strpy-PEPXP

Streptococcus pyogenes, putative x-pro dipeptidyl-peptidase IV (EC 3.4.14.11)

Comment

Other strains: Streptococcus pyogenes (strain ATCC 10782) and (serotype M3) (serotype M18\; strain SSI-1) s (serotype M6, serotype M28 (strain MGAS6180), serotype M1) serotype M12 (strains MGAS2096\; MGAS9429) serotype M2 (strain MGAS10270)serotype M4 (strain MGAS10750) serotype M5 (strain Manfredo) serotype M49 (strain NZ131)\; serotype M3 (strain ATCC BAA-595 \/ MGAS315) || Very close to Lactobacillus peptidases (horizontal transfer?)

Relationship

Family : Lactobacillus_peptidase

Block : X

Position in NCBI Life Tree : Streptococcus pyogenes

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

MRYNQFSYIP TSLERAAEEL KELGFDLDLQ KTAKASLESF LRKLFFHYPD SDYPLSHLIA KNDMDALSFF QSEQELSKEV FDLLALQVLG FIPGVDFTEA DAFLDKLAFP IHFDETEIIK HIHHLLATRC KSGMTLIDDL VSQGMLTMDN DYHFFNGKSL ATFDTSQLIR EVVYVEAPLD TDQDGQLDLI KVNIIRPQSQ KPLPTLMTPS PYHQGINEVA NDKKLYRMEK ELVVKKRRQI TVEDRDFIPL ETQPCKLPIG QNLESFSYIN SYSLNDYFLA RGFANIYVSG VGTAGSTGFM TSGNYAQIES FKAVIDWLNG RATAYTSHSK THQVRADWAN GLVCTTGKSY LGTMSTGLAT TGVDGLAMII AESAISSWYN YYRENGLVCS PGGYPGEDLD VLTELTYSRN LLAGDYLRHN DRYQELLNQQ SQALDRQSGD YNQFWHDRNY LKNAHQIKCD VVYTHGLQDW NVKPRQVYEI FNALPSTINK HLFLHQGEHV YMHNWQSIDF RESMNALLCQ KLLGLANDFS LPEMIWQDNT CPQNWQERKV FGTSTIKELD LGQELLLIDN HYGEDEFKAY GKDFRAFKAA LFKGKANQAL IDILLEEDLP INGEIVLQLK VKSSENKGLL SAQILDYGKK KRLGDLPIAL TQSSIDNGQN FSREPLKELP FREDSYRVIS KGFMNLQNRN NLSSIETIPN NKWMTVRLPL QPTIYHLEKG DTLRVILYTT DFEHTVRDNS NYALTIDLSQ SQLIVPIASN

References

Title : Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes - McShan_2008_J.Bacteriol_190_7773
Author(s) : McShan WM , Ferretti JJ , Karasawa T , Suvorov AN , Lin S , Qin B , Jia H , Kenton S , Najar F , Wu H , Scott J , Roe BA , Savic DJ
Ref : Journal of Bacteriology , 190 :7773 , 2008
Abstract : McShan_2008_J.Bacteriol_190_7773
ESTHER : McShan_2008_J.Bacteriol_190_7773
PubMedSearch : McShan_2008_J.Bacteriol_190_7773
PubMedID: 18820018
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-SPY1308

Title : Complete genome of acute rheumatic fever-associated serotype M5 Streptococcus pyogenes strain manfredo - Holden_2007_J.Bacteriol_189_1473
Author(s) : Holden MT , Scott A , Cherevach I , Chillingworth T , Churcher C , Cronin A , Dowd L , Feltwell T , Hamlin N , Holroyd S , Jagels K , Moule S , Mungall K , Quail MA , Price C , Rabbinowitsch E , Sharp S , Skelton J , Whitehead S , Barrell BG , Kehoe M , Parkhill J
Ref : Journal of Bacteriology , 189 :1473 , 2007
Abstract : Holden_2007_J.Bacteriol_189_1473
ESTHER : Holden_2007_J.Bacteriol_189_1473
PubMedSearch : Holden_2007_J.Bacteriol_189_1473
PubMedID: 17012393
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-SPY1308 , strpy-SPYM18.1727

Title : Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus - Beres_2006_Proc.Natl.Acad.Sci.U.S.A_103_7059
Author(s) : Beres SB , Richter EW , Nagiec MJ , Sumby P , Porcella SF , Deleo FR , Musser JM
Ref : Proc Natl Acad Sci U S A , 103 :7059 , 2006
Abstract : Beres_2006_Proc.Natl.Acad.Sci.U.S.A_103_7059
ESTHER : Beres_2006_Proc.Natl.Acad.Sci.U.S.A_103_7059
PubMedSearch : Beres_2006_Proc.Natl.Acad.Sci.U.S.A_103_7059
PubMedID: 16636287
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-SPY1308 , strpy-SPYM18.1727

Title : Genome sequence of a serotype M28 strain of group a streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity - Green_2005_J.Infect.Dis_192_760
Author(s) : Green NM , Zhang S , Porcella SF , Nagiec MJ , Barbian KD , Beres SB , LeFebvre RB , Musser JM
Ref : J Infect Dis , 192 :760 , 2005
Abstract : Green_2005_J.Infect.Dis_192_760
ESTHER : Green_2005_J.Infect.Dis_192_760
PubMedSearch : Green_2005_J.Infect.Dis_192_760
PubMedID: 16088825
Gene_locus related to this paper: strpm-q48rv0 , strpy-ESTA , strpy-PEPXP , strpy-SPY1308

Title : Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events - Sumby_2005_J.Infect.Dis_192_771
Author(s) : Sumby P , Porcella SF , Madrigal AG , Barbian KD , Virtaneva K , Ricklefs SM , Sturdevant DE , Graham MR , Vuopio-Varkila J , Hoe NP , Musser JM
Ref : J Infect Dis , 192 :771 , 2005
Abstract : Sumby_2005_J.Infect.Dis_192_771
ESTHER : Sumby_2005_J.Infect.Dis_192_771
PubMedSearch : Sumby_2005_J.Infect.Dis_192_771
PubMedID: 16088826
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-SPY1308 , strpy-SPYM18.1727

Title : Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain - Banks_2004_J.Infect.Dis_190_727
Author(s) : Banks DJ , Porcella SF , Barbian KD , Beres SB , Philips LE , Voyich JM , Deleo FR , Martin JM , Somerville GA , Musser JM
Ref : J Infect Dis , 190 :727 , 2004
Abstract : Banks_2004_J.Infect.Dis_190_727
ESTHER : Banks_2004_J.Infect.Dis_190_727
PubMedSearch : Banks_2004_J.Infect.Dis_190_727
PubMedID: 15272401
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-SPY1308 , strpy-SPYM18.1727

Title : Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution - Nakagawa_2003_Genome.Res_13_1042
Author(s) : Nakagawa I , Kurokawa K , Yamashita A , Nakata M , Tomiyasu Y , Okahashi N , Kawabata S , Yamazaki K , Shiba T , Yasunaga T , Hayashi H , Hattori M , Hamada S
Ref : Genome Res , 13 :1042 , 2003
Abstract : Nakagawa_2003_Genome.Res_13_1042
ESTHER : Nakagawa_2003_Genome.Res_13_1042
PubMedSearch : Nakagawa_2003_Genome.Res_13_1042
PubMedID: 12799345
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-SPY1308

Title : Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks - Smoot_2002_Proc.Natl.Acad.Sci.U.S.A_99_4668
Author(s) : Smoot JC , Barbian KD , Van Gompel JJ , Smoot LM , Chaussee MS , Sylva GL , Sturdevant DE , Ricklefs SM , Porcella SF , Parkins LD , Beres SB , Campbell DS , Smith TM , Zhang Q , Kapur V , Daly JA , Veasy LG , Musser JM
Ref : Proc Natl Acad Sci U S A , 99 :4668 , 2002
Abstract : Smoot_2002_Proc.Natl.Acad.Sci.U.S.A_99_4668
ESTHER : Smoot_2002_Proc.Natl.Acad.Sci.U.S.A_99_4668
PubMedSearch : Smoot_2002_Proc.Natl.Acad.Sci.U.S.A_99_4668
PubMedID: 11917108
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-SPY1308 , strpy-SPYM18.1727 , strpy-SPYM18.1957

Title : Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence - Beres_2002_Proc.Natl.Acad.Sci.U.S.A_99_10078
Author(s) : Beres SB , Sylva GL , Barbian KD , Lei B , Hoff JS , Mammarella ND , Liu MY , Smoot JC , Porcella SF , Parkins LD , Campbell DS , Smith TM , McCormick JK , Leung DY , Schlievert PM , Musser JM
Ref : Proceedings of the National Academy of Sciences of the United States of America , 99 :10078 , 2002
Abstract : Beres_2002_Proc.Natl.Acad.Sci.U.S.A_99_10078
ESTHER : Beres_2002_Proc.Natl.Acad.Sci.U.S.A_99_10078
PubMedSearch : Beres_2002_Proc.Natl.Acad.Sci.U.S.A_99_10078
PubMedID: 12122206
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-Q8K5W4 , strpy-SPY1308 , strpy-SPYM18.1727

Title : Complete genome sequence of an M1 strain of Streptococcus pyogenes - Ferretti_2001_Proc.Natl.Acad.Sci.U.S.A_98_4658
Author(s) : Ferretti JJ , McShan WM , Ajdic D , Savic DJ , Savic G , Lyon K , Primeaux C , Sezate S , Suvorov AN , Kenton S , Lai HS , Lin SP , Qian Y , Jia HG , Najar FZ , Ren Q , Zhu H , Song L , White J , Yuan X , Clifton SW , Roe BA , McLaughlin R
Ref : Proc Natl Acad Sci U S A , 98 :4658 , 2001
Abstract : Ferretti_2001_Proc.Natl.Acad.Sci.U.S.A_98_4658
ESTHER : Ferretti_2001_Proc.Natl.Acad.Sci.U.S.A_98_4658
PubMedSearch : Ferretti_2001_Proc.Natl.Acad.Sci.U.S.A_98_4658
PubMedID: 11296296
Gene_locus related to this paper: strpy-ESTA , strpy-PEPXP , strpy-Q8K5W4 , strpy-SPY1308 , strpy-SPYM18.1727