ESTHER Database

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MSA from Cobalt (Ncbi) Cobalt
Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....
9brad-q35ez6   	-----------------------------------------------------------------MPEVIFNGPAGRLEGRYHPAK------QKNAPIAMILHPHPQFHGTMNHQIVYQCYYAFAHRGFSVLRFNFRGVGRSQGSFDHGTGELSDAASALDWAQTI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPPAN------LYDFSF-LAPCPSSGLIVHGEKDAVVPPKDVNTLVEKLKT-QKGIVIDQQIIPGANHFFDG---KLEPLMETITAYLDMRLANVR--------------------     =====>
9gamm-q1n071   	-----------------------------------------------------------------MESLMIEGPVGQLEAAYHDV--------GSDDVLLICHPHPLYQGTMNNKVVTYTGKTYMDLGVNVMRFNYRGVGKSEGEYGEVSGEVQDGVAVARWLIEH------KQPKR-LFLAGFSFGAYIAAAIVQELQSG--------VTIPHLLLIAPSVDN------FPFDT-VTPFTVPSSVIMGEQDEVVSFASVEEWVEGLYP-----PVQFITLREATHFFHG---QLVTLRDELKELLDPIL------------------------     =====>
9rhiz-q0g705   	-----------------------------------------------------------------MPEVIFTGPAGRLEGRYQPAK------EKNAPIAIVLHPHPRFGGTMNNQIVYQLFYMFVERGFTTLRFNFRGIGRSQGEFDHGSGELSDAASALDWIQSI------HPDSKETWVAGYSFGAWIGMQLLMR-----------RPEIEGFFSIAPQPN------TYDFSF-LAPCPSSGLIIHGDRDRVAPPKDVQVLVDKLKS-QKGIVITHKTMEGANHFFQD---QTDSLIANCSEYLDQRLAGELSD-PKLKRLR----------     =====>
9rhiz-q1ynl4   	-----------------------MNHSKLDPTRPLR------------LRQVRPAEPSRSPRNIIMPEVIFNGPAGRLEGRYQAAK------EKNAPIAIVLHPHPRFGGTMNNQIVYKLFYMFVERGFTTLRFNFRGIGRSQGEFDHGSGELSDAASALDWVQSL------HPDSKQCWVAGYSFGAWIGMQLLMR-----------RPEIEGFFSISPQPN------SYDFSF-LAPCPSSGLIIHGDKDRVAPPKDVQTLVDKLKT-QKGIVITQKTMEGANHFYSE---HTDELLGECSEYLDRRLAGELSD-PRPKRLR----------     =====>
9rhob-a0nqk0   	-----------------------------------------------------------------MPEVIFNGPAGRLEGRFHPAR------KRNAPIALVLHLHPQFGGTMNNQIVYQMYYMFARRGFAVLRFNFRGVGRSQGSFDHGQGELSDAAAALDWVQTV------HTDARACWIAGFSFGAWIGMQLLMR-----------RPEVEGFISVAPPAN------LHDFSF-LAPCPSSGLIIHGDNDKVVPQKDVQTLVDKLKT-QKGIVIDHETIPGANHFFEN---DMDELMQRCGTYVDGRLGLSPSDYVDID-------------     =====>
9rhob-q0fgl2   	-----------------------------------------------------------------MPEVIFPGPDGRLEGRYHPQK------TKDAPIAILLHPHPQFGGTMNNKVVYNLHYAFYNMGFTVLRFNFRGVGRSQGEYDQGVGELSDAASALDYLQAM------NPNAKHCWVAGFSFGAWIGMQLLMR-----------RPEISGFISAAPPAN------TYDFSF-LAPCPASGLIINGSSDRVVPPVDVEGLVGKLHE-QKGITITHEVLEGSGHFFEN--DHMDTMIGSVDTYVRRRLTENTR-------------------     =====>
9rhob-q2cg70   	-----------------------------------------------------------------MPEVIFPGPEGRLEGRYHPQR------DRDAPIAIVLHPHPQFGGTMNNRVVYNLHYAFYKLGFTVLRFNFRGVGRSQGEYDQGVGELSDAASALDYLQSM------NANAKHCWVAGFSFGAWIGMQLLMR-----------RPEITGFVSVSPPAN------MYDFSF-LAPCPSSGLVINGSGDRVAPPQDTVNLVNKLHE-QKGITITHQTVEGAGHFFED--PHMDTMITSVSEYVGRRLTETTR-------------------     =====>
9sphn-q1nal4   	-----------------------------------------------------------------MPDVIFPGPEGRLEGRFSPPP------RPRAPVAMILHPHPQGGGTMNDRITQALYKTFVKRGFAVLRFNFRGVGRSQGTFDNGVGELSDAAAALDWVQSF------HPEAQTTWIAGFSFGAWIGMQLLMR-----------RPEIRGFISVAPPAN------MYDFSF-LAPCPSSGIIVQGTSDEVVTASAVQKLVDKLRT-QKGITIHHDEIRGANHFFEH---ELDQLMKSVDNYLDMRLSPDSPIR-----------------     =====>
9sphn-q2ncr2   	-----------------------------------------------------------------MPTVIFPGPEGRLEGRFSPPP------RPRAPVAMILHPHPQGGGTMNEQITQKLYKTFVDRGFATLRFNFRGVGRSQGSFDNGIGELSDAAAALDWVQSI------HEEAQVTWVAGVSFGALIGMQLLMR-----------RPEIRGWISIGAPAS------MYDFSF-LAPCPASGIFIHGAQDTVVQPSSVTKLVEKLRT-QKHITVHHEEIPRANHFFQN---EQDELMASVDNYLDFRLDPACPIT-----------------     =====>
9sphn-q3vck8   	-----------------------------------------------------------------MPDVIFPGPEGRIEGRFSPPP------RPRAPVALILHPHPQGGGTMNDRITQAMYKSFVARGFAVLRFNFRGVGRSQGTFDNGIGELSDAASALDWVQSI------HPEAQTTWVAGFSFGAWIGMQLLMR-----------RPEIRGFLSVAPPAN------MYDFSF-LAPCPSSGIIVAGGQDEIVPPSAVQKLVDKLRT-QKGITIHHDEIPRANHFFEH---ELDQLMKSLDNYLDMRLAPDSPIR-----------------     =====>
acicy-q2dcd9   	-----------------------------------------------------------------MPEVMFAGPDGRLEGRYHHAK------DRGAPLALVLHPHPLHGGTMNNRITYTMYQVFQRLGFSVMRFNFRGVGRSQGSYDGGMGEINDAAAALDWMQAL------NPGHGGLWISGYSFGAFVGMQLLMR-----------RPEVSGWISVAPPAA------HYDFGF-LAPCPCGGLMIHGDADELVPEISVRKLVDKLNT-QKGVAVDYRVLEGADHVFAN---HADAIGQAVEAYVSGEIARKHMALAAD--------------     =====>
agrtu-ATU1826  	-----------------------------------------------------------------MPEVIFNGPAGRLEGRYQPSK------EKSAPIAIILHPHPQFGGTMNNQIVYQLFYLFQKRGFTTLRFNFRSIGRSQGEFDHGAGELSDAASALDWVQSL------HPDSKSCWVAGYSFGAWIGMQLLMR-----------RPEIEGFMSIAPQPN------TYDFSF-LAPCPSSGLIINGDADKVAPEKDVNGLVEKLKT-QKGILITHRTLPGANHFFNG---KVDELMGECEDYLDRRLNGELVPEPAAKRIR----------     =====>
azovi-q4iye1   	-------------------------------------------------------------MSNRENSLFIDGPCGPLEALYLEI-------PQARGLALLCHPNPVKGGTMLNKVVSTLQRTARDAGYSTLRFNYRGVGASAGDHDMGSGEVDDAEAVVRWVRGQ------LPQLP-LNIFGFSFGGYVALNLAERLAVL-------GQVPERMFLVAPAVMR------LDRATMIVPQGSDLTIIQPEQDEVVSPQLVYDWSAALQR-----PHELLKVAECGHFFHG---RLGELKDLVSSRL----------------------------     =====>
barbk-a1usz5   	-----------------------------------------------------------------MPEIIFNGPVGRLEGRYQPSQ------QKNAPIAIVLHPHPQFGGTMNNRIVYDLFYMFHQRGFTTLRFNFRGIGRSQGEFDYGTGELSDAAAALDWVQTQ------HPDSQNCWVAGYSFGAWIGMQLLMR-----------RPEIESFISVAPQPN------IYDFSF-LAPCPSSGLIIHGDADKVSPPKDVQTLVDKLKM-QKGITIMQEILEGANHFFSG---YNEKLLERCAQYLDNHIANERLVSPLAISSSYSERKKAYKK     =====>
barqu-q6fzw3   	-----------------------------------------------------------------MPEIIFNGPAGRLEGRYQPSQ------QKNAPIAIILHPHPQFGGTMNNKIVYDLFYMFQQRGFTTLRFNFRGIGRSQGEFDYGIGELSDAAAALDWVQTQ------HPDSKNCWVAGYSFGAWIGMQLLMR-----------RPEIESFISVAPQPN------IYDFSF-LAPCPSSGLIIHGDIDKVAPPKDVQTLVDKLKT-QKGIIITQEILEGANHFFSG---CTQELIERCAQYLDNHMTNEFLIPSSEILSLT---------     =====>
braja-BLL4335  	-----------------------------------------------------------------MPEVIFAGPAGRLEGRYHPAK------QKNAPIAMILHPHPQFHGTMNHQIVYQCYYAFAHRGFSVLRFNFRGVGRSQGSFDHGTGELSDAAAALDWAQTI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPPAN------LYDFSF-LAPCPSSGLIVHGEKDAVVPPKDVNTLVEKLKT-QKGIVIDQQVIPGANHFFDA---KLEPLMETITAYLDMRLANVR--------------------     =====>
brume-BMEI1044 	-----------------------------------------------------------------MPEVIFNGPAGRLEGRYQPSK------EKNAPIALILHPHPQFGGTMNNKIVYDLFYMFQQRGFTTLRFNFRGIGRSQGEFDHGAGELSDAASALDWVQAL------HPDSKTCWVAGYSFGAWIGMQLLMR-----------RPEIEGFISVAPQPN------TYDFSF-LAPCPSSGLIIHGDQDKVAPPKDVQALVDKLKT-QKGITITQKTIASANHFFTG---QGEELIEECSEYLDRRLAGELVE-ARPKRLR----------     =====>
burxl-q146f8   	-------------------------------------------------------------MNAYTKKYLIDGPVGKIEVAVDLPDETRESGAAPRGIALVAHPHPLFGGTMDNKVAQTLARTLVQLNYATYRSNFRGVGETQGEHDAGIGERDDLRAVLDHMRAE----PGQADLP-LVLAGFSFGTFVLSHVAATLREE-------GQEIERMVFVGTA------ASRWDVAP---V-PENTIVIHGETDETVPIQSVYDWARPQEL-----PV--VVIPGAEHFLHR---KLHVLKRIIVDAWR---------------------------     =====>
caucr-CC1867   	MVLRRISLTPCRFRAHRLLRVLQAATSRADHLSALRLRFRKTKRGGQVFRPLKSRAPPSPAEGDDMPDVILTGASGRIEGRYSPGK------TETAPIALILHPHPKAGGHMNHPVSVQLYHLFMKRGFATLRFNFRGVGRSQGEFDAGIGELADAATALDWLQTS------NPAASQTWVAGFDFGAYIGMQLLMR-----------RPETDGFISVSPPTN------MYDFSF-LAPCPASGLFLTGSADTITPPVEVERVVTKLRT-QKGITIDYEVIDKATHFWAE---HLPSVEKSVSDYLDKRLAENPI-------------------     =====>
chrvo-q7nv45   	-------------------------------------------------------------MLKAMNKVGVAGPVGVLDTIYV-PA----Q-GEAAGVAVICHPNPLQGGTHTNKVVQTAAKALSQLGYACYCPNLRGVGDSEGEHDYGNGEVDDAIAVVEYAKSQ------HPGLP-LALAGFSFGGFVAARARARIEAD------------KLLLMGVAVGKYPIPT-P------EV-PADTLVIHGEEDEVIPLSAVMDWARPQNL-----PV--LVFPGAGHFFHG---RLVQLAQMIQRCW----------------------------     =====>
coxbu-CBU1769  	------------------------------------------------------------SYVMTNEDFLIQGPVGQLEVMITRP-----KGIEKSVTGIICHPHPLHGGTMNNKVVTTLAKALDELGLKTVRFNFRGVGKSQGRYDNGVGEVEDLKAVLRWVEHH------WSQDD-IWLAGFSFGAYISAKVAYDQKVA------------QLISVAPPVFY------EGFAS-LTQMASPWLIVQGDQDEVVPFEQVKAFVNQISS-----PVEFVVMSGASHFFHG---RLIELRELLVRNLA---------------------------     =====>
jansc-q28ps8   	-----------------------------------------------------------------MPEVIFPGPEGRLEGRYHPQK------AKDAPIAIILHPHPQFGGTMNNRVVYNLHYAYHQMGFTVLRFNFRGVGRSQGEYDQGIGELSDAASALDYLQSM------NPNSKHCWVAGFSFGAWIGMQLLMR-----------RPEITGFISVSPPAN------MYDFSF-LAPCPASGLIINGTSDRVAKPQDTRILVDKLHE-QKGITITHEEMEGAGHFFED--PHMDPMIESVQSYVRRRLTETTR-------------------     =====>
magmm-q2w2t9   	-----------------------------------------------------------------MPEVIFNGPDGRLEGRYHHGK------SPNAPLALLLHPHPQHGGTMNNKVVYALYHAFVRRGFSTLRFNFRGVGRSQGKFDNGQGELSDAASALDWMQSF------NANASACWVGGFSFGAWIGMQLLMR-----------RPEIDGFVSVAPPAN------VFDFSF-LAPCPSSGLIVHGTNDDLVPEPTVAKLAAKLAT-QRNIKVRYETIEGANHFFGT---HLDALDGMVDSYLAESIVARAPAPPPVAEPELA---VALS-     =====>
marmm-q0aq35   	-----------------------------------------------------------------MPDVIIPGPAGRLEGRYSPSE------DPTAPIALILHAHPLGGGHMENPSVDMMYDVFRKRGFATLRFNFRGVGRSQGSYDQGLGELSDAATVLDWVQGY------NQGARFCWVAGHSFGAWVGMQLLMR-----------RPEIAGFISVAPPTN------MYDFTF-LAPCPASGIIVHGSADKIVPPEDVERVMSKVRV-QKGIEITTEVVPDANHLFSE---HLDVLEGHIETYLESRLPLVEKERSER--TITGKR------     =====>
meslo-MLL0014  	-------------------------------------------------------------MEYFMPEVIFTGPAGRLEGRYQPSK------EKSAPIAIVLHPHPQFGGTMNNKIVYDLFYMFQKRDFTTLRFNFRGIGRSQGEFDHGTGELSDAAAALDWVQSL------HPDSKSCWVAGYSFGSWIGMQLLMR-----------RPEIEGFISIAPQPN------TYDFSF-LAPCPSSGLIIHGDADKVAPPKDVQGLVDKLHT-QKGITITQKTLPGANHFFAN---HADLLIEECADYLDRRLAGELSD-PRPKRLR----------     =====>
messb-q11he8   	-----------------------------------------------------------------MPEVIFTGPAGRLEGRYQPSK------EKNAPIALILHPHPQFGGTMNNKIVYDLFYMFQQRSFTVLRFNFRGIGRSQGAFDHGSGELSDAAAALDWVQSL------HPDSKSCWVAGYSFGAWIGMQLLMR-----------RPEIEGFISIAPQPN------IYDFSF-LAPCPSSGLIIHGSADRVAPAADVQTLVDKLQS-QKGITITQKIIPDTNHFFSN---TSDVLIEECSEYLDRRLRGELAE-PRPKRLR----------     =====>
neig1-q5f9g1   	--------------------------------------------------------------MLKPETIHIPGPAGILETIHI-PS----EQVPARGVAVINHPNPLQGGTNTNKVIQTAAKALSKLGFHCYLPNLRGVGGSEGTHDYGRGETQDCLAVIDYARAQ------HPEAPEFALSGFSFGGYVATFAAQVSIPD------------LLLLIGAAVCHYTDRPEPSA---VPN-VAKTLMIHGAEDEVVEIEKALKWAEPQDL-----PV--ITIAGSTHFFHG---KLIVLRDTILRFAPVCLNG----------------------     =====>
neime-NMB0868  	--------------------------------------------------------------MLKPETIHISGPAGILETIHI-PS----EQVPARGVAVINHPNPLQGGTNTNKVIQTAAKALSKLGFHCYLPNLRGVGGSGGTHDYGRGETQDCLAVIDYARAQ------HPEAPEFALSGFSFGGYVATFAAQARTPD------------LLLLIGAAVCHYTDRPEPSA---VPN-VAKTLMIHGAEDEVVEIGKALKWAEPQDL-----PV--ITIAGSTHFFHG---KLIVLRDTILRFAPVCLNG----------------------     =====>
neimf-a1kta9   	--------------------------------------------------------------MLKPETIHISGPAGILETIHI-PS----EQVLARGVAVINHPNPLQGGTNTNKVIQTAAKALSKLGFHCYLPNLRGVGNSEGTHDYGRGETQDCLAVIDYARAQ------HPEAPEFALSGFSFGGYVATFAAQARIPD------------LLLLIGAAVCHYTGRPEPSA---VPN-VAKTLMIHGAEDEVVEIEKALKWAEPQDL-----PV--ITIAGSTHFFHG---KLIVLRDTILRFAPVCLNG----------------------     =====>
niteu-NE1875   	--------------------------------------------------------------MPNEQKRFVTGPAGRLETVVTLPE------GAPRGLAIVAHPHPLYQGSMDNKIVYILSRAFIEQQYITVKFNFRGVGASEGSYAEGKGEIEDVMAVTQAMREQY--DTGPEPLP-LTLAGFSFGGAVQAHVAQQLKPS------------RLVLVAPSV------ERLQAPPVVDH-ARHILVIQGDQDTIVPLQSILNWAAPQTL-----PV--TVIPGAEHFFHG---KLHVLKNVILQSCSISQAATSLYP-----------------     =====>
nithx-q1qkx5   	-----------------------------------------------------------------MPEVIFTGPAGRLEGRYHPAK------QKNAPIAMVLHPHPQFRGSMNHPIVYQVYYAFVARGFSVLRFNFRGVGRSQGSFDHGTGELSDAAAALDWAQTI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPEPN------RYDFSF-LAPCPSSGLIVHGEKDIVAPAKDVTTLVEKLKT-QKGIVIDQHTIPGANHFFED---RMEPLMETVTDYLDMRLANIR--------------------     =====>
nitwn-q3ss14   	-----------------------------------------------------------------MPEVIFTGPAGRLEGRYHPAK------QKNAPIAMVLHPHPQFRGSMNHPIVYQVYYAFVARGFSVLRFNFRGVGRSQGSFDHGTGELSDAAAALDWAQTI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPEPN------RYDFSF-LAPCPSSGLIVHGEKDIVAPAKDVTTLVEKLKT-QKGIVIDQQTIPGANHFFED---KMEPLMETVTSYLDMRLANIR--------------------     =====>
novad-q2g4i8   	-----------------------------------------------------------------MPAVIFPGPEGRLEGRFQPAT------RPRAPVAMILHPHPQAGGTMNDRITQALYKTFVARGFATLRFNFRGVGRSQGSFDNGIGELSDAAAALDWVQSI------HPEASTTWIAGYSFGALIGMQLLMR-----------RPEIRGFISVAPPAN------MYDFSF-LAPCPASGIIVQGAADTVVTPNAVQKLVDKLRT-QKHITIHHDEIPRANHFFEN---ELDEMMRSVDNYLDMRLSPDCPIR-----------------     =====>
pardp-a1b699   	-----------------------------------------------------------------MPELIFPGPEGRLEGRYHAQA------APDAPIAIILHPHPQYGGTMNNRVVYNLHYAFHRMGFTVMRFNFRGVGRSQGEFDQGIGELSDAASALDYLQAM------NPNSKHCWVAGFSFGAWIGMQLLMR-----------RPEITGFISVAPPAN------MYDFSF-LAPCPSSGLIINGTADRVAPPKDTHALVAKLRE-QKGITITHEEIEGADHFFRDDEVHMKPMIDTVQAYVRRRLTENTR-------------------     =====>
pelub-q4fmn3   	-------------------------------------------------------------MDNKIVEVFIPGPAGRMEAKYYKSE------KITSPIALVLQPHPQYGGTMNNKVVVDTFHTFMENGFSVCRVNFRGVGKSDGEFDNGQGELADAAAALDWLERE------NFDNSQCWVSGFSFGSLIAMQLLMR-----------RPEINRFIAISPQPN------VYDFSF-LSPCPTSGLMIYGKKDELVPLEHITDLDKRLSA-QKGIKVDFQAINDANHFFTK---TEDVLVKCLDKYIKKESALF---------------------     =====>
pseae-PA4440   	-------------------------------------------------------------MSTREIPVSIDGPCGPLEALHLDL-------PDARGVALVCHPHPLFAGTMQNKVVATLQRSARDAGLATLRFNFRGVGQSAGSYGEGIGEIDDAEAAARWLLAR------HPGLP-LTLMGFSFGSCVAGNLAGRLEAQ-------GVGLARLFMIAPPVER------FA---VSLPARCPLTVVQPEDDDVVTPAAVYAWSESLAR-----PHELLRVAESGHFFHG---KLIDLKDLLLPRLQD--------------------------     =====>
psepu-PP1310   	-------------------------------------------------------------MLVRETPLFIDGPSGQLEALYLDV-------ANARGAVLICHPNPVQGGTMLNKVVSTLQRTARDAGYVTLRFNYRGVGQSAGSHDMGAGEVADAEAAAAWLRAR------HPGLP-LVLMGFSFGGFVATSLAGRLETA-------GVELQHLFMIAPAVMR------LTAE-FPMPQRCPLTVVQPDADEVVAPQLVYEWSDSLSR-----PHELLKVAECGHFFHG---KLTDLKDLLLPRLSN--------------------------     =====>
psepu-PP3367   	------------------------------------------------------------MSDTPRNPLLIDGAVGQIELLIDYPD------GPPKGLVLVSHPQPLLGGSPRHIVPLTLARQLRAAGWQVVRPSFRGVGQTQGTHDQGIGEAEDCIAVIRHFNQQ------QPELP-VALVGFSFGAYVFARVACALEGQ----------LQAVALMGLPVGDVPGGRYYEPLP---L-PGDCLLLQGEQDEMAPLANLLQWAGPEQR-----AV--SVYAGANHFFKG---CLGRAAEQVIAHLAQKTGPHRSR------------------     =====>
psesy-PSPTO4430	---------------------------------------------------------------MRETPFFIDGPEGQLEALYQDV-------PDARGVALICHPNPIQGGTMLNKVVSTLQRTARDQGLITLRFNYRGVGASAGTSVAGPGEIDDAQAAAQWLRAQ------HPDLP-MTLFGFSFGGYVAANLGGRLEAQ-------GEKLTHLFLIAAAASR------LQDQ-SVLPHACPLTIIQPEADEVIDPETVYAWSAALQR-----PHELLKVAECGHFFHG---KLTDLKDLLLPRLPN--------------------------     =====>
psyar-q4fs69   	-------------------------------------------------------------------MQLIPAPAGVLEVDALWQQNN-PNDPNTDTVALLCHPNPLFDGTMNNKVVTTMYRFARDNGMHVVRFNFRGVGQSTGEHDYADGEVVDAMTVLQWIAEQ------TS-ARKLWLGGFSFGGYVTARVAEQVLVSPHIWGLDDFEISKIALIAPSVEKND------SSD-IDLPADRTFEIYGNADEVIDPSSMQDFAERLGI-----DV--SIVDGAGHFFHG---RLSELKKLLEQHTDNGDI-----------------------     =====>
psyck-q1qbs9   	-------------------------------------------------------------------MQLIPAPAGVLEVDALWQQDN-SNDPNTDTVALLCHPNPLFDGTMNNKVVTTMYRFARDNGMHVVRFNFRGVGQSTGEHDYADGEVVDAMTVLQWIAEQ------TP-ARKLWLGGFSFGGYVTARVAEQVLVSPHIWGLDDFEISKIALIAPSVEKND------SSD-IDLPADKTFEIYGNADEVIDPDNMQEFADRLGI-----PV--SVVDGAGHFFHG---RLSELKKLLEQHTYNGDI-----------------------     =====>
raleh-q0k038   	-----------------------------------------------------------MAVPSGTEKAQLGGEAGQIEMLVDRPA------GAPRGIAVVAHPHPLLGGSATHKVPHQLAKALVARGFLTVRPNFRGVEGSAGQHDQGSGEAQDMLAVVAHLREA------HPGLP-LALAGFSFGAFVMANAAATLAAR-------SVPIRHLVLAGTPYGTVKAHRSYDTPA---V-PADCLVVHGERDERAELGALFDWARPQGL-----PV--VVVPGADHFFTG---KLPLLVRIVGGYLDRPEAGAAA-------------------     =====>
ralso-RSC0328  	-------------------------------------------------------------MNVHTAERLIPGPVGNIDVSVDLPD------AAPRGLALVGHPHPLFGGTKDNKVAQTLARTFVGLGYATVRPNFRGVGKTEGTHDNGIGEQDDMLAVLDWMRTQAEWSPEVATLP-LALGGFSFGSFVVSQVARRLAEA-------GTPAERLALVGTA------TSRWDVAP---V-PADTIVIHGELDDTVPLAAVLDWARPQEL-----PV--IVIPGADHFFHR---KLHLIRQQIAGAWTPRS------------------------     =====>
rhiec-q2k801   	-----------------------------------------------------------------MPEVIFNGPAGRLEGRYQPSK------EKSAPIALILHPHPQFGGTMNNQIVYQLFYMFQKRGFTTLRFNFRGIGRSQGEFDHGAGELSDAASALDWVQSL------HPDSKTCWVAGYSFGAWIGMQLLMR-----------RPEIEGFMSIAPQPN------TYDFSF-LAPCPSSGLIINGEADKVAPEKDVNGLVEKLKT-QKGILITHRTVANANHFFNG---QVETLMGECEDYLDRRLNGELVPEPAAKRIR----------     =====>
rhil3-q1mg51   	-----------------------------------------------------------------MPEVIFNGPAGRLEGRYQPSK------EKSAPIALILHPHPQFGGTMNNQIVYQLFYMFQKRGFTTLRFNFRGIGRSQGEFDHGAGELSDAASALDWVQSL------HPDSKTCWVAGYSFGSWIGMQLLMR-----------RPEIEGFMSISPQPN------TYDFSF-LAPCPSSGLIINGEADKVAPEKDVNGLVEKLKT-QKGILITHRTVANANHFFNG---QVETLMGECEDYLDRRLNGELVPEPAAKRIR----------     =====>
rhime-R01737   	-----------------------------------------------------------------MPEIIFNGPAGRLEGRYQPSK------QKSAPIAIILHPHPQFGGTMNNQIVYQLFYMFQKRGFTTLRFNFRGIGRSQGEFDHGAGELSDAASALDWVQSL------HPDSKSCWVAGYSFGAWIGMQLLMR-----------RPEIEGFMAVAPQPN------IYDFSF-LAPCPSSGLIINGDSDKVAPEKDVNGLVEKLKA-QKGILITHKTVPGANHFFNG---QVETLMAECEDYLDRRLNGELVPEPAAKRIR----------     =====>
rhop2-q2ivr2   	-----------------------------------------------------------------MPEVIFTGPAGRLEGRYHPAK------QKNAPIAMVLHPHPQFRGSMNHPIVYQVYYAFVARGFSVLRFNFRGVGRSQGSFDHGTGELSDAASALDWAQTI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPEPN------RYDFSF-LAPCPSSGLIVHGEKDIVAPAKDVNTLVEKLKT-QKGIIIDQQTIPGANHFFED---KMEPLMETVTSYLDMRLANVR--------------------     =====>
rhop5-q07mc7   	-----------------------------------------------------------------MPEVIFTGPAGRIEGRYHPAK------QKNAPIAMVLHPHPQFHGTMNHQIVYQCYYAFVHRGFSVLRFNFRGVGRSQGSFDHGTGELSDAASALDWAQSI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPPAN------LYDFSF-LAPCPSSGLIVHGEKDAVVPPKDVNTLVEKLKT-QKGIVIDQQIIPGANHFFDG---KLEPLMETVTSYLDMRLANVR--------------------     =====>
rhopa-q6n701   	-----------------------------------------------------------------MPEVIFTGPAGRLEGRYHPAK------QKNAPIAMVLHPHPQFRGNMNHPIVYQVYYAFVARGFSVLRFNFRGVGRSQGSFDHGTGELADAASALDWAQTI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPEPN------RYDFSF-LAPCPSSGLIVHGEKDIVAPAKDVNTLVEKLKT-QKGIVIDQQTIPGANHFFED---RMEPLMETITSYLDMRLANVR--------------------     =====>
rhopb-q213p5   	-----------------------------------------------------------------MPEVIFTGPAGRLEGRYHPAK------QKNAPIAMVLHPHPQFHGTMNHQIIYQCYYAFVHRGFSVLRFNFRGVGRSQGSFDHGTGELSDAASALDWAQTI------NPEARACWVAGFSFGAWIGMQLLMR-----------RPEVEGFISIAPPAN------LYDFSF-LAPCPSSGLIVHGEKDAVVPPKDVNTLVEKLKT-QKGIVIDQHIIPGANHFFDG---KLQPLMESVTGYLDMRLANVR--------------------     =====>
rhos4-q3j0r8   	-----------------------------------------------------------------MPEVIFAGPEGRLEGRYHPQK------DRDAPIAIVLHPHPQFGGSMNNKVVYNLHYAFYRLGFTVLRFNFRGVGRSQGEYDQGIGELSDAAAALDYLQSM------NQNAKHCWVAGFSFGAWIGMQLLMR-----------RPEITGFVSVAPPAN------MYDFSF-LAPCPSSGLIINGTADRVAQPKDTVTLVGKLHE-QKGITVTHEQIEGADHFFKDEEAHMTPMISKVSDYVKRRLTEGSR-------------------     =====>
ricbr-q1rie6   	-----------------------------------------------------------------MSQIYFNGPEGRIEGIYVKAE------AYNAPVALVLHPHPLHGGDMNNTVVYNAYKVLSEHGYTVLRINFRGVGHSEGNFNNGVGEVIDAGTALDWLQQN------NPNAQSNLVLGFSFGAWIAMQLVMR-----------RPEINNFIAISPPVN------KYDFSF-LSPCPIPGFVLQGDSDSIVSAEAVKDLASKLSKQQAHIKVGCKIISGADHFFRY---KMEEFSKAIGDYLKTLDHSYPQNNNNVNEE-SKSQKKLFLY     =====>
ricco-RC0713   	-----------------------------------------------------------------MPQIYFNGPEGRIEGRYAKAT------APNAPIALVLHPHPLYEGNMNNKVVYNAYKILADNGYTVLRINFRGVGGSQGKFDNGVGEVVDAGAALDWLQQN------NPNAQSNLILGFSFGAWIAMQLVMR-----------RPEINHFIAISPPINT---IHKYDFSF-LSPCPIPGFILQGDNDSIVSADDVKDLANRLSKQQSHIKVDYKIINGADHFFRY---KTEEFSKAINAYLITIQSNYHHHNNNVNEEISKHPKKLFLY     =====>
ricfe-q4ul94   	-----------------------------------------------------------------MPQIYFNGPEGRIEGRYAKAT------SPNAPIALILHPHPLYEGNMNNKVVYNAYKILADNGYTVLRINFRGVGGSQGKFDNGVGEVVDAGAALDWLQQN------NPNAQSNLILGFSFGAWIAIQLVMR-----------RPEINHFIAISPPVNT---IHKYDFSF-LSPCPIPGFILQGDNDSIVSADDVKDLANRLSKQQSHIKVDYKIINGADHFFRY---KTEEFSKAISDYLITIQSNYHHHNNNVNEEVSKSQKKLFLY     =====>
ricpr-y471     	-----------------------------------------------------------------MPQIYFNGPEGRIEGRYAKAT------SPNAPIALVLHPHPLYEGNMNNKVVYNAYKILVDNGYTVLRINFRGVGGSQGKFDNGVGEVVDAGAALDWLQQN------NPNAQSNLILGFSFGAWIAMQLVMR-----------RPEINHFLAISPPVNT---IHKYDFSF-LAPCPIPGFILQGDNDSIVSADDVKDLVNRLSNQQSHIKIDYKIINGADHFFRY---KTEEFSKAINDYLITIQSNYHHHN-NINEDKSKNQKKLFLY     =====>
ricty-q68wq9   	-----------------------------------------------------------------MPQIYFNGPEGRIEGRYAKAT------SPNAPIALVLHPHPLYEGNMNNKVVYNAYKILVDNGYTVLRINFRGVGGSQGKFDNGVGEVVDAGAALDWLQQN------NPNAQSNLILGFSFGAWIAMQLVMR-----------RPEINHFLAISPPVNT---IHKYDFSF-LAPCPIPGFILQGDNDSIVSADDVKDLVNRLSNQQSHIKIDYKIINGADHFFRY---KTEEFSKAINDYLITIQSNYHQHN-NVNEDKNKNQKKLFLY     =====>
xanax-XAC0279  	--------------------------------------------------------MSNPSFPTESAALTLEGPVGPLDVAVDLPE---PDVAAHAVTAIFCHPLSTEGGSMHNKVVTMAARALRELGITVVRFNFRSVGNSAGAFDHGVGEQDDLRAVAEWVRAQ------QPGHT-LWLGGFSFGAYVALRAACSLQPQ------------VLISIAPPAGR------WDFSD-I-QPPAQWLVIQGDADEIVDPQAVYDWLETLEQ-----QPELVRMPDTSHFFHR---KLIDLRGAIQHGVRRWLPAAV--------------------     =====>
xanca-XC6422   	--------------------------------------------------------MSNPLFPTESAALTLDGPVGPLDVAVDLPE---PDVAVQPVTAIVCHPLSTEGGSMHNKVVTMAARALRELGITVVRFNFRSVGTSAGSFDHGDGEQDDLRAVAEWVRAQ------RPTDT-LWLAGFSFGAYVSLRAAAALEPQ------------VLISIAPPAGR------WDFSD-V-QPPAQWLVIQGDADEIVDPQAVYDWLETLEQ-----QPTLVRMPDTSHFFHR---KLIDLRGALQHGVRRWLPATP--------------------     =====>
xanca-XCC0260  	--------------------------------------------------------MSNPLFPTESAALTLDGPVGPLDVAVDLPE---PDVAVQPVTAIVCHPLSTEGGSMHNKVVTMAARALRELGITVVRFNFRSVGNSAGAFDHGEGEQDDLRAIAAWVRSQ------RPGDT-LWLAGFSFGAYVSLRAAGSLAPQ------------VLISIAPPAGR------WDFSD-V-QPPAHWLVIQGDADEIVDPQAVYDWLETLDQ-----QPTLVRMPDTSHFFHR---KLIDLRGALQHGVRRWLPATP--------------------     =====>
xanp2-q26rg7   	-----------------------------------------------------------------MPEVIFPGEKGRLEGRYQPAK------TRNAPIAIILHPHPQFGGTMNNPVVYNLYYQFANRGFSVLRFNFRGVGRSQGSFDHGTGELSDAAAALDWAQSI------NPDARACWIAGFSFGAWIGMQLLMR-----------RPEVEGFISIAAPAN------LYDFSF-LAPCPSSGLFVHGDKDAVVPTSAVQTLVEKLKT-QKGIVIEQQVVPGANHFFDG---KTEDLMGVVGTYLDKRLPGTRKDSKDSAA------------     =====>
xylfa-PD1038   	------------------------------------------------------MAMPNPVLPNTSGTLFLEGPVGCLEVAVDFPA---FNVTTQSPVAIICHPLSTEGGSMDNKVVTMTARALRELGMMTVRFNFRSVGASDGMFDNGHGEREDLRAIAAWVRAQ------RPDST-LWLAGFSFGAYISLLVAEELETQ------------VLISISPPAGR------WDLSH-V-HPPEHWLLIQGDADEVVDPQAVYDWISTLPR-----QPKLIRMPETSHFFHR---KLIHLRDAIQDGVRSWLPQLA--------------------     =====>
xylfa-XF1829   	------------------------------------------------------MGMPNPVLPNTSGTLFLEGPVGSLEVAVDFPG---FNVTTQSPVAIICHPLSTEGGSMDNKVVTMTARALRELGMMTVRFNFRSVGASDGMFDNGHGERADLRAIAAWVRAQ------RPDSA-LWLAGFSFGAYISLLVAEELEPQ------------VLISISPPAGR------WDFSH-V-HPPEHWLLIQGDADEVVDPQAVYDWISTLPR-----QPKLIRMPDTSHFFHR---KLIHLRDAIQDGVRSWLPQLA--------------------     =====>
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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