Gene_locus Report for: rhiro-a0a2k6n885

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Primates: N E > Haplorrhini: N E > Simiiformes: N E > Catarrhini: N E > Cercopithecoidea: N E > Cercopithecidae: N E > Colobinae: N E > Rhinopithecus: N E > Rhinopithecus roxellana: N E

Title: Whole-genome sequencing of the snub-nosed monkey provides insights into folivory and evolutionary history
Zhou X, Wang B, Pan Q, Zhang J, Kumar S, Sun X, Liu Z, Pan H, Lin Y and Li R <24 more author(s)> Zhou X, Wang B, Pan Q, Zhang J, Kumar S, Sun X, Liu Z, Pan H, Lin Y, Liu G, Zhan W, Li M, Ren B, Ma X, Ruan H, Cheng C, Wang D, Shi F, Hui Y, Tao Y, Zhang C, Zhu P, Xiang Z, Jiang W, Chang J, Wang H, Cao Z, Jiang Z, Li B, Yang G, Roos C, Garber PA, Bruford MW, Li R (- 24)
Ref: Nat Genet, 46:1303, 2014 : PubMed
Abstract


ESTHER: Zhou_2014_Nat.Genet_46_1303
PubMedSearch: Zhou 2014 Nat.Genet 46 1303
PubMedID: 25362486
Gene_locus related to this paper: rhibe-a0a2k6jtl7, rhibe-ACHE, rhibe-a0a2k6k3y7, rhibe-a0a2k6k493, rhibe-a0a2k6lev4, rhibe-a0a2k6lfa5, rhibe-a0a2k6m6k8, rhiro-a0a2k6p1u8, rhiro-a0a2k6q1t8, rhiro-a0a2k6q1w3, rhibe-a0a2k6n5t9, rhibe-a0a2k6ju46, rhibe-a0a2k6kt48, rhibe-a0a2k6llm5, rhibe-a0a2k6lnt5, rhiro-a0a2k6qzp6, rhiro-a0a2k6q4a6, rhibe-a0a2k6kn93, rhibe-a0a2k6lm22, rhibe-a0a2k6jwp8, rhiro-a0a2k6qun2, rhiro-a0a2k6nj56, rhiro-a0a2k6n885, rhiro-a0a2k6nnj4, rhiro-a0a2k6n7n5, rhibe-a0a2k6jvz4, rhiro-a0a2k6nfk9, rhiro-a0a2k6qjv0, rhibe-a0a2k6jn19, rhibe-a0a2k6k333, rhibe-a0a2k6mff5

Abstract

Colobines are a unique group of Old World monkeys that principally eat leaves and seeds rather than fruits and insects. We report the sequencing at 146x coverage, de novo assembly and analyses of the genome of a male golden snub-nosed monkey (Rhinopithecus roxellana) and resequencing at 30x coverage of three related species (Rhinopithecus bieti, Rhinopithecus brelichi and Rhinopithecus strykeri). Comparative analyses showed that Asian colobines have an enhanced ability to derive energy from fatty acids and to degrade xenobiotics. We found evidence for functional evolution in the colobine RNASE1 gene, encoding a key secretory RNase that digests the high concentrations of bacterial RNA derived from symbiotic microflora. Demographic reconstructions indicated that the profile of ancient effective population sizes for R. roxellana more closely resembles that of giant panda rather than its congeners. These findings offer new insights into the dietary adaptations and evolutionary history of colobine primates.