Gene_Locus Report

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Gene_locus Report for: rhopd-ACHE1

Rhopalosiphum padi (Bird cherry-oat aphid) Aphis padi, Cotton aphid acetylcholinesterase

Relationship
Family|ACHE
Block| C
Position in NCBI Life Tree|Rhopalosiphum padi
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Panarthropoda: N E > Arthropoda: N E > Mandibulata: N E > Pancrustacea: N E > Hexapoda: N E > Insecta: N E > Dicondylia: N E > Pterygota: N E > Neoptera: N E > Paraneoptera: N E > Hemiptera: N E > Sternorrhyncha: N E > Aphidomorpha: N E > Aphidoidea: N E > Aphididae: N E > Aphidinae: N E > Aphidini: N E > Rhopalosiphum: N E > Rhopalosiphum padi complex: N E > Rhopalosiphum padi: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
1 mutation: rhopd-ACHE1
No structure
No kinetic





No Substrate
No inhibitor
2 Genbank : AY667435, KJ755963
2 UniProt : Q6BCH8, A0A076EE52
>3 UniProt links 69 more: Q6BCH8, A0A076EE52, A0A076E6F3
>3 Interpro links 69 more: Q6BCH8, A0A076EE52, A0A076E6F3
>3 Prodom links 69 more: Q6BCH8, A0A076EE52, A0A076E6F3
>3 Pfam links 69 more: Q6BCH8, A0A076EE52, A0A076E6F3
>3 PIRSF links 69 more: Q6BCH8, A0A076EE52, A0A076E6F3
>3 SUPERFAM links 69 more: Q6BCH8, A0A076EE52, A0A076E6F3
Sequence
Graphical view for this peptide sequence: rhopd-ACHE1
Colored MSA for ACHE (raw)
MDQWLLWFGYLVVSTYGLSLRHARHQSVGTPTAEEILEPQILIEDTDHVF
RQRASDMFAQEPEYTEKRNLNHRRRSEFSGNQDTDFASSGETYSAYTSDD
PLIIHTNKGKIRGITQTATTGKLVDAWLGIPYAKKPIGDLRFRHPRPIDR
WDTTSPETILNCTTPPNTCVQIFDTLFGDFPGATMWNPNSPVSEDCLYIN
VVVPKPRPQNAAVMVWIFGEGFYSGSATLDIYDPKILVSEENVILVSMQY
RVASLGFLYFDTEDVPGNAGLFDQLMALQWVHENIKLFGGNPNNVTLFGE
SAGAVSVSLHLLSPLSRNLFNQAIMESGSSTAPWAILSREESFSRGLKLA
KAMGCPDDRNAIHKTVECLRKANSSMMVEKEWDHVAICFFPFVPVVDGAF
LDDHPQKSLSTNNFKKTNILMGSNSEEGYYSIFYYLTELFKKEENVMVSR
ENFVKAIGQLNPNADAAVKSAIEFEYTDWFSPNDPEKNRNALDKMVGDYQ
FTCNVNEFAHKYALTGNNVYMYYFKHRSLNNPWPKWTGVMHGDEISYVFG
DPLNPNKRYEIEEIELSKKMMRYWTNFAKTGNPSKTLEGSWVTPKWPVHT
AYGKEFLTLDTNNTSIGVGPRLEQCAFWKNYVPDLTAISKSMKSDKNCTT
ISGGTKTNVIELSVWTIVMTTAVLML
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MDQWLLWFGYLVVSTYGLSLRHARHQSVGTPTAEEILEPQILIEDTDHVF
RQRASDMFAQEPEYTEKRNLNHRRRSEFSGNQDTDFASSGETYSAYTSDD
PLIIHTNKGKIRGITQTATTGKLVDAWLGIPYAKKPIGDLRFRHPRPIDR
WDTTSPETILNCTTPPNTCVQIFDTLFGDFPGATMWNPNSPVSEDCLYIN
VVVPKPRPQNAAVMVWIFGEGFYSGSATLDIYDPKILVSEENVILVSMQY
RVASLGFLYFDTEDVPGNAGLFDQLMALQWVHENIKLFGGNPNNVTLFGE
SAGAVSVSLHLLSPLSRNLFNQAIMESGSSTAPWAILSREESFSRGLKLA
KAMGCPDDRNAIHKTVECLRKANSSMMVEKEWDHVAICFFPFVPVVDGAF
LDDHPQKSLSTNNFKKTNILMGSNSEEGYYSIFYYLTELFKKEENVMVSR
ENFVKAIGQLNPNADAAVKSAIEFEYTDWFSPNDPEKNRNALDKMVGDYQ
FTCNVNEFAHKYALTGNNVYMYYFKHRSLNNPWPKWTGVMHGDEISYVFG
DPLNPNKRYEIEEIELSKKMMRYWTNFAKTGNPSKTLEGSWVTPKWPVHT
AYGKEFLTLDTNNTSIGVGPRLEQCAFWKNYVPDLTAISKSMKSDKNCTT
ISGGTKTNVIELSVWTIVMTTAVLML


References
    Title: Mutations in acetylcholinesterase genes of Rhopalosiphum padi resistant to organophosphate and carbamate insecticides
    Chen MH, Han ZJ, Qiao XF, Qu MJ
    Ref: Genome, 50:172, 2007 : PubMed

            

    Title: Cloning and sequence analysis of 2 different acetylcholinesterase genes in Rhopalosiphum padi and Sitobion avenae
    Chen M, Han Z
    Ref: Genome, 49:239, 2006 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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