Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....790..5....800..5....810..5....820..5....830..5....840..5....850..5....860..5....870..5....880..5....890..5....900..5....910..5....920..5....930..5....940..5....950..5....960..5....970..5....980..5....990..5....1000.5....1010.5....1020.5....1030.5....1040.5....1050.5....1060.5....1070.5....1080.5....1090.5....1100.5....1110.5....1120.5....1130.5....1140.5....1150.5....1160.5....1170.5....1180.5....1190.5....1200.5....1210.5....1220.5....1230.5....1240.5....1250.5....1260.5....1270.5....1280.5....1290.5....1300.5....1310.5....1320.5....1330.5....1340.5....1350.5....1360.5....1370.5....1380.5....1390.5....1400.5....1410.5....1420.5....1430.5....1440.5....1450.5....1460.5....1470.5....1480.5....1490.5....1500.5....1510.5....1520.5....1530.5....1540.5....1550.5....1560.5....1570.5....1580.5....1590.5....1600.5....1610.5....1620.5....1630.5....1640.5....1650.5....1660.5....1670.5....1680.5....1690.5....1700.5....1710.5....1720.5....1730.5....1740.5....1750.5....1760.5....1770.5....1780.5....1790.5....1800.5....1810.5....1820.5....1830.5....1840.5....1850.5....1860.5....1870.5....1880.5....1890.5....1900.5....1910.5....1920.5....1930.5....1940.5....1950.5....1960.5....1970.5....1980.5....1990.5....2000.5....2010.5....2020.5....2030.5....2040.5....2050.5....2060.5....2070.5....2080.5....2090.5....2100.5....2110.5....2120.5....2130.5....2140.5....2150.5....2160.5....2170.5....2180.5....2190.5....2200.5....2210.5....2220.5....2230.5....2240.5....2250.5....2260.5....2270.5....2280.5....2290.5....2300.5....2310.5....2320.5....
ailme-d2gtv3   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPA-VDAPARSTGLGWVRG--------KQAHVLG--------S-TVPVNVFLGIPYAAPPLGP-LRFK-----KPKPAL--P---WN-GFR-DATS----YPKL---CLQDSEW-MLSDQHFLK------------VHYPKLEVSEDC--LYLNIYAPAHADSG---SKLP---VMVWLPGGAFE------------------------TGSASI------FDGS-ALAAYEDVL-IVTTQYRLGIFGFFNTGDQ-------HAWGNWAFLDQMAALTWVQENIEFFGGDPRS----------------------VTLFGESAGAISVSSLILSPM-A----KGL--FHKAIMESGVAIIPFL-----RA-PDDERDED-------LQVI--AHIC-----GCNA--------SD-----TMALLQCLRAK----SAEELL-DIN-----------------------------------KKTKSFT-RVVDGFFFPD--EPLDLLTEK-----T-FN--SVPSVI---GVNNHECGFQLPKK--------------------------------------EFPEILGGS--KKSLAL------------------------------------------------------------------------------------HLLQTVLHIPNKYLYLVADQ------------YFSNK---------------------------HSLVEIRDSFLDLLG---DVFFVVPGVVT-ARYHRD-----------------------A--GAPV-YFYEFQ--H-APQCLKD--------------TRPAFVK-ADHS--D-----------------------EIRFVFGGAFLKGDVVM--------------------------------------FEGATEEEK-LLS------------------------------RKMMR-YWANFA--RTGD-PNGEG--------------LPLWPAYSR-SEL-YLKLDLN-VSVG---QKL----KEQEVEFWSD---TLPLI-MSTS-TALPG---PPSPLLSLSL-------------LL-------PFFF-----------------SSAP--------------------------------------------------------------------     =====>
ailme-d2h9c9   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQESASPIRTTHTGQVRG--------SLIHVKD--------T-DVGVHTFLGIPFAKPPLGP-LRFA-----PPEPPE--P---WS-GVK-DGTS----HPAI---CLQDLTF-MKILALKLLNM-----------TLPFTSMSEDC--LYLSVYTPVHASEG---SNLP---VLVWIHGGALV------------------------TGMASM------YDGS-LLAAFEDVV-VVTIQYRLGILGFFSTGDK-------HAPGNWGYLDQVAALRWVQQNIAYFGGDPGL----------------------VTIFGESAGGTSVSSHVVSPM-S----QGL--FHRAIMESGVALLPGL----IASSSDAIS-----------AMA--ANLS-----ACGQ-------------VDSEVLVGCLRDK----TEEEIL-AIN-----------------------------------KLFK-IIPGVVDGTFLPR--HPQELLASA-----N-FQ--PVPSII---GVNSDEYGWIIPLVMNISEAQ-------------------------------------KEM--DRETVKAILQ-----------------------------------------------------------------QV-------------LGM---LTLPPESFDLLMEE------------YMGDS---------------------------GDPQTLRAQFHEMMG---DSVFVIPALQV-AN-FQR-----------------------S--HSPV-YFYEFQ--H-RPSFLK--------------DIRPPHVK-ADHG--D-----------------------ELLFVFGTLPWGAN------------------------------------------VEVTEEEK-LLS------------------------------RKIMK-YWANFA--RNGN-PNGE-G-------------LPHWPVFDQE-EQ-YLQLNTQ-PAVG---RAL----KAHRLQFWTK---TLPQ-KTQELMEAGDK---HTEL-------------------------------------------------------------------------------------------------------------------------     =====>
ailme-g1mdr5   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWLI-AL--V-------------------LTSLTT-PMAWGGRPSSPPVVDTVQGKVLG--------KYVSLEG--------F-AQPVAVFLGVPFARPPLGS-LRFA-----PPQPAE--P---WN-FVK-NTTS----YPPM---CSQDAVA-GQVLSELFTN---RK-------ENIALKFSEDC--LYLNIYTPADLTKK---SRLP---VMVWIHGGGL-------------------------VGGAST------YDGL-ALSAHENVV-VVAIQYRLGIWGFFSTGDE-------HSRGNWGHLDQLAALRWVQENIANFGGNPGS----------------------VTIFGESAGGESVSVLVLSPL-A----KNL--FHRAISESGVALTAALV----KKDMK--DT---------AQQI--AVFAG-----CKT-------------TTSAVLVHCLRQK----TEDELL-ETSLKLKFFAL--------DLFGDPR-----------ENH--PFLPTVVDGVLLPK--MPEEILA-E-----KKFN--SVPYII---GINKQEFGWILPMM---MGY---------------------------------PLSE-GKL--DQKTATSLL---------------WK------------------------------------------------------------SY------SVVRVPEELTPLATEK------------YLGGT---------------------------DDPVKKKDLFLDMLG---DLVFGVPSVTV-ARHHRD-----------------------A--GAPT-YMYEFQ--Y-HPSFSSD-------------M-KPKTVL-GDHG--D-----------------------ELFSVFGAPFLK--------------------------------------------GGASDEEV-RLS------------------------------KMVMK-LWANFA--RSGN-PNGEG--------------LPSWPAY-DQKEG-YLQIGAT-TQPA---QKL----KDKEVAFWTE---LLAKG-AE-EKPPHTE---HVEL-------------------------------------------------------------------------------------------------------------------------     =====>
ailme-g1mfp4   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRSMG-T-VVRSGS---------R-V-QL-WVACLLLAFPATATGSEVTQPEVDTPLGRVRG--------RQEGVKG--------T-DRLVNVFLGIPFAQAPLGT-GRFS-----APRPAQ--S---WE-GVR-DAST----APAM---CLQDLQR-MDNSR---FV-LNGK--------HRLFPISEDC--LTLNIYSPAEATAG--T-RRP---VMVWIHGGSLL------------------------AGAATS------QDGS-ALAAYGDVV-VVTVQYRLGFLGFLSTGDE-------HAPGNWGFLDVVAALRWVQGNISPFGGDPNS----------------------VTISGNSAGSCIVSALVLSPL-A----AGL--FHRAIAQSGIITMPLI----LDSNPRV-----------LAQNF--ADSM-----GCSS--------T-----SSAEMLQCLRQI----TNEEQI-LNQ----------------------------------NT---TAS-YTIDGTFFPK--NPMELLKER-----H-FN--SVPFLV---GVNNDEFGWLILR-------------------------------------GWGFLDKMEQL--SLEDILAMVR-----------------------------------------------------------------PY-----LASMG-----------VPPEVMPSIIDE------------YLGSG---------------------------SNAEAKRNAFQDILA---DIMVILPSLNF-SRNLRD-----------------------S--GVPV-FFYEFQ--H-RPSSFMK--------------FKPEWVR-ADHG--A-----------------------EIAFMFGGPFLTDESSLLA------------------------------------FPEATEEEK-PLS------------------------------LTMMA-QWTQFA--RTGD-PNGEG--------------LPPWPPFNQ-LEQ-YLEISLT-PQVG---QKL----REDRMRFWEE---TLPVK-IEQWQQMRKGRKAQGEL-------------------------------------------------------------------------------------------------------------------------     =====>
anapl-thioe    	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAT-----EKNTL---LS-LIL-TAGITALVATGQKAEQPEVVTNYGSVRG--------YQVKVNA--------A-ERSVNVFLGLPFAKPPVGP-LRFS-----EPQPPE--P---WK-GVR-DAAS----YPPM---CLQDKVL-GQYLS---DAITNRK-------EKVRLQISEDC--LYLNVYTPVSTEEQ--E-KLP---VFVWIHGGGLV------------------------SGAASS------YDGS-ALAAFDNVV-VVTIQYRLGIAGYFSTGDK-------HARGNWGYLDQVAALQWIQENIIHFRGDPGS----------------------VTIFGESAGGVSVSALVLSPL-A----KGL--FHKAISESGTAVRI-L----FTEQPEE-----------QAQRI--AAAA-----GCEK--------S-----SSAALVECLREK----TEAEME-QIT--------------------------------L-KMPPMFIS-ASLDGVFFPK--SPRQLLSEK-----V-IN--AVPYII---GVNNCEFGWILPR-------------------------------------MMKFPEFTEGL--EKDVARQVLQ-----------------------------------------------------------------STL--AL-SFKG-----------APSDIVDLVYNE------------YIGVA---------------------------ENRAQVRDGLLDSIA---DPLFVFSAVEV-ARHHRD-----------------------A--GNPV-YFYEFQ--H-RPSSAAG--------------VVPEFVK-ADHA--D-----------------------EIAFVFGKPFLAG--------------------------------------------NATEEEA-KLS------------------------------RTVMK-YWTNFA--RNGN-PNGEG--------------LVHWPQYDM-DER-YLEIDLT-QKAA---KKL----KERKMEFWMQ---LTEQI-MSDR---RRK---HTDL-------------------------------------------------------------------------------------------------------------------------     =====>
anoca-h9g4c9   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SALEE-A-PVS----------------VGR--PLTGLLP--LSPSPGSVRPTVSTRLGRLRG--------TLLSVEG--------A-PAPIKAFLGVPFAKPPLGT-LRFA-----PPEPPE--P---WS-HLR-DATS----QPPM---CLQDVSW-MQGMS---HEL-NML--------IPNVSASEDC--LYLNIFTPNTEA------KLP---VLVSIHGGGLI------------------------VGFASM------YDAP-ALSAFENVV-LVTLQYRLGIPGFFSTGSK-------EAPGNWGLLDQVAALRWVQENIEAFGGDPTS----------------------VTIMGVSAGGFSVGVQVLSPL-S----RGL--FHRAISDSGVALLDIL----AAKNPGAMV---------Q--TV--ANVS-----GCEN--------S-----SPAALVRCLRSK----TEEELA-VLNIQ-----LCQ--------------------------IFGMAL-AVVDGEFLPK--APEKLLAAK-----E-FS--DVPYLI---GITNHEYGWALPQ-------------------------------------SGLFVSITEVM--DRQAVTAAFQ-----------------------------------------------------------------ESA--PVLN--------------LPVEATQRALKE------------YVGET---------------------------EDPRELRAQFLDYMG---DVMFLLPAVRA-AIAHRE-----------------------LDSGAPV-YFYQFQ--H-PPSIARD--------------IRPAYVK-ADHA--D-----------------------QVAFVLERLWDG----S--------------------------------------RGEYTEEEK-RLS------------------------------KTVMR-YWANFA--RSGN-PNGQG--------------LVEWPRYDQ-KEG-YLELGLE-PRGA---QKL----KQGKVDFWLK---TLPEQ-MKRETAKQET---HREL-------------------------------------------------------------------------------------------------------------------------     =====>
anoca-h9g5m7   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AR---CLQDLSW-MQELN---QGL-NLTL-------PH-LPLSGDC--LYLNVFTPDTE------ATLP---VSRPVHGGALV------------------------VGSASF------YDAR-GLAALEGVVVVVVLQYRLGIPGFFGTGSK-------EAPGNWGLLDQVAALRWVQENIKAFGGDPTS----------------------VTTMGESAGAFSVGVQVLSPL-S----RGL--FHRAIAESGVALLPSLFV--RSPGAMV-Q-------------------------------------EG-----PASLPGCSRCGLDGPSHSGLT-EP-------------------ARGGVA-----------HPGWLGQ-TVRRGRRG-Q--DAWTTVGRP--------S--QLAWAF------SFGPGWAMVGR---------------------------------------PRSEGEGG--GGGA----------------------------------------------------------------------------------ILPGARQR-----------PRDHG------------ATGPEDMDSPTWDGGPG------------VSSKDRAKVSFYLLVYWL---QTMTSPPPLSF-FKKG-------------------------S--GAPV-YFYEFQ--H-RPSIFRD---TKP--------DF---VK-SDHG--D-----------------------EVTFVLGTLFLSSDDS--------------------------------------PFGEHTEEEK-RLS------------------------------KTVMR-YWANFA--RSG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoca-h9gb75   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSLSA-F-PSI----------------LSRNFPCNVLLCQLSALVCRSAHPTVSTRLGRLQG--------TLLSVED--------A-PVPVKAFLGVPFAKPPLGS-LRFA-----PPEPPE--P---WS-HVR-EAAS----QPPMFARCLQDVSW-MEGIG---QAL-NVT--------LPKLPISEDC--LYLNVFTPDTEA------KLP---VLVWIHGGALI------------------------MGCAYF------YNAP-GLSALENVV-VVVLQYRLGIPGFFSTGSK-------EAPGNWGLLDQVAALRWVQENIEAFGGDPTL----------------------VTIMGESAGGFSVGVQTLSPL-S----RGL--FHRAISESGVALVPSL----FEKSPGDMI---------Q--TV--ANVS-----GCEN--------S-----SPSALVRCLRSK----TEEELA-ALNIQ-----LCQ--------------------------VLGVIP-AVVDGEFLPK--APGELLAAK-----E-FS--DVPYLI---GINNHEYGWILPQ-------------------------------------SGTFRSIMEGM--DRQVVTAAFQ-----------------------------------------------------------------QSA--PILK--------------IPVEATQRALEE------------YVGET---------------------------EDPQELRAQFQDFMG---DVIFGLPSVRA-ARAHR-------------------------DSGAPV-YFYEFQ--H-RPSIFRD--------------IRPAYVK-ADHG--D-----------------------EVPFVLGALFSSNKDSP--------------------------------------FGEYTEEEK-RLS------------------------------KTVMR-YWANFA--RSGN-PNGQG--------------LVEWPRYDQ-RES-YLELGLE-QRGA---QKL----KQSKVHFWLE---TLPEQ-MRGERRTEEEKRTHQEL-------------------------------------------------------------------------------------------------------------------------     =====>
anoca-h9gcs3   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVRPTVSTRLGRLRG--------TLLSVEG--------A-PAPVKAFLGVPFAKPPLGT-LRFA-----PPEPPE--P---WS-HLR-DATS----QPPM---CLQDVSW-MQVMA---HAL-NIV--------PPNVSASEDC--LYLNVFTPDTEA------KLP---VLVSIHGGGLI------------------------AGSASM------YDTP-ALSAFENVV-LVVLQYRLGIPGFFSTGSK-------EAPGNWGLLDQVAALRWVQENIEAFGGDPTS----------------------VTIMGESAGGFSVGVQVLSPL-S----RGL--FHRAISESGVALLNIL----AVKDLRAMV---------Q--TV--ANVS-----GCEN--------S-----SPAALVRCLRSK----TEEELA-ALNIQ-----LCQEEITSNIYIY----------VST-QQVFGSAL-AVVDGKLLPK--APEELLAAK-----E-FR--KVPYLI---GINNHEYGWTLPQ-------------------------------------SGLFVSITEVM--DRQAVTAAFQ-----------------------------------------------------------------ESA--PVLN--------------IPVEATQRALKE------------YVGET---------------------------EDPRELRAQFLDYMG---DVMFLLPSVRT-ARAHRE-----------------------LDSGAPV-YFYQFQ--H-RPSIFRD--------------TRPVYVK-ADHV--D-----------------------QVIFVSGTPL------L--------------------------------------RREYTEEEK-RLS------------------------------KTMMR-YWANFA--RSGN-PNGRG--------------QVKWPRYDQ-KEG-YLELGLE-PRGA---QKL----KQDKVDFWLK---TLPEQ-MREETARGKD---TPR--------------------------------------------------------------------------------------------------------------------------     =====>
anoca-h9ggh4   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MW----------------LGGGVSKGQGRV--LAGGQRSVRPTVSTRLGRLRG--------TLLSVEG--------A-PAPVKAFLGVPFAKPPLGT-LRFA-----PPEPPE--P---WS-HLR-DAAS----QPPM---CLQDVSW-MQGMA---HAL-NIV--------PPNVSASEDC--LYLNVFTLDTEA------KLP---VLVSIHGGGLI------------------------AGSASM------YDVP-ALSAFENVV-LVVLQYRLGIPGFFSTGSK-------EAPGNWGLLDQVAALRWVQENIEAFGGDPTS----------------------VTIMGASAGGFSVGVQILSPL-S----RGL--FHRAISESGVALLDIL----AVKNPGAMV---------Q--TV--ANVS-----DCEN--------S-----SPAALVRCLRSK----TEEELA-ALNIQ-----LCQK---PQIYIF----------IST-QQIFGMAL-AVVDGEFLPK--APEKLLAAK-----E-FS--NVPYLI---GITNHEYGWAFPR-------------------------------------SGILLSTPEVM--DRQAVTAAFQ-----------------------------------------------------------------ESA--PVLN--------------LPVEATQRAMEE------------YLGET---------------------------EDPNELRAQFLDYMG---DVIFLLPAVRA-ARAHRE-----------------------LDSGAPV-YFYEFQ--H-PPSIFRD--------------TRPAYVK-ADHG--D-----------------------QVTFVLGTPL------L--------------------------------------RREYTEEEK-RLS------------------------------KTMMR-YWANFA--RSGN-PNGQG--------------LVEWPRYDR-KEG-YLELDLE-PRGA---QKL----KQGKVDFWLK---TLPEQ-MKRETAEQET---HREL-------------------------------------------------------------------------------------------------------------------------     =====>
anoca-h9ghc5   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLLL-L-LSF----------------VGRG--LTVLLA--LSPSPGSARPTVSTRLGRLRG--------TLLSVEG--------A-PAPVKAFLGVPFAKPPLGA-LRFA-----PPEPPE--P---WS-HLR-DAAS----QPPM---CLQDLSW-MPGMI---QTL-NVM--------PPNVSASEDC--LYLNVFTPDTEA------KLP---VLVWIHGGALL------------------------VGSASL------YDAP-ALSAFENVV-VVVLQYRLGIPGFFSTGSK-------EAPGNWGLLDQVAALRWVQENIEAFGGDPTS----------------------VTIMGESAGGFSVGVQILSPL-S----KGL--FHRAISESGVSLLSGI----FVKSPGDMV---------QLKTV--ANVS-----GCEN--------S-----SPAALVRCLRSK----TEEELA-ALNIQ-----LCQ--------------------------VLGMVP-AVVDGEFLPK--APEEMLAEK-----E-FS--NVPYVI---GMNNQEYGWVIAQ-------------------------------------SPILPSLTEGM--DRQAVAAAFQ-----------------------------------------------------------------ESA--PVLK--------------LRLEVTQRALEE------------YLGET---------------------------EDPQELRAQFQDFMG---DVMFLLPSVRA-ARAHR-------------------------DSGAPV-YFYEFQ--H-RPSIFRD--------------TKPAFVK-ADHG--D-----------------------EVAFVLGTPFLSSKDSP--------------------------------------LGEYTEEEK-RLS------------------------------KTMMR-YWANFA--RSGN-PNGHG--------------LVEWPQYDQ-KEG-YLELGLE-QRGA---QRL----KQSRVHFWLK---TLPEQ-MRGETAEGKT---HQEL-------------------------------------------------------------------------------------------------------------------------     =====>
bovin-e1bn79   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGEWVHPG------------------Q----TLIWAV--W-VLA----------------------------AATKGPATADAPARHTNLGWVQG--------TQASVLG--------N-DMLVNVFLGVPYAAPPVGP-LRFA-----KPEPLL--P---WD-GFL-NATS----YPKL---CFQNSEW-LFTDQHILK------------VHYPKFRVSEDC--LYLNIYAPAHAETG---SKLP---VMVWLPGGAFE------------------------TGSASI------FDGS-ALASYEDVL-VVTIQYRLGIFGFFNTGDE-------HARGNWAFMDQVAALIWVQENIEFFGGDPRC----------------------VTIFGESAGAISVSSLILSPM-T----KGL--FHRAIMESGVAIIPYL-----KA-PDYERNDD-------LQTI--ASIC-----DCSA--------SD-----SIALLQCLRAK----SSKELL-SIN-----------------------------------QKTKSFT-RVVDGLFFPN--EPLDLLAQK-----L-FH--LVPSII---GVNNHECGFLLPMK--------------------------------------EFPEILWGS--NKSLAL------------------------------------------------------------------------------------QLIHSVLHIPVQYLYLVANE------------YFHNK---------------------------HSLVDIRNRFLDLLG---DVFFVIPGLVT-AQYHTD-----------------------A--GAPV-YFYEFQ--H-RPQCLKD--------------RKPSFVK-ADHT--D-----------------------EIRFVFGGAFLKGNIVM--------------------------------------FEEATEEEK-GLS------------------------------RKMMR-YWANFA--RTGN-PNGKG--------------LPLWPAYRQ-SEE-YLQLDLN-ISVG---QRL----KELELKFWTE---TLPLM-MTSS-GALLA---SLSSSTFLFL-------------LL-------PFIF-----------------SFAP--------------------------------------------------------------------     =====>
bovin-est8     	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN-W------------------ILCLSLTLLLVVQT--AWGALHTKEPLADTKYGTLRG--------KQIHVGK--------T---PINVFLGVPFSKPPVGA-HRFA-----APEPPE--P---WE-GIR-DATT----YAPV---CLQES-W-GQVTS---MYFNTHK-------RYKWLHFSEDC--LYLNVHAPVRARG---DPLQP---VMIWFPGGAFL------------------------VGSAST------YDGS-ELAAREKVV-VVVLQHRLGILGFLSTGDS-------QARGNWALLDQIAALRWVQKNIEAFGGDPGC----------------------VTLFGQSSGAMCISGLMTSSL-A----RGL--FHRAISQSGTAVFQNF----ITPDPLK-----------VAKKI--AQLA-----GCNH--------N-----STKILVDCLRTL----SGAEVM-RVSQKMRFFKL-----------H--------SQEDP-QKVVWFMS-PVVDGVVFQD--NPIVLLTQG-----Q-VA--PVPYLL---GVNNLEFNWLLPF-------------------------------------IMKFPMSH--L--RKETIAKLLW-----------------------------------------------------------------STS--TLLN--------------VTKEQLPLVMEE------------YLRD-VD--------------------D----HDQKMLQKHVMDLAA---DATFVYSTLQA-AHYHHN-----------------------A--GFPV-YLYEFE--H-YAP-GTI--------------VKPRTDG-ADHG--D-----------------------EIGFIFGSPFSKG--------------------------------------------HSSNKEK-ALS------------------------------LQMMK-YWANFA--RTGN-PNGGK--------------LPYWPRYNK-DEK-YLQLDLT-TRVG---VML----REEKMAFWKR---LHQN--------------------------------------------------------------------------------------------------------------------------------------------     =====>
bovin-f1mi11   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRSMG-T-VVRTGS---------R-A-LV-GVACLLLAFSATDTGPGVTQPEVDTPLGRVRG--------RQVGVKG--------T-DHLVNVFLGIPFAQPPLGP-HRFS-----APRPAE--S---WE-GVR-DASR----AHAV---CPQDPER-MNNSR---FT-LDGK--------HQTFPISEDC--LILNIYSPAEAPSG--A-GRP---VMVWFHGGSLV------------------------TGTATS------HDGS-ALAAYGDVV-VVTVQYRLGFLGFFSTGDK-------HAPGNWGFLDVVAALRWVQGNITPFGGDFNS----------------------VTIFGESSGASVVSALVLSPL-A----AGL--FHRAIAQSGIITVPGL----LDPNPWL-----------LAQTL--ADSL-----ACNS--------D-----SSAEMVQCLRQK----TIKEMI-LAYKS--------------------------------KK---IAS-YNIDGTFFPK--SAEELLRER-----Q-FP--SVPFLF---GFNNHEFGWLIPR-------------------------------------GWGFLDKMDQL--SLEDMLAILR-----------------------------------------------------------------PS-----LTNMD-----------VPTEVMPTIIKE------------YLGSS---------------------------SDGQAKREALQELLS---DIIITLPMLQF-ARDLQD-----------------------S--GVSI-FFYEFQ--H-RPSSFAK--------------IKPAWVQ-ADHA--A-----------------------ELTFMFGGPFLTDESSMLA------------------------------------FPEATEEEK-QLS------------------------------LTMMA-QWTNFA--WTGD-PNGKG--------------LPLWPPFNH-AEE-YLEISLV-PRVN---QKP----REARMQLWAE---ILPTK-FGQWQQKQKGKKVQEEL-------------------------------------------------------------------------------------------------------------------------     =====>
bovin-q2kj30   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWLF-GL--V-------------------LTSIST-FTAWAGQPPSSPVVDTAQGRVLG--------KHVSLKG--------F-AQPVAVFLGVPFAKPPLGS-LRFA-----PPQPAE--P---WT-FVK-NTIS----HPPM---CSQDPVG-AQLFSDLFTN---RK-------ENISLTFSEDC--LYLNIYTPADLTKR---SRLP---VMVWIHGGGLV------------------------VGGAST------YDGL-ALSARENVV-VVTIQYRLGIWGFFSTGDE-------HSRGNWGHLDQVAALHWVQENIANFGGDPGS----------------------VTIFGESAGAESVSILVLSPL-A----RNL--FHRAISESGVALTSTLV----KRDSK--VA---------AEQI--AAFAG-----CKT-------------ITSAVLVHCLRHK----TEDELL-EVTQKMNFFTL--------VLYGDPT-----------ETY--PFLPTVVDGVLLPK--MPEEMLA-E-----KNFN--TVPYIV---GINKQEFGWILPLF---MRY---------------------------------PLSE-DKL--DQKTATSLV---------------WY------------------------------------------------------------SY------PILSIPEELAPVATDK------------YLGGT---------------------------DDPVKKKGLFLDLIA---DVMFGVPSVNM-ARRHRD-----------------------A--GAPT-YMYEFR--Y-HPSFSAE-------------L-KPKTVM-GDHG--D-----------------------ELFSVFGAPFLK--------------------------------------------DGASEEEI-NLS------------------------------KMVMK-FWANFA--RNGN-PNGEG--------------LPHWPVY-DHKEG-YLQIGVN-TREA---EKL----KDKEVAFWNE---LLSRE-VA-KKAPHLK---HVEL-------------------------------------------------------------------------------------------------------------------------     =====>
bovin-q3t0r6   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPDGPRLRLRAVA-----F-GF-------------LL-----------------------LLV----PGQGQDSTRPVRTTHTGKVQG--------SLVYVNN--------A-DVGVHTFLGIPFAKPPVGP-LRFA-----PPEPPE--S---WS-GVK-DGTS----QPAK---CPQDADG-MKSM--ELWNV-----------TLPSTSMSEDC--LYLNIHTPAYSHEG---SNLP---VMVWIHGGGLV------------------------LGMASM------YDGS-ALAAFGDVV-VVVIQYRLGLLGFFSTGDK-------HATGNWGYLDQVAALRWVQQNIAYFGGDPGR----------------------VTIFGESAGGISVSLHVISPM-S----QGL--FHGAIMESGVALLPGL----TINSSDKVA-----------KVV--ANLS-----ACGQ-------------VDSEALVDCLRHK----NEEEVL-AIN-----------------------------------KLVK-IIPGVVDGIFLPK--HPLELLASD-----D-FQ--PVPSII---GVNNDEYGWIIPLSVNNSDTR-------------------------------------REI--SRESVRNALQ-----------------------------------------------------------------EL-------------STM---TTMPPEFGELLMEE------------YIEDS---------------------------EDHQTLQNQLHEIMG---DYLFVIPALQV-AM-FHR-----------------------S--HAPV-YFYEFQ--H-QSSFFK--------------DVRPSSVR-ADHG--D-----------------------EVLFLFRN----EQ------------------------------------------IQFTEEEE-LLS------------------------------RKMIK-YWANFA--RNQN-PNGE-G-------------LPHWPMFDQE-DQ-YMQLNTQ-PAVG---RAL----KAHRLQFWMK---TLPQ-KTQELMETKEK---HTEL-------------------------------------------------------------------------------------------------------------------------     =====>
bovin-q5myb8   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLV-AL--V-------------------LTSLAI-STAW-GLPPSPPIVDTAQGRVLG--------KYVSLKG--------F-AQPVGVFLGIPFAKPPLGS-LRFA-----PPQPAE--P---WT-FVK-NTTS----YSPM---CSQNAVL-VEMTSDLISN---GM-------ETVKTKFSEDC--LYLNIYTPADLTKR---SRLP---VMVWIHGGALL------------------------TGGASS------CDGL-VLSAHENVV-VVTIQYRLGIWGFFSTGDE-------HSRGNWGHLDQVAALHWVQENIANFGGDPGS----------------------VTIFGGSAGAESVSVLVLSPL-A----KNL--FHRAISESGVALIPGLV----KKDSK--AE---------AKRI--AAFAG-----CKT-------------ITSAVLVHCLRQK----TEDELL-EITQKMNFFTL--------NFLGDPT-----------KTY--PFLPTVVDGVLLPK--MPEEMLA-E-----KNFN--TVPYIV---GINKQEFGWILPLL---MGF---------------------------------PLTA-GKM--DQEMATSFV---------------WK------------------------------------------------------------SY------PILNIPEELAPVATDK------------YLGGT---------------------------HDPVQKKDLLLDLIA---DGLFGVPSVNT-ARYHRD-----------------------A--GVPT-YMYEFQ--Y-RPRFSSE-------------L-KSKTVI-GDHG--D-----------------------EQSSVFGIPVLQ--------------------------------------------DGASEEEI-NLS------------------------------KMMMK-FWANFA--RNGN-PNGKG--------------LPHWPAY-DQKEG-YLQIGVN-TQAA---EKL----KSEKVAFWNE---LLSQE-AT-KKAPRSK---HVEL-------------------------------------------------------------------------------------------------------------------------     =====>
brafl-b6kxq9   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTTAVCSSLVWWWIL-----------L--VTCPGLPSGR-------------PDDSPLHDP----PTDQGAA---------RASGETDGR--------------------------------GMLKSR------RTIYAMQTTAVCSSL--V-----WWW-ILLVTCPGLPSGRPDDSPLHDPPT--DQ-----------DEDVLASTVSGSLRG--------RTER-------VTD-S-RTQVYMFLGVPYARPPLGE-LRFH-----APLPHP--P---WT-GVR-LGVL----GFS---------------------------------------------------------------------------GIGG----------------------------------------------------------------------------------QWNVGFLDQISALRWVQHNIHAFGGDPGR----------------------VTIAGQSAGGLSVGLLVLSPL-T----DGL--FRRAISQSGAATTLPT--------NMNRDQTV-------NRFV--LLSG-----MCR-------------HLSPPETLECLR----NASIEDFV-----------------------------------KV-RPL-TAWNQPVVDGSFLPD--QPRTLLKN------GPAK--NIEYLM---GVTNHELGHIVAQD--------------------------------------SSWHFNTFE--KDRDQMR----------------------------------------------------------------TTISLG-YGNYFQCF----KWG------------VDLK-------------KFI-----------------SD-------PLLDLYMAEQDPLMQVLG---DIIMTAPTVNT-ARYRTD---------------------------TPV-YLYEFQ--H-RPSWHH-----------GK----PGHVK-ADHG--D-----------------------ELLFVFGAPFFDWPRDPA-----------------------------DPAWRV----NFTEGER-VLSR------------------------------KILT-YWTNFV--KTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-b6m1r8   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENC--LHLNIYTPSLSG-----NSLP---VMFWIHGGGFT------------------------GGSSDL------YRGE-ALSVHQDVV-VVTINYRLGVLGFLPTPLA-------NATGNFGLLDQVRALEWVRDNIANFGGDPDK----------------------VTIFGESAGGISVSLLILSPL-A----EGL--FRRAISESGVAITVP-----DEDAMLSITSSV-------------GRSL-----NCTD--------DV-----NANMIDCIRS----KSVESIL-TV-------------------PF-------------------SVY-PVVDHHFLPE--APMALLQAG-----R-FS--KVDYLL---GINNDEMGFILTLP-------------------------------------LFPDL-NNGM--THEQRFLGTS-----------------------------------------------------------------YLVDTVAM-F--------------------APVII------------FPEGKTY-------------------------YDPVSIRQQYFDSAK---DYYFTAPTVSV-ANVQSA-----------------------Q--SVKV-YQYQFQ--H-RPSVFWF----KP--------PY---VQ-ADHG--D-----------------------EIMFVLGTPLVLIMPG---------------------------------------VELFTEEEK-KLS------------------------------LDMMA-YWANFA--RTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xq93   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFFIHGGGLF------------------------SGSGAQ------YDGR-ALAAMGNIV-VVIINYRLGILGFSGIGGQ----------WNVGFLDQISALRWVQHNIHVFGGDPGR----------------------VTIAGQSAGGGSVGWLVLSPL-T----AGL--FRRAISQSGAATTIPT----QNTDY----------------------------------------------------------------------------------------------------------------------------TM--HPRTLLKNG-----S-AR--NIEYLM---GVTNHELGHAISQDWD----------------------------------F------SGEE--DRDQIRSIIK-----------------------------------------------------------------AGYRDYFQ----------------------------------------------------------------------------------------------------------------------------------------------FQ--H-RPSWHH----SKP--------GH---VK-ADHG--D-----------------------ELLFVFGAPFFDWPRN--PA-------------------------DPA------WRLNFTEEER-VLS------------------------------RKIMT-YWTNFV--KTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xqm2   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLV--------------------------VVLTSVSGQDSPTRTTASGDIAG--------FTSVAD-----------GRTVENYFGIPYAAPPTGN-LRFS-----PPQPVQ--S---WE-GVR-NASV----FGNE---CVQTS--------------------------PG-GPMSEDC--LYLNVWVPQQGA--Q-SQVLS---VVVYIHGGAFQ------------------------SGSGNK------EEGADWLAAVGDVI-VVAMNYRLNVFGFLSTGDR-------NSPGNYGLMDQRAAIVWVKENIHNFGGDPDS----------------------ITLYGLSAGSIAVSHQMLSPK-N----NGL--FSRVICESGVATGPGT----INYHPLESVRKL-------------CNVM-----NCTG--------DD-----PAGMVTDLRA----ADPVQLT-NA-------------------AA--------------TFTGKYWA-PVIDGDFIPE--EPLHLLESG-----A-LQ--NRDLLL---GSNDDEGGYLFGDPGF----------------------------------L---AVNNVPM--V--------K-----------------------------------------------------------------GLLQV------TFPGFFT-----------EVKVEH------------FIPPRNIFTLTYD-YDM------------WNEEDPASLRRSLVDLYG---DFTYVANTVQT-ANIYSK-----------------------R--NYTT-YMYQFA--H-RLSNSP-----FP--------PG---VG-ASHA--N-----------------------NHFFIFPSSD--------------------------------------------FLERATVDEK-NLM------------------------------QTMIK-LWTNFA--KTGN-PNSPA----------DTTLPVEWPKYLPSTKQ-YLRLTAN-LASDSVQSNL----RPKHTFFWTK---TAP---------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xut6   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEERKNLLNEIFLKEFLWALFKR--MLNEKVD-----------EMVMSTD-EDDSM-------------AEENR---------------------------------------------IRLK-EIFLKEF-------------------LMAL-------------SKERFNEAV----------------------EKILMPTDEDKEHNSE----TPSRGEAIGEETAYVYDPRPGRRNNYKYRGHEK--HSMTPQRVKRLGR------RLFRKL-------KE--RWVTSP--W-IDHPR---------------------KV---GGLAFPIEEDGPTVHTQYGDVRG----------MY----------VE-DLEGVIFFGLPFGEPPVGE-FRWK-----PPRQYS----RSWAPKVR-DGTV----PGPG---CYQSRCG-PND-----------DDSTFECPR--DRKVSEDC--LYLNIFAPRTILNS-TAAKLP---ILFWIHGGEN---------------------EQG-SGSAYL------YDGRF-LANKTNTI-VVTTNYRLAAFGYLVAGQ-----GEDAATGNYGLLDQAAALRWVKENIGSFGGDKNR----------------------VTVFGQSTGSDATSTLLINPKF-----ADL--FQQAIMLSVPLTIPHK--------SRWEALRL-------GDHL--ADEL-----GCP-----------------NGDMKCLRSK----NSSAL-QAGLDSMGTFFSNPY-----RPLE----------------VSVKWG-PIVDGDIVPG--PTVDSFA------KGHFQ--SKPFII---GTTTEEAVLYIYSLYN------------------------------------KP------V--ASKV---TLY----------------------------------------------------------------------AIYAAFV--HLKAA-----------EVAKE------------YPT-----------------ET---------NTSD--YRPLLSKGVT---DWVFTCPTRNV-IRSAVRKGNTNVW---------LYVFDHVW--SFPHLWDYQ-----------------------------KNCNGHVCHA--E-----------------------DLPFVFQTTRLP--VT---------------------------------------NMTMTAEEQ-KMA------------------------------DAIAY-YYGNFA--HTGD-PNQPSRDAAETTGMTMSWTATTWPRYNQEGNFACLNISTP-HTSLIHDYQK------DKCDFWDRMD-VYNL--------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xut7   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEEWKDHLNEIFLKEFLRAPFKE--MFIEIIN-----------EMLMTTV-EDDSV-------------AEERENLLKKIFLKEYKLLRVFSKGM-------LNEIVNEMVISTDEERNNLLK-RIFLKEF-------------------LKKL-------------SKERFNEFV----------------------DKVLLSTDEDKEHTSP----SEKATE-EETTHTYMYNPVPGKHK--KYRDDEK--HSTTLQRMKRLGR------RLCRKL-----GLKE--GLLTSS--W-NDHPR---------------------KV---GGLAFPIEEDGPVVRTQYSDVRG----------LY----------VE-DLEGVIFFGLPYGEPPVGE-FRWK-----PPRQYN----RSWAPKVR-DGTV----PGPG---CYQSRCG-PND-----------GDDVFQCPR--DRKVSEDC--LYLNIFAPRTILNS-AAAKLP---ILFWIHGGEN---------------------EQG-SGSAYF------YDGRF-LSNKTNAI-VVTTNYRLAAFGYLVAGQ-----GEDAATGNYGLLDQAAGLRWVKENIGSFGGDKNR----------------------VTVFGQSTGSDATSTLLISPKF-----ADL--FHHAIMLSVPLTIPHK--------SRWEALRL-------GDHL--ADKL-----GCS-----------------HGDMKCLRSK----NSSAL-QAGLDRMGTFFSNPY-----RPLE----------------VSVKWG-PVVDGDIVPG--PTVDSFA------KGHFQ--SKPFII---GTTSEEAVLYIYSLYN------------------------------------KP------V--TSLV---TLY----------------------------------------------------------------------AIYAAFV--HLKAV-----------EVSIE------------YPT-----------------ET---------NTSD--YRPHMSKLTT---DWVFKCSTRNV-IRSAVRKGNTNVW---------LYVFDHVW--SFPHLWDYQ-----------------------------KNCNGHVCHA--E-----------------------DLPFVFQTTRLP--VT---------------------------------------NMTMTAEEQ-KMA------------------------------DAIAY-YYGNFA--HTGD-PNQPSRDAAETTRMTMPGTATTWPKYNQEGNFPCLNISTP-STSLIHDYRK------DKCDFWDRMD-VYNL--------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xx26   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVWLHGGGLA------------------------IGSADT------YPAE-IPTSLNNVV-MVTINYRLGNLGFLPTRDA-------ETDGNVALMDMAKALQWVQANIRNFGGDPDR----------------------VTIFGQSGGAWGVSLLVMSPE-T----RGL--YRRAISQSGVAGLGA-----SRRGDTTKTETL-------------AASL-----NCTT--------TS-----FDDMMSCLRS----KPAHDVL-E-----------------------------L----------DAPV-PIVGGSFLPDADDLWDIMYKK-----E-VN--EVDYLL---GTTDGEFSYGLLG--------------------------------------TVPEVTADGL--NRTVLSAILP-------------------------------------------------------------------AQLNF-----------------------PVIDQ------------YMNPDS--------------------------DDPIYTRDRFIQLMT---DNRFTATTVLM-AQAVAA----------------------HD--TARV-YQYEFQ--H-HTTSVSP---ERP--------SY---AK-ADHG--D-----------------------DLFYMFGIPLLRDDTG------------------------------NS------WKYSFTQEER-DLS------------------------------LDMMA-YWVNFA--ANGD-PSDSTGAA-------RMRNLVTWPRFMTSSQS-YLKLDVT-SSAD---VKL----RESNMKFWNE---EVPRL-MG-KQVTTGG---AEKYTWSFLL-------------V--------AGAFSAVVS-------LL---Q-----------------------------------------------------------------------     =====>
brafl-c3xx27   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYTFKGIPYAAPPVGD-LRWR-----PPQDPA--G---WT-GVR-DAAQ----FGAR---CPQIVDA-KAP-------P-DSPLYE-VL-TYRSNSSSEDC--LFLNVYTPNVAS----TADLP---VMVWIHGAAMV------------------------IGAADT------YPAE-IPTSLHNVV-MVTINYRLGNLGFLPTRGA-------ETDSNVGLIDMVKALQWVQGNIRNFGGDPDR----------------------VTIFGQSGGAWAVSLLVMSPM-A----TGL--FHRAISQSGVAGLTT-----TRRGDVTRTENL-------------AARV-----NCTT--------NS-----YDDMMSCLRS----KPAQDLL-F-----------------------------L----------E-II-PIVGGRFLPD--DLWDLMYKK-----Q-VN--KVDYLL---GTNNDDYGM-LLS--------------------------------------VIPHFSEDGL--NRTILETILP-------------------------------------------------------------------APLQFDAD-QFP--------------V--TIDQ------------YLDPNM--------------------------DDPIYTRDRFIQMMT---DCRYAALTVLM-AKAVAA-----------------------Y--DTRV-YQYEFQ--H-RT-SLFS---MRP--------SY---TK-AAHG--D-----------------------ELFYMFGIPLLRDDTG------------------------------AS------WKYSFTQEER-DLS------------------------------LDMMA-YWVNFA--TNGD----STGAV-------RIRDLVTWPRYT-SSQS-YLKLDVT-SSAD---VRL----RESNMKFWNE---EVPR--------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xx28   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-GRRAGKTSG-----------VGDV----------------VVL-------AA--------------------------LLGLAGGV----VVPTTYGDVNG--------AELPTS-FIG---GAV-FDRIYTFKGIPYAAPPVGD-LRWR-----PPQDPV--V---WT-GVR-DAAQ----FGAR---CPQVADI-QAP-------P-GSPLNE-LV-TYRSNSSSEDC--LFLNVYTPNVSS----AADLP---VMLWLHGGGMG------------------------LGTADT------YPAE-IPTSLNNVV-MVTINYRLGNLGFLPTRDA-------ETDGNVGLMDMAKALQWVQANIRNFGGDPDR----------------------VTIFGQSGGAWGVSLLVMSPE-T----RGL--YRRAISQSGVAGIPT-----SRRGDTTKTETL-------------ATSL-----NCTT--------TS-----FDDMMSCLRS----KPALDLL-T-----------------------------Y----------DPTV-PIVGGRFLPD--GLWDLMYKK-----Q-VN--EVDYLL---GTNNDDYGYGLLA--------------------------------------AVPQVTADGL--DRTVFEEILP-------------------------------------------------------------------AQLKYVAD-QFP--------------VSPTIDQ------------YMNPDS--------------------------DDPIYTREQFIELMT---DSWFTAPTVLM-AQAVAA----------------------HG--DSRV-YQYEFQ--H-RT-SVFS---ERP--------SY---TK-ADHG--D-----------------------ELHYMFGIPLLRDDTG------------------------------AS------WKYNFTQEER-DLS------------------------------LDMMA-YWVNFA--TNGD----STGAA-------RMRDLVTWPRYMTSSQS-YLKLDVT-SSAD---AGL----RESNMKFWNE---EVPR--------------------------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xx29   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVWLHGGGLI------------------------GGSGDT------YPAE-IPTAFHNVV-MVTVNYRLSNLGFMPTLDD-------DSPGNFGLVDVMKSLEWVQGNIRNFGGDPDR----------------------VTIFGESGGAWAVSLLVMSPM-A----TGL--FHRAISQSGVAGVQ-------------------------------------------------------------------------------------------------------------------------------IVVGGSFLPE--SPWDMMHKK-----Q-VN--KVDYLL---GTNNDEFGFCMPT--------------------------------------LSESTS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSS--K-THTSYFT---TRP--------AR---VR-ADHA--D-----------------------DLWYLFGVPLMRDE-N------------------------------AA------WKYNFSEEER-ELS------------------------------LDMMA-YWVNFA--ANG-------GAA-------RMRDLAKWPRHTPSGQE-YLRLNVT-SSAD---VRL----RESRMKFWNE---EVPRL-MG-KKIRTAR---PDEL-------------------------------------------------------------------------------------------------------------------------     =====>
brafl-c3xx30   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGASRAESTFLRDTIRDTM-GRRAGKTSG-----------VGDV----------------VVL-------AA--------------------------LLGLAGGV----VVPTTYGDVNG--------VELPTS-FIG---GAV-FDRIYTFKGIPYAAPPVGD-LRWR-----PPQDPV--G---WT-GVR-DAAQ----FGAR---CPQVVEM-PFP-------P-GSPLYE-LSGPFRSNSSSEDC--LFLNVYTPNVAS----TANLP---VMVWLHGGGLA------------------------MGSADT------YPAE-IPTSLNNVV-MVTINYRLGNLGFLPTRDA-------DTDGNVALMDMAKALQWVQDNIRNFGGDPDR----------------------VTIFGQSGGAWGVSLLVMSPE-T----RGL--YRRAISQSGVAGLGA-----SRRGDTTKTETL-------------AASV-----NCTT--------DS-----FDDMMSCLRS----KPAQDML-E-----------------------------L----------DVPV-PIS-TVFIPF--LIQDLVYKK-----Q-VN--EVDYLL---GTTDGEFSNGLLG--------------------------------------I