF IQFFRKLNSD RRFEQRFYEQ VIADVHPYED NPAYRSLYLS IESLDDLLAG FAVDTLSLSV SAQPPFDPPR QPVGYTAVGP GDSEGLAIPL AQVPRFLAAH RTLLLRIRLT RLVDSGVFVF RNP

References

Title : A phospholipase B from Pseudomonas aeruginosa with activity towards endogenous phospholipids affects biofilm assembly - Weiler_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159101
Author(s) : Weiler AJ , Spitz O , Gudzuhn M , Schott-Verdugo SN , Kamel M , Thiele B , Streit WR , Kedrov A , Schmitt L , Gohlk H , Kovacic F , Gohlke H
Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , 1867 :159101 , 2022
Abstract : Weiler_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159101
ESTHER : Weiler_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159101
PubMedSearch : Weiler_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159101
PubMedID: 35063652
Gene_locus related to this paper: pseae-PA2927

Title : Draft Genome Sequence of VIM-2-Producing Multidrug-Resistant Pseudomonas aeruginosa ST175, an Epidemic High-Risk Clone - Viedma_2013_Genome.Announc_1_e0011213
Author(s) : Viedma E , Juan C , Otero JR , Oliver A , Chaves F
Ref : Genome Announc , 1 :e0011213 , 2013
Abstract : Viedma_2013_Genome.Announc_1_e0011213
ESTHER : Viedma_2013_Genome.Announc_1_e0011213
PubMedSearch : Viedma_2013_Genome.Announc_1_e0011213
PubMedID: 23580706
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Genome Sequence of Pseudomonas aeruginosa PA45, a Highly Virulent Strain Isolated from a Patient with Bloodstream Infection - Segata_2013_Genome.Announc_1_E00289
Author(s) : Segata N , Ballarini A , Jousson O
Ref : Genome Announc , 1 : , 2013
Abstract : Segata_2013_Genome.Announc_1_E00289
ESTHER : Segata_2013_Genome.Announc_1_E00289
PubMedSearch : Segata_2013_Genome.Announc_1_E00289
PubMedID: 23704188
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Complete Genome Sequence of Persistent Cystic Fibrosis Isolate Pseudomonas aeruginosa Strain RP73 - Jeukens_2013_Genome.Announc_1_e00568
Author(s) : Jeukens J , Boyle B , Bianconi I , Kukavica-Ibrulj I , Tummler B , Bragonzi A , Levesque RC
Ref : Genome Announc , 1 :e00568 , 2013
Abstract : Jeukens_2013_Genome.Announc_1_e00568
ESTHER : Jeukens_2013_Genome.Announc_1_e00568
PubMedSearch : Jeukens_2013_Genome.Announc_1_e00568
PubMedID: 23908295
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Draft Genome Sequence of a Mucoid Isolate of Pseudomonas aeruginosa Strain C7447m from a Patient with Cystic Fibrosis - Yin_2013_Genome.Announc_1_e00837
Author(s) : Yin Y , Withers TR , Johnson SL , Yu HD
Ref : Genome Announc , 1 : , 2013
Abstract : Yin_2013_Genome.Announc_1_e00837
ESTHER : Yin_2013_Genome.Announc_1_e00837
PubMedSearch : Yin_2013_Genome.Announc_1_e00837
PubMedID: 24115552
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA3695 , pseae-PA5080

Title : Whole-genome sequences of five oyster-associated bacteria show potential for crude oil hydrocarbon degradation - Chauhan_2013_Genome.Announc_1_e00802
Author(s) : Chauhan A , Green S , Pathak A , Thomas J , Venkatramanan R
Ref : Genome Announc , 1 : , 2013
Abstract : Chauhan_2013_Genome.Announc_1_e00802
ESTHER : Chauhan_2013_Genome.Announc_1_e00802
PubMedSearch : Chauhan_2013_Genome.Announc_1_e00802
PubMedID: 24092793
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA3695 , pseae-PA5080 , stema-t5kff6 , 9mico-t5km21 , 9mico-t5ky94 , 9mico-t5k5a3 , 9mico-t5kmk8 , pseac-u3h334 , psest-u3hv50 , strmk-b2fpy9 , pseae-q9i252 , pseac-u3hfm5 , psest-u3hma4 , pseac-u3hhm8 , stema-t5kck8 , pseac-u3h4w0 , psest-u3hqe0 , 9mico-t5kbd8

Title : Draft Genome Sequences of Two Alginate-Overproducing Variants of Pseudomonas aeruginosa, PAO1-VE2 and PAO1-VE13 - Yin_2013_Genome.Announc_1_e01031
Author(s) : Yin Y , Withers TR , Niles RM , Johnson SL , Yu HD
Ref : Genome Announc , 1 : , 2013
Abstract : Yin_2013_Genome.Announc_1_e01031
ESTHER : Yin_2013_Genome.Announc_1_e01031
PubMedSearch : Yin_2013_Genome.Announc_1_e01031
PubMedID: 24336371
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA3695 , pseae-PA5080

Title : Draft Genome Sequence of a Stable Mucoid Strain of Pseudomonas aeruginosa PAO581 with a mucA25 Mutation - Yin_2013_Genome.Announc_1_e00834
Author(s) : Yin Y , Withers TR , Govan JR , Johnson SL , Yu HD
Ref : Genome Announc , 1 : , 2013
Abstract : Yin_2013_Genome.Announc_1_e00834
ESTHER : Yin_2013_Genome.Announc_1_e00834
PubMedSearch : Yin_2013_Genome.Announc_1_e00834
PubMedID: 24115549
Gene_locus related to this paper: pseae-PA2927 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak - Olivas_2012_PLoS.One_7_e44326
Author(s) : Olivas AD , Shogan BD , Valuckaite V , Zaborin A , Belogortseva N , Musch M , Meyer F , Trimble WL , An G , Gilbert J , Zaborina O , Alverdy JC
Ref : PLoS ONE , 7 :e44326 , 2012
Abstract : Olivas_2012_PLoS.One_7_e44326
ESTHER : Olivas_2012_PLoS.One_7_e44326
PubMedSearch : Olivas_2012_PLoS.One_7_e44326
PubMedID: 22952955
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment - Rau_2012_Environ.Microbiol_14_2200
Author(s) : Rau MH , Marvig RL , Ehrlich GD , Molin S , Jelsbak L
Ref : Environ Microbiol , 14 :2200 , 2012
Abstract : Rau_2012_Environ.Microbiol_14_2200
ESTHER : Rau_2012_Environ.Microbiol_14_2200
PubMedSearch : Rau_2012_Environ.Microbiol_14_2200
PubMedID: 22672046
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Strain-dependent diversity in the Pseudomonas aeruginosa quorum-sensing regulon - Chugani_2012_Proc.Natl.Acad.Sci.U.S.A_109_E2823
Author(s) : Chugani S , Kim BS , Phattarasukol S , Brittnacher MJ , Choi SH , Harwood CS , Greenberg EP
Ref : Proc Natl Acad Sci U S A , 109 :E2823 , 2012
Abstract : Chugani_2012_Proc.Natl.Acad.Sci.U.S.A_109_E2823
ESTHER : Chugani_2012_Proc.Natl.Acad.Sci.U.S.A_109_E2823
PubMedSearch : Chugani_2012_Proc.Natl.Acad.Sci.U.S.A_109_E2823
PubMedID: 22988113
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Draft genome sequence for Pseudomonas aeruginosa strain PAO579, a mucoid derivative of PAO381 - Withers_2012_J.Bacteriol_194_6617
Author(s) : Withers TR , Johnson SL , Yu HD
Ref : Journal of Bacteriology , 194 :6617 , 2012
Abstract : Withers_2012_J.Bacteriol_194_6617
ESTHER : Withers_2012_J.Bacteriol_194_6617
PubMedSearch : Withers_2012_J.Bacteriol_194_6617
PubMedID: 23144378
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Genomic analysis and temperature-dependent transcriptome profiles of the rhizosphere originating strain Pseudomonas aeruginosa M18 - Wu_2011_BMC.Genomics_12_438
Author(s) : Wu DQ , Ye J , Ou HY , Wei X , Huang X , He YW , Xu Y
Ref : BMC Genomics , 12 :438 , 2011
Abstract : Wu_2011_BMC.Genomics_12_438
ESTHER : Wu_2011_BMC.Genomics_12_438
PubMedSearch : Wu_2011_BMC.Genomics_12_438
PubMedID: 21884571
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Genome sequence of multidrug-resistant Pseudomonas aeruginosa NCGM1179 - Tada_2011_J.Bacteriol_193_6397
Author(s) : Tada T , Kitao T , Miyoshi-Akiyama T , Kirikae T
Ref : Journal of Bacteriology , 193 :6397 , 2011
Abstract : Tada_2011_J.Bacteriol_193_6397
ESTHER : Tada_2011_J.Bacteriol_193_6397
PubMedSearch : Tada_2011_J.Bacteriol_193_6397
PubMedID: 22038962
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Complete genome sequence of highly multidrug-resistant Pseudomonas aeruginosa NCGM2.S1, a representative strain of a cluster endemic to Japan - Miyoshi-Akiyama_2011_J.Bacteriol_193_7010
Author(s) : Miyoshi-Akiyama T , Kuwahara T , Tada T , Kitao T , Kirikae T
Ref : Journal of Bacteriology , 193 :7010 , 2011
Abstract : Miyoshi-Akiyama_2011_J.Bacteriol_193_7010
ESTHER : Miyoshi-Akiyama_2011_J.Bacteriol_193_7010
PubMedSearch : Miyoshi-Akiyama_2011_J.Bacteriol_193_7010
PubMedID: 22123763
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Draft genome sequences of two Pseudomonas aeruginosa clinical isolates with different antibiotic susceptibilities - Soares-Castro_2011_J.Bacteriol_193_5573
Author(s) : Soares-Castro P , Marques D , Demyanchuk S , Faustino A , Santos PM
Ref : Journal of Bacteriology , 193 :5573 , 2011
Abstract : Soares-Castro_2011_J.Bacteriol_193_5573
ESTHER : Soares-Castro_2011_J.Bacteriol_193_5573
PubMedSearch : Soares-Castro_2011_J.Bacteriol_193_5573
PubMedID: 21705591
Gene_locus related to this paper: pseae-PA1558 , pseae-PA2927 , pseae-PA2949 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Genetic characterization indicates that a specific subpopulation of Pseudomonas aeruginosa is associated with keratitis infections - Stewart_2011_J.Clin.Microbiol_49_993
Author(s) : Stewart RM , Wiehlmann L , Ashelford KE , Preston SJ , Frimmersdorf E , Campbell BJ , Neal TJ , Hall N , Tuft S , Kaye SB , Winstanley C
Ref : J Clin Microbiol , 49 :993 , 2011
Abstract : Stewart_2011_J.Clin.Microbiol_49_993
ESTHER : Stewart_2011_J.Clin.Microbiol_49_993
PubMedSearch : Stewart_2011_J.Clin.Microbiol_49_993
PubMedID: 21227987
Gene_locus related to this paper: pseae-a3kt39 , pseae-clipa , pseae-llipa , pseae-PA0201 , pseae-PA0231 , pseae-PA0308 , pseae-PA0368 , pseae-PA0480 , pseae-PA0543 , pseae-PA0599 , pseae-PA1166 , pseae-PA1239 , pseae-PA1304 , pseae-PA1510 , pseae-PA1558 , pseae-PA1597 , pseae-PA2098 , pseae-PA2302 , pseae-PA2425 , pseae-PA2540 , pseae-PA2682 , pseae-PA2927 , pseae-PA2949 , pseae-PA3301 , pseae-PA3327 , pseae-PA3695 , pseae-PA3859 , pseae-PA4968 , pseae-PA5080 , pseae-PCHC , pseae-PCHF , pseae-PHAC2 , pseae-phaD , pseae-Q8G8C7 , pseae-Q8G8T6 , pseae-q9i252

Title : ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa - Qiu_2008_Microbiology_154_2119
Author(s) : Qiu D , Eisinger VM , Head NE , Pier GB , Yu HD
Ref : Microbiology , 154 :2119 , 2008
Abstract : Qiu_2008_Microbiology_154_2119
ESTHER : Qiu_2008_Microbiology_154_2119
PubMedSearch : Qiu_2008_Microbiology_154_2119
PubMedID: 18599839
Gene_locus related to this paper: pseae-PA2927 , pseae-PA3695 , pseae-PA5080 , pseae-q9i252

Title : Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen - Stover_2000_Nature_406_959
Author(s) : Stover CK , Pham XQ , Erwin AL , Mizoguchi SD , Warrener P , Hickey MJ , Brinkman FS , Hufnagle WO , Kowalik DJ , Lagrou M , Garber RL , Goltry L , Tolentino E , Westbrock-Wadman S , Yuan Y , Brody LL , Coulter SN , Folger KR , Kas A , Larbig K , Lim R , Smith K , Spencer D , Wong GK , Wu Z , Paulsen IT , Reizer J , Saier MH , Hancock RE , Lory S , Olson MV
Ref : Nature , 406 :959 , 2000
Abstract : Stover_2000_Nature_406_959
ESTHER : Stover_2000_Nature_406_959
PubMedSearch : Stover_2000_Nature_406_959
PubMedID: 10984043
Gene_locus related to this paper: pseae-clipa , pseae-CPO , pseae-metx , pseae-PA0201 , pseae-PA0231 , pseae-PA0308 , pseae-PA0368 , pseae-PA0480 , pseae-PA0502 , pseae-PA0543 , pseae-PA0599 , pseae-PA0829 , pseae-PA1166 , pseae-PA1211 , pseae-PA1239 , pseae-PA1291 , pseae-PA1304 , pseae-PA1510 , pseae-PA1558 , pseae-PA1597 , pseae-PA1621 , pseae-PA1622 , pseae-PA1680 , pseae-PA1771 , pseae-PA1888 , pseae-PA1907 , pseae-PA1990 , pseae-PA2086 , pseae-PA2098 , pseae-PA2168 , pseae-PA2302 , pseae-PA2411 , pseae-PA2425 , pseae-PA2451 , pseae-PA2540 , pseae-PA2682 , pseae-PA2689 , pseae-PA2745 , pseae-PA2764 , pseae-PA2927 , pseae-PA2934 , pseae-PA2949 , pseae-PA3053 , pseae-PA3132 , pseae-PA3226 , pseae-PA3301 , pseae-PA3324 , pseae-PA3327 , pseae-PA3429 , pseae-PA3509 , pseae-PA3586 , pseae-PA3628 , pseae-PA3695 , pseae-PA3734 , pseae-PA3829 , pseae-PA3859 , pseae-PA3994 , pseae-PA4008 , pseae-PA4152 , pseae-PA4440 , pseae-PA4968 , pseae-PA5080 , pseae-PA5384 , pseae-PA5513 , pseae-PCHC , pseae-PCHF , pseae-PHAC1 , pseae-PHAC2 , pseae-phaD , pseae-phag , pseae-PVDD , pseae-q9i4b9 , pseae-q9i538 , pseae-rhla , pseae-Y2218 , pseae-q9hyv3 , pseae-q9i252 , pseae-q9i6m9