Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....790..5....800..5....810..5....820..5....830..5....840..5....850..5....860..5....870..5....880..5....890..5....900..5....910..5....920..5....930..5....940..5....950..5....960..5....970..5....980..5....990..5....1000.5....1010.5....1020.5....1030.5....1040.5....1050.5....1060.5....1070.5....1080.5....1090.5....1100.5....1110.5....1120.5....1130.5....1140.5....1150.5....1160.5....1170.5....1180.5....1190.5....1200.5....1210.5....1220.5....1230.5....1240.5....1250.5....1260.5....1270.5....1280.5....1290.5....1300.5....1310.5....1320.5....1330.5....1340.5....1350.5....1360.5....1370.5....1380.5....1390.5....1400.5....1410.5....1420.5....1430.5....1440.5....1450.5....1460.5....1470.5....1480.5....1490.5....1500.5....1510.5....1520.5....1530.5....1540.5....1550.5....1560.5....1570.5....1580.5....1590.5....1600.5....1610.5....1620.5....1630.5....1640.5....1650.5....1660.5....1670.5....1680.5....1690.5....1700.5....1710.5....1720.5....1730.5....1740.5....1750.5....1760.5....1770.5....1780.5....1790.5....1800.5....1810.5....1820.5....1830.5....1840.5....1850.5....1860.5....1870.5....1880.5....1890.5....1900.5....1910.5....1920.5....1930.5....1940.5....1950.5....1960.5....1970.5....1980.5....1990.5....2000.5....2010.5....2020.5....2030.5....2040.5....2050.5....2060.5....2070.5....2080.5....2090.5....2100.5....2110.5....2120.5....2130.5....2140.5....2150.5....2160.5....2170.5....2180.5....2190.5....2200.5....2210.5....2220.5....2230.5....2240.5....2250.5....
9alve-c5khp2   	----------------------------------------------------------------------------------------------------------------------------------------------MVVREDTSLQ------------Q---------------------PIIQDVEIFLGIRYAEPPLREL--RFRAPRPYT-SQ--NWT------------ATRPMVT--PGEKCFQI------------SGS---------I------LTDTGSTAGHEDCLFLN---VYRPSAAE-------------------------------------------------------IVHLPVMFWIYGGGYV-DGDA---S-SFN--GTALAA-----LHNVIVVTVNYRLGHIGFLGSQSSLSE--E-----------------------G-TTGNW---------------GTLDTQ-------------------------LGLKWVQQNIEAFGGDKN--RVLL---FGESAGA---------------F-SVMW-HIAAPG--S-KG--------LFHAAIVQ-SGT-ASTPMFF---QTRTD-----AFRYYDW-----VASELAGCKDA------------ND--LACLREV---DFHNFTIP----NGI-RFDPARAPPWG-------------------------------------SPLFPAMPVGPI-----------I-----DGTA--LPDN------------------------------------------------------------P--LRMVENGL--HNDVPVILGVNKNEGSMFGLML-PKLIP-GL------NMPLAEDGVRKAIYHFVQNE-----TAVEELLELY------------------------------------------------------------HFER---YSSVFGSANG-----PF-------------------------------------------------------------------------------------EQVFYLIRDIMFHCSARRLADALVDK---------GKS-PIWMYSFDMPNLFG---SWAMPSPV--C------GLTWQPMEVRRV----------------------------H-------NNTAQGYP------MG---------VSHPGCLTL-------------------------------------------------LHL-------------------------------------------------------------------------------------------------------------------------------------------------------------FPCKFDK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9alve-c5khu3   	-----------------------------------------------------------------MKLNRL----------------------------------------------FPLILLSTSVGFQPVQISNGPI-SGMVVREDTSLQ------------Q---------------------PIVQDVEIFFGIRYAEPPLREL--RFRAPRPYT-SK--NWT------------ATRPMVT--PGEKCFQV------------SDS---------S------LTDTGSTAGHEDCLFLN---VYRPSTVEN-----------------------------------------------------GTSRLPVMFWIYGGGYV-FGDA---L-SYN--GTALAA-----LHNVIVVTVNYRLGHIGFLGSQRSLSE--E-----------------------G-TTGNW---------------GTLDTQ-------------------------LGLKWVQQNIEAFGGDKN--RVLL---FGESAGA---------------F-SVMW-HIAAPG--S-KG--------LFHAAIVQ-SGT-ASTPMFF---QTRTD-----AFRYYDW-----VASELAGCKDA------------ND--LACLREV---DLHNFTIP----NGI-RFDPARAPPWG-------------------------------------SPLFPAMPVGPI-----------I-----DGTA--LPDN------------------------------------------------------------P--LRMVENGQ--HNDVPVILGVNRNEGSVFGLML-PNLIP-GL------NVPLVEDGVRKAIYHFLQNE-----TAVEELSESY------------------------------------------------------------PLGR---YSSVYGSANG-----PF-------------------------------------------------------------------------------------EQIFYLIRDAIFHCSARQFANALVDK---------GKS-PTWMYSFDMPNLFG---SWSEFKLG--AFFSAYGNLTLEEMGTFHS----------------------------AEV--PFIFKQFRNVP------VN---------FSSFGISSI-------------------------------------------------LSLYMAH--------------------------------------------------------------------------------------------------------------------------------P------P--RQRGDS--FHNISDAFSCMWSH--MAADGSPTGPQQHCPGL-PDGSIPSWLSYSSILNGSEAQGIYMSIG------DEM--V-----MKPWRSN------------------------------------N-----------QYPDNE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9alve-c5l6e8   	------------------------------MRFF-AELCA----AVIALIFSGC-S----SSSTTTI-TPAPPTTIPSSND----------SA------------------------SKTATTTSPLSKGEVAISNGPI-SGINIAKNTTKQ------------Q---------------------PIVQDVEVFYGIPFAKSPVGDL--RFRAPQQFD--E--HWT------------TVKKMDT--KQSQCPDK------------YG------------------------RGDEDCLYLN---VWRPANATL------------------------------------------------------GSKLPVMAWIFGGGFV-DGNAAS-S-DYD--GSALAS-----QHNVVVVTMNYRLGDLGYFASPASFNE--E-----------------------G-TTGNW---------------GQLDQQ-------------------------LALKWIQKNIEAFGGDKD--RVLL---FGESAGA---------------F-SVVW-HIAAPS--S-AG--------LFHSAVLE-SST-SHTDIFF---QQPQD-----AYRYYDW-----VAKELVGCKDA------------ND--MDCLRHV---DASKFTLP----KNV-RFDPNQCPEWG-------------------------------------SPIFPMMPVGPC-----------I-----DGKI--LPDV------------------------------------------------------------P--LNMVKKGD--FNKVPTIVGTNRDEGTAFVAGL-SGVVP-GV------PRQPDMDDVRTLLFYMLQSE-----EAVDEALAAY------------------------------------------------------------PVAD---YTTTYGTESQ-----GF-------------------------------------------------------------------------------------ELASEMIRDAIFHCPSQELAQAISDN---------GG--DAYMYLFNMDPIFP---KWVDKINTGNRPMFGFGNFTPEQMGTFHS----------------------------SEI--PFVFKRFEDHG------VT---------VKEPN---M-------------------------------------------------YEVYMGH--------------------------------------------------------------------------------------------------------------------------------P------P--RQPGDV--YHQVSDKMSCMWAS--MAASGKPVGGDVVCPPQ-P--HLPNWGTYMA--NSKNSLGQYLHLG------RDV--Q-----MEPLVKD------------------------------------N-----------AYPHSEFASKDVCEFWNAQQFRFHDLRSDLTNTTTA--------DEKRV-------------------------------IMV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9alve-c5lxl2   	------------------------------------------------------------------------------------------------------------------------------------------M-VGVMVHSDLSRQ------------Q---------------------PIIQDVEVFYGIPFAEPPIGDL--RFRAPHKLN--E--TWT------------STRLMDT--KKSHCLDK------------MG------------------------TGAEDCLYLN---VFRPANTTP------------------------------------------------------SSNLPVMAWIFGGGFV-DGDAAD-P-RYD--GTALAS-----EHNVVVVTFNYRLGNFGYLASESSLEE--E-----------------------G-TTGNW---------------GQMDQQ-------------------------MALKWIQNNIGAFGGDKD--RVML---FGESAGA---------------F-SVVW-HIAAPS--S-AG--------LFHSAVLE-SST-SHTDIFF---QQPQD-----AYRYYNW-----VAKELVGCKDA------------ND--IECLRKA---DASKFILP----SDI-RFDAVKAPDWG-------------------------------------SPIFPMMPVGPC-----------I-----DGSI--LLDT------------------------------------------------------------P--LNVVKAGK--HNKVPTIVGVNRDEGTGFVAGM-SGVMP-NM------PKQPTMADVRTILFYVLQND-----TVVDEALERY------------------------------------------------------------ALNN---YDDVYGEVNQ-----GF-------------------------------------------------------------------------------------ELASEMIRDAVFHCPSRALAKALSEQ---------GG--DAYMYLFNMNPIFP---KWIKDINTGNKPLFGFGNFTPEQMGTFHS----------------------------SEI--PFVFKRFEQRS------MS---------LLDID---M-------------------------------------------------YQAYMGH--------------------------------------------------------------------------------------------------------------------------------P------P--RVPGDS--YHQVSDQISCMWAN--MAYSGMPVGGQAVCPSN-P--QLPEWGPYMA--NASSPLGQYLHLG------RSA--A-----MMPVKQT------------------------------------A-----------YYPVSEFVSAEKCEFWDAHNFVFHNLRADLSEPSTS--------TIIV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9alve-c5lxl3   	--------------------------------------------------MSGC-S----ESEDSETVTTVQPSGEETTQA----------PQ------------------------STSSPTSAIPNSGDVITQNGPI-IGTVIYSDMEKQ------------Q---------------------PIRQDVEVFYGIPFAEPPVGDL--RFKAPREFR--E--TWE------------EPINMTT--KKSMCVQS------------NG------------------------RGDEDCLYLN---VYRPANVTQ------------------------------------------------------SSRLPVMAWIYGGGYV-NGNS---L-SYD--GTVLAA-----EHNSIVVTMNYRLGPLGFLGSSASFEE--E-----------------------G-TTGNW---------------GQLDQQ-------------------------QGLRWIQKNIAAFGGDED--RVMI---FGESAGA---------------F-SVMW-HLAAPG--S-AG--------LFHAAILE-SGT-SHTGAFF---QHTED-----AYKYYDW-----LAQEVLGCKDG------------ND--MECLRAA---DATKFTLP----EGI-RFDPAAAPEWA-------------------------------------SPIFPVMPVGPV-----------I-----DGVA--LPDV------------------------------------------------------------P--LEVVRAGK--HNKVPTIAGVNHDEGTGFVLTL-KALVP-NV------PLLPTEESVEDTIYYVLQDE-----NAVQEAMGLY------------------------------------------------------------HPDN---FALLYGEENL-----GF-------------------------------------------------------------------------------------ELASQMIRDAIFHCPTMALAKALSDQ---------GG--DSYVYGFDMNPLFP---KRVGNINTGNIPGMSFGNFSVTQIGTFHS----------------------------AEI--PFVFKSFTDKP------VS---------VKNPD---M-------------------------------------------------YDLYMGH--------------------------------------------------------------------------------------------------------------------------------P------P--RSRGDA--YHNVSDQFSCMWAN--MAESASPVDGDAVCPAE-P--SLTRWGKYME--SDESPLGQYLHIG------KDSI-E-----MRKIRED------------------------------------N-----------QYPDSEFPSTEICAFWDTHPIVFHNLRSDLTTTSTF--------VQV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9basi-f4r451   	------------------------------------------------------------------------------------------------------------------------------MSTLLVETTYGPI-LGFQDTFPLQDK------------S---------SFTQPC--HGQGGGHDPVLKWLGIPYGQA----K--RWKKPVAP---A--SWS------------EPLMCTE--FGPYFPQA------------FDLLDQIYQGKSG----YFSRTAHLPCEEENGFNLN---VFAPSGTQP------------------------------------------------------GDNLAVMVWIHGGSLE-SGPSSS-L-LYD--PTEWIRSQGKSG--CIVVTGNYRTNILGFLACQDLAEEDEG-----------------------G-LAGNY---------------GAYDCI-------------------------SILEWVQGNIRSFGGDPD--NVTI---FGESAGG---------------F-LVGA-LLVT----Q-KK--------LFKRAIMQ-SGF-PGSLKHLE--LDSGS-----GHAVYRALLEKHP--------T-LS-----ELRSTER--LEFLRNI---PQDELVSF----------MAAR--------------------------------------------GSVIKEYGIT-----------IETSLNAASI--WTKP------------------------------------------------------------T--IELIKEGKWNPYLETVLLGTTKDEGSLFACLFN-ASKGIGL----------------EFLLNTLAPW-----CPRKTIDELY------------------------------------------------------------PNNE--------------------------------------------------------------------------------------------------LETDWINCTGSRLVTEQIFESPLEEVASAFNTSK----NLQTDELCKAYRYRLDAS------------------------IEDSRGWGCFHT----------------------------VDV--PLAFNIKSMWR------P------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSS--ESKVANQIGKAWFE--FARTGSPAS---------------EWPQYTTV-G---SQVYIFREN------GECI-I-----------E------------------------------------N-----------LNSTRSQVEQKRIAYWIDKMPYLTSSRAM---------------KETKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9basi-f4rr11   	---------------------------------------------------------------------------------------------------------------------------MASEDEFLVHTSSGPV-VGFQDTHPLSDR------------S-----------TASCVANGQFGDQSPINKWLGIPYAQA----A--RWTRPTPP---T--SWQ------------EPLLCHE--FGPYFPQT------------SDPFLTVYLGKPG----YHPRTWR-EQSEEKGHNLN---VFLPDGVQP------------------------------------------------------GDNVPVLVWIYGGALL-YGNSSE-S-IYD--PTEWIRREAAEGRKFIVVTGNYRVNIFGFLSSSEMTAQDED-----------------------G-LSGNY---------------GEFAY-----------------------------MWVQDNIAKFGGNPD--NVTV---FGESAGG---------------V-IISN-LLLC----Q-KK--------LFKNAILE-SGF-PGTMLYQD--SK--A-----ADELYDDICTK-A----------LK-----TGSREER--LTALRSV---PVDELLKS----------APQN-----------------------------------------------VGSAGFS-----------VE--KSKKAI--WTSS------------------------------------------------------------S-VHQVLKEGKWNPYVKSVMLGVTEDEGSIFVLFTQ-AHLPDGY----------------DTLCHQMLPG-----VSREDLDKVY------------------------------------------------------------PPLFP----N----------------------------------------------------------------------------------------GTSGKTPDYTSVVGCQALSDRLFNAPLECCANIWSSTL----NSQSHEHLSIYMYKLNAT-VHK--------------------IEDGRGLGAFHS----------------------------VDI--PFVFNIKDAWS------E------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSS--NAKTSALIGKYWFN--FAKSGCPEP---------------TWPQYDS-AA---PFRMVFEDD------GGTT-V-----------E------------------------------------D-----------LA-GKSELEKGRQEFWSQLL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9basi-f4rr12   	---------------------------------------------------------------------------------------------------------------------------MSSNDKLLVNTNFGPV-VGFQDTHPLSDR------------S-----------TASSVASGQIGDQLPINKWLGIPYAQA----A--RWTRPTPP---N--SWQ------------EPLLCHE--FGPHFPQLRFPQEPLSQQ--PVSVEVIYLGKPG----LHPRAWR-EQSEEKGHNLN---VFLPDEVQT------------------------------------------------------GDKVPVMVWIYGGALL-NGSACV-S-MYD--PTEWIRREAAEGRKFIVVTGNYRVNLFGFLSSSELAAQDED-----------------------G-LSGNY---------------GAYDCI-------------------------SYLQWVQDNIAKFGGDPD--NVTA---FGESAGG---------------V-VVSN-LLLC----Q-KK--------LFKNAILQ-SGT-PGTIPYVE--PK--L-----ADTFYEELCDK-A----------LK-----TTPQAER--LAALRSL---PADELLKY----------SPQG-----------------------------------------------AGTVGFS-----------TE--QSNKGI--WTSA------------------------------------------------------------S-GNDALKEGKWSPYLKSVLLGTTKDEGSIFAMLFQ-GVSKDGY----------------DLMCERMYSK-----VPRAHLDKLY------------------------------------------------------------PPVFP----D----------------------------------------------------------------------------------------IKSGESPDYASSVACQLLSDQIFIAPTENCAKILSSTP----NAQTGERLSVYMYKLNAT-VDK--------------------IEDGRGLGAFHS----------------------------VDV--PFIFNIKGAWS------E------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DST--NAKTSALMGKYWYT--FAKSGCPES---------------TWPQYDI-AA---PFRTVFEVD------GGTS-V-----------E------------------------------------D-----------MA-GKSELEKARHEFWNQIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9basi-f4rr14   	---------------------------------------------------------------------------------------------------------------------------MSSNDKLLVHTSFGPV-VGFQDTHPLSDR------------S-----------TASSVASGQIGDQLPINKWLGIPYAQA----A--RWKRPTPP---K--AWK------------EPLPCHE--FGPYFPQQ------------PDPAMLLYLGKAG----LHPRAWR-EQSEEKGHNLN---VFLPDGVQA------------------------------------------------------GDKVPVLVWIHGGALL-YGSACL-S-LYD--PTEWIRREAAEGQKFIVVTGNYRLNLFGFLSSSELAAQDED-----------------------G-LSGNY---------------GAYDCI-------------------------SYLQWVQDNIAKFGGDPD--NVTA---FGESAGG---------------A-MISN-LLLC----Q-KK--------LFKNAILQ-SGT-PGTMPNKD--PK--S-----ADAFYEELCDK-A----------LK-----TTSKAER--LAALRSL---PADELLQY----------TPQT-----------------------------------------------LGTLGIS-----------VE--QSSKGI--WTTA------------------------------------------------------------S-SNDALKEGKWSPYVKSVMLGVTKDEGSMFVMLLQ-ATSKGGY----------------DFMCERMYSK-----IPREHLDKLY------------------------------------------------------------PPVFP----D----------------------------------------------------------------------------------------SKSGGTSDYTSSVACQLISDQAFNAPTENCANILSSTP----NAQTGERLSVYMYKLSAT-VDK--------------------IEDGRGLGAFHS----------------------------VDI--PFIFNIKGAWS------E------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DST--NAKTSALMGKYWYT--FAKSGCPES---------------TWPQYDI-AA---PFRTVFEVD------GGTS-V-----------E------------------------------------D-----------MA-GKSELEKARHAFWNQIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9cnid-b7zf08   	-GKCKAM-----KGEETERSDIITQPLKTKVTKKRFKKIALAV-GIVFLSVA------AISIIFLRDH------VNI--TATR------------I-LSEN-HKPHSLDRHHENDV------INNGDDDVIVKTAAGVF-KGFKEMN----------------------------------------NEKVSYRFKGIPFAEPPVGQL--RWQPPVPK-----KKLS------------DIYIANI--SNTLCIQYNPPPFP----------------------------PVEREPSEDCLYLH---IHTPTLD-------------------------------------------------------EKANLPVFVWIHGGFLL-NVYSDVPG-YYP-DG-DFAS-----EMNVVAVSLSYRLNAFGWLSLEELWQEG--------------------------VSYRNY---------------GLMDQI-------------------------PGLKWGERKIRDFRGNPH--LVAV---PGESSGG---------------T-SIFT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9cnid-b7zf10   	--------------RST--------------KLS-KKMKVKLQ-RKLLLFTILCVH---ITSTFAVP----------QNRIPD---------------------------------AD--------RDYVNIDTECGPV-EGKRFTE--NVK----------------------------WHN----DSVNVYEFRNIPYAKPPVGKL--RWRPPVRLSDDPAQCWD------------GVLKYNK--NVVACKQDHPF-------------------------------TPSVNTSEDCLVLT---VRTPNL-------------------------------------------------------DPSSKLPVIVWIHGGGML-WGYNEMFA--F-HPDTEFSA-----YMEAVTVSINYRLNVFGFMSLKELWIENGP-----------------------NKSYGNY---------------GILDQI-------------------------ETLKWVKSNIKQFGGDSE--NVMI---YGESGGG---------------T-GVYC-LLCSPL--A-NG--------LFQKASPQ-SGA-PNIRTTH----EVAD-------------MKYRSIIDKADCQK--E---------SPDNIVECLQNI---DADDFLSL---FKGT-SV------------TPY---------H--W----------------KM-PTNEPYNGYPVE---------IL-----DPVV--VTK---------------------------S------------------------------------PDQI--PVHQNTQVELLIGNCAQETGPFPHKPKPDA-NI--------T----TWADLQAALE----P-----QMDTFKKGHYPHFLDQYQNDLKSPPQ---------------------------------------------------------------------N-------------------------------------------------------------------------------ITPKYVYEVMTSDALVLCTTNYVAD----------HLSKVKGYTVSRYVMSQPPTKE--------------IGL-------GLETAYHGW----------------------------DS--VLLFGLKFYKR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9cryt-b6a9b9   	---------------MN-------------LLNM-TPMIV----GIIYIMVILG-A----KV-----------------------------------------------------------------------ISCMEI-EGVQLIG-----------------H---------------------KKANGVTSYFNIRYARA----S--RFQPPQLLN-IT--EAVSIDSGYTTKFPQVYDVSEN--RGSSCPQN------------CADIQQTLNDTFL------CKGTEEQTQSEACLTLN---IFTQMPPLDM-LNQVSIMAKQVSAAASVSS------ASTLS---QNSSLS--RSITSLLQQNNSTLRPVYVFLHGGLYL-FGSSNS-D-INV--GDKLAE------SGAVIVTVNYRLGIFGWLKY--------K-----------------------NIARGNM---------------SFLDQR-------------------------VALQWVQKYISYFGGNPD--KVVL---AGHSAGA---------------K-AVLC-HATSPE--S-TP--------YFSGIILH-SGA-LTQHEISV--EEAEA-----MGEIAEQVAITKCPATILSCNTA----------------------------QLLEIQ----KEV-RSQL----IKN-------------------------------------DVSKSLHSWSPV-----------I-----DGYI--IQES------------------------------------------------------------C-SKRAREGKI--PDDISVVLSTTNMEGVQFFRSFT-SYLPSF-------FRSLATSSVALRYLLSRIFG-----SRAGDALRIY------------------------------------------------------------TNQSVRTLNLD------------EAMFSNITEDNST---------------------AEAKGF----------PSPTSSSSSGFNLFGNSRDGSSRDEKVTNILEDPVTLAYSRLLGDFIYSCPVRLLLKRLSRK---------NN--NIYAYFTS---EGF---KWAENLKK-----------------PYDD----------------------------VST--SFLSGKFG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9euka-e9c904   	---------------------------------M-LRLGN----RVASAA--LA-----------------------AATV----------L-------------------------LAIATIAHADGTVVIQTKSGPV-KGNVHS-------------------------------------------NGVTSFHGIPFAEPPLGEL--RFASPLALQ--R--NWT------------DPIDCTSNTTTLMCPQIRLD-------------------------------IFDIMGQEDCLYLD---IYMPPGAQAS-----------------------------------------------------ATQLPVMFWIYGGGYA-FGDKFELG-LYN--GINMSY-----NNNVIIVAANYRVNVFGFLANSILQATDPQ-----------------------H-STGNF---------------GLLDQR-------------------------LALQWTRANIANFNGNKD--QITI---FGESAGA---------------F-SVCF-HLASPA--S-RG--------LFASAIME-SGT-CSNTFFFQTLDFAES-----FGEI---------YTATFGCNAT-------QQTAAEY--LKCLRTT---PATDIMTG---LL------SWFGPDWP--------------NHINFPPTSFEGANQAPRALGILPTLAPIFPWGPV-----------M-----DGSDNGLPDL------------------------------------------------------------P--LSMMTRGD--FAKVPLIIGTNANEGVIFVPFAP-I-------IEHGVPFPLTDAGFQEIML-HFFNE-----TTADQAEAMY------------------------------------------------------------PKSDYTSND----------------------------------------------------------------------------------------------------QRATRILTDFFFSCDARRIARTFSDY---------NV--SVHLYQYVYK-DN---------------------FIDGWLLGDYHA----------------------------SEL--YFVWD--NQVP------AD---------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKFNAK--DSQMASTFGTYWTN--MPKVGSPNAKWNNAT------YNPDWPAFTR------ANDIHLALD------VPPS-T----------------------------------------------------------------GTQLLQQKCDFWDTVQGFSVAH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9euka-e9cba6   	--------------------------------MM-ASMRS----TAATRL-MLV-----------------------STVM----------LL------------------------AAAGLASAADPTLVLQTNNGPV-KGNVHA-------------------------------------------NGVVTFHDIPFAEPPVGEL--RFASPLALQ--H--TWT------------DPIDCTSNTSLKMCPQARLD-------------------------------YFQIVGTEDCLYLD---IYMPPNALNS-----------------------------------------------------STPLPVMFWIYGGGYM-FGDKFELG-LYN--GINLAL-----NNNAIIVAANYRVNVFGFLASSILKETDAL-----------------------N-STGNF---------------GLLDQR-------------------------QALQWTRDNILHFNGNKN--QITI---FGESAGA---------------F-SVCF-HLTSPA--S-RG--------MFASAIME-SGT-CSSTFFFQTLDNALD-----FGAL---------YASTFGCNAT-------TQSAADF--LKCLRTT---KAEDLMAG---VL------SWFGPDWP--------------NHKNWPPTTTSDVPTEGFSATPLPAFAPVMPWGPV-----------M-----DGSFHALSDL------------------------------------------------------------P--LNLITRGD--FAKVPLITGTNANEGVVFVPLGP-L-------VDRGVTYPLTDAGFDSLMH-HLFND-----TTAALVETHY------------------------------------------------------------PRKDYLTND----------------------------------------------------------------------------------------------------GRATRALTDFFFTCDARRTARAFNDH---------NV--TVHLYQYIYK-DN---------------------FIDGKLLGDYHA----------------------------SEL--YFVWD--NQVP------AV---------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HDFNEK--DRLMAATFGTYWTN--MPKVGSPNASWNNAT------LNPTWPAYTR------SNDLHMALN------VPPA-T----------------------------------------------------------------GTNLLQQKCDFWDSVQGGTVVSSMP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9euka-f2tx67   	-------------------------------------MMRLVA-AVV---AVMCLALGVGGHTFVEGR------VAGQSTATG------------D-------------------Y------HPQPNVTLPCGALVIGE-RDAKN--------------------------------------------SSLVVFRGIPFAEPPVDKL--RFMPAAVKTC--PGSST------------SVLNATK--DPNTCYQS--APL------------------------------GPDHVSEDCLYLN---KKR--------------------------------------------------------------LKPIAFWIYGGSNV-GGSLD----AYP-GLDNLPR-----QEDLCVIAPNYRLTVFGFLASPALAEADPR------------------------GVSGNY---------------GITDLI-------------------------AALKWVQHNAAAFGCDPD--SVTL---YGQSSGG---------------T-NIMA-LLSSPP--A-KG--------LFHAAISL-S-P-SLNITQDLV---------------TTERSHAPLINSTKCHSEP-----------THAALAKCLRAL---PAKELMRA---VPRA----------WLAGTADL--RPGRDP------------------------RGLTSLVGLL-----------AV-----DGVT--IANS---------------------------------------------------------------LREALATPI-IDV-PLYLSTMRDEED-----VQP---N------------VTITLWTRDRFH----K-----YIRDTFA-AYPAGTE----------------------------------DLLLQL-------------------F--------------------GGPNF---------------------------------------------------------------------------VTAPQAYYDMGSVIGVNCAAISLGR----------VAAKAFASPVYVVEVDLP---P-VHP--------------V---ALT--ALALES----------------------------RY--PFHIWDWILAQRSWDFGKS--------------------------------------------------------------------------LGGRS-------------------------------------------------------------------------------------------------------------------------------------IDAGAR--DLQGSQLLRAAFLD----L-----IGDSTSTN--HTSP--ALKPFLPS------GGRSGGSDGHLGGGLNGGDAAGS-----TEQSS------------------------SSSSSSSSSSFVVNVLQ-----------ESGSSSKEAVWLAAA------DFRK------AMC--E-------------------------------------RLHAVGFDDRFYW-IN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9euka-f2u3q3   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNSGLSGS----------------------------RAQ--SDSQF--REWP------PL---------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HDFDEK--ERRMAETFGLYWSN--MARYGDPNHNLG--P------DQATWPAYTP------AYRSWASMT------VPVA-I----------------------------------------------------------------NTQLEKAKCDFWQSRYTKYYFDGM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9euka-f2u4u9   	--------------------------------------MMTKS-GVL--LLVLGAL------TAHASA--CASAGAGAGEVI-----------------------------------S--------DTTII-HTAAGDV-IGKNLE------------------------------------------DHDVTAFMGIPYAQMPAGRR--RFAPPVPKQP-----WK------------GVMQATE--YGDTCYTAGDVHFG----------------------------NSGLPTSEDCLHIN---VFVPP--------N------------------------T----------------T------TTSNKPVVVFIHGGGFI-MGASNFPVVSPR--PFKFLV-----ECDCVYVNFNYRLGPLGFIALEEMRQEH--------------------------GHAGVL---------------GLMDQQ-------------------------LALQWVQNNIRAFGGDPA--QVTV---MGESAGA---------------F-CLCF-HLVSPQ--S-AG--------LFQRVIMQ-SSM-CDMKFQSYE---EAV-------------DQGNRLAKHVGCGD-------------AGDRLACLRSL---PAEKIQRA---FNNK-RG---------------------------------------------L-LLHTGVRWFP-----------TV-----DGVV--IPD---------------------------Y------------------------------------PVSLMRQHKH-NKVDVIIGNNADEASLFLLIAYNVA-VFES------S----WRDLLPATFA----------QDQLGRV------------------------------------------------------------AALFPQEWSPFQ-----------------------------------------------------------------------------------------------------KMAALL-DNMSSCST-LRTAM---------ALASSPESHVFVYHYTFVPET-----------------LGW---PFDQLGAFHGS----------------------------EL--RYVFEGEPE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDA--EKHLSQTIQDLWYA--FARGSTHNLSS-------GE---VHWPRLDDQ------HPVYLDLH------NGNLSARSTKPIERWEDT--QHRLEDHEPLFVNESEP--------------SPFAFCPFFDTLLS-TEKKLMAPPADFEEAWDSFLVNVVLVKL----------I--K---------------------------------QHGRTVLAVLLTLAVIV-I-------------------------------------------SRRCYPT--P----LTTATRPPPSTSHEHAHTNGVATRH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9euka-f2up38   	-------------------------------------MSRLFA-WLALLGLVAAVAIGAQA--------------EEKTDATG------------QYYQDV-GRGVRL-------Y------SDDPIEFVIVDTKDGAL-RGTRV--------------------------------------------NNTDYFLGIPFAKPPVDDL--RWRAPQPV-----QRWS------------GVRDANL--YAPDCTSSKSNYI------------------------------YLGNTSEDCLYLN---VFRRSTD----------------------------------------------------Y--SKEKLPVMAWLYGGSWE-YGGSSFI--VYD-GA-AMAD-----IGNVIIVTINYRLGAFGYAAAPALQKEDKH------------------------NSTGNY---------------GTQDQR-------------------------AALQWIQDNIANFGGDPK--NVTL---FGQSAGG---------------A-STSN-HVVMPR--S-NG--------LFDKVVIE-SGP-PSAWTYKTL---------------NQSSSHFSRIASAVGCAAK-----------TSEEEVACMRGV---NTTEIWRH---QEN-------------------------DP------------------------SV--QIDWGP-----------TI-----DGVE--LTDA---------------------------------------------------------------TWKLWKEGKVNNVSAMMIGTVKDEGSLFVEHIKPKATE------------QDLQTWISTTFT----G-----NLSDTIRKLYSASQY----------------------------------D-----------------------------------------------TPF---------------------------------------------------------------------------LAASAILSDA----EMTCNARRASR----------EM-TNRGVPSFLYSFTHL---PFVVK--------------L---AEPGYGVMHSS----------------------------EV--PFVFRSRLLL-----------------------------------------------------------------------------------LGK------------------------------------------------------------------------------------------------------------------------------------------GEV--ELANK-VV-RYWTN--FAWSGDPNIGQDMKP----TPGAVPWPQFSPQ------Y-NT-----YLN--LN---------------------------------------------------MTITPQQ-----------NFTSNAKCDFWDKVYASGCSLSHLP------VPC--D-------------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
asptn-q0d143   	-----------------------------------------------------------------------------------------------------------------------------MPNTTQLHLPCGPV-KAALTD--------------------------------------------NLIHARGIPYATS----A--RFQPPQST---A--KWT------------SPLDCTA--RAPICPQL------------PSR-----LESVM------GPLTDGHPMDETCLVLS---ITAPAR--A-------------------------------------------------------QHAPVLVWLHGGAYI-SGGGDL-D-CYQ--GSDLAG------RGIVCVNVTYRLGVFGYLPI--------D-----------------------GVAPANL---------------GLLDQI-------------------------AALRWVQDNIAAVGGDPG--NVTL---AGQSAGA---------------D-SMVC-MLAAEG--T-RG--------LFHRVILL-SPP-LGELH-----GRAET-----RARLAE------KAET--------------------------LMTK---DPREMTIA----ELL-DLQKKLLLDP---------------------------------------VRGRLMLFAPT-----------F-----GAYP--LPSE------------------------------------------------------------D-AVESKIVEA--ARGVPVLIGWTAHDGRPFASMSG-P-L--------------------CSLYSMPFVG-----GL------------------------------------------------------------------------------------------LE-------------------------------------------------------------------------------------ALGTWYMTRRYFSLPSQRLHARLVQA---------GCAST--TCSFEWGAQNN-------------------------PLQACHT----------------------------IDI--PFVLGAPGAWE------------------KAPM-----------------------------------------------------LQG----------------------------------------------------------------------------------------------------------------------------------------------SDAEEV---LRLGEEMKNLWTR--FVHGDRLTGE-------------------------------HIAIG------KDFV-T----------------------------------------------------------------------SDDMFIE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
chagb-q2h862   	----------------------------------------------------MAGL---------------------QNDA-----------------------------------YS--------PSAPV-QTESGLV-SGRV-------------------------------------------LTNKTRAFLGVPYAAPPTGSL--RWRPPQPPIP-----WF------------GVRSATS--FGPSAFQFPPPANSIYY-------------------------GGETSFSEDCLYLN---IYTGPE---------------------------HEPTT----------------------TTTTTPRPVLVWFHFGAFQ-FGSASNP--IYS--GAHLAA-----AGGLTVVTVNYRLGRLGFLAHPALTAEAESL---KLSSS-PGNND-HGGTGGTGGTSGNY---------------GILDQI-------------------------AALQWVRRNIRAFGGDPAADAITI---GGGSAGG---------------A-SVHI-LRASPL--A-RG--------LFGKAVVE-SGP-GVAPVVAGGGGDDARGHVAAYTSLAAAETAGVELAAGLGAS-----------------SVEELRAL---PAAAIAGV---HLER-AS------------GRW--RADLWPA---A----------------RT-SLSIFDTACP-----------VV-----DGYV--LPE---------------------------S------------------------------------PLTALLEG-RAADVPLLAGNVGDEGSGMPFLG------SVA------E----YEEYVRKTFG----------ELAAEALQLYPA-----------------------------------------------------------------GN-----------------------------------------------------------------------------------------------EEEVRQATSQLLADQVFVWST-WSSAR---------LQAKTLKSSVWYFKFERAPPIPK----NA---------DLV---EKTRAGAFHCA----------------------------VV--PYAFGNLDAWEWD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WTDA--DKELSKSVSDALVR--FVKTGRPGGDQ-------ED-DDTFWPALGSG------ASLVKIWD------AESS------------------RLEAPG--------P------------------------------------RLTSVTAFWDKYYGIEGQVAV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
chlre-a8i446   	----------------------------------------------------------------------------------------------------------------------------------V-TVSLGKI-TGAHC-----------------------------------------ASGESVLSFKGIPFAEAPTGTR--RWAAPISKFP------------------TAGLDATN--YGYMCPQGAGETRLTPGLTRLSPH--------------HPSLRVLRTLSEDCLSLN---VWAPA--------N------------------------A----------------T------ATSKLPVRFYIHGGGFQ-QGKLTNSDDSYD--GCRGAS-----DGNVVMVTINYRLGILGFMALPELKDSA-A-----------------------NGTVGNW---------------GLLDQQ-------------------------LALKWVKDNIAAFGGDPN--KMAV---YGESAGA---------------Y-SLLL-HMVATG--S-KG--------LFSSAVSF-SGS-ADAM-AVDLL-PGR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
cocp7-c5p5s7   	---------------------------------------------------------------------------------------------------------------------------MHDRMDIVIQLPSGTI-SAAQKE--------------------------------------------NLVHARGVPYAHA----K--RFEPPQSI---A--PWE------------GVVDYTR--PSTICPQA------------PSR-----LDMVT------GPLAKGRVMDEDCTHLS---IAAPIG--G-------------------------------------------------------QNLPVMVFFHGGAYL-TGGGDL-D-CYQ--GLELAA------RGVVVVSVTYRLGIFGYLQI--------P-----------------------GIAPANL---------------GLLDQI-------------------------EALNWVKNNILSFGGDPS--NVTL---FGESAGA---------------D-SIFC-LMAAEG--T-EG--------LFHRAILQ-SAP-IGRRY-----DKSAE-----SLTLALS---KAAQEK--------------------------LQSL---AAGSPSIE----ELL-SIQLQLLITAK-------------------------------------KLGSRGMPFAPS-----------F-----GQHP--LPQI------------------------------------------------------------S-ELDDVIRKR--AKDIPVLIGCTKDEGTPFAAMND-R-A--------------------ARFFTIPLLG-----RC------------------------------------------------------------------------------------------IR-------------------------------------------------------------------------------------WLVSWLITKKVFHSPSKHFQKQVLAA---------GGKCS--SFYFRWAPPSS-------------------------PWGAAHT----------------------------IDL--PFLLGSWSSWE------------------DAPM-----------------------------------------------------LGG----------------------------------------------------------------------------------------------------------------------------------------------SKSRDV--VERVGSHVKDVWVA--FSKGVDLGSN-------------------------------TLIID------ESFR-S----------------------------------------------------------------------EHCIKEKKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
crypv-q5cre8   	---------------MK-------------KNYH-FKIIT----NLLLILFLYK-I----EV-----------------------------------------------------------------------FESVEI-EGIQLIG-----------------K----------------------KNNGITSFYNIRYGVA----N--RFQPPKLLS-IT--EAVIMDEDRTSKIPKSYDLSTN--KGSSCPQD------------CSDTQQTSQKTFL------CRGTEPETQSEACLTLS---VFTATNQIEEILSQFSTVAKHVSSNNTQINMLSSVNNTLMN---NLNKQK--STISSIVQANMSSLKPVYVFIHGGLYL-FGSSNS-E-TNF--GEKLAE------SGAVIVTINYRLGILGWLRT--------K-----------------------NLSSGNM---------------GFLDQR-------------------------IALEWIHKYIVNFGGDPN--RIIL---AGHSAGA---------------K-SVLC-HSVTEE--S-NK--------YFSGVIIH-SGA-LSQNETAL--KEAEN-----MGEMAEAIASEKCLATILSCTTK----------------------------QLLEIQ----KEV-RTQI----VRS-------------------------------------NPSKALHSWSPI-----------V-----DGVI--IKDS------------------------------------------------------------C-RNLALSGSI--PKNINVIISTTNSEGVQFFRSFI-AYLPAI-------SRGLATSNFAFRYLVSRVFG-----PKAGEAMKIY------------------------------------------------------------SNNNFANSASIASDYEISDPNYDLQNNTNINHDNSSYVNN---ETISNPIEIQKEDNETMIGFKADDIKYADKENNQIVSSSGFNLFQVGRN--RDEEKWNGIIDDPVALAYARMIGDFIYSVSFFI--KQYFIQ---------IN--PLFISVPS---KNV---H-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
ectsi-d7fs16   	-----------------------------------------------------------------MEW--LRKY-------------------------------------------P--------RTVDV-ETADGVV-RGSLLR--------------------------------------DREFQKVIAVFNGIPYARPPVGEL--RWQPPQPVEP-----WE------------GVKVTRR--YGPEAPQLGMEFMGFLRAAVQKHAFGTVQTKAYIHGARLLRTRLAAKQSEDCLYLNVRTVSPSVVGDLGAPPAPRRGDRDAGDSCPPSSGPEETPPTPTTQGTGVGAQSTAADGGGGAAAGAAARLPVLVYIHGGDYH-DGAGASRP-FYL--SNALPI-----KGDVVLVTFNYRLGLLGHFCHPDLSKEAEA--------------------AGRPAVSGNY---------------SILDQI-------------------------AVLRWVQRNIASFGGDPE--NVTI---MGSSAGG---------------E-SVLY-MMTSSL--A-RG--------LFHKAICQ-SPA-CTPNSLMHLREPFAC-----FRP--SEDNGVDFAFRLVGADR---------------GQVSRLRNA---PLRQIMNA---YYQD-GT-----------------------KR-----------------------PEPRQLFYP-----------VV-----DGHV--IPK---------------------------P------------------------------------PVESFLLGE-QAPVPLLIGNNADEGSLCYPVTYSRT-RVRD------A-----------LYP----------SP-VRE-AGREAYGDEGA--------------------------------------------AAL--ADLYDPAWRETGEGA---------------------------------------------------------------------------------------------EDGSPSDCDFFTDRVFGQKVHWLAS----------HHHRLLRRPTFVYVFAAAPPR-----------------------EGQTVGAFHGA----------------------------EV--PYAFGSRPWFI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGPE--DKRLASAMPDYWTA--FARGGDPNGTL-------RP--RVFWPSFDSE------PGKGRLIV------LGHA--IEAKKMDRLERY---AILHTHVRR-----------------------------------------VLADLESLRKWQAKREQHERRATELRAAARARAI--KNDQQQEE-------EREEDG-----------SAERGEGLAAE-------------------------------------------------------------------------------------ARVPFRQLQKQRSSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
ectsi-d8ldu4   	--------------------------------MA-IP-----------LLIHRSAA-------TID----AFEYFQSEQDY----------------------------------------------GRVAVDTELGRV-VGRVL-------------------------------------------RGGVRGFLGIPYALPPLEKL--RFEPPVPLAS-----WG-----------SERLEALE--FGAECMQSIEGNPIS----------------------------------------------SAS----------------------------------------------------------PSSLPR-----------------------------------------------------SLCTR-------------------------------RSPAVCF---------------GRLDQR-------------------------LGLEWVHDNVASFGGDPG--RVTL---FGESAGA---------------M-SIGQ-HLHMDG--A-GV--------LFQQVVMQ-SNP-MGYRFRSVT----------------VANFLGEAMKRGLDCFS-----------------LDCLQTE---PASEVMRV---QESI-MG---------------------------L----------------PR-SVGDFFTWGP-----------VI-----TDRN--YRRH--------VGKHRKTWNCDTYEEEAEERERQESRTVTLTGLALAAAAEHASAAKAPGGRGVMSRGRGRDEGQALPPVPVMLGVNSHEGLMFVHGAFPVT-MPKL------V----YYSFVTALFR----------TSVIGVLRAYGHLADQCE-----------------------------------------------------------------------------------------------------------------------------------------------------------ESGDYRRVMSQIMHDYLFRCPN-LRAAQLL-------QEQNGRDAPVFVYEFSHPTEVP-----------------GF---PECSGSSCHTA----------------------------EL--PYVFNNTSSSPGEEVAGAIGGGGAGLAGRVAADLTEMA---ADALAVSVAEGDEEGEGEGEG-GGDDHHGGNRGEE-QPAAATVTVEPHFSSGRGSRATAAKEEAEGSEALTGGESSGRANSEETLGVGGRRGGGDDADAAGHSETMAEAEGGPGAVRRRDIDTDNGSSVSRTSSGSVPGAGERGLGGSSCAAMAGGGGAGGSDDVEEARSEEGGGGDSAAPPKEPRRPSVHEAAEA--DMLVAEAMVTYWAS--FGKAGDPNSAN----------APVVWPAWEGR------RLTAQGNT--------------------------------------------------------------------------------------------------------------------------------------------------------AGAAAM--AA-------------------------------------------------------------LLA----SGHGGVGKGSFSDV-FADAWSQASPT------AAAGAGAGAAGGSWQGG--PYFLEIKARP--------------------------------ETREAQRDCMC-------EFWDRLKYRH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
helze-ORF145   	--------------------------------MA---NLLLVC-SLFVVLVKCCTC---------------CE----------------------------------------------------------YKTDAGCL-VGQDD------------------------------------------QVTNTVNFLGIPYGVG----R--RFNNAKLYRASPND-----------------TMHAD--TDIECIQ------------------------------------GDSLGTEHCLTLN---VYKPQG------------------------------------------------------TVAASRFRVVVVVHGRDYY-KSDAHSERHRY-----SHFT-----DADFIVVHVNYRLSVFGFLCIDR------------------------------DLAPSNV---------------GVHDVR-------------------------LAVQWVKRNIAAFNGDSE--SINL---LGYGYGA---------------V-IVHI-LAWKGLVVRTVT--------MFDSPLLY-NTD-SSLPYKTDS---------------------VSAINEQAVCTD------------------SVIRSA---RVLEFAKRLNLTNSTVAS-KRIERRLLLKLKRL--DARVLVRT--V----------------HRAETATLNLHGQ-----------TS-----DASV--LVQLDASGVQGNLSRNLPFSVCILNARD----------AL---------------------------DFDFFNVPFPATTVPVLIAFNGNDSRFDTLDGY--------------------WSNLYN-WR----L-----DS-KRSILNYTHS------------------------------------------------EVVVPLLIHYLNTWNNNKASTVKHQQ----ELIVSNT----ETFLFKR------------------------------------------------------------------------------SENQQCPDSSLD-----PE---CKHFHYYNNS--RFTLERVPVA-T----NET------VPFVS---IMTTVGGFNVSISEYFIDAKSVGVGSIINGYALPNVESGTL--KFKFNPLTLLQSDEPSVDVASVQRGAPHFE--PLPEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLSS--VPEVATTLHDGFTT--TIRDTFTTTATLP-----TLSNNPTRPSTTH--------NSTLPST------T-------------HKPTLPTSIFLK----------P-----IRKPNNGTT---SLIPIFPLKPTIKNQTAVHSPNPVE------------QYI----------I--D---------------------------------QQEQTLSSLTIIMIMIL-CT----------------------------FSALLFVLVCKFVVALVCISI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
hvave-este     	-------------------------------------MCKSRLPTVLSLTLIYISI----SIGFSVYFYVLMEAAYDQFS-----------SM------------------------FESYTQTAVHLQSNSRTLKSDL-SDYMQLLNYSRKFDESGEESVLRRHNITTPRVFYIDLNYTTALGAENRNLNMINFYAIPYRYVDLLDP---FGNSIPVTGRT--PAT------------EYIDCSRD-KKEKCIDS----------------------------------IPPFDGVLDCLSLD---IHMQPWSRN----------------------------------------------------NKSFNRPIIIWLGEV---------------A--GELWR----LVAGGLIVIRANYRRGCYGFLCHHDQ-----------------------------SLPYRNQ---------------GVNDVL-------------------------HAIDWTIENARHFAGDIS--KITL---AGHGASA---------------S-LVEY-IRLNHG--H-HL--------PLDKYIVM-SANNFGSRDLYC-SSNSNV-----MV----------TTARLLGMPPSPA-----TESGKERSVYESVRYLSFVEPKLVMSK---LYGL-KAAFHPCPLSV-------------------------------------N-NRRASTFGIG-----------FK----------TK-----------------------------------------------------------------NHTSSNCIRTANEQPVLFTNTLNEYHNFVYGST-------------------------------VFT-----HARSET-ILR------------------------------------------------------------T------IGD-----------------------------------------------MLSRHFIESRLAYANSSTEKLI--------QQ-VN--GQYNVVDGEFVDY--DAFIRLLTDFAFIMPTVKMNEFTTEC---------GG--NSYHYVFDFGN-------------------------------STHG----------------------------DDL--KMLTSSANDTS------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THF--QRQLADGLGFILSK--FVRRGYPVKKQD------------GWCPSTGLVA----QIMEMNTK------D