Gene_Locus Report

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Gene_locus Report for: strhy-FKBU

Streptomyces hygroscopicus subsp. ascomyceticus polyhydroxybutyrate depolymerase

Comment
only n-term Pfam A Esterase_phd 57 276


Relationship
Family|Esterase_phb
Block| X
Position in NCBI Life Tree|Streptomyces hygroscopicus subsp. ascomyceticus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Streptomycetales: N E > Streptomycetaceae: N E > Streptomyces: N E > Streptomyces hygroscopicus: N E > Streptomyces hygroscopicus subsp. ascomyceticus: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : AF235504
1 UniProt : Q9KIF2
1 Interpro : Q9KIF2
1 Prodom : Q9KIF2
1 Pfam : Q9KIF2
1 PIRSF : Q9KIF2
1 SUPERFAM : Q9KIF2
Sequence
Graphical view for this peptide sequence: strhy-FKBU
Colored MSA for Esterase_phb (raw)
MQPPPFRGILTPLFPLSSSPPVGSLSRPGRRGVLTRLVAVVALVLGAALL
GPAPTAHAAAGLAKPGLTKADLTEVADFGTNPGRLNMYVYRPASLPAEPA
VVFALHGCTQDAQGYADNSGLLSFADRYGFLLVFAETTSSNNANRCFNWF
QSSDNRRGQGEAASIRQMAAHTVSAYGADPQRTYITGLSAGGAMTSVMLA
TYPDVFQAGAVVAGLPFGCATDVSSAYLCMNPGTDLTADQWARRVRDGYP
SWSGPWPRVAIWHGDKDTTVAPRNADELRDQWTAVHGVSQTPDRTSVIGP
NSTRHEEYLAADGSVAVEVNRVPGIGHGTPVDPGTGAQQCGSTGAAYFLD
SICSSYWITQFFGLSGSASD
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MQPPPFRGILTPLFPLSSSPPVGSLSRPGRRGVLTRLVAVVALVLGAALL
GPAPTAHAAAGLAKPGLTKADLTEVADFGTNPGRLNMYVYRPASLPAEPA
VVFALHGCTQDAQGYADNSGLLSFADRYGFLLVFAETTSSNNANRCFNWF
QSSDNRRGQGEAASIRQMAAHTVSAYGADPQRTYITGLSAGGAMTSVMLA
TYPDVFQAGAVVAGLPFGCATDVSSAYLCMNPGTDLTADQWARRVRDGYP
SWSGPWPRVAIWHGDKDTTVAPRNADELRDQWTAVHGVSQTPDRTSVIGP
NSTRHEEYLAADGSVAVEVNRVPGIGHGTPVDPGTGAQQCGSTGAAYFLD
SICSSYWITQFFGLSGSASD


Reference
    Title: The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units
    Wu K, Chung L, Revill WP, Katz L, Reeves CD
    Ref: Gene, 251:81, 2000 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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