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Gene_locus Report for: rat-ab17c

Rattus norvegicus (Rat). Alpha/beta hydrolase domain-containing protein 17C

Relationship
Family|ABHD17-depalmitoylase
Block| X
Position in NCBI Life Tree|Rattus norvegicus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Myomorpha: N E > Muroidea: N E > Muridae: N E > Murinae: N E > Rattus: N E > Rattus norvegicus: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 2 more: AABR07004495, CH473980, BC107461
1 UniProt : B5DFK7
2 UniProt : B5DFK7, Q3B7U5
2 Interpro : B5DFK7, Q3B7U5
2 Pfam : B5DFK7, Q3B7U5
2 PIRSF : B5DFK7, Q3B7U5
2 SUPERFAM : B5DFK7, Q3B7U5
Sequence
Peptide
Graphical view for this peptide sequence: rat-ab17c
Colored MSA for ABHD17-depalmitoylase (raw) 
MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQR
APAPAATPAPAPAAQPAPAEEGAGPGACSLHLSERADWQYSQRELDAVEV
FFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRI
NCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYG
QSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSID
KISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIE
LYAQYLERLKQFISHELPNS
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA
MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQR
APAPAATPAPAPAAQPAPAEEGAGPGACSLHLSERADWQYSQRELDAVEV
FFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRI
NCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYG
QSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSID
KISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIE
LYAQYLERLKQFISHELPNS

References
    Title: Identification of PSD-95 Depalmitoylating Enzymes
    Yokoi N, Fukata Y, Sekiya A, Murakami T, Kobayashi K, Fukata M
    Ref: Journal of Neuroscience, 36:6431, 2016 : PubMed

            

    Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)
    Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R and Malek J <104 more author(s)>
    Ref: Genome Res, 14:2121, 2004 : PubMed

            

    Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution
    Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC and Collins F <218 more author(s)>
    Ref: Nature, 428:493, 2004 : PubMed

            


Other Papers

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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