Gene_Locus Report

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Gene_locus Report for: trisp-e5s3s1

Trichinella spiralis (Trichina worm); T. nelsoni; T. murrelli; T. sp.; T. patagoniensis; T. britovi; T. zimbabwensis; T pseudospiralis; T nativa; T. papuae, Acetylcholinesterase

Comment
Other strains: Trichinella spiralis (Trichina worm); Trichinella nelsoni; Trichinella murrelli; Trichinella sp. (T6;T8); Trichinella patagoniensis; Trichinella britovi; Trichinella zimbabwensis; Trichinella pseudospiralis; Trichinella nativa; Trichinella papuae only c-term is cholinesterase closer to vert cholinesterase !?


Relationship
Family|ACHE
Block| C
Position in NCBI Life Tree|Trichinella spiralis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Protostomia: N E > Ecdysozoa: N E > Nematoda: N E > Enoplea: N E > Dorylaimia: N E > Trichinellida: N E > Trichinellidae: N E > Trichinella: N E > Trichinella spiralis: N E
Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
>3 Genbank links 9 more: ABIR02000368, JYDL01000060, JYDJ01000088
>3 UniProt links 8 more: A0A0V0RYL7, A0A0V0U0P3, A0A0V0X2Z4
>3 UniProt links 26 more: A0A0V0RYL7, A0A0V0U0P3, A0A0V0U0P7
>3 Interpro links 26 more: A0A0V0RYL7, A0A0V0U0P3, A0A0V0U0P7
>3 Pfam links 26 more: A0A0V0RYL7, A0A0V0U0P3, A0A0V0U0P7
>3 PIRSF links 26 more: A0A0V0RYL7, A0A0V0U0P3, A0A0V0U0P7
>3 SUPERFAM links 26 more: A0A0V0RYL7, A0A0V0U0P3, A0A0V0U0P7
Sequence
Graphical view for this peptide sequence: trisp-e5s3s1
Colored MSA for ACHE (raw)
LSLSMISLAVVILVVNLFFTFIQTSKAHTALVNTTSGWLQGTVLQMENAT
TTTATVYEFLNISYGHAPVGNYRFAKPLPASYQFGIIYSNTSAPPCYQYV
DQSYPGFAGTEMWNPSFEMTENCLNLNLWQPANAKNAPVLVWIFGGGFVS
GSPSLDLYNGSTIAARHGIIVININYRLGPLGFLYLDDKEAPPNVGLLDQ
RLALQWIQENVQLFGGDPSRITLMGESAGAAAVMSHLLAKNSWHLFNNAI
LQSGTMNSSWATVDREILKNHSRELASSLGCSGSDLELLRCLRKLPAQDI
QSKSEKMWNGKFLSFLFAPVINDELFFGEESSRNLITGNMKKTTILVCFN
SDEGSFWLPTYMPKFFNNIGDGMISRTQFYSAVEEAFGDFQNHHQLEQVM
EYYLANYANERDALSAMIGDFYFTCDLLYTVHLVTDKGVRVYLSQFDYRS
ERNPWPQWMGSMHGYEIEFIFGVPLRPENGNYSPHDQFISKLLMEYWSSF
VYDSQPTANSTAHVKWPLYTAENPAYLMINESGVSVQWNPLKYECSLMRQ
LKLGKLNII
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

LSLSMISLAVVILVVNLFFTFIQTSKAHTALVNTTSGWLQGTVLQMENAT
TTTATVYEFLNISYGHAPVGNYRFAKPLPASYQFGIIYSNTSAPPCYQYV
DQSYPGFAGTEMWNPSFEMTENCLNLNLWQPANAKNAPVLVWIFGGGFVS
GSPSLDLYNGSTIAARHGIIVININYRLGPLGFLYLDDKEAPPNVGLLDQ
RLALQWIQENVQLFGGDPSRITLMGESAGAAAVMSHLLAKNSWHLFNNAI
LQSGTMNSSWATVDREILKNHSRELASSLGCSGSDLELLRCLRKLPAQDI
QSKSEKMWNGKFLSFLFAPVINDELFFGEESSRNLITGNMKKTTILVCFN
SDEGSFWLPTYMPKFFNNIGDGMISRTQFYSAVEEAFGDFQNHHQLEQVM
EYYLANYANERDALSAMIGDFYFTCDLLYTVHLVTDKGVRVYLSQFDYRS
ERNPWPQWMGSMHGYEIEFIFGVPLRPENGNYSPHDQFISKLLMEYWSSF
VYDSQPTANSTAHVKWPLYTAENPAYLMINESGVSVQWNPLKYECSLMRQ
LKLGKLNII


Reference
    Title: The draft genome of the parasitic nematode Trichinella spiralis
    Mitreva M, Jasmer DP, Zarlenga DS, Wang Z, Abubucker S, Martin J, Taylor CM, Yin Y, Fulton L and Wilson RK <11 more author(s)>
    Ref: Nat Genet, 43:228, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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