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pseae-rhla

Pseudomonas aeruginosa, Pseudomonas sp., rhamnosyltransferase 1 subunit a (EC 2.4.1.-) RhlA

Comment

Other strains: Pseudomonas aeruginosa (strains PA7\; UCBPP-PA14\; C3719\; 2192\; LESB58) Pseudomonas sp. DHT2. The biosurfactant 3-(3-hydroxyalkanoyloxy)alkanoic acid (HAA) is the hydrophobic moiety of rhamnolipids and most often consists of two hydroxy fatty acids linked by an ester bond. rhlA genes encoding the acyltransferase responsible for the synthesis of the lipophilic rhamnolipid precursor 3-(3-hydroxyalkanoyloxy)alkanoic acid (HAA) (found only in Betaproteobacteria and Gammaproteobacteria or by horizontal gene transfer in Actinobacteria). Acyl-carrier protein (ACP)-activated hydroxy fatty acids are the preferred substrate for RhlA. The carbon chain lengths of HAAs determine their abilities to foam and emulsify, and their critical micelle concentration (CMC). Their chain lengths are determined by RhlA structure

Relationship

Family : HAA-synthase-thioesterase-RhlA-PhaG

Block : X

Position in NCBI Life Tree : Pseudomonas aeruginosa

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Database

Sequence

Peptide

MRRESLLVSV CKGLRVHVER VGQDPGRSTV MLVNGAMATT ASFARTCKCL AEHFNVVLFD LPFAGQSRQH NPQRGLITKD DEVEILLALI ERFEVNHLVS ASWGGISTLL ALSRNPRGIR SSVVMAFAPG LNQAMLDYVG RAQALIELDD KSAIGHLLNE TVGKYLPQRL KASNHQHMAS LATGEYEQAR FHIDQVLALN DRGYLACLER IQSHVHFING SWDEYTTAED ARQFRDYLPH CSFSRVEGTG HFLDLESKLA AVRVHRALLE HLLKQPEPQR AERAAGFHEM AIGYA

References

Title : RhlA Exhibits Dual Thioesterase and Acyltransferase Activities during Rhamnolipid Biosynthesis - Tang_2023_ACS.Catal_13_5759
Author(s) : Ting Tang T , Fu L , Xie W , Luo Y , Zhang Y , Zhang J , Si T
Ref : ACS Catal , 13 :5759 , 2023
Abstract : Tang_2023_ACS.Catal_13_5759
ESTHER : Tang_2023_ACS.Catal_13_5759
PubMedSearch : Tang_2023_ACS.Catal_13_5759
PubMedID:
Gene_locus related to this paper: pseae-rhla

Title : Exploiting the Natural Diversity of RhlA Acyltransferases for the Synthesis of the Rhamnolipid Precursor 3-(3-Hydroxyalkanoyloxy)Alkanoic Acid - Germer_2020_Appl.Environ.Microbiol_86_e02317
Author(s) : Germer A , Tiso T , Muller C , Behrens B , Vosse C , Scholz K , Froning M , Hayen H , Blank LM
Ref : Applied Environmental Microbiology , 86 : , 2020
Abstract : Germer_2020_Appl.Environ.Microbiol_86_e02317
ESTHER : Germer_2020_Appl.Environ.Microbiol_86_e02317
PubMedSearch : Germer_2020_Appl.Environ.Microbiol_86_e02317
PubMedID: 31924623
Gene_locus related to this paper: pseae-rhla

Title : RhlA converts beta-hydroxyacyl-acyl carrier protein intermediates in fatty acid synthesis to the beta-hydroxydecanoyl-beta-hydroxydecanoate component of rhamnolipids in Pseudomonas aeruginosa - Zhu_2008_J.Bacteriol_190_3147
Author(s) : Zhu K , Rock CO
Ref : Journal of Bacteriology , 190 :3147 , 2008
Abstract : Zhu_2008_J.Bacteriol_190_3147
ESTHER : Zhu_2008_J.Bacteriol_190_3147
PubMedSearch : Zhu_2008_J.Bacteriol_190_3147
PubMedID: 18326581
Gene_locus related to this paper: pseae-rhla

Title : Biosurfactant production and hydrocarbon-degradation by halotolerant and thermotolerant Pseudomonas sp. - Kumar_2008_World.J.Microbiol.Biotechnol_24_1047
Author(s) : Kumar M , Leon V , Materano ADS , Ilzins OA , Luis L
Ref : World J Microbiol Biotechnol , 24 :1047 , 2008
Abstract : Kumar_2008_World.J.Microbiol.Biotechnol_24_1047
ESTHER : Kumar_2008_World.J.Microbiol.Biotechnol_24_1047
PubMedSearch : Kumar_2008_World.J.Microbiol.Biotechnol_24_1047
PubMedID:
Gene_locus related to this paper: pseae-rhla

Title : Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen - Stover_2000_Nature_406_959
Author(s) : Stover CK , Pham XQ , Erwin AL , Mizoguchi SD , Warrener P , Hickey MJ , Brinkman FS , Hufnagle WO , Kowalik DJ , Lagrou M , Garber RL , Goltry L , Tolentino E , Westbrock-Wadman S , Yuan Y , Brody LL , Coulter SN , Folger KR , Kas A , Larbig K , Lim R , Smith K , Spencer D , Wong GK , Wu Z , Paulsen IT , Reizer J , Saier MH , Hancock RE , Lory S , Olson MV
Ref : Nature , 406 :959 , 2000
Abstract : Stover_2000_Nature_406_959
ESTHER : Stover_2000_Nature_406_959
PubMedSearch : Stover_2000_Nature_406_959
PubMedID: 10984043
Gene_locus related to this paper: pseae-clipa , pseae-CPO , pseae-metx , pseae-PA0201 , pseae-PA0231 , pseae-PA0308 , pseae-PA0368 , pseae-PA0480 , pseae-PA0502 , pseae-PA0543 , pseae-PA0599 , pseae-PA0829 , pseae-PA1166 , pseae-PA1211 , pseae-PA1239 , pseae-PA1291 , pseae-PA1304 , pseae-PA1510 , pseae-PA1558 , pseae-PA1597 , pseae-PA1621 , pseae-PA1622 , pseae-PA1680 , pseae-PA1771 , pseae-PA1888 , pseae-PA1907 , pseae-PA1990 , pseae-PA2086 , pseae-PA2098 , pseae-PA2168 , pseae-PA2302 , pseae-PA2411 , pseae-PA2425 , pseae-PA2451 , pseae-PA2540 , pseae-PA2682 , pseae-PA2689 , pseae-PA2745 , pseae-PA2764 , pseae-PA2927 , pseae-PA2934 , pseae-PA2949 , pseae-PA3053 , pseae-PA3132 , pseae-PA3226 , pseae-PA3301 , pseae-PA3324 , pseae-PA3327 , pseae-PA3429 , pseae-PA3509 , pseae-PA3586 , pseae-PA3628 , pseae-PA3695 , pseae-PA3734 , pseae-PA3829 , pseae-PA3859 , pseae-PA3994 , pseae-PA4008 , pseae-PA4152 , pseae-PA4440 , pseae-PA4968 , pseae-PA5080 , pseae-PA5384 , pseae-PA5513 , pseae-PCHC , pseae-PCHF , pseae-PHAC1 , pseae-PHAC2 , pseae-phaD , pseae-phag , pseae-PVDD , pseae-q9i4b9 , pseae-q9i538 , pseae-rhla , pseae-Y2218 , pseae-q9hyv3 , pseae-q9i252 , pseae-q9i6m9

Title : Isolation, characterization, and expression in Escherichia coli of the Pseudomonas aeruginosa rhlAB genes encoding a rhamnosyltransferase involved in rhamnolipid biosurfactant synthesis - Ochsner_1994_J.Biol.Chem_269_19787
Author(s) : Ochsner UA , Fiechter A , Reiser J
Ref : Journal of Biological Chemistry , 269 :19787 , 1994
Abstract : Ochsner_1994_J.Biol.Chem_269_19787
ESTHER : Ochsner_1994_J.Biol.Chem_269_19787
PubMedSearch : Ochsner_1994_J.Biol.Chem_269_19787
PubMedID: 8051059
Gene_locus related to this paper: pseae-rhla