Gene_locus Report for: sacd2-q21ms2 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Putative uncharacterized protein
Relationship
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.) cellular organisms: N E > Bacteria: N E > Proteobacteria: N E > Gammaproteobacteria: N E > Cellvibrionales: N E > Cellvibrionaceae: N E > Saccharophagus: N E > Saccharophagus degradans: N E 6_AlphaBeta_hydrolase :
sacd2-q21eu2 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein precursor ,
sacd2-q21fh8 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hydrolase, alpha/beta fold family ,
sacd2-q21ix4 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) putative hydrolase precursor .
A85-Est-Putative :
sacd2-q21gn2 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) atpase .
A85-EsteraseD-FGH :
sacd2-q21pr4 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) periplasmic nitrate reductase, large subunit (EC 3.1.1.1) .
A85-Feruloyl-Esterase :
sacd2-q21dw3 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) enterochelin esterase and related enzymes-like precursor ,
sacd2-q21fx0 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Putative esterase .
A85-IroE-IroD-Fes-Yiel :
sacd2-q21gd4 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hydrolase of the alpha/beta superfamily-like precursor ,
sacd2-q21gq4 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) cysteine synthase a precursor .
ABHD11-Acetyl_transferase :
sacd2-q21fh6 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein .
abh_upf0017 :
sacd2-q21l72 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Hydrolase of the alpha/beta-hydrolase fold .
abh_upf00227 :
sacd2-q21nu2 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) dna repair protein rada .
ACPH_Peptidase_S9 :
sacd2-q21ib9 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like precursor .
AHL-acylase :
sacd2-q21ez0 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Hydrolases or acyltransferases (Alpha/beta hydrolase superfamily)-like .
BD-FAE :
sacd2-q21fw5 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) esterase/lipase-like precursor ,
sacd2-q21gs2 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) putative lipase/esterase precursor .
BioH :
sacd2-q21fy5 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Biotin biosynthesis protein BioC .
Dienelactone_hydrolase :
sacd2-q21kh3 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) threonyl-trna synthetase, class IIa .
Duf_900 :
sacd2-q21i07 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein .
Homoserine_transacetylase :
sacd2-q21ei0 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) dna/pantothenate metabolism flavoprotein (EC 2.3.1.31) .
Hydrolase_RBBP9_YdeN :
sacd2-q21f58 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein .
Lipase_3 :
sacd2-q21dy1 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein ,
sacd2-q21lv2 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) galactose-1-phosphate uridyl transferase, class i .
LYsophospholipase_carboxylesterase :
sacd2-q21kk3 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) carboxylesterase (EC 3.1.1.1) .
Monoglyceridelipase_lysophospholip :
sacd2-q21f03 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Putative uncharacterized protein .
NLS3-Tex30 :
sacd2-q21ll5 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Uncharacterized protein .
PHA_synth_I :
sacd2-q21l41 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) polyhydroxyalkanoic acid synthase .
PHB_depolymerase_PhaZ :
sacd2-q21jj4 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein .
PMH_Peptidase_S9 :
sacd2-q21ld1 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein .
Proline_iminopeptidase :
sacd2-q21nb3 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) prolyl aminopeptidase (EC 3.4.11.5) .
Prolyl_oligopeptidase_S9 :
sacd2-q21pq4 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) prolyl oligopeptidase family protein precursor .
Thioesterase :
sacd2-q21e96 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) oleoyl-(acyl-carrier protein) hydrolase (EC 3.1.2.14) ,
sacd2-q21e99 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) polyketide synthase modules and related proteins-like ,
sacd2-q21hw8 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) thioesterase involved in non-ribosomal peptide biosynthesis-like .
Tiancimycin-TnmK-Tripeptidase-HIP :
sacd2-q21n23 Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) hypothetical protein precursor Molecular evidence
Database
No mutation No structure No kinetic No Substrate No inhibitor
Sequence
Graphical view for this peptide sequence: sacd2-q21ms2 Colored MSA for Duf_3530 (raw)
MKIRLNHFFSRALIITLCFSATSHLALAQEEDTAQQEQTKPKPPPPRAVP
DTNKQAERLLSEELGEDAIVWLNAAGEKFISLWEPDRSGNPFGAILIVHG
EGQTADWPYTIRALRQSLPDHGWSTLSISLPNPAETPPPARPSGDTTPPS
KPTPPPTEPIVIERMKAAMSYLNKRGQYNIVILAHGVGASRSVQYLSQLS
TSRPNNLPSGGRSRATAIIDRPIRALIMVNARNGIEGADDNLTEYLTDRS
LPVMDIFFGDHVLDATEPDQRKMAAKKNRIAHYHQSKLLEPSANWQEGEN
RLTRRVRGFLNKYAKGVEIDG
Legend
This sequence has been compared to family alignement (MSA) red => minority aminoacid blue => majority aminoacid color intensity => conservation rate title => sequence position(MSA position)aminoacid rate Catalytic site Catalytic site in the MSA
M K I R L N H F F S R A L I I T L C F S A T S H L A L A Q E E D T A Q Q E Q T K P K P P P P R A V P D T N K Q A E R L L S E E L G E D A I V W L N A A G E K F I S L W E P D R S G N P F G A I L I V H G E G Q T A D W P Y T I R A L R Q S L P D H G W S T L S I S L P N P A E T P P P A R P S G D T T P P S K P T P P P T E P I V I E R M K A A M S Y L N K R G Q Y N I V I L A H G V G A S R S V Q Y L S Q L S T S R P N N L P S G G R S R A T A I I D R P I R A L I M V N A R N G I E G A D D N L T E Y L T D R S L P V M D I F F G D H V L D A T E P D Q R K M A A K K N R I A H Y H Q S K L L E P S A N W Q E G E N R L T R R V R G F L N K Y A K G V E I D G
Reference
Title: Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 TWeiner RM , Taylor LE, 2nd , Henrissat B , Hauser L , Land M , Coutinho PM , Rancurel C , Saunders EH , Longmire AG and Hutcheson S <9 more author(s)> Weiner RM , Taylor LE, 2nd , Henrissat B , Hauser L , Land M , Coutinho PM , Rancurel C , Saunders EH , Longmire AG , Zhang H , Bayer EA , Gilbert HJ , Larimer F , Zhulin IB , Ekborg NA , Lamed R , Richardson PM , Borovok I , Hutcheson S (- 9) Ref: PLoS Genet, 4 :e1000087, 2008 : PubMed Abstract ESTHER: Weiner_2008_PLoS.Genet_4_E1000087 PubMedSearch: Weiner 2008 PLoS.Genet 4 E1000087 PubMedID: 18516288 Gene_locus related to this paper: sacd2-q21f03 ,
sacd2-q21l72 ,
sacd2-q21ms2 ,
sacd2-q21ll5 Abstract
The marine bacterium Saccharophagus degradans strain 2-40 (Sde 2-40) is emerging as a vanguard of a recently discovered group of marine and estuarine bacteria that recycles complex polysaccharides. We report its complete genome sequence, analysis of which identifies an unusually large number of enzymes that degrade >10 complex polysaccharides. Not only is this an extraordinary range of catabolic capability, many of the enzymes exhibit unusual architecture including novel combinations of catalytic and substrate-binding modules. We hypothesize that many of these features are adaptations that facilitate depolymerization of complex polysaccharides in the marine environment. This is the first sequenced genome of a marine bacterium that can degrade plant cell walls, an important component of the carbon cycle that is not well-characterized in the marine environment.
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