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MSA from Cobalt (Ncbi) Cobalt
Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....790..5....800..5....810..5....820..5....830..5....840..5....850..5....860..5....870..5....880..5....890..5....900..5....910..5....920..5....930..5....940..5....950..5....960..5....970..5....
9tryp-q380z6   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYSYFCF------SSMQVQDKKIHLNIMVKVLCLH------GFGQTGEIFEHQ-LNRLCVKLSS----------VAE-----FDFVDAPYPLPHDHTGSNS---------------------------------------------------IATYSWCRQPCGEEPS-EA--------------------DDDYS-----------IGDAVVKRHMAA------------------------------------EGMRY---DV-ILGFSQGGLVAARYVMLRELH----------------------------------GGDGYGPPLKGLILAATPDPRRTFPGLASAFK-DSAR-------------------------Y--------------------------------------------DAEND-----GFLGPLPSLH--IVGRK---DGVVDPAESASF----ADA------CRP--------H-ADVLWHEHA-----HSFPTL-QNI-----VMSLKSFFERIAQRNPGND-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aedae-u483     	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMANET------AAK------STKSSPTPAVEPESKLKILALH------GYRQNGDGFKSK-LGSFRKFIGK----------HAE-----LVFVTAPHIAPPLPDSE-----------------------------------------------AGTEPDPAQRSWWFNKDD--------------GTF-------------KGTNKNGPAIGFEDSLKLVEKVWKQ------------------------------------EQ--C---CG-LLGFSQGACFVGLLCDLSARGM------------------------------------TSI-KPEFAVLSSGFRSGSLV--HLNCYE-------------------------------------------------------------------------------------TKV-QIPSLH--IYGEA---DEIIPKEMSMAL----ADT------FT---------D-PQILTHPGG-----HFLPAQ-ASQ-----KQTYVEFFRERLQFHLEAQEIENATAANSILVDDSGPAG-----------------------NGVHDDDDD----DD---DSD-------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoga-q7qbj0   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKLKVLALH------GYRQNADSFKSK-LGSFRKMLNK----------YVE-----FVFVSAPHPAAPLE--A-----------------------------------------------VGGEPDPNQRSWWFNKDD--------------RTF-------------KGTNQGGPAYGFDESLRLVERTWQA------------------------------------EG--C---HG-LLGFSQGACFVGLLCDLSARGM------------------------------------TTM-KPQFAVVASGFRSGSLV--HLNYYE-------------------------------------------------------------------------------------NKV-QIPSLH--IFGET---DEIITKDMSEAL----AET------FL---------D-PEVVTHPGG-----HYFPAQ-ASL-----KETYVDFFRDQLQQHLEAKELQNATEENSFHLEGQEEAEESALQP---------------VHEGLQNGSD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
arath-AT4G24380	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG------------------------SEGRSIARKPRFLCLH------GFRTSGEIMKIQ-LHKWPKS---VI------DR-LD-----LVFLDAPFPCQG--------K---------------------------------------SDVEGIFD--PPYYEWFQFNKEF-TEYTN----------------------------------FEKCLEYLED------------------------------------RMIKLG-PF---DG-LIGFSQGAILSGGLPGLQAKGIA----------------------------------FQKVPKIKFVIIIGGAKL---------------------------------------------------------------------------------KSAKLAENAY------SSSLETLSLH--FLGET---DFLKPYG--TQL----IES------YKN----------PVVVHHPKG-----HTVPRLDEKS-----LEKVTAFIDTLEHLVMEEDKNGEEN---T---S---------------------------K-P-------T-K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
arath-Q9FKP9   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPEIHLKPKNPRILCLH------GFRTSGRILQAG-IGKWPDT---IL------RD-LD-----LDFLDAPFPATG--------K---------------------------------------SDVERFFD--PPYYEWYQANKGF-KEYRN----------------------------------FEECLAYIED------------------------------------YMIKNG-PF---DG-LLGFSQGAFLTAAIPGMQEQGSA----------------------------------LTKVPKVKFLVIISGAKIPGLMF----------------------------------------------------------------------------GEPKAAVNAF------SSPVRCPSLH--FIGER---DFLKIEG--EVL----VES------FVE----------PVVIHHSGG-----HIIPKLDTKA-----EETMLSFFQSIRQMLSDESGSVRSL---M-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
arath-at1g09280	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRKLRILCLH------GFRQNASSFKGR-TGSLAKKLKN----------IAE-----LVFIDAPHELQFIYQTA------------T----------------------------------PPSGVCNKKFAWLVSSDFDKPS-ETGWTVAQ-CQF-------------DPLQYQTQTEGFDKSLTYLKTAFEE------------------------------------KG-PF---DG-ILGFSQGAAMAAAVCGKQEQLV------------------------------------GEI-DFRFCVLCSGFTPWPLL----EMKE-------------------------------------------------------------------------------------KRSIKCPSLH--IFGSQPGKDRQIVTQASSDL----AGL------FED--------GCATIVEHDFG-----HIIPTK-SPY-----IDEIKAFLYQFI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
ashgo-q756b1   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSNSADRKILALH------GFAQSDAIFCSK-TGGLRKELIKL---------GYE-----VCYPCGPVKLK-RSDANSFQAET------------------------------------------PPVQDIDVYGWYNAKEQN-------------------------------------Y-SIETALESLRDYIIK------------------------------------NG-PF---VG-ILGFSQGCALGGYLCTGIRDILGL--------------------------------TEEQQPDLEFFIGFSGYRLPPKE----------------------------------------------------------------------------------LYDRFDQ-----HPPTIPSLH--IMGEL---DTVTEESRVQEL----YDC------FPI--------ESRTLLKHAGG-----HFVPNS-KSF-----VAKVATWIRALNYLSSASIPPTP--------NPPQ-------------------------------------SAEETPALEDELMDI--------IDSL-----------GTA-------------------------------------------------------------------------------------------------------------------------------------     =====>
ashgo-q75c41   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARLLFLH------GFLQNGRVFSEK-SSGLRKLL-KK-----A---GVQ-----CDYIDGPVELQ-PADLPFSV------EA----------------------ERW-----------SATVDAGMNRAWFHHTD---V---------------------------------SADLNVADALETVAAHIRA------------------------------------HG-PY---DG-VVGFSQGAALAAILTNRLCDLVPG------------------------------------HPPLKVGLFVSGYSFTEPDPVA--------------------------------------------------------------PQALRIA--------ARHQQAFAP----PPGQPTQVLF--LYGAA---DAAVPAARSKYL----QDI------YVKAYGE----DQVKGFEHPGG-----HMVPNK-KEI-----IRPIVDEIAKALGLP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspfu-q4wim6   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVLCLH------GKGTSGAIFKSQ-T-------------------------------DGCYPSTAAAGIDL----------------------------------------F-----YP-APY---YSFW--ED-D-----------------------------SP-------EAITKTCTWLKGLIAE------------------------------------RG-PY---DA-VMMFSQGCALGTAMLLLH---QAQD--------------------------------PTQPPPFKAAIFICGGPPLKLLE--------------------------------------------------------------------------------------------------------SIGFE---VS--------DA----VKE-------------------------------------------------------RDRAGRE---------------------ALATQAHS-------ASILARGS-ARWMGDAS---RGGAVDE----EELRGAI------------------------------------------------RGPFTVGVPTVHVYGSKDPRY--AAGVQLSGICEPGKRRVFDHGGGHEI------PRTDRVSRTIAELVRWVLLEASA--------------------------------     =====>
aspfu-q4wr32   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSPETKPAIICLH------GHGSNGEIFQAQ-SQNLTRVLSP----------RFR-----FVFLDSPITTAQTGVGVP-P-------------------------------------YY-----AHIKPY---RRWHQDRNTI------------------------GLFDVTAEDVERERRAVRDSLKDVIERERR------------------------------------NG-PGAGVVG-VMGFSQGTRVATAVCLDS---EL-------------------------------------GRDIRFAIMICGICPSLALSAAETQVS--------------------------------------------------------------------------------------RPLDIVPVH--VQGSG---DPWLAKGTRLSK----QYF------NQR--------L-ATVVRFKGR-----HEIPVT-TSD-----VQNIAEVMAEYWEQKRDT----------------------------------VLAVEVASEFAA--------------------------RMVSA-------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspfu-q4wwp7   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPRQPLKLLMLH------GYTQSGTLFHAK-SRALIKHITKAFPLH-----EVS-----AIYPTGPTRLN-PADIPGYEPPAEGSTV------------------------------------EQQQEQIEAYGWYRRSNTADP---------------------------------PLYIGLEGGLDAIAKVLRE------------------------------------EG-PF---DG-VIGFSQGAAMAAMVASLLEPG-RKEAFEHFADPKVASEGFEV-KEPVAGVAFPVSFEEAGHPPLKFALCYSGFRSPGPR----------------------------------------------------------------------------------YRPFYEN-----PPIQTPILH--VLGSL---DAVVDDTRSRAL----VEA------CAGD-----PEKEGKVVWHPGG-----HFLPSQ-RPY-----LDAAVRFIKEQLEGKQAKADAKED----------------------------------------------------------DVRDM--------DLPF---------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspfu-q4x0n9   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YINTEG-PF---DG-MMGFSQGAALATMLLLQ--------------------------------------PSASATPLFSCAVFMPLCEASARKG----------------------------------------------------------------------------VVRYLDPEVD------SCRVTTPTAH--IVGVN---DE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspor-q2twv2   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSASPL--------------P--TQFNTLDPASSCPRILCLH------GGGSNSQIFRIG-CRVLEAQ---LS------ND-AR-----LVYADGPFFAPP--------G---------------------------------------PLITGVFTEWGPFRSWLPPDLGV-GPGKGQGVKL----------------------IYEDPTDADMVIEQIHHSLQKAMED--------------------------DDRNGATG-PW---VG-LLGFSQGAKIAASLLFRQQTDPER------------------------------F---TSLPFFQFGTLAAGPAPLVWLGSRESH---------------------QVGGK---------------------------------------------SSLD-------------PLLRIPTLH--IYGTR---DHLVRSSA-DWL----YQC------CSP----------DSARLFVWE---GEHVMPTR-TRD-----VSAIAEMIIEVLRGLAN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspor-q2u4h9   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKQPLKLLMLH------GYTQSGPLFHAK-SRALIKHLTKAFPLH-----DVT-----ATYPTGPLRLN-PADIPGYEPTQET-----------------------------------------PTEPLEAYGWFRRSNTASP---------------------------------PEYLGLEDGLAAVAKVMSE------------------------------------EG-PF---DG-VIGFSQGAAMAAMVVSLLEPG-RKEAFARFLDANVASEGKGETDAVVAGVPFPKAFEGLSHPPFKFALCYSGFRSPGAR----------------------------------------------------------------------------------YRGFYES-----PALQTPILH--VLGSL---DAVVEESRSRAL----VEA------CAGD-----PEKEGKVVWHPGG-----HFLPSQ-RPY-----LDAAVRFIREQLEGGNK-KDAEEE----------------------------------------------------------DVNDM--------DLPF---------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspor-q2u6m9   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRFLCLH------GSGTSGEIFEIQ-SGGISQA---LE------AKGHR-----FTYIDGRLDSEP--------E--P------------------------------------E-LKGILD--PP--FYKHYPRDI-APGED----------------------------------LARAIEYTMD------------------------------------IIKKKG-PF---DA-VMGFSQGAALAGSMIIN-------------------------------------HAKTHDVPLFKAAVFICGAAPYESSG-----------------------------------------------------------------------------KETIQPTPG------EYLVNIPTTH--IVGKQ---DEIYDLS--MQL----YGL------CEP----------SKAEFYDHG---SRHLIPFD-GKN-----TEAMIAAIEKTIKRARTG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspor-q2u7i2   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDARNQ--------------------EYHKNTLHLPRILCLH------GGGSNARIFKTQ-CRVISQR---LE------PY-FR-----FAYAEAPFDSGP--------G---------------------------------------PDVLSVYAEYGPFVRWFPDPE--------------------------------------HNIDGRAAIKAINNSVKTAMDE--------------------------DDRSGATG-PW---VG-LLGFSQGAKLAASLMFRQQVRAEK------------------------------LGRAQAGSDWKFAVVMAGRAPIVNLDPDVFRSSMLS--------NT---SQIDLSGL---------------------------------------------PDVDD-LMGE------EHVLKLPTIH--VHGLA---DPGLYFHR-ELL----DDY------CSI----------DSVRVLEWD---GAHRVPVK-SAD-----VNPLIDQILRLAKEIGAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aspor-q2u8j8   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRILCLH------GRGTSAQIFKSQ-TTSFRSRLND------L---PIT-----FDFIDAPYPTTPASGIDL----------------------------------------F-----YE-PPY---YTFW--PD-D-----------------------------SP-------TSHQNARTWLLNHIAK------------------------------------NG-PY---DA-VLGFSQGCSLAALTLLLH---AHES--------------------------------PLTPPPFKAAIFICGGAPLPLLE--------------------------------------------------------------------------------------------------------ELGYT---IT--------PE----MRS-------------------------------------------------------RDTESRK---------------------KLSIQADS-------AAILAKGA-ERWGGGGD---AGEVVDE----ESVRREI---------------------------------E-----------RCGIGKVKIGVPTVHVYGRKDPRF--VAGVQLSGVCEGSVRQCFDHGGGHDI------PRSSAVSERLAELVRWVLEEGGVA-------------------------------     =====>
aspte-Q9Y7C9   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MR----------------------YQASPALVKAPRALLCIH------GAGCSPAIFRVQ-LSKLRAA---LR------EN-FE-----FVYVTAPFPSSA--------G---------------------------------------PGILPVFADLGPYYSWFESSSDN---NHN-------------------------------GPSVSERLAAVHDPIRRTIVD--------------------------WQTQHPHI-PI---VG-AIGFSEGALVTTLLLWQQQMGHL-----------------------------------PWLPRMSVALLICPWYQDEASQ------YMR---------NE---VMKNHDDD---------------------------------------------NDSKDTEWQE------ELVIRIPTLH--LQGRD---DFALAGSK-MLV----ARH------FSP----------REAQVLEFA---GQHQFPNR-PRD-----VLEVINRFRKLCVTAQTLE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
bovin-OVCA2    	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAQPLLRILCLA------GFRQSERGFREK-TGALRKALRG----------RAE-----LVCLSGPHPVVDAAGSEGARP-------DS----------------------------------GPCPPEEQPQGWWFSEQE------------A-DVF-------------LALEEPTACRGLEEALETVAQALNK------------------------------------LG-PF---DG-ILGFSQGAALAALVCALGQGGD------------------------------------PRFPLPRFVILVSGFCPRGLG-LMEPIMQ-------------------------------------------------------------------------------------GPL-SLPSLH--VFGDT---DGVIPSQESMQL----CSR------FD---------G-AVTLTHSGG-----HFIPAA-APQ-----RQAYLKFLDQFAD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caebr-q61yz4   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQPKLRILCLH------GYRQCDQSFRQK-TGSTRKLVKA----------LAD-----FEFVNGIHSVAVD------------------------------------------------------EHSETSRAWWFSNAD------------Q-MSF-------------SSREPTDVSVGFDESVNAVVKFIED------------------------------------NG-PF---DG-LLGFSQGASMVHLLIAKAQLGE------------------------------------IKLPGIRFAIFFSGFLSLSSK--HDTLTS-------------------------------------------------------------------------------------LRIKDFPSMH--VFGDS---DEIVARPKSEKL----ADQ------FDM--------E-PIRIAHEGG-----HLVPSM-SKH-----KERITQFLREQMAPIASA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caeel-C25G4.2  	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQPKLRILCLH------GYRQCDQSFRQK-TGSTRKLVKS----------LAE-----FEFVNGVHSVAVD------------------------------------------------------EHVDSSRAWWFSNNE------------A-MSF-------------SSRESTEVAVGFEESVAAVVKFIEE------------------------------------NG-PF---DG-LLGFSQGASMVHLLIAKAQLGE------------------------------------IKLPGIRFAIFFSGFLSLSSK--HDSLTL-------------------------------------------------------------------------------------LRIKEFPSMH--VFGDA---DEIVARPKSEKM----ADM------FDV--------E-PLRIAHDGG-----HVVPSM-SKH-----KEKIAGFMREQLDRKIENN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
canal-q5adx4   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKILCLP------GYLQNGSTFAAK-SSGIRKILTKK-----L---DCQ-----LDYVDPYHSIESWREFSFPIAANEEESD----------------------KTW-----------ASIVEKGNNVRWFEHKA---P---------------------------------GVNLGLDESVNYLVDYIKQ------------------------------------NG-PY---DG-IIGFSQGAAMAEIMTNTIRKLLPS------------------------------------HPDFKISLFISGFFLTEPISDDHSEGNR------------------QRINDITDLE--------------------------EYKSQVQIS--------PDMAKYFTP----PQDLNTQVLM--VYGDD---DNIVAPVRSKYA----STF------YKS----------VHMFPHEGA-----HYVPNK-KDF-----LEPIVKLFDKTLNEKPML------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
canal-q5akr2   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPKKNVTYKGKILFLH------GYTQSASLFYAK-TSALRKKLIKL---------GYR-----CVYLNGPYVLT-PADLPTTDSLSK----------------------------FGSAT--------TDTDDVTYRAWWVKKDKT-----------------------------------NDAINLDESIATIKNYIQK----GEIIADN-----DLKVEEE--------TEEEKKL-PI---VG-ILGFSQGAAFGGVVAHKFHELFET-------------------------------------DPLKFVVLYSGFKLDTSKKAG--------------------------------------------------------------------N--------DKYDEYYPQTEEEVKSGGFKYLH--VLGEL---DTVVAEDRGYSL----YEH------TKS---------SSDILKHPGG-----HFVPNS-KMY-----VDNVANWIEAHQNGSQSKSEAPED-------------------------------------------------------DIDSLLDM--------MDNF-----------GKA-------------------------------------------------------------------------------------------------------------------------------------     =====>
canga-q6fiw8   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKKVLMLH------GLAQSGEYFASK-TKGFAAELEKL---------DYE-----LYYPTAPNSFP-PADLPNGLLDE-----------------------------IDDKV----------SSQSGVIAWLQNKETG-----------------------------------DGYYIPETTINYLHNYIIE------------------------------------NG-PF---DG-IVGFSQGAGLAGYLVTDFNGLLNL--------------------------------TEEEQPPLKFLMAFSGFRFRGEE----------------------------------------------------------------------------------HQKQYK------NPISIKTLH--VHGEL---DTVTEPEKVQAL----YDS------CDS--------SSRTFLTHKGG-----HFIPNS-RGF-----LKKVVEWLNEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
canga-q6fkj6   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKILMLH------GFVQSDRIFSAK-TGGLRKALKKM---------GYE-----LDYPCAPILVD-KSSLMSSSSQKEVEAS------V--------------AKQFNTDLGV-----GKDGSENQLYGWWQRKAGGDF---------------------------------YSYEIPQNTLDFLRQYIVE------------------------------------NG-PY---DG-VIGFSQGGGMGAYLVSDLNNLLNL--------------------------------SKEQQPDLKFFVAFSAFRLEPEQ----------------------------------------------------------------------------------YAQHFKT-----HPISVPTLV--IQGEL---DTVVSETRVMSL----YDA------ILP--------QYRALLKHHGG-----HFIPNQ-KPF-----LNQVCGWIQSVTTNPSNDEDMDIDM--NSIKSSAK-------------------------------------SSSTQLQMDDDLLDM--------IDSM-----------GKL-------------------------------------------------------------------------------------------------------------------------------------     =====>
canga-q6fpw6   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTASAAPRLLFLH------GFLQNGKVFSEK-SSGIRKLL-KK-----A---DIQ-----CDYIDAPVMLE-KKDLPFEM------DD----------------------EKW-----------AATLEADVNRAWFYHSE---I---------------------------------SKELDLTEAINTVANHIKE------------------------------------NG-PY---DG-IVGFSQGAALSTIITNKISELVPS------------------------------------HPEFKVSLVISGYSFTEPDPEN--------------------------------------------------------------PGQLRIT--------EKYRESFKP----NPESQTKMLF--VYGAS---DMAVPSERSKYL----YNL------YKESFGEDAEGTKLHAFEHPGG-----HMVPNK-KDI-----IRPIVEQITSSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
chagb-q2h3l0   	--------------------------------------------------------------------------------------------------------------------------------------------------------------MSEPTPEPIQ----------------------SAPP-----GKAGTRP-----PTSKNTASLKKFRILMLH------GYTQSGPSFATK-TSALKKVLNTALKPHGL---ESV-----LIYPTAPNKLS-PLELPSPDEED--------------------------------------------KPDPEWYAWVPQGRPH-----------------------------------GRVPASRQGHEPHRPTHCE-RRGGRRVLRY----RDRREEGR--------TVCVQKG-LL---HGGVGIFRQPDGQDTIHDVQV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
chagb-q2h9k2   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKILCLH------PWGTSGFIFEKQ-LQTLSGILGP----------THE-----YVYINGGVPSARARDLPD----------------------------------------------FVKGPY---YCWY--EG-L-----------------------------SS-------PQCQEAHDTITETIKE------------------------------------EG-PF---DG-VIGFSQGASLALSFMLHH---ELHN--------------------------------PGLPCPFRFALLFCANLVIS-PDPKFNQ----------------------------------------------------------------------------------------D----KVVK--YSGYY---KASRDGVRPAGE----VGEEHNDEDNDE--------D-NDDQYKTET-----GEGNGT-HQTVQTTPATPATPLAPDASSSKRRAAPKHRA----LLLLPGRKKALVEEL-------VDLID-EASHNLSGEAD--ASKHSWPEDPKPEDFPRLMH------------------------PLT---VKAR------------------VPIPTVHVIAQNDPLM--RHTELAVRLCDKKKTKLVYFDGPHRI------PTAPSTLNAIARAVEWAMQKGQLM-------------------------------     =====>
cloab-q97fl1   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRKSSK-----------------------IKRIVLAVVLVIFIFANCVGLYVGNLIYDKV-CKMQFDRSQSSY------NN-FK-----STFNYERYNLLNKSDVVI-ESNFGYKLSGTYIKNFVDSRKTIIIVHGITGSRWESMKYA-----DIYLDLGY--NVLIYDSRYHGVSGGNDITL----------------------GYFEKYDLNNCVK--------------------------------------WVKNKTPG-GI---IG-IHGESMGAATALLQSNMNEKTK----------------------------------------DVSFYVVDCPFSDLPQLFGEKL--------------NY---EMKNHGAVVAKMVV--------------------------FYSSLIAFFKAGFSVYAISPIKA------IQDVKTPIMF--AHGAD---DDLIPPEMSVDL----YSI------KKG----------AKYLYIAPNAGHAEAYLKNK-TDY-----TNKVRQFLIDIHVEDNKTDINKPVR---MY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
cryne-q55ws3   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTIRILTLC------GFTQNSHIYSKQ-IGAVRKA---VK------NA--E-----FVFVDPPIVVQK--------ADLP-----------------WITPANLDQFGS-SASMDAETQTAETT--PR--AWWLNSDEW-KTFRR----------------------------------FDETVAYLHD------------------------------------YIVKNG-PF---DG-VMGFSQGAGMAALLAAMVEKPGIHPN----------------------------FPAEPPIPKFKFAIFVGGFLPGYRPK----------------------------------------------------------------------------IESHDFTNYF------PLPSSLVTLH--ISGRN---DTLITPERSEIL----MKH------CEN----------ARFELHDGG-----HYTPSK-ASW-----RHFLNAYINSFAPGGSNGDL-PSVD---SY-GP----NGP--------------N-----APPTGK---GG-KSGTNTPKSKSGANTP--KVDPE---------------TEEPQTESKSV------AALSS------------------------------------------------------------------------------------------------------------------     =====>
cryne-q5kjh3   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRVLCFC------GFTGNKYIFAQE-LSRLRAL---CA------DS-VE-----FVILEPPMIVHP--------VDFP-----------------LEFQAARESTGW------TIERTVETT--PR--AWFDGGADW-HGDRG----------------------------------FTDSVAYVHK------------------------------------FLTENE-PF---DG-FLAFSSGATLAFVVVALLMKGAQHSDR--Y------------------------FPFHPRLQKPRFFINTSGFFIGGHST-----------------------------------------------------------------------------PHPSYAPLF------PLPASFPTLH--VIGKN---DTIVPHVETEFM----TKM------CLN----------KRVEWHMGD-----HFVPMK-ASW-----RGFFKDYIESFLPGGADGEGIPHPN---EF-SP----SVI--------------S-----QLR----------SVRIQSQLDSGFMLP--SVAHV---------------SAEKGLNQNSRVRLVI-APLQVKTVGVPVYVLNQGVV---------------------------------------------------------------------------------------------------     =====>
cryne-q5kjh4   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTIRILTLC------GFTQNSHIYSKQ-IGAVRKA---VK------NA--E-----FVFVDPPIVVQK--------ADLP-----------------WITPANLDQFGS-SASMDAETQTAETT--PR--AWWLNSDEW-KTFRR----------------------------------FDETVAYLHD------------------------------------YIVKNG-PF---DG-VMGFSQGAGMAALLAAMVEKPGIHPN----------------------------FPAEPPIPKFKFAIFVGGFLPGYRPK----------------------------------------------------------------------------IESHDFTNYF------PLPSSLVTLH--ISGRN---DTLITPERSEIL----MKH------CEN----------ARFELHDGG-----HYTPSK-ASW-----RHFLNAYINSFAPGGSNGDL-PSVD---SY-GP----NGP--------------N-----APPTGK---GG-KSGTNTPKSKSGANTP--KVDPE---------------TEEPQTESKSV------AALSS------------------------------------------------------------------------------------------------------------------     =====>
danre-OVCA2    	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAVPLRILCIH------GYRQNGNSFREK-TGALRKLLKK----------QVE-----LVFISAPHQVPAIQEENC-----GTNQQSQ----------------------------------TVSVGDEDQRGWWFSDVQ------------A-RSF-------------NAKQDCESSLGLEESIEAVKAALKD------------------------------------LG-PF---SG-ILGFSQGAALVAMLCALQEQKL-----------------------------------EPDFNF-RFAILVAGFRSACLE--HQRFYE-------------------------------------------------------------------------------------GPVITIPSLH--VFGQD---DRVIPEEMSRDL----LPA------FD---------G-AQVLLHPGG-----HFVPAA-SSH-----RQTYQDFLKRFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
debha-q6bhb8   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPKNEIKFKGKILFLH------GYTQSSSVFYAK-TSALRKKLLKL---------NYK-----SVYLNGPTKLT-PADLPSTDSLSK----------------------------FNTVI--------SDDEETNYRSWWIKPHNT-----------------------------------NDGIDLSEPLAEIKNYIDK----GEIIPDN-----DLVQETE--------SDEERRL-PI---VG-IIGFSQGAALAGLLSHKFKDLFGV-------------------------------------DSLKFVILYSGFKIDTSEKSG--------------------------------------------------------------------N--------AKYKDYYPADNG--ESDQFKVLH--IYGEL---DTVVHEDRVLSL----YEI------TKD---------NSDILKHPGG-----HFVPNS-KLM-----VDQTTNWIVHIMENK-QEISKPED-------------------------------------------------------DLDSLMDM--------MDGL-----------GKA-------------------------------------------------------------------------------------------------------------------------------------     =====>
debha-q6bmh3   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVTKKILCLP------GYLQSGKVFAEK-SSGLRKLLTKK-----L---NLQ-----LDYVNPPFVIKNKEDLPFILAEEVEDAD----------------------QKW-----------KSIIDQNCNRCWWQHQD---P---------------------------------NVYEGFDESLKFLVEYIKT------------------------------------NG-PY---DG-IIGFSQGAAMSAIVTNVISELLPN------------------------------------HKNFQIAVFFSGFAFTEPVDPSKDNK-L------------------NLNYHIDDIN--------------------------EYKTKVKII--------NSYERYYND----M-HSNTKILN--IYGSK---DMTVPGIRSQYL----STT------FKN--------ENLTEYIHEGG-----HFIPNK-KQF-----LSPIIEDFREIFDIRSNL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
dicdi-P90528   	MTILGLISSISNVKSISKSNNLSSLSNSLSSLQSMNSIERRGGISISNPGFLGGIGRNPGESMVCDSGGKMTKSSLSVSQNGKEKESNGKSLNKSSSSSSSNSLNKSTENTNSSSSSSSGSGSPNTTTTTTTTTTTSTANQQQQQQQQQQQQQQQ---------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ--------------QQEQQEQEHEQQQSNPS---LF------N---FGAHYDSL-CNMIIRPPRYTYSLDDLGPKAFSLGHPLKTYVRNDFELINPRGHSIQCSHF--KQS--EYWETGEKQPCVIYCHGNSGCRLDAMECVR-------TLLPMNITVLVFDFSGSGLSGGQYVSL----------------------GYFEKEDVGVIVKHLRD--------------------------------------TGKI-ST---IG-LWGRSMGAVTSILYARD-------------------------------------------DPSIAGMVLDSPFSSLYKVAEELVHSAVQK-------LPK---LMISLGLKMVR-------------------------------GS--IKKRAHFDIKELDVLNI------ADQVYIPALF--AHGES---DNFVRPHHSEKL----FEK------YNG----------DKNRLLLKGGHNSE----RP-NFF-----LESVCIFFQNTLKP-NQDDSNDSND---PK-GP----EMT---------IHELFR-----NPELLF---DD-CSVEEQKM---LFVLY--QQQQQKKKQQQQQQQQQQQQQQQQQQQQQQQTSTSL-PPP--SEIQSPHLIVTEPSIYSSKGNGPLPPPA--------SNPTPQQLQ-----------------QNDFSFVQNSLE----NNNNINN---NNNTDNFNNEN----I--K-------     =====>
dicdi-q55d01   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAIGVETPKKLLRILCLH------GYKQNAVAFRSK-TAVLRKSLKD----------IAE-----FIYVDAPHMVDES---------------------------------------------------------KGSSSWWRASKD-----------------------------------GKEYRGWEQTLDYLRNVFET------------------------------------QG-PF---DG-VIGFSQGAVLASLICSISSLNNDNY-------------------------NYNEDSNNSCF-QIKFALLFSGFQSRATA--HQSLYPQSSPPPSSSAISTTLKNGENSGCECCSVTQFEMEHTTTTPSSSSSSHQHQQQHSPPSPTSLSLTSS---TSTTPTTSFYP-----LAKINTPSLH--VWGKA---DELVAASNCESL----SHQ------FS---------N-PECYVHEFG-----HLIPTS-KTD-----IQIYHNFLAKFLKDCGLE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
drome-CG5412   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTNNDAAVEAAGSSR------ASSSKQQLKLEITEKVRVLCLH------GYRQNGEAFKNK-LGSFRKFANK----------YAE-----FVFITAPHVAKALES--------------------------------------------------AAEPVPEQRSWWANKDD--------------GSF-------------KGTNKGGPAFGFQESLRCVEEAWRT------------------------------------QG-PF---QG-LLGFSQGACFVGLICGLAKKKL------------------------------------TSI-RPEFAVLASGFLSGSLV--HMSAYE-------------------------------------------------------------------------------------EAI-SIPTLH--IYGQT---DEIIPKEMSESL----AAR------FK---------N-AEVLEHSGG-----HYFPAT-AQQ-----KQTFINFFQDRLQEYLEHEELQQSGNASFVD-------------------------------SGAEDDNDA----E---------------VAAMT---------------AELDE---SD-----------------------------------------------------------------------------------------------------------------------------     =====>
drops-q29br3   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTNNDAAVEAPSSSR------ASSSKQQPKLEITEKVRVLCLH------GYRQDGDAFKNK-LGSFRKFTSK----------YAE-----FVFISAPHIAAPLES--------------------------------------------------AAEPVPEQRSWWANKDD--------------GTF-------------KGTNKGGPAFGFQDSLRLVEEAWKT------------------------------------QG-PF---QG-LLGFSQGACFVGLICGLAKKKL------------------------------------TSI-RPEFAVLSSGFVSGSLV--HMSAYE-------------------------------------------------------------------------------------EPV-SIPTLH--IYGSS---DEIIPKDMSALL----ASH------FK---------N-VEVLEHGGG-----HYFPAT-AQQ-----KQTYINFFQDRLQEYLEHLELQQSSSVSFIE-------------------------------SGAEDNDDD----GD---AND------AEVAAATAAA-----------GSDLDD---SD-----------------------------------------------------------------------------------------------------------------------------     =====>
emeni-q5ar63   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEKANILCLH------GYGTSASILQHQ-LGPFMAAADP----------SYE-----FVFLEGEIECQKAQGLGP----------------------------------------------FVKGPF---LCYN--ES-F-----------------------------AP-------ADIQESCDLIDEMIQA------------------------------------AG-PF---DG-IIGFSQGGSVALSYLLQR---QI----------------------------------DGHPPPFRWAVFFSTVIAFA-P------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
emeni-q5arw5   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FDFISGPFPSSPAPGIKA----------------------------------------I-----YPDSPT---YTWF--RE-P-----------------------------TP-------AGLRAAHRYVAEYIQK------------------------------------HG-PY---DA-VMGFSQGCSLIASMALYH---SYDR------------------------LSEQGQNGIRGDLPFKAAIFICGGIPLYALQ--------------------------------------------------------------------------------------------------------DMGIP---VS--------EE----AET-------------------------------------------------------ISKITGQ---------------------LLNTTATK-------LSTFASNT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
emeni-q5b3v4   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGRPPLKLLMLH------GYTQSGPLFHAK-SRALIKHITKAFPLH-----EIS-----AIYPTGPLRLN-PADIPGYTPAHDSNGN------------------------------G-----DDKDTEIEAYGWYRRSNTAEP---------------------------------PLYVGLEDGLNAIAKVLGE------------------------------------EG-PF---DG-VIGFSQGAAMAAMVASLLEGEKRREAFARFASSSCSS-----SETTAEGIPYPDSFAELDHPAMKFVLCYRLFMRLRRF----------------------------------------------------------------------------------RRLSCMC-----WALWMRLLMRGGVGRLWKLALGIRRARARLFGILGVTF------CRAS---------GLI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
emeni-q5b7i6   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRILFFH------GHTQTGPVFERK-TVRLREHIQRAYPGS-------T-----FFFPTGPIAYK-VSDRLDYLSEIQRERS-----------------------------DN-----FKDPDLIETHAWFRLFEDDPP------------------------------------RGLLESLDIAAEILRV------------------------------------EG-PF---DG-VICFSQGSVVGSMMASLLEGPRRRQRFDEYAAS------------FPGAVRYPKSYKNINHPPLKFGITYGAYMGTSPV----------------------------------------------------------------------------------FNAFYSE-----PLIETPFLHF--MGEF---DPVVPSEMVAAVD---KA---------QI-----GGSRRRKVMHPGA-----HAIPVG-DRY-----HEAVVDFIRSACETSPTYFD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
emeni-q5bg01   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVG--------------------ADRSVTLHLPRILCLH------GGGTNANIFRMQ-CRVLARM---LQ------PY-FR-----LVFAEAPLAALP--------G---------------------------------------SDVTAAYKDYGPFKAWLRVRDE------------------------------------DPVLDAHHIVSKIEDSLKAARIT--------------------------DDCRGATG-EW---VG-LLGFSQGAHLAASILANQQELGRR------------------------------AGDDAARPVYRFGVLLAGRGPLRWLHPDLPIPPGFV--------DV---SKCTTGME---------------------------------------------REYEPFVNSS------PYRLQIPTIH--VHGLA---DPNIELHR-KLH----DQY------CDP----------RSTILLEWG---GDHRVPIK-ARD-----VTPIVQQIIAVARQEGVL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
gibze-q4hww3   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLLCLH------GRGTNSDILESQ-LAPLVSRLSE----------RYT-----LDFLDGPCQVNAAPGVDS----------------------------------------------RSSGPF---LAWH--RR-H-----------------------------FA-------KDVASAYAYVQAVITE------------------------------------DG-PY---DG-VIGFSQGAALAVGLLISH---QHQA--------------------------------PTGVNLFKFAILFSSVLPTA-PSGEIGV----------------------------------------------------------------------------------------D----CTQY--VVDYE---KSLP-------E-----------------------------------------------------------------------------------------------------------FFG-LSSSEIADTAS-AERAYLF------------------NHLAGD------------NKPNE---TRHT------------------VDIPTLHVLGRKDPFF--DFGKAVIELCDSKKREVILHDGGHDV------PRSQDCIGKIALLMETVAELSKIDF------------------------------     =====>
gibze-q4i027   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTATPTTKANGNGGKKEVKILMLH------GFTQSGELFRAK-TRALEKTIVKLLNPISL---LPV-----FLYATGPSRLS-PEDIPGYQPPEE----------------------------------P-----QAEDYQPDTWAWWRKDEAS-----------------------------------GNYRLLDEGMATVAQAIR------------------------------------DSE-GI---DA-VCGFSQGAAMAALVAAAMEPD-----RAVPEG---------KEGNWARG-----LREANSGNPLKFAVCYSGFWATPDS----------------------------------------------------------------------------------LQFCFG------PKIKTPTLH--FVGSL---DTVVDEDRSRAL----SDR------CED----------PLVLIHPGG-----HHVPVN-KQW-----AAPLAGFIKEHGQDKEPKAEL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
human-OVCA2    	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAQRPLRVLCLA------GFRQSERGFREK-TGALRKALRG----------RAE-----LVCLSGPHPVPDPPGPEGARS-------DF----------------------------------GSCPPEEQPRGWWFSEQE------------A-DVF-------------SALEEPAVCRGLEESLGMVAQALNR------------------------------------LG-PF---DG-LLGFSQGAALAALVCALGQAGD------------------------------------PRFPLPRFILLVSGFCPRGIG-FKESILQ-------------------------------------------------------------------------------------RPL-SLPSLH--VFGDT---DKVIPSQESVQL----ASQ------FP---------G-AITLTHSGG-----HFIPAA-APQ-----RQAYLKFLDQFAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
klula-q6ctp8   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTTATAAPKLLFLQ------GFLQNGKVFSEK-SSGIRKLL-KK-----S---NVQ-----CDYMDAPVILE-KKDLPFEM------DD----------------------AKW-----------QETLNAGVNRAWFYHSD---I---------------------------------SSELDLSPAIEAVTKYIKD------------------------------------NG-PY---DG-IVGFSQGAALASIITNKITELVPS------------------------------------HPQFKVSLLIAAYSFTEPDPEN--------------------------------------------------------------EGQLRIS--------QKFQDSFKP----MDDRTTKMLF--VYGTA---DMAVPCERAKYL----YNI------YTKGQEL----DDCKAYEHPGG-----HMVPNK-KDI-----IRPIVEEINTSLGVSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
klula-q6cu78   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTSKKVLMLH------GYSQSDVIFRAK-TAGMRKQLQKK---------GYE-----LIYPCGPYKLH-SKDFNDSEVDL-----------------------------------------RDSEKSTGMYGWFLKDPET-----------------------------------HSYTLEPELLEYLAQYIKE------------------------------------NG-PF---DG-IGGFSQGAGLAGYLSTDLWSILPL--------------------------------NKEEQPPFKFAMYFSGFKFEPEQ----------------------------------------------------------------------------------FQAPYET-----HPIQLKTLH--IVGEL---DSLVTEERSMKL----FEA------CDP--------STRTMVKHSGG-----HYIPNT-KPF-----INMILSWLHAQADENLRELSGSEE---SAM--KNT-------------------------------------VNNSDPQLDDDLLDM--------IDSF-----------GKI-------------------------------------------------------------------------------------------------------------------------------------     =====>
klula-q6cu79   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKKVLMLH------GLAQSGPYFESK-TKGFRRVLEPL---------GYE-----FFYPTAPINLS-PADLPSDVADI------------------------------------------GAASGDDYHAWLQPDPLH-----------------------------------GEYRLPDVTLKFLKEYVVE------------------------------------NG-PF---DG-ICGFSQGAGVTGYLMTDFNNLLGL--------------------------------TEEQQPAIKFFIAFSGFRFRPEI----------------------------------------------------------------------------------YQEQYIQ-----HPITVRSLH--VQGQL---DTVTESSQVKGL----YTS------CKE--------GTSTFLEHSGG-----HFVPNS-KGF-----VLKIADWLQNSE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
maggr-q2kgk9   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSANE-H------HTEQA-----NRPQAAP--QSRPQAAKKPAKKEIKILMLH------GYTQSGPLFHAK-TRALEKLMIKSLAPFNL---QPT-----LIYPTAPNQLR-SVDIPGCNPVAG-------------------------------QDDP---------RATDSWSWFRMFDAT-----------------------------------GAYRLLREGMSRLTEAVR------------------------------------DAG-GV---DG-VIGFSQGAVMASMMTGVLDEPRREVP---GSD---------SAKQWVAE-----LREANGGRALKFAVFYSGFAAKPPG----------------------------------------------------------------------------------LGWMYE------PSINTPTMH--FIGSL---DTVVDEKRSRDL----AEK------CVN----------SIVIEHPGG-----HHVPTG-KEH-----AMPLIGFIKQNAW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
maggr-q2khg5   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSRMRILALH------GMGCSAKILRAQ-LSAFIRAVDD----------YY----------------------------------------------------------------------------------E--IG-Y-----------------------------AP-------SDILESHKCLRKVISK------------------------------------HG-PF---DG-VLGFSQGGAIALAYLYHQ---QQ----------------------------------DGFTPDFKFAIFLSTIVPFS-ADCRTLE----------------------------------------------------------------------------------------K----AAQH--LCDPL---RN------PLPR------ESHQH------------------------------------------------------------RLASELRD----VLL--------------------HIF--TVSCSIGATAAGYDNNYFFRPGADPAEVPRPLHPRLICLADDA------------KTPAD---LNTR------------------LAIPTVHAHGRRDFVYMRESAEAVRELCEPRLARFLMHSGGHSP------PQRPDEVAALAQAVHRAVRQYYEIAHL----------------------------     =====>
medtr-q1sd74   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGENGRKLKILCLH------GFRTSGSFIKKQ-ISKWDPS---IF------SQ-FH-----LEFPDGKFPAGG--------K---------------------------------------SDIEGIFP--PPYFEWFQFDKDF-TVYTN----------------------------------LDECISYLTE------------------------------------YIIANG-PF---DG-FLGFSQGATLSALLIGYQAQGKL----------------------------------LKEHPPIKFLVSISGSKF---------------------------------------------------------------------------------RDPSICDVAY------KDPIKAKSVH--FIGEK---DWLKIPS--EEL----ASA------FDK----------PLIIRHPQG-----HTVPRLDEVS-----TGQLQNFVAEILSQPKVGVSICEHE---SK-VE---------------------------V-DGTN---GD-KGVNGVEINQGNAETV--EVVQ---------------------------------A----------------------------------------------------------------------------------------------------------------------     =====>
mouse-OVCA2    	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAARQTLRVLCLA------GFRQSERGFREK-TGALRKTLRG----------RAE-----LVCLSGPHPVPEAAAPEGSCP-------DS----------------------------------GPCSPEEQPRGWWFSEEE------------A-DVF-------------SALEESTVCRGLQEALETVARALDT------------------------------------LG-PF---DG-LLGFSQGAALAAYVCALGQAGD------------------------------------PRFPLPRFIILVSGFCPRG---LKEPILQ-------------------------------------------------------------------------------------SPM-SLPSLH--VFGDT---DRVIPSQESMQL----ASR------FL---------G-AVTLTHSGG-----HFIPAA-ASQ-----RQAYLKFLDQFAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
neucr-q7s2e5   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRFLCLP------GAYGSSDKFQVQ-LAPIVKELTED-----G---TAT-----FHFIHGPCKAVPPEGFEA----------------------------------------Y-----FGKPPY---YRFIEPDRDVEKT-QDDDVLARIRDFPNCESPEDTMRELMSEGVATSHRSTDNALKYLIRIMDE------------------------------------RG-PF---DA-IIGYSEGAAVAATLLLHEQR-RFKK--------------------------------KGIKPMVKYAIFFAGWPPVD-PDTHQMILS-----------------------------------------------------------------------------DES-----DVVIEIPTCH--ISE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
neucr-q7sgj0   	---------------------------------------------------------------------------------------------------------------------MADSAQPT-----------PVQ-----------------SSASTPAPSDISNAN-----VPAQQKQ------QKQQN-----NKKQNRPPHPNAANAKPKPVKREVRILMLH------GYTQSGPLFRAK-TRALEKLLIKALSPLNL---VPT-----LIYPTAPNRLS-VSDIPGYEPSTS-------------------------------DSGP-----GGDKELSDSWAWFRREEAT-----------------------------------WNYKLINEGFERLAETMRGVNLEGREVVDGLVTDSKVDGEGKEAEERKEMKGVVRSE-VI---DG-VIGFSQGAAMAAMLTAAMEHLAPGQPRPVLTP---------DHEGWVKQ-----IREANKGQPLKFCVSYSGFFALPPE----------------------------------------------------------------------------------LGWLWE------PKVKTPTLH--VLGSL---DTVVEESRSRRL----IEA------CED----------PVVVVHPGG-----HYVPVN-KEW-----VAPLVGFIRTCLEKHQQKTEEEGEK--KKVEES--------------------------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
orysa-OJ1200.C0	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MELDKKFKVLCLH------GFRTSGSFLKKQ-ISKWNPS---IF------QQ-FD-----MVFPDGIFPAGG--------K---------------------------------------SEIEGIFP--PPYFEWFQFNKDF-TEYTN----------------------------------LDECISYLCD------------------------------------YMVKNG-PF---DG-LLGFSQGATLSALLIGYQAQGKV----------------------------------LNDHPPIKFMVSIAGSKF---------------------------------------------------------------------------------RDPSICNVAY------KDPIKVKSVH--FIGEK---DWLKVPS--EEL----AAA------FED----------PVIIRHPQG-----HTVPRLDEAS-----VKQLSEWSSSILEDIKNADDVAKAS----I-VE---------------------------K-P-----------SEGNTVAESGENLV--EQIA---------------------------------A----------------------------------------------------------------------------------------------------------------------     =====>
orysa-q2qnj4   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKKLKILCLH------GFRQNASNFKGR-TSALAKKLKH----------IAD-----LVFIDAPHELSFVYKPNPDHCSGR----SS----------------------------------LPSGTPKRKYAWLVAPNSIFYA-EHDWKIAD-APF-------------DPLQYQQQTDGFEESYAYLEHAISQ------------------------------------MG-NI---DG-ILGFSQGAAMAALFCRQQQKTC------------------------------------GSL-KFRFGIFCSGYP-APII----SDFD-------------------------------------------------------------------------------------GEPIKLPSLH--CFGNSEDHDRQIANRASTEL----ANR------FDK--------SCRSVIEHDMG-----HIIPTR-PPF-----IDKIKEFLSNFI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
orysa-q7xv53   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSLGG--------------EEGARPAAAAEGARRPRFLCLH------GFRTSGEIMRKQVVGKWPAD---VT------AR-LD-----LVFADAPFPAEG--------K---------------------------------------SDVEGIFD--PPYYEWFQFDKNF-TEYRN----------------------------------FDECLNYIEE------------------------------------LMIKEG-PF---DG-LMGF