MSA from Cobalt (Ncbi)
Cobalt
Color code Main amino-acide (aa) at this position Non majority aa at this position 50% conservation Catalytic site Catalytic site in alignement
Position ....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....
9alte-a3j8q5 -------------------------------------------------M-----LLS--FTGLLVMSA--------PSLTQAQDEPAD----AVQT----RDDVAAADEAAEPNSNP--------------DDKAAQ----PADDRP------QRASVVTGQGTMALQQQWP------QSAVWLEVDGADGTPTSVLSLVFTPLKNAATIAVVVLADEGHNAG-EGFVTAFAGSLA-DRGLAALTLGLRAPAGGLKQVMER-ELPLPEASP-----AVSAADEAQAPQPVAAQVAGT---SSNANPD----------------------------------------------------------------------------P---DPMLIDV-MAGTELF-EAELQYRQEVAAQ-LRA--AVGY-LKREGYQKVVIVGVGRGANFATALP---ELAD-------------------SAGLVWLLPRFYPR------------DLNVLAERFTETP---RLRVLDVQAAL----GN------RSQSA-----MQRTTVM--NQVEVAQYQRQRVTVQEPV--QARQGDALASRLAAWIKADNKPDMD---------------------------------------------------------- =====>
9alte-a6f4s0 ---------------------------------------------------------------MKCLVLLAVVGALWAPQTLAQAQNDA----QDQS--------AGM---------I--------------GQDAET----TAGAAV------KRPLISTGLDSDAIARTWP------DSSVWLEPPEEEP----VLALFEPEAETPAKGALVILADEGQSPA-SGLAAALRQPMA-RAGWAVMVLGLEIPPHEVQQARRQRGLEAPEEA--------------GAPDKDA-----A---DETGDKP----------------------------------------------------------------------------G---ESVMIDV-MA-SDDVEALADQYRARIQKT-LTA--AVGN-LVGRGYSRVAMVGVGRAAGHVTRAATASGGQD-------------------VSALVWIAPEFSQS------------DSKALTESLGESG---ALRVLELYSAR----SSLGTGSTIQRSP-----KQREAAL--RRAGVADYSQQPVAMAEQP--QPREAPALTNRIAAWLASER--------------------------------------------------------------- =====>
9gamm-a0y2k5 -------------------------------------------------------------MAFSCVALL-------ALC------------------------TTA-----A-----------------------------EHIAPP----------SLSSIENSDIKRLLP-----TDEVKTMLAG---E--TEFLSLRSEYMSADFRGIVLLIPDWQSTPTNNAGMSYLRKELN-NLGYTTYAMTTPDIDWKASKIAE------PAAE----------TAPSAATET---------------------ES-Q-----------------------------ANSESE-------------------------------QPDASSKNEAPHHV-DAIEAISDEILDNYKLNLLAR-YKA--LYQT-AMQE-PTNIVVIAQGTSAGVLTEYYADFPQER-------------------IDAFISVSSYLPNA------K-----RNKSLSQTTS----LVTPALLDIYYAS----DNRD----ILINL-----KNRQRWV--NRNAKFDYRQRQLFGLRDQ---PQQHARLTKEIDGFLRRIF--------------------------------------------------------------- =====>
9gamm-a0y831 -----------------------------------------------------MTKTILTLLSLLCIPA---LSLA---QGTG------------------------------------------------QDTG----------------------------KESLFDQQVA-----EQEKVWLNV---GE--QQQLAFYLTESSGTAYGGVLLIPDIAKHPATLGSINTMRIALS-KHHWSTLALNMGGANEA-------------------------------------------------Q------------------------------------------------------------------------------------------------------------SLDL-I--AAGIQF-FNEKEIYNIAILGEGRGAAHAILYLASKPPTDA-----------NSAKTDRISALIMVDAHNSTSD-----------NEAHILQKLA----EVAIPVLDAFSNG----DYIE-----QRQA-----DKRKDTA--RETLNKTYHQVRLPQASG-EQ-QNGDNRVTKRIRGWLDKN-IANLTAPLI------------------------------------------------------ =====>
9gamm-a3wld1 ------------------------------------M---------------NIMRVAILLF-VICWS-------------------------------------------------------------------------------------------VISHGQDDRARFVP-----PDEIVWLKDATEKD--VQYLALQLEPLRSFERGQFVALPDWGLHPLQSSLIKSSYHEAS-KMGWRSWGLTPPSMLIQPTSLAH------HTPD----------S------------------------------------------------------------------------------------------------------------------EFTQ-PDDNALEPYRAALFKR-LEA--LNEK-VSQH-PGFVVWLVEGISGALWIDWINKNPSAA-------------------PDAVILLDVYLPQP------A-----LNRVLGTKIA----KLTFPVLDIKSAS----ANRW----VAKQW-----SMHETLS--QKYQQLSYRPRSLLTRPP-----EAANELKSVIQGWFKFHGF-------------------------------------------------------------- =====>
9gamm-a3y8k6 -----------------------------------------------------MR-PKNITHGLLIILF--ILPAI---AFSA-DEAEEESPQTSDL----------------TTEDAAQTDNTEAVQEKKTTTPR-E----VIPR-SF-----T---PSQQIRIQTLTEQ-I-SQRTPNEIETLES---QG--ETFLALYREAQGNDTQGCIILIHGNNEHPDWPRVIKPIRMSMT-QNSWCTLSIEVPDNMTKEAITVPTEP---ASEET---------------------------------------------------------------------------------------------------------------------------------TEGEIKLPNEESVFAR-IEA--SIAF-TSDKGVPNVSLLGYGTGASYAIKYSINNNLS--------------------SGALLLVSASMPNKM-----------SPFPIAQLLK----NSQQAVLDYYIRP----NKFD-----KQFA-----DARYLAMSQRENQVPLYTQIKASSNTQ-Y-DIN-SNQLIQRVRGFLKQN-TQQREQRKQLPSTQKALFYN------------------------------SPIESGN------ =====>
9gamm-a4bhu8 -----------------------------------------------------MRGQFALAACAVLTTV---FV-----TLSG----------------------------------------------------------ASALAAPI-----P---MPKLQQSLDIQQHYRNALR-GEEVIELST---DT--ERFIALSLQQRTATPQGGLLILHDVGHTPNWPFLLQQAREYLP-DVGWNTLAIDLPTPARDAVGVLPLDD---TDT------------------------------------------------------------------------------------------------------------------ASAQ------------TPQQTP----DERVLAR-IRA--GLAR-LNSLGDFNIVILGFGDGGYWGARYLAENLTEAE----------------QDGYGLILVEAPG-QY------------PD--LDGFIG----ELPIPMLDLYMTD----SDYA-----HRRA-----KERKASA--ARAENEDYQQIHDALRQS-TYGKPSIDRTTRRIWGWLREN-AAGGEAQLEEQTLY------------------------------------------------- =====>
9gamm-a4c9a3 -------------------------------------------------------------MLIW--SLN-------LFA------------------------AQA-----L-----------------------------EIKAPD----------SLESIFQQDQFHYYR-----GDEIKMVLAG---E--TEFATLFRDRTSAMAKGIVILMPDWQLPANNYYGLDSLRKTLN-QYGWVSYAMNIPDPIAFYQQEI------------------------------------------------------------------------------------------------------------------------------KADNTLFHA-PDAERLDSDALNAYQLQLMSR-FKA--VYQT-ALGH-PGFIIVIAQGATSTLLVDYFAKTPEEE-------------------VDALIFLSSYLPDR------A-----KNELLNQNFA----KVKPPVLDIFSTA----DSSL----VKETL-----SQRKIIA--TREHKLNYRQRELFNSQTS---PQQQARLTKEIYGFLTKSGL-------------------------------------------------------------- =====>
9gamm-a6f6d7 -----------------------------------------------------MFKALVLLLLV-------------SLSSQAIEQ-------SAVD----K-ESDK-----P-----------------------------TITFPI----------SQQRVFDQDLTKYSD-----SNEVAWLGDI---D--NRFLTLWREQTTGKVIGTSWIFADTYTSANNPNIIQTLRYQLS-DKGLHTYSVSPLSQPLKSEHA-------------------------------------------------------------------------------------------------------------------------------------------------------EQRLQAQ-LLT--LQDK-FASQ-SGKRLLILQGVNCQAIINILVNNPDIY-------------------VDAIVLLSAHSPTS------E-----LAKQFISQMH----QLNAPILDLYAQT----DSLA----VIDEA-----KKRHTAA--KRINKGNYRQIEMIGLPGQ---VETQIATSQMIYGWLVKLGWY------------------------------------------------------------- =====>
9gamm-a9d9k1 -------------------------------------------------MRFN-TALVIALFLLL-T----------APVAIAADPQDTSPNEAMA----------------------------------------------------------KENMIEDKAVFSEKYDYLP-----QEEVIEITLS---E--QQTQVLVRSWSGKKQLGTAILLANPGMTADGAGFQAYLRRKLN-PAGWATIAITPPKKIAMLNFTTS------AEEI----------A-KAGEMKG-----------NQQANEA--------------------------------------------------------------------------------------TEQYSDEVWQDIRDKQSLFISQT-MNQ--LDAI-GAPY-PGKRLLITSGQGAGLVIAMLSNNLLAK-------------------PDILVLINPYLKMK------H-----ENLALAKQLA----ELDIPVLDIQSFD----GHRA----SSATA-----HMRAELS--PQNSPYRYSQQTLALNLNN---PMSWESALKSIEGFALRISQGPRK---------------------------------------------------------- =====>
9gamm-c0n1v6 -----------------------------------------------------------------------------------------------------------------------------------------M--STFVTNGFA-----TDTE--SGTVAESTPQSMQAEAGHVEGYMTLPL---GD--EVFDATFVADKTGRDYGKVLILPDQDGSIDSYDLVHTLRVRLA-ESGWSTMTVALSYPYQPQLLLSPNAN---DEEPV-------A---QIE-----------------------------------------------------------TTSEA--------------------------EVGE--SAT-----------------------TSDDDNAGR-VAA--AVAY-LNAQQPGPTVIIAMGKSAELSATAIAQVGKD---------------------NALIWISPEWQAE--------------------TA----PEAQYVLDITLSA----SAYE------ET----TNVQQRAVM--MRKNVVQYSQRQIPGATS-NF-NGFEQPVFNLIRNWLYKAFAQGATS--------------------------------------------------------- =====>
9gamm-c6n3m2 -------------------------------------------------------------------------------M---------------------------------------------------------------------------------EVKFNGKNIKL---------PYWAAV-------------------KNPHGAVILIHG-APQAQWSMLLAHLAKKLA-INGWSAVLVNCSQDNPEP--------------------------------------------------------------------------------------------------------------------------------------------------W-----------VKE-LPE--VINT-LRQQKNNRIIVVHYGEQLKQTFDSFNKSPKAA-------------------IDGLILISAYDIPK----------------TDDKKP----ELSMPLMDIAGQF----DYPS----VMEQM-----SARENE---FAQ--NQYLALKIPGAHH-DY-EYSHQLLLSFMYGWMLKR-AEFKPTPPPVLVSYIESIEPLMPKQVALDEEGDWTGFVYNPEGQPTQEIETP----------- =====>
9gamm-d1kbt2 MLSRLILIMGLLFSQASLAL---PFGLPELPNFGDF------------DPNSLRR----------SFNE---FI-----GVEP--------------------D--------------------------------------F---------------DREDRMVGEIEESVM-----DGDVEFLPLSK--D--REVFSIFMEADADTPKGGVVLLHSRGYHANWSSTIKPLRVGLA-EKGWHTLSVQMPVLDKKAKYYD-----------------------------------------------------------------------------------------------------------------------------------------------YVP---IFPYAHER-IEA--AIDF-YKQRGVDNIILIGHGCGAHMSMSYIDKYGDSK-------------------ISAYVGVGMGATDYKQ----------KLIKPFP-LD----KMLTPVLDVFGEN----DFPG----VVRLS-----ESRQDLM--DVSANAKNAQMVIKGADHYYKENGSSQVLVKTIDTWLSGL-K-------------------------------------------------------------- =====>
9gamm-d1kde2 -----------------------------MFYNDNI------------KPEVVMK--LLLSFLLITNIA---FA-----QVVP--------------------D--------------------------------------Y---------------AKEARWAEQVEDTLM-----DGDVIWLNAN---S--HEFLAIYTPSESDAKQTA-VVVHGLGVHPDWGQVVQPLRVALT-EKGFNTLSIQMPVLENGVGSEG-----------------------------------------------------------------------------------------------------------------------------------------------YAP---LLVDADNR-INS--AVNY-LTAQGLEANVLIAHSLGSVMSTHYLANNANPF--------------------KRYVGIGMPKTT------------------AQYLS----NIDIPVLDLYGND----DIPP----VLNGT-----KLKAQ----QSKHNSNYTQIEV-GADHFFNDK--DDLLIDTISAWLK------------------------------------------------------------------ =====>
9gamm-e0hpu5 ------------------------------------------------------MARIISLLFCLLLGFT-------AISSRAADPATATP--TP----------------------------------------------------------------AEDSAKKLNNRYLP-----ENEVKQITID---N--QPYDLLVRPWEGKKKLGAAIILPATNGTADAPGLMAFVRRNIN-PAGWASLSLTPPTELPAANFATA------ATEV----------T-SPGAAQL-----------SSPSNKP--------------------------------------------------------------------------------------SPKIKPEDNSKHLQEQEDFLVQS-MSQ--LDAV-GADY-AGKRILITADQSAGLLISLLSQKKIAD-------------------PDVLIVINPYREDE------K-----LNQALAEQLA----KLTLPILDIQSPD----GHPA----SLETA-----ANRKILA--VTLKSPNYRQTSLALNLDN---ESAWQNCLNAIKGFSARMSGAQ------------------------------------------------------------ =====>
9gamm-e1ml50 -----------------------------------------------------MS--LRFIVFVLCLAG---GV-----CLAG--------------------D--------------------------------------E---------------KREADFADGINKTLT-----IGKAVWLEAE---G--RKFLGLYTETEKAAGKGVVIILHDMDGHPDQKQLIYDLRVFLP-EHNWTTLSLQMPLREVGVEKED-----------------------------------------------------------------------------------------------------------------------------------------------YYA---LFPEAAAR-IQS--GIGY-AKSNGAENIVVVGYGLGGLMGIYALSEQV-AD-------------------IKALVTISLPVPTTEN----------KTAQTLELIK----KIKMPMLDIYGAV----DVPD----VTESA-----RDRRL----AAKENTGYRQVKINDEGHAYLHD--EGLLVKRIYSWLGVT-VEAAPVAQ------------------------------------------------------- =====>
9gamm-e1vli3 MK--------PWW-----------------------------------------PTAVFLSITTLMWPESPAFGAP---QAAA-PEKQAAPEKNAPSKGQQEPTPQA--SAETPSSTPATPSNTEPTEPANTDTAPPA----PIRNPPL---------RLEIPRSKALAKQIKQWEGAEGDVLWLGE---ES--DPFLALSIPNYGGETQGSVLILPDLGQNPDWPGVLRKLRTQLP-KHGWTTLSISLPDLGPIIPDLLPLPP---PSIPT-PTAPSPVAAENADQQ----------TENPEPA-SAPENASATPETTDGKKGAAQKETAQKDAAPNQADAAPEKTKTAPV-KSEAVEEKAEATKGSPESAPENPEAASGNTDTSTAQPAPPPRQDFRQSGSEIDPKIYPEEVARR-IEIAAAAPT-DGDANPKHIVVIAFGKSAGLVAHIAKDLPIPT-------------------LAGIVLINPEPYPD------------ASFDFPQDVA----ALSAPVLDIVPQMLPASNPLL-----RKQA-----MGRAQAN--QNAPVKHYEMRVITGASR-HF-AGYEPFITKGVRQWMAQQ-TQNRPQMQQIPAAKPVPQNVPPPP--RPTPPPDPP---PTTQKLPAPDLNAPIVAPSAPQTKG =====>
9gamm-q1n3w0 -----------------------------------------------------MTLKTLLMILTLLASV---LV-----QSQE-DDSVPDTEQSTPSESQ-EPD---------------S--E---IDNASTQTSSEK--NSEVIERYL-----P---DTSEQKIREVIRHLDLYQR-TNEVVRFDE---GE--DSISGLYLPENTGEPQGGVLILHDIEQHANWPFVVAPLREYLP-DYGWNTLSLFFDDYIKERLPEIPRTE---PSTND-QSEEM-SETTGAETTQN-------SSENETNE-SATENTV----TEDSETGEDQNFVE-----------NPDDSEGIGLSDQDELAEIADR-------LDEIPNTVSTREEIEEA------------EPEQPREEVFIERMRET-VEG--GLRQ-LNTLGQFNLVVIANGKSANWAAEALKTRFAQAS----------------NKGYALVLINAQSSAY------------PDYDLNQSLA----ELKIPILDIYTYQ----TPEA-----KRAA-----RNRKSAI--VRNQNDKYIQIPLTVRDD-NT-FDRHNLITRRVRGWLKTN-AAGRTVGVKQKKDNG------------------------------------------------ =====>
9gamm-q2bk20 MC--------SYFNGA-----------------GVL------------LSACILPIIAYMNIRTLCLLIAYLFLTS---PVYA-EEAQNE-------------T----------------------VQPA-SSGAAPSMSEKPRTEPNP-----N---IARISDLLKIQDPIT-----EVLHLDTGK---DD--EKLLAFYRSEGSGIKQGGIILFPDTETHTDWPDGLSELRKGLS-DFGWYTLSIYLPSEKRPEIPERTLPV---LSSIK-PQAPP-SEAESAEAG----------EGAEEPQ---------T---------------------ENTATEAPASTEKT--------------------------ETQSSNN-----SDTSSE-----QTNDETKADEKYEEQIYR-LGTTASNHL-TSEAGVDRLIILGVGTGAVWAAKYVEKFQAEQ-------------------DLRLVMIDARQPIST-----------DAPDLLEILP----NLAVTIIDLHHSP----QFNS-----RDAAAQEFPGQRLRLA--RHKRMNAYHQSRLPAQPV-NW-KSSNTRLLKHTRGLINTY-IIKAEQEQRNIKLNNDEQA--------------------DSEKAPG----------------- =====>
9past-e8kg34 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKKLNIATQSGTVLHGVLF-PAETKA--------------------KTIVIA-------------------------------------------------------------------------ITGIHGNFYSN----PF-YYNIGETLSKAGVDF---L---Y-----------AQTRNAFGKMQEVNAL-----------TNEPEIIGSFNEDFVKTIEDLTAYLDF-AEQQGYKNIVLAGHSLGANKVIYYLSETQDPR-------------------VSKFLLLSPANVTH----------------LTNFVG----EP---ERAYIRQM-------------------------------------------V------EK-GQGQKLLPFELFGWLPAT-ADTAYQ--------------------------------------------------------- =====>
aers4-a4sjy5 --------------------MQKSEPLARFFIDPLAALQKTGPPPLTQLTGERTMARLSL-SLLLLTLLA-------SGASQASE-----------------------------------------------------------VTPPA----------PLDYWQNSDWQGLP-----DST----QID-------KQTVLFAKHDSDSYVGLAILLPDWQR----SGQLWQLTRALG-RLGFDTLLLLPSPQQAELDPAA-------------------------EKKQ------------------------------------------------------------------------------------------------------------------QAIDDFRKQFA-AR-IIK--LGDA-KLQE-GGFKLILAQGTSAAWATNLIASEQVPA-------------------PDALVLLDGFFPNV------Q-----SNQTLAKQVA----QATIPTLDLYQEE----GGRW----PLLAA-----EARRSES--RRSHKLNYRPYALMELDETPTRIQGWLTHLGWL----------------------------------------------------------------------- =====>
celju-b3plp7 MLPPVTRRL-PSWCSH------------------------------------------GRMKTIACGLLI--LAMK---TP-----CLAQTPPS-------DPT------------------------------PPPT--NTTVSESSS-----SSTSSLSTLDRRLRAKELLADAL-TEESHWLET---TE--GKILALFRPTEDKVTKGALLLLHAAEDPQSWPPELENLRQKLP-QYGWETLAISLPQAYAPEPPKRELAP---AVESQ-------SSSSQAD--------------DPNTS--------TN----------------------------AETTNAS--------------------------SSQSSSSTP---------------TEDKPHTVAREQLIKAY-ILA--ALNF-LNQKGRFNLVVLVDNSSLYWCMQLLSPSIKT---------NTRDPNTVDGPLQALVITNLQPQEPL-----------TTAELEASFS----QSQLPVMDIFFGP----DNSV-----QQA----QRDKHRAVA--MRNKLQHYQQTLLEAQPKVVE-DDSNSFLLARIRGFMEKK-ARGTEIQAKEVKNQP------------------------------------------------ =====>
colp3-q47vk3 MR------L-KSFKEKQLH-TTSPHNVSRNKISSI------------------PLVLFICMLTFICSPLT-------FAEEQKTDASA---E-NTQK----T-ANKV-----T-----------------------------PIKKPI----------ELTQQYKEDLKHYLT-----DEQVKPLLAG---P--DDYLTLVKRYTSANGKGVVILLPEWQQGATNPKAINYLRNALP-AKGWSTIAIQPSNKPENYPS------------------------------------------------------------------------------------------------------------------------------------TEITV-AEQKKENQLVLKEYKSKLNSM-LNA--VMNT-AREY-PGIVLVIAQGNNAALLVDIYSQDDSQQ-------------------PNALIMLSSYRQSN------HALINGVNENFARQVA----STELPILDLYLKH----DNPL----VLNKA-----AQRRAFS--KQEMKVYYRQRQLNNTVTG---YYPEEELLSQINSWLKAIGW-------------------------------------------------------------- =====>
comt2-d0iwr7 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDP--GADSPD-----------------------------------------------------------------------------------------------------------------------------------------------SPELAASFPEAYQR-IQS--AIEYLKMQKGVERVYLMGHSMGGRMTTGFLANNPTAP-------------------VVGFIGVGLTAGG--K----------EPVNTNLNLR----KVKLPVVDVYGDN----EMDA------RAA-----SFRKSL------VSENFVQVEVPGAKHDYRGY--EKPVSDIVIEWLKKR-EGR------------------------------------------------------------ =====>
comte-d8d555 -----------------------------------------------------------MSVLKSLIWV---FS-----CVLA--------------------T--------------------------------------P---------------V----------AAQM-----PQ-GEYLDGK-------------------DSKVGVVLAHGRGNSPDGNVV-GPLRRAIHKDLGFHTFSLRMPDP--GADSPD-----------------------------------------------------------------------------------------------------------------------------------------------SPELAASFPEAYQR-IQS--AIEYLKMQKGVERVYLMGPSMGGRMTTGFLANNPTAP-------------------VVGFIGVGLTAGG--K----------EPVNTNLNLR----KVKLPVIDVYGDN----EMDA------RAA-----SFRKSL------VSENFVQVEVPGAKHDYRGY--EKPVSDIVIEWLKKR-EGR------------------------------------------------------------ =====>
ferbd-e1slj2 --------------------------------------------------------MFRCLFLLLL----------------------------------------------------------------------------------------------------------------------IALP---C--HAIERKAFPAEAPGSKGTVIVLADAGAVVDSGHWQRTLLRTLP-RHGWRALSVAQYDGLSSLP------------------------------------------------------------------------------------------------------------------------------------------------------------------------EA-LQSE-PEPHYWVVSGATAGEAVNAMATQQLPL-------------------PAGLVVLGPFRQTP------A-----ENDALPAQLA----ELGIAVLDMSGPG----DHPL----AQATT-----EARQQAN--RRTANPHYRAMDWALDWDQ---SA--DTLAQRIRGWLKQQKTSPQ----------------------------------------------------------- =====>
hahch-q2s9b5 -------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLSLAKSLP-----GSQVLWLNGKQGDA--SAMLALYRPANVAEQQGAVMLLHDRGQHPDWPQFIHSLRNELP-DEGWHTLSIALTPPAEAKTPKRVLLS---ASDKEFPYAPKKPAADNA----------------PEKS-STRQLETLT---------------------PEQLAETNEATEQL--EQQQAVEGVD--------------IDVSGEGDTVEET--------------AEKPVEATVGNTER-IEL--GMQQ-LSAFGQENKVLLGVGSGVDAMLRYVLANPQSM-----------------ASGLSMVWINAEVSEGL-----------LDEIKEKAQG----FFSLQVLDLYDSA----LDLQ-----SRNA-----MQRRDFA--RRNGMEGYRVEGMSGLSL-IP-SSENGQVTRKVESWLTFH-APGMKKQTKRL---------------------------------------------------- =====>
idilo-q5qvn0 -----------------------------------------------------MKRYLIILL-AVVFI-------------------------------------------------------------------------------------------SPAVSQDDLERYLP-----QDQIHWLTGD--DD--ERYLALKKEYLQAFERGQIVLLPDWHYHPLQSFYIRPVYENAP-NFGWTTWALTPPDNDIRTDNLQT------PATT----------T------------------------------------------------------------------------------------------------------------------HFPDAADEEVFTPLVSALQQR-MTL--LLDE-TLDR-PGFSVWVVEGITADIALRLLESEPSIM-------------------PDAIVLVNAYVPQF------Q-----YNRALADRIS----QSQLPVLDIRSAE----GNRW----VGEHW-----SLRKKLA--NKYQHPAYRQRQLVNSGN-----AGQRELTSTIKGWLEFHGF-------------------------------------------------------------- =====>
legln-d3hld6 ------------------------------------------------------MKYTIRIMLLWCCIASAAYTNM---L---------------------------------------------------------------------------------EINVDGKHIHV---------PCWFSQ-------------------KKQLGAVLLVAG-GSDVRSSTVLDDLVHRLA-ENGWMVTLLQDDKNNAIP--------------------------------------------------------------------------------------------------------------------------------------------------W-----------IKQ-LPS--AIVT-LRQKKFMKIVVLHYGDQLQQTLDYFGKPQVPK-------------------IEGLILLSAYHTQL----------------TINKKP----EINVPIFDIIGQF----DHGL----VKQEL-----AIRQKM---FGNNKKKYLAIEIPEIEP-DY-KYTRQLLFTFINGWMMKL-PEFQEASPNFMYTYQYFQPR-DEHVLRS----------------------------------- =====>
leglo-d1rjf4 ---------------------------------------------------------------------------M---L---------------------------------------------------------------------------------EINVDGKHIHV---------PCWFSQ-------------------KKQLGAVLLVAG-GSDVRSSTVLDDLVHRLA-ENGWMVTLLQDDKNNAIP--------------------------------------------------------------------------------------------------------------------------------------------------W-----------IKQ-LPS--AIVT-LRQKKFMKIVVLHYGDQLQQTLDYFGKPQVPK-------------------IEGLILLSAYHTQL----------------TINKKP----EINVPIFDIIGQF----DHGL----VKQEL-----AIRQKM---FGNNKKKYLAIEIPEIEP-DY-KYTRQLLFTFINGWMMKL-PEFQEASPNFMYTYQYFQPR-DEHVLRS----------------------------------- =====>
legp2-d5t7l7 ------------------------------------------------------MNQIKWIVLLFCFVVSNVFADK---L---------------------------------------------------------------------------------DITVDQKKIIL---------PYWLSR-------------------SVSYGAVIIVSG-GETAQWSLLLEQFAKGLS-RNGWSVVLLNCTKNNSIP--------------------------------------------------------------------------------------------------------------------------------------------------W-----------INQ-LPE--VIST-LRQNNNKRIVLVHYGDQLNLALEYFSKPQSKM-------------------INGLVMLSAYDLNR----------------NLQKVP----RLRFPLFDIVGQF----DYDM----VRQQR-----KSREEK---FKE--NSYLAIDIPGATH-DY-QYSQQLLLAFVHGWMAKL-PEFEPQPPPILVSYLEPVYSTASSIVSTN-KLDYQPLVSQINS-------------------- =====>
legpc-a5iee3 ------------------------------------------------------MNQIKWIVLLFCFVVSNVFADK---L---------------------------------------------------------------------------------DITVDQKKIIL---------PYWLSR-------------------SVSYGAVIIVSG-GETAQWSLLLEQFAKGLS-RNGWSVVLLNCTKNNSIP--------------------------------------------------------------------------------------------------------------------------------------------------W-----------INQ-LPE--VIST-LRQNNNKRIVLVHYGDQLNLALEYFSKPQSKM-------------------INGLVMLSAYDLNR----------------NLQKVP----RLRFPLFDIVGQF----DYDM----VRQQR-----KSREEK---FKE--NSYLAIDIPGATH-DY-QYSQQLLLAFVHGWMAKL-PEFEPQPPPILVSYLEPVYSTASSIVSTN-KLDYQPLVSQINS-------------------- =====>
legpl-q5wua5 ------------------------------------------------------MNQIKWIVLLFCFVVPNAFADK---L---------------------------------------------------------------------------------DITVDQKKIIL---------PYWLSR-------------------PVSYGAVIIVSG-GETAQWSLLLEQFAKGLS-RNGWSVVLLNCTKNNSIP--------------------------------------------------------------------------------------------------------------------------------------------------W-----------INQ-LPE--VIST-LRQNNNKRIVLVHYGDQLNLALEYFSKPQSKM-------------------INGLVMLSAYDLNR----------------NLQKVP----RLRFPLFDIVGQF----DYDM----VRQQR-----KSREEK---FKE--NSYLAIDIPGATH-DY-QYSQQLLLAFVHGWMAKL-PEFEPQPPPILVSYLEPVYSTASSIVSTN-KLDYQPLVSQINS-------------------- =====>
legpn-e1y2m5 ------------------------------------------------------MNQIKWIVLLFCFVVSNVFADK---L---------------------------------------------------------------------------------DITVDQKKIIL---------PYWLSR-------------------PVSYGAVIIVSG-GETAQWSLLLEQFAKGLS-RNGWSVVLLNCTKNNSIP--------------------------------------------------------------------------------------------------------------------------------------------------W-----------INQ-LPE--VIST-LRQNNNKRIVLVHYGDQLNLALEYFSKPQSKM-------------------INGLVMLSAYDLNR----------------NLQKVP----RLRFPLFDIVGQF----DYDM----VRQQR-----KSREEK---FKE--NSYLAIDIPGASH-DY-QYSQQLLLAFVHGWMAKL-PEFEPQPPPILVSYLEPVYSKASSIVSTN-KLDYQPLVSQINS-------------------- =====>
marah-e4pqz2 --------------------------MQRFEIY------RPG------VF-----WLF--ILALMCVAP---------SITLGQEESGT----------------------------A--------------GEAEGV----EASESA------SRALIWTGTGERSLIQRFP------ESAVWLELEEGDR----ALGLFYPEARLPARGAVLVLSDEGETAA-SGVTGSLAAGLA-SRGWAVLTLGLESPSPVLSEFLMRPVM---------------------EPPAAE-----A---GAGEEGA----------------------------------------------------------------------------S---DSVMIDV-MASSESADDLEARYRSRINQM-LQA--GLAL-LVERGYEAPAVLGVGRASIHVTNRV--LDGAD-------------------ASALIWVVPQFYPV------------DRSGLPDRLES----LGTDLLELYPQG----TA------DDQSG-----WSIGMQL--RRAGMSGFERQPIAWISPA--PETLGDGVASRVAAWLESRER-------------------------------------------------------------- =====>
marav-a1u6g5 -------------------------------------------------M-----VLK--AIRLLCLFLI----SGWLNAAVAQDEAKG----------------------------G--------------EEAEPA----TKANPA------SRSGFSTGLGEWALVRRYP------EQAVWLDLDDEGR----ALGLFLPEYVTPATGALLILADEGQTAD-EGVLGSLRVALA-ERGLAVMTVGLGLPPEAIRRHRMDVMAPGL------------------DDDAGQ-----N---PDQGGNT----------------------------------------------------------------------------S---DSVMIDV-AE-EPPFDDLTADFRNSVRTI-LSA--GVAV-LQQRGYERVGVLGMGWSADYVTDWA--ADAAA-------------------VSAVVWLAPRFPAR------------QAVTLPSLLKERNGGQGWPVLDLHDSA----GP------SGAEG-----RARAAAF--ARADVAGYDRQPVALNRPL--RAEDARRVASRVSAWLKNLSASGD----------------------------------------------------------- =====>
marms-a6vu58 -----------------------------------------------------MKKFTALRHAIIALLS--LSTNT---ALFA-EESQA-APGST------------------TT-----PQQTTPVQTTPTQNAKEY----IIPK-------------PQASRIDALKASLT-IRRLDHQIQTLEA---NG--EPFLALYRLSLTSSTQGCIIMLHSDNEHPDWPDAIAPLRDAMP-EHSWCTISIEVPDIIKRAEP-VKITT---ATAEN---------------------------------------------------------------------------------------------------------------------------------TSSPKELPNQTLVFAR-IQA--TMDY-AKTQGIEQFTFLGYGTGASYALGFLAANKNA--------------------GKALTLIDIESPPNL-----------SDYEVAQQIR----QIEQPILDYYVDK----TGND------QFA-----VWRKQAANQRTDKVGDFIQVNALPDRV-T-GKNSKQLLIQRVRGFLKQN-TNQINQLKSLPSVKKGLFYG------------------------------SPIIN-------- =====>
pse14-q48nt0 -------------------------------------------------MEYPMSYTFRATFPALFLSLVLPCALP---VLAA-DPA-----------------------------------------PA-KDAAAEA----PVERAPL-----L---SRSQEDAIALERQLP-----REDQQQLQA---GD--ESFLALWKPANSDEPQGAVIIVPGDAESPDWPDAVGPLRRKFP-DVGWSSLSITLPDAIDNSLVPREPDA---A---------S-TDANAAK---------------P--K---------E-------------------SPKDASAKAQDPAAEA-------------------------------EA--LAAAATAKA------AADEELNKAQAERILAR-IES--AISF-AQQNKARSIVLIGHSSGAYWAARFLNERTSPA-------------------VQKLVMLAAREPVN------------AAPSLLDMVP----QLKIKTADFIYKN----SP-------DQAA-----KARLQAS--KRAKGPGFTQIGLINIVG-NE-DTEQEQLFRRVRGWIDAK-EEK------------------------------------------------------------ =====>
psea6-q15p56 MN------I-SFF------------NRSKIFLDDIFI---------------PALHAFMHNVALGCMLLV-------PSM-------------------------------------------------------------------------------TSASTLTDVQRQLF-----PDKAKILQAN---N--KSTVIIESQNTTSNLNGVAILVGETGRPPSSQQNLAMLTQYLN-DLGWVTMQITPPTIGFEPDLTDE------KTTA----------PDSQSQAST--------------TDESQDNTA-N-----------------------------DETEAA-------------------------------QETPTPANSSPASPQYQLHQISNGHFLQHEQELRGL-MQA--AMAR-AQSY-SGFRLIIAQGTSAAWLIKIYAEKQIPS-------------------PDALVTISPFWPQR------N-----LNALIANYTA----VTEMPLLDIYSPQ----DNNW----SLMSA-----TQRGIDA--SKNLKLDYRQRQLTNTFNT---FSDSAFVSKEIYGWLHYLGW-------------------------------------------------------------- =====>
psea7-a6uza3 -----------------------------------------------------MP---VLRHPPKPFALLLATSLL---WPAA-AHA-EE--------------------------------------ES-AKEQPP-----AMERPAV-----S---ERSQDEARGLERQLP-----EESQQILKA---GD--ESFLTLWLPANSAEPEGVVILVPGDGESPDWPQVIGPLRRKLP-DAGWQTLSLALPDPQSSAPVTRPAGS---A---------A-SASADKDAS----------AIDSASK---------T-------------------EVKGESGNAPAAESTA--------------------------EAGSGEPAQSDERPTPPA------IDPVEQRKAHAERVMAR-LQA--TIDL-ALQHEPKSVVLLGHGTGAYWAARYLAEKEPSE-------------------IHNLLLVAPELPRD------------FRPPLEDMVP----KLKLATGDFYYRD----TRAD-----RDAA-----RLRMQAG--KRQKHPAYIQVAMQALPA-DP-EAEQEQLYRRIRGWLGLH-LQAAAQKPME----------------------------------------------------- =====>
psea8-b7v4i5 -----------------------------------------------------MPAFSLLPKPSALLPLLLAAAFL---PPAF-VHA-EE--------------------------------------EA-AKDQPPA----PVERPAV-----S---ERSQDEAKGLERQLP-----EDGQQILKA---GD--ESFLTLWLPANTAEAEGVVILVPGDGESPDWPQAIGPLRRKLP-DAGWQTLSLALPDPQSTAPVTRPAES---A---------A-SASADKDAS----------AADSASK---------P-------------------DVKGESGNAPAPESTA--------------------------QAGSGEPAQSEDQAPPPA------IDPVEQRKAHAERVMAR-LQA--SIDL-ALQHEPKSVVLLGHGTGAYWAARYLAEKEPAE-------------------IHNLLLVAAEVPRD------------FRPALEDMVP----KLKLATGDFYYRD----ARAD-----REAA-----RLRMQAG--KRQKHPAYVQIAMQALPA-DP-KAEQEQLYRRIRGWLSLH-LQADAQKPAE----------------------------------------------------- =====>
pseab-q02tg4 -----------------------------------------------------MPAFSLLPKPSALLPLLLAAAFL---PPAF-VQA-EE--------------------------------------EA-AKDQPPA----PVERPAV-----S---ERSQDEAKGLERQLP-----EDGQQILKA---GD--ESFLTLWLPANTAEAEGVVILVPGDGESPDWPQAIGPLRRKLP-DAGWQTLSLALPDPQSTAPVTRPAES---A---------A-SASADKDAS----------AADSASK---------P-------------------DVKGESGNAPAPESTA--------------------------EAGSGEPAQSEDQAPPPA------IDPVEQRKAHAERVMAR-LQA--SIDL-ALQHEPKSVVLLGHGTGAYWAARYLAEKEPAE-------------------IHNLLLVAAEVPRD------------FRPALEDMVP----KLKLATGDFYYRD----ARAD-----REAA-----RLRMQAG--KRQKHPAYVQIAMQALPA-DP-KAEQEQLYRRIRGWLSLH-LQADAQKPAE----------------------------------------------------- =====>
pseae-a3kzj8 -----------------------------------------------------MPAFSLLPKPSVLLPLLLAAAFL---PPAF-VQA-EE--------------------------------------EA-AKDQPPA----PVERPAV-----S---ERSQDEAKGLERQLP-----EDGQQILKA---GD--ESFLTLWLPANTAEAEGVVILVPGDGESPDWPQAIGPLRRKLP-DAGWQTLSLALPDPQSTAPVTRPAES---A---------A-SASADKDAS----------AADSASK---------P-------------------DVKGESGNAPAPESTA--------------------------EAGSGEPAQSEDQAPPPA------IDPVEQRKAHAERVMAR-LQA--SIDL-ALQHEPKSVVLLGHGTGAYWAARYLAEKEPAE-------------------IHNLLLVAAEVPRD------------FRPALEDMVP----KLKLATGDFYYRD----ARAD-----REAA-----RLRMQAG--KRQKHPAYVQIAMQALPA-DP-KAEQEQLYRRIRGWLSLH-LQADAQKPAE----------------------------------------------------- =====>
pseae-a3li53 -----------------------------------------------------MPAFSLLPKPSALLPLLLAAAFL---PPAF-VQA-EE--------------------------------------EA-AKDQPPA----PVERPAV-----S---ERSQDEAKGLERQLP-----EDGQQILKA---GD--ESFLTLWLPANTAEAEGVVILVPGDGESPDWPQAIGPLRRKLP-DAGWQTLSLALPDPQSTAPVTRRAES---A---------A-SASADKDAS----------AADSASK---------P-------------------DVKGESGNAPAPESTA--------------------------EAGSGEPAQSEDQAPPPA------IDPVEQRKVHAERVMAR-LQA--SIDL-ALQHEPKSVVLLGHGTGAYWAARYLAEKEPAE-------------------IHNLLLVAAEVPRD------------FRPALEDMVP----KLKLATGDFYYRD----ARAD-----REAA-----RLRMQAG--KRQKHPAYVQIAMQALPA-DP-KAEQEQLYRRIRGWLSLH-LQADAQKPAE----------------------------------------------------- =====>
pseae-e3a5g5 -----------------------------------------------------MPAFSLLPKPSALLPLLLAAAFL---PPAF-VQA-EE--------------------------------------QA-AKDQPPA----PVERPAV-----S---ERSQDEAKGLERQLP-----EDGQQILKA---GD--ESFLTLWLPANTAEAEGVVILVPGDGESPDWPQAIGPLRRKLP-DAGWQTLSLALPDPQSTAPVTRPAES---A---------A-SASADKDAS----------AADSASK---------P-------------------DVKGESGNAPAPESTA--------------------------EAGSGEPAQSEDQAPPPA------IDPVEQRKAHAERVMAR-LQA--SIDL-ALQHEPKSVVLLGHGTGAYWAARYLAEKEPAE-------------------IHNLLLVAAEIPRD------------FRPALEDMVP----KLKLATGDFYYRD----ARAD-----REAA-----RLRMQAG--KRQKHPAYVQIVMQALPA-DP-KAEQEQLYRRIRGWLSLH-LQADAQKPAE----------------------------------------------------- =====>
pseae-q9i5t9 -----------------------------------------------------MPAFSLLPKPSALLPLLLAAAFL---PPAF-VHA-EE--------------------------------------EA-AKDQPQA----PVERPAV-----S---ERSQDEAKGLERQLP-----EDGQQILKA---GD--ESFLTLWLPANTAEAEGVVILVPGDGESPDWPQAIGPLRRKLP-DAGWQTLSLALPDPQSTAPVTRPAES---A---------A-SASADKDAS----------AADSASK---------P-------------------DVKGESGNAPAPESTA--------------------------EAGSGEPAQSEDQAPPPA------IDPVEQRKAHAERVMAR-LQA--SIDL-ALQHEPKSVVLLGHGTGAYWAARYLAEKEPAE-------------------IHNLLLVAAEVPRD------------FRPALEDMVP----KLKLATGDFYYRD----ARAD-----REAA-----RLRMQAG--KRQKHPAYVQIAMQALPA-DP-KAEQEQLYRRIRGWLSLH-LQADAQKPAE----------------------------------------------------- =====>
psee4-q1ig13 -----------------------------------------------------MFTLYRTTLAMFCLASLLPFGAQ---AADT-EKT-----------------------------------------EA-AT-EAAA----PAPRPAL-----A---ERSQDDALALERQAP-----KAEQQTLQA---NG--ENFLALWKPANDSDPKGAVIIVPGAGETADWPNTVGPLRRGFP-DVGWHTLSLSLPDLLAERPQARVEAK---Q---------A-VATQKPE-G----------ESAP--A---------K-------------------DTP---ADANANVAQA--------------------------TAPEVEA----AESTDAA------EADEHSDQADAERIFAR-LDA--AVAY-AQQQKARSIVLLGNGSGAYWAARYLSEKQPPQ-------------------VQKLVMVSAQTPAR------------VEQDLQSLTS----NLKVPTADIYFAG----RPQD-----SQAA-----QLRLQAS--KRQKDSQYRQVSLMAMPG-NK-AAEQEQLLRRVRGWLTPK-EE------------------------------------------------------------- =====>
psef5-q4k4y2 -----------------------------------------------------MPLVHRSALPALCLSLILPWTFS---VQAA-DPAPE------------------------------------------TKTPEEQ----PAQRQPL-----P---ERSQKDAAALERQLP-----ALEQQQLQA---GG--DTFLALWKPANTSDPKGVVIILPGAGETADWPQAIAPLRNKLP-DTEWASLSLTLPDMLSEAAQPRVVEA---A---------P-VPTDKANTA----------KDAS--T---------E----------------------------AKPIEQV--------------------------AGGEADV----ADRVVA-------ESTEEQIKADAERIFTR-VDA--ALAF-AEQQNARSIVLLGHGTGAYWAARYLSEKQPAQ-------------------VQKLVMVAAQSPAN------------GKPQLAEITP----TLKLATADFFYVD----KPLA-----QKAA-----LERLQAS--KRLKHSNFSQIPLKALPG-NN-TAQQEQLFRRVRGWLNPQ-NTDS----------------------------------------------------------- =====>
psefl-e2xz59 -----------------------------------------------------MPFFHRSALPALCLSLLFTSAFS---VQAA-DTP---------------------------------------------EPVAEK----PVERQPL-----P---QRSQEEASALERTIP-----QQQQQQLQA---GS--DSFLALWKPANSAEPEGVVIIVPGAGENADWPQAIGPLRHKLP-DANWSTLSLSLPDVSVDTLPPRVMEA---P---------K-AAV--DTSS----------KDAS--T---------A----------------------------DKPIEQA--------------------------AGAEAEG----TDPAVV-------PGAEEQDKTDASRIFDR-IDA--AVAF-AQTQGARSVVLLGHGTGAWWAARYLSEKQPSQ-------------------VQKFVMVAAQTPTG------------RHPDVQQLAP----GLKLPTADVFYQD----TAQS-----RKNA-----RERAQAA--KRLNNDGYKQVTLKTLPG-DS-AAEQEQLYRRVRGWLSPQ-KTVD----------------------------------------------------------- =====>
psefl-q5rll4 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLLGHGTGAYWAARYLSEKQPSQ-------------------VERFVMVAAQTPTT------------AKPALAELTS----TLKLATADIFYMD----KPLD-----RNAA-----LERLQAS--KRLKGSTFSQVSLKALPN-P--AAEQEQLFRRVRGWLNPQ-KAGE----------------------------------------------------------- =====>
psefs-c3k320 -----------------------------------------------------MPFLHRSALPALCLSLLITSAFS---VQAA-DAP---------------------------------------------EPAAEK----PVERQPL-----P---ERSKEEASALERKIP-----QQEQQQLQA---GS--DTFLALWKPANSAEPEGVVIIVPGAGENADWPQAISPLRHKLP-DANWGSLSLSLPDVSVDTLPPRVMEA---P---------K-ATV--DTSS----------KEAS--T---------A----------------------------DKPIEQA--------------------------ASAEAEG----TDPAVV-------PGADEQDKTDASRIFDR-IDA--AVAF-AQTQSARSVVLLGHGTGAWWAARYVSEKQPSQ-------------------VQRLVMVAAQTPTG------------RHPDVQQLAP----GLKLPTADVFYQD----DAQS-----RKNA-----LARAQAA--KRLKNEGYKQVSLKTLPG-NS-AAEQEQLYRRVRGWLSPQ-ATSD----------------------------------------------------------- =====>
pseht-q3ifd8 -----------------------------MVLAQ-------------------YLKVIKLNVLLSCALIL-------TVQ------------------------VTA-----A-----------------------------EHIAPP----------SYASIENNDIQHLLP-----NDEIKPILAG---D--TEFLTLYSEYMSADFRGTVLLIPDWQSSATNNAGMSFLRKELN-NLGYTTYAMTVPDINWQASEVAT------AATN----------ENTATESTSAENILAQSSDNA< |
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