MSA from Cobalt (Ncbi)
Cobalt
Color code Main amino-acide (aa) at this position Non majority aa at this position 50% conservation Catalytic site Catalytic site in alignement
Position ....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....790..5....800..5....810..5....820..5....830..5....840..5....850..5....860..5....870..5....880..5....890..5....900..5....910..5....920..5....930..5....940..5....950..5....960..5....970..5....980..5....990..5....1000.5....1010.5....1020.5....1030.5....1040.5....1050.5....1060.5....1070.5....1080.5....1090.5....1100.5....1110.5....1120.5....1130.5....1140.5....1150.5....1160.5....1170.5....1180.5....1190.5....1200.5....1210.5....1220.5....1230.5....1240.5....1250.5....1260.5....1270.5....1280.5....1290.5....1300.5....1310.5....1320.5....1330.5....1340.5....1350.5....1360.5....1370.5....1380.5....1390.5....1400.5....1410.5....1420.5....1430.5....1440.5....1450.5....1460.5....1470.5....1480.5....1490.5....
9acto-q3w9q0 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG---DRRFVRSAAPLTL-------------ERGG--------SL-PEVTIAYETWGTL------------------APDA----GNAVLVLHALTGDSHAAGGAGP-------------GHPTPGWWGGLVG-PGA-VLDTDRFFVVCPNVLGGCQG------TTGPASA-ASD-------------G---------------RPWGGRWPE---------------ITVGDQVR-----------------AEALLA-DELGVGRWAA--VIGGSMGGMRALEWALAFP----AR-----------VRRAVVIACGAT----AT--AEQ---IAL-YATQLAMIRADPNWH--GGDYHDRP-------PGAGPHVGLGLARQMGQVSYRSERELAHRFGNAVQ----------------------------------------------------------------------------------------------------------------------------------------------A---DGRYAAASYV--------EHHGAKLAH--RF----------------DAGS-------------YLTLTAAMMSQDAGRGRGGV--------------------------------------------------------------------------------PAAL-RACPVPVTVAGIDSDRLYPPRLQAELARH-----L--GT-----------E---LRLVPSASG-HDGFLL-----ET-AA--VGQIVRDALTPAATGPRTPSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9alte-a6f1y1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDPLPTDSVGIVTPQ-----TLHFD-TPITL-------------ACSQ--------TL-ESYDLVIETYGKL------------------NADA----TNAVLICHALSGHHHAAGYHSK-----EDR--------KPGWWDSCIG-PGK-PIDTNRFFVVSLNNLGGCHG------STGPGSI-NPK-------------------------T--GQPYGPDFPV---------------ITVRDWVH-----------------SQALLA-DRLGIECWAA--VVGGSLGGMQALQWSLDYP----DR-----------LRHAVTIASTPR----LS--AQN---IAF-NEVARQAITSDREFH--DGRYYEH---------DTLPRRGLMLARMVGHITYLSDASMGEKFGRELRDQA---------------------------------------------------------------------------------------------------------------------------------------YKFGY---DAEFQVESYL--------RYQGERFSE--SF----------------DANT-------------YLLMTKALDYFDPAYEH-DND------------------------------------------------------------------------------LAKALLR-ARCEFLVVSFSTDWRFTPARSEELVNA-----MIAAR--------R---KVSYAEIDAPWG-HDAFLI-----PT-PRY--TAIFHSYMDRVAREVGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9baci-q2ayr6 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M----QI---VKKEKFVLKEFVF-------------ENGR--------EI-P-VQMGYETYGTL------------------NRER----SNAILVCHYFSATSHAAGKYTE-------------HDEEAGWWDGLIG-PGK-AIDTNKYFVICTDNLCNVQVKNPYVITTGPKSI-NPMT------------G---------------FEYAMDFPV---------------FTFLDVAR-----------------MQYELI-KDMGIARLHA--VMGPSAGGMIAQQWAVHYP----HM-----------VERVIGVITNPQ----NP--IIT---SGNVAQNAIEAIQLDPNWK--GGKY-----------GEEQPTKGLHLANRMMFMNAFDEHFYETAFPRNSI--EM--------------------------------------------------------------------------------------------------------------------------------------APYQEF--SALTSFEKEI--------NKVTCKSID--LV----------------DANS-------------WMYTAKAVLLHDIAHGFSSL--------------------------------------------------------------------------------EEAL-SNIEANVLMIPCKQDLLQPPRYNYKMVDI-----LQKQG-----K-Y--AE---VYEIESING-HMAGAL-----DV-HL--FEKKVYEFLNRKVSSFV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9baci-q2bd09 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDYEIYNLGDVTL-------------QSGV--------TL-PNAFLAYKTYGEL------------------NEKK----DNVIVYPTAFGDQHVQ-NE-------------------------WLIG-EGM-ALDPRKYFIIVPNLLGNGLS------SSPSNTP-A----------------------------P---FDRSSFPQ---------------VTIYDNVT-----------------LQHRLVTEKFGIQKIAL--VLGWSMGGLQSYQWGASYP----DM-----------VERIAPFCGSAK----TW--PHT---FMV-LDGMKASLMAAVGFD--SSK------------------------------LNELTSAEMRAAGHVYG-----------------------------------------------------------GWGLS----------------------------------------------------------------------------------QAYYREALYREM-----GFDSLEDFIA--GV-------WEDSFMK-MDPHN-------------VLAMLWTGQYADISANPA-----------------------------------------------------------------------------YNGDFDLAL-RSIKALACVMPGSTDLFCTAADNKYEASL-----LP------------NAV---YKPIESMWG-HFAGRGINS-RDN-KF--IDDNLKSLLSLGKE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
9bact-a6dp85 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLVKEQ--FFSFASKE-EPFRL-------------RCGK--------NL-NEVQVCYESYGEL------------------NAEK----SNAILICHALTGSAHVAGRHSE-----DDR--------KPGWWDEMVG-PGK-SFDTNKYFIVCSNILSSCYG------TTGPQST-SPE-------------------------T--GESYNLDFPM---------------TTIYDMVN-----------------VQNELM-KHLDVEKWLA--VAGGSLGGMQALQWAVTYP----EK-----------VHSCIPIATAAQ----CS--PLS---IGF-NWVGRESIIKDENFD--DGNYPKG---------T-QPEKGLSIARMIAHMTYLSDVSMQNKFGRKLQEMD--------------------------------------------------------------------------------------------------------------------------------------DVNY-EF--THNFQVESYL--------NYQGRQFVN--RF----------------DANS-------------YLYITRAMDYFNLAEEGEDKS------------------------------------------------------------------------------LAQALAK-SLCQFCIISFSSDWLFPPYQSVEIVNA-----LAENH--------R---TATYCNIKSDAG-HDAFLL-----EV-DVL--APIIGNFLEQQLESCSNA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9bact-q26g67 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS---ASLYHIELPGF-K-------------LSYG--------KV-QTVHVSYQIFGRQ------------------L--H---TAPIVLVNHALTGNSSV-----------------------MDWWSEIVG-SNK-AVDTNRYTIIVIDIPGNGFD------ENVEHL-------------------------------------IYNYQD---------------WQLSDVAR-----------------VFQLVL-SELRICYVHV--GIGGSIGGCLLWEMVVAYP----EL-----------FGTIIPIAADWK----AT--DWI---IAN-CHIQERLLKHS--------------------------SNPLEDARQHAMTLYRTPQSLRYKFNRELDT---------------------------------------------------------------------------------------------------------------------------------------------------EFKVKQWL--------NHHGVALKK--RF------------TL-PAYKL----------------VNHLLATANAARKYE-------------------------------------------------------------------------------ENILKAL-SNSNVKIRVVAINSDGFFTAQEDRETVKL-----LSR--------Y-INIT---YQEIDSIHG-HDAFLI-----EH-YQ--VRKLLENYLAEVESKAPLKE-----------------------------CV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9brad-a3wrp6 -------------------------------------------------------------------------------------------------------------MSRPACSHVKQLAKQAGDSEI-----------LIPAEPKFGP-------GFLWPA------IRRLLQPP-AEVSG----RMVKVQS------------------VSS-PVQAEYRAQEADHPTS--QVATFGSD-HPLPL-------------DCGI--------DL-APFQIAYQTYGEL------------------NTAK----SNAILICHALTGDQHVANHHPV--------------TGKPGWWVTLVG-PGK-PLDTSKYFIICSNVIGGCMG------STGPASI-NPA-------------------------T--GKVWGLDFPV---------------ITIPDMVR-----------------AQAMLI-DRLGIDTLFS--VVGGSMGGMQVLQWCVAYP----ER-----------VFSALPIACSTR----HS--AQN---IAF-HELGRQAVMADPDWR--EGRYVEQ---------GTHPHRGLGVARMAAHITYLSDAALHRKFGRRMQDRELP--------------------------------------------------------------------------------------------------------------------------------------TF-SF--DADFQVESYL--------RHQGSSFVE--RF----------------DANS-------------YLYLTRAMDYFDVAADH-NGV------------------------------------------------------------------------------LAAAFRD-THTRFCVVSFTSDWLFPTSESRATVHA-----LNAGG--------A---RVSFAEIETDRG-HDAFLL-----DV-PEF--FDIARAFLESAGKTRGLADAGQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9brad-q35cx5 MKSSPSSSASTASSTTSRITWACVASAPSAPRVTSPKVSRPNSSAVVMSRSIPSCRHTASRCQLEGVEPDCKPAVAKH--RVSPSRRQLVSHSPRDRARIPPSWPGL---SRPSTSPGD-----ADGRGCPGHIVEGVPSCNTRAQPTAGTR-AHGDAKRFVPAMAAVPTMRSCHAKKWACEPAAHHLGLLQLLHG--TA------------------------RM---T-SV---ADYQIFEAGDVVL-------------QSGA--------TV-PSLRLAYKTYGTL------------------NAAK----DNVILYPTSFSAQHVD-TE-------------------------WLVG-PAD-ILDSDRYFIIIPNLFGNGLS------SSPSNTP-P----------------------------A-----DAPFPA---------------ISYHDAVA-----------------IQRRLVEEQFGITRIAL--VYGWSMGGMQAYHWAACHP----DM-----------VERAAVVCGSAR----CS--PYN---HVF-LDAVKAALIADPAYK--NGR------------------------------FVAKPVAGLRAMGRIYA-----------------------------------------------------------GWAMS----------------------------------------------------------------------------------YEFYRDEVWREQ-----GFAAQEDYLA--AT-------WDTAFAH-RDANN-------------LLAQIAIWQNGDISHCSA-----------------------------------------------------------------------------FGGDLDRAL-SAITAHMLLMPGQTDRYFDWRDNERELPK-----LVN---------ASSAV---LRPIPSIHG-HRAGNPIRIPADR-DF--IKANILTLLQS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9burk-a6gmv8 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSANQSVGFVKPE-----LIEFT-APLLL-------------ECGK--------SL-PSYSLMVETYGTL------------------NAEK----SNAVLVCHALNASHHVAGLYEG-----QEK--------SEGWWDNMVG-PGK-PLDTNRFFVIGVNNLGSCFG------STGPSSI-NPQ-------------------------T--GKPYGADFPF---------------VTVQDWVN-----------------AQVRLA-DYFGIEKFAA--VMGGSLGGMQALQWSLSYP----DR-----------VGHCMVVASTPK----LS--AQN---IAF-NEVARQAIVTDPDFH--GGNYYEH---------GVVPKRGLRLARMIGHITYLSGDDMAEKFGRTLR-----N--------------------------------------------------------------------------------------------------------------------------------G--DYNY-GL--EVDFQVESYL--------RYQGDKFAD--YF----------------DANT-------------YLLITKALDYFDPARHT-GGD------------------------------------------------------------------------------LAKALAA-AKAKFLLVSFTTDWRFAPERTREIVEA-----LMANQ--------R---DVTYAEIDAPHG-HDAFLL-----TD-ERY--HNVVRGYFERIAKELA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9burk-q4av60 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M---EQQARHLIDTFAL-------------QCGT--------TV-RALRLEYAMHGQL------------------NHER----TNAILFPTWFGATHKA-NS-------------------------WIIG-PGR-ALDTEKYCVIVVNALGNGRS------SSPSNHP-D----------------------------L---LHGGRPVP---------------VSLHDNVV-----------------AQADLV-RALGIEKLFA--VIGRSMGAQQAFQWGCLYP----DR-----------TGRIFAFCGTPA----TS--THN---RVL-LEGMATILEAAANSE--DSA-----------------------------------KDALRNAGRVYA-----------------------------------------------------------AWVLS----------------------------------------------------------------------------------HEFFNDGSWKGER--------PMDWVS--RM-------ILPAFLE-FHRHD-------------ILSLIRTWQFADISANAR-----------------------------------------------------------------------------FGGNLKNAL-EAITVPVFLMPISHDLIFPPQDFEECARH-----LP------------NSR---TTVLYSIWG-HRAGAPNSDAADI-AE--LETAIRGFLLHPAGDACLAPGR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9chlb-q3vm89 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MR--AYTGMI-SE---KTAYFDSTEPFKT-------------ELGA--------LL-PSVRVAYRTWGKL------------------NARK----DNVVLVCQALTGSAD-----------------------ADGWWEGMFS-PGG-AFDESEDFIICSNVLGSCYG------TTGPTSL-NPLT------------G---------------RHYGPDFPL---------------ITIRDMVE-----------------VQRLLL-AGLGIDRVKL--AVGASLGGMQVLEWGALYP----DV-----------VQALMPMGASGR----HS--AWC---IAQ-SEAQRQAIYADRDWN--DGWYA----------DGHPPAKGLAAARMMAMCTYRSFENFQARFGREFHH-------------------------------------------------------------------------------------------------------------------------------------------------GTTFKAESYL--------HHQGRKLVE--RF----------------DANT-------------YITLTKAMDMHDLGRGR--------------------------------------------------------------------------------AGYEEVL-RSIQLPVEILSINSDILYPKEEQEELARF-----IP----------K--SS---ILYLDEPYG-HDAFLI-----DV-EK--VSRMVREFLEGRALSAHSAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
9chlb-q4amz5 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M--EYIEVI-SE---KTGFFVSRKSFSL-------------ELGG--------EL-PEVSVAYRTWGSL------------------SRER----NNVILVCHALTGAAD-----------------------ADVWWDGMFG-EGR-GFDPAKDFIICSNVLGSCYG------TTGPLSR-NPHS------------G---------------KPYGPEFPA---------------VTIRDMVK-----------------LQRLLL-DELGIEEIKL--VVGASLGGMQALEWGCMFP----DR-----------VRAIMPMGVSGR----HS--AWC---IAQ-SEAQRQAIAADRDWN--DGWYE----------PGNPPARGLAAARMMAMCTYRSFENFQIRFGREKRD-------------------------------------------------------------------------------------------------------------------------------------------------EVTFQAESYL--------RHQGEKLVS--RF----------------DANT-------------YIVLTRAMDTHDLSRGR--------------------------------------------------------------------------------GEYARVL-ESLTMPVAILSITSDILYPQEEQEELVRH-----IP----------H--AT---IEYLHESYG-HDAFLI-----EV-DK--VSRLVKTFRDEITAKDSSAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
9deio-q4haz1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTALI-S------QPD---------LLPPPAPERCP----------PQ---QTARLFRETPLLL-------------DCGQ--------VV-QDVRVAYHTYGTP-------------------------SDHAILVLHALTGTS-----------------------AVHEWWPDFLG-EGK-PLDPTRDYIVCANVLGGCAG------STGPAEL-PRV-------NGEDPPLTLRDM----------------------------------------AR-----------------VGRALL-EELGVRRVS---VIGASMGGMLAYAWLLECP----DL-----------VDRAVIIGAPAR----HS--PWA---IGL-NTAARNAIRAAPG------------------------GEGLKVARQIAMLSYRSPESFALTQ---SGWGT-------------------------------------------------------------------------------------------------------------------------------------------RR--PGTPDITTYL--------EHQGEKLST--RF------------CE----RS-------------YLALTGAMDRFQPT------DAEL---------------------------------------------------------------------------------RSIRVPVLVVGISSDVLYPPAEVRTYAGL-----L------------PRGQ---YLELQSPHG-HDAFLI-----DP-QG--LPEAAAAFLHGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9delt-q1nm41 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS----EY---------------------------VSRDADDVSIGIVEKK--FYTFAEPPAAPLIL-------------ESGA--------EL-GPVTVAYETYGQL------------------SPGK----DNAVLVLHALTGDCHAAGYYSK-----ADP--------KPGWWENMVG-PGK-GIDTDRYFVISSSILGSCGG------TTGPCST-SPV-------------------------T--GKPYALDFPV---------------VTVGDMVE-----------------VQHRLL-KHLGIEQLLA--VVGGSLGGMQALEWSLRYP----DQ-----------VNGVIALATTMR----HS--ALA---IAF-NEVSRQAIMADPNWK--HGNYYGG---------P-KPATGLAVARMIGHVTYLSDEALRRKFGRRLQGKK--------------------------------------------------------------------------------------------------------------------------------------DFSF-EF--DIDFQVESYL--------RHQGSKFVE--RF----------------DANS-------------FLYVTKASDYFDLGRRDNATS------------------------------------------------------------------------------AVEAFAG-VKSRFLVVSFTSDWLYPTYQSRELVRA-----LKKNR--------A---DVSFCEIKADTG-HDAFLI-----PN-RRL--SALLGSFLASTRDGTWLPVPPPEE--EEGEG-----------QDEANS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9eury-a7u103 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSA-VP---TDHGVASLGEFTF-------------ECGQ--------SV-PDFEVAYETHGEF------------------D--G----DNVVLVCHALTGSQNVARSPEPERD--TETAGAGQAGQARAWWDDVVG-PGK-AIDTTEYYVVCANVPGSCYG------TTGPASE-RPAD------------L-------DLREEPDHDRWGTAFPP---------------VQVEDWAR-----------------AQRRLL-DHLGVGRLRA--VVGGSVGGMNALEWAKRYP----DD-----------VDRVVAIATAGR----LD--AQC---LAL-DAVARRAIRADADWN--GGDYYGD--------DRPDPTEGLAIARQIGHIMYLSKASMERKFGRRSAGRDSLTREDGDLG--------------------------------------------------------------------------------------------------------------------------LPPEPTAGF--FPYREVESYL--------DYQAEGFGD--RF----------------DANS-------------YLYLTRAMDEYDLAAGHGAD--------------------------------------------------------------------------------ADAL-AAFEGETLLLSFTADWHFTVEQSASLADA-----FRESG-----V--P-VA---HHVIDSDHG-HDAFLV-----EP-EH--VGPPVRDFLADGVDGRAVSDEGGDD--GDDPR-------PSSDHAPVHASLFRG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9eury-c1v8n9 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MK---TESDTVELGAFDF-------------ECGA--------EI-PSLEVAYEAYGEF------------------D--G----DNAVLVCHALTGSQNVAG-YGT-----------ETAGQARAWWNDIVG-PGK-AIDTNEYYVVCANVPGSCYG------TTGPASE-SPD----------------------------GEPYGTDFPP---------------VTIGDWTR-----------------AQRRLL-DELGVGRLHA--VVGGSVGGMNALDWVRRYP----DD-----------VRYLLAVATAGR----LD--PQC---LAL-DAIARRSITTDPNWN--GGDYYDS--------E--PPDDGLALARQLGHVMYLSKSSMERKFGRRAAGRDARR-----DS--------------------------------------------------------------------------------------------------------------------------FPADPAASF--FAYRDVESYL--------DYQAEKFVD--RF----------------DANS-------------YLYLTRAMDDYDLAEGYEDD--------------------------------------------------------------------------------ADAV-AAFEGEALLLSFTGDWHFTTEQAESLAES-----FRDTS-----V--P-VA---HHVIESDHG-HDAFLV-----EP-EK--VGPPVRDFLDAGVAGRSVHDTVEEV---EEPS-------VERDFAPVHTSLFSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9firm-a1hqe6 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPFLKYAKVADPD-NPLVL-------------TMGG--------TL-TDVTVAYETYGTL------------------SPNR----DNVILVTHALTGDSHVAAHDDK-------D--------EKGWWDALVG-PGR-PIDTNRFFVICSNVLGGCRG------TTGPSSP-DPA-------------------------T--GRPYGMRFPV---------------ITIRDMVH-----------------VQKRLL-EQLGIYRLVL--VIGGSMGGMQALEWGVTYP----EF-----------MDGIIAIAAPGY----SS--AQS---IAY-NKVAREAVMLDPAWR--QGDYYGG----------PGPQTGLSIARGLGMITYQSEPSMAAKFGRRMR--------------------------------------------------------------------------------------------------------------------------------------------------GGQFEVENYL--------DYQGISLVR--RF----------------DANS-------------YLYLLRALDLHDLGAGY--AS------------------------------------------------------------------------------YEAALAR-IEARVLIVGVSSDILYPAYQQQELVEV-----LRRLG--------K---AARYAQIDSPHG-HDGFLI-----DF-DAL--SPVLSDFINTIAPPVRLPWAQSFF---RASS-----------LAYFGARLVPEF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9firm-q2agf8 ---------------------------------------------------------------------------------------------------------------------------------------------------------------M------------------------------------------------------SFSALNEPGQSGIGEVS-----PAKILIK-EGLTL-------------ENGE--------KL-KPVTITYECYGRL------------------NSKR----NNVILVVHHLTADAHVAGYYP------HED--------RYGWWDDLIG-PGQ-IIDTDRYFVICSNILGSCYG------TTGPCSI-NPE-------------------------T--GEPYGPDFPV---------------ITVKDMVK-----------------AQFKLL-RKLGIKGIDT--VIGGSLGGMQALRWGVDYP----EL-----------VRQVVAISAPAR----LR--ARE---IAY-NTIASRAIKNDPDWQ--GGRYYNT---G------RYPVKGLQLARMVGMLTYRTPDLFQERFGRKMK--------------------------------------------------------------------------------------------------------------------------------------------------NREFEVNNYL--------EYQGQKFTG--RF----------------DANS-------------LLCLNKAMDLFDLARGY--SS------------------------------------------------------------------------------LEEAISR-IKAKTLIITTDTDQLFDPGESVEIVEI-----MLKQG--------K---KAYHREIKSRYG-HDAFLI-----EF-RKL--AKILNNWFS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9flao-q1vqu4 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPEIFKYQDPFQL-------------ENGE--------VL-PELEVSYSTLGKL------------------NKEK----SNVIWVCHALTANAQ-----------------------PEDWWRGLIG-NEK-GIDTEKYFIVCANIIGSCYG------STNPKSI-NPET------------G---------------EVYGLNFPL---------------FSIRDVTK-----------------SLELLS-EALEIEHIQF--LIGGSMGGMQAMEWAIEKP----DK-----------IKNLILLATNAK----HS--SWG---IAL-NETQRMAIEADSTFY--KK-------------ETNSGKKGLEAARAIALLSYRNYNTYRHTQV-----------------------------------------------------------------------------------------------------------------------------------------------DQEHT--ADHFRASTYQ--------KYQGEKLSK--RF----------------NAKC-------------YWYLSKAMDSHNVGRNRGDC--------------------------------------------------------------------------------KKAL-AKIKAETLVIAVQSDLLFPVEEQRFLAQY-----IP----------K--GK---LEIIDSIYG-HDGFLI-----EV-EK--IKSLVHKHFKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9gamm-a0y9n9 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPEQSVGIVTPQ-----SHHFA-QPIEL-------------ACGR--------SL-MQYDLVYETYGKL------------------NSDC----SNAILICHALSGHHHAAGYHHE-----NET--------KPGWWNSYIG-PGK-PIDSDQFYIVSVNNIGGCHG------STGPKSI-NPE-------------------------T--GTPWQNDFPL---------------LRCRDWVN-----------------TQRELM-KVLGIQQWAA--VIGGSLGGMQAMRWALEYP----DE-----------VRHCVVIASALK----LS--AQN---IAF-NEVARQSISSDPNFH--SGYYMSH---------NVIPKQGLRLARMIGHITYLSEDGMGQKFGRELKTGNFSL--------------------------------------------------------------------------------------------------------------------------------G------NDE--VVEFEVESYL--------RYQGDVFSG--SF----------------DANT-------------YILMTKALDFFDLAREY-NDD------------------------------------------------------------------------------PVEAFSN-ATCSFLVVSFTSDWRFSPERSREIVDA-----LVAAR--------K---PVSYAEIEADFG-HDAFLI-----SN-ERY--EKVFRAYMQRVAGETV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9gamm-a0z2s0 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVQAGDVGLVTAA-----REVFS-ETLTL-------------TSGR--------TL-AGFELITETYGQL------------------NAQR----SNAVLICHALSGNHHAAGRYDL-----SDP--------KPGWWDLHIG-PGK-AIDTNRFFVVSLNNLGGCDG------SSGPNTM-NSA-------------------------T--EQPWGPDFPQ---------------VSVSDWVT-----------------TQVMLA-ERLGIESWAA--VIGGSLGGMQALHWAVHYP----ER-----------VRNCVALAAAAK----LT--AQN---IAF-NEIARQAILSDPDWL--TGHYQRE---------TVTPTRGLSLARMVGHLTYMSADGMSDRFGRDTRTPS---------------------------------------------------------------------------------------------------------------------------------------ETIDSD--ETVFQVESYL--------RYQGKQFST--RF----------------DANT-------------YLLMTRALDRFDIAADF-NDS------------------------------------------------------------------------------LNDAMAV-TTSRMLIIAFSSDWRFSPARSQELVDA-----LLASG--------R---PVSYAEIETDAG-HDAFLL-----DE-PHY--TGLFTAWMQQVVI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
9gamm-q1n435 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQHIPADSVGIVEPQ-----TAVFD-EPLEL-------------KSGR--------VL-PKYELVYETYGTL------------------NEDK----SNAILICHALSGHHHAAGFHSE-----DDT--------KPGWWDACIG-PGK-AIDTNQFFVISLNNLGGCHG------STGPTSI-NPE-------------------------T--DEPYGGDFPV---------------LRVYDWVT-----------------SQARLA-DRLGIECFAA--VVGGSLGGMQAMRWSIQYP----ER-----------LKHCVIIASAPK----LS--AQN---IAF-NEVARNTIMKDPEFH--DGHYLKH---------DTLPKTGLMQARMLAHLTYLSDDAMGEKFGRDLKTDE---------------------------------------------------------------------------------------------------------------------------------------VSYEFV---PEFQVESYL--------HYQGEKFST--TF----------------DANT-------------YLLMTKALDYFDPAQYY-DND------------------------------------------------------------------------------LSKCLSQ-ATCKFLVMSFTTDWRFSPERSEEIVDA-----LIEAD--------K---DVTYACIESEKG-HDAFLI-----PI-PRY--VKTFGAYMNRIAKEDI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9gamm-q1yvf0 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPGISANSVGVVTAE-----KILIE-TPLTL-------------ACGV--------VL-PSHELMVETYGTL------------------NADK----SNALLICHALSGSHHAAGVYAE------GE--------KPGWWDAYIG-PGK-AMDTDRFFIVSLNNIGSCFG------STGPTTI-NPQ-------------------------S--GKPWGADFPV---------------LRARDWVE-----------------SQRLLM-EHLEIQQWAA--VIGGSLGGMQAMRWALEHP----DK-----------LANSIVIASSMK----LT--AQN---IAF-NELARRAIQSDPDFY--AGDYLDN---------NTAPRRGLALARMIGHVTYLSDELMGQKFGRELRSGTFTQ--------------------------------------------------------------------------------------------------------------------------------G------EAA--PIEFQIESYL--------NYQGEKFSG--DF----------------DANA-------------YILITKMLDYFDLSREY-QND------------------------------------------------------------------------------PVQAFSH-ANCDFLVVSFSSDWRFSPQRSREITDA-----LIAAG--------K---NVSFAEIDSDQG-HDAFLL-----PN-PRY--EQVLGNYLSRVADKLEGAA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
9gamm-q2brf1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPDVIPDDSVGIVEPQ-----KIEFS-EPLKL-------------QCGR--------TL-EQYHLMVETYGEL------------------NENC----SNAVLICHALSGNHHVAGYHSM-----EDK--------KPGWWDSAIG-PGK-AIDTNKFFVIGLNNLGGCHG------SSGPNQI-NPE-------------------------T--GKPYGPDFPI---------------VTVNDWVE-----------------SQARLA-DYFGIEQFAA--IIGGSLGGMQALQWSINYP----DR-----------LRHCMVIAAAPK----LS--AQN---IAF-NEVARQAISQDSQFY--NGHYYEK---------DEVPKVGLMLARMLGHITYLSDDGMRNKFGRELRSGQ---------------------------------------------------------------------------------------------------------------------------------------ISYDFT---PQFEIESYL--------RYQGERFST--AF----------------DANT-------------YLLMTKALDYFDPAADA-DGN------------------------------------------------------------------------------LSGILEK-AKAKFMVISFTTDWRFSPERSQEIVDA-----LVEAD--------R---QVSYAEIEAAHG-HDAFLI-----PI-PRY--LDVFSAYMQQVEADTKAVFFGGNA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9noca-q6rej1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIENP--YY------------------------TN---E-FH---GDYELIGIGQLDL-------------EEGG--------SI-PDCQLAVATFGVL------------------NEAK----DNAILIPTWYSGTHQIWRD-------------------------VYIG-PDH-ALNPEKYFIVCIDQIGSGLS------VSPHNAA-G----------------------------ANAGIAMSKFPH---------------VRIGDNVV-----------------AQERLLREHFGIERLAL--VTGGSMGAQQTYEWAVRFP----DK-----------VLRAAPIAGTAQ----NT--PGD---FLI-AEAMREAIQSSPGWN--GGEYT----------------------------SNEQVVDGLIRQAHIWA-----------------------------------------------------------IVGFS----------------------------------------------------------------------------------TEFWKHEVWRAM-----EFDSKEAFLS--GF-------LEPYFTA-MDPNA-------------LLTQSWAWQRGDVARH-------------------------------------------------------------------------------TGGDLAAAL-GRITAKTFVMPIDEDQLFPVRDCVPEQEL-----IK------------NSE---LRVVEDTLG-HLGLFG-VSPTYM-PQ--IDRHLGDLLDIEV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9plan-a6c8y9 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----A------------TQQELSETRQDSGVGIVQTR--LATLFAPP-NWLKL-------------AGGG--------EL-GPIQVAYETYGEL------------------TPAK----DNAIFICHALTGDAHAAGYYED-----DD------EKAKPGWWDDLIG-PGR-TLDTNKYYVICANVLGGCQG------TTGPGSI-NPE-------------------------T--NQSYRLGFPF---------------ITVGDIVE-----------------VHSALI-KHLGIDQLLA--VIGGSLGGMQVLEWATRFP----DQ-----------LRGAICLASAAQ----LS--AQG---IAF-NAVGRRAIKTDPEFK--DGEYEVG----------AGPRYGLALARMIAHITYLSDQSIEMKFGRRLQDHDTF--------------------------------------------------------------------------------------------------------------------------------------TY-EMLPEVEFQVESYL--------HYQGKRFVE--RF----------------DANS-------------YLYLTRAMDYFDLVS-Q-HGS------------------------------------------------------------------------------LVKALGK-TDARFLIASYDSDWLFTTSQSKEIVRA-----LIECG--------K---HVSFIELKSPFG-HDSFLI-----EI-EQL--NKMITPFLEQAYSSRLAESNRT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9prot-a6da27 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNIKTKIAKFT-KPLYL-------------ESGR--------IL-EPWQIIYETYGEL------------------NEDK----SNAILITHALSGSHHAAGWYK------GDR--------KPGWWDGLIG-DSK-AIDTTKYFVICTNVIGSCFG------STSPMSPIYPG-------------------------S--NERYRLKFPV---------------ITIKDMVK-----------------AQKILL-DSLGIKKLKA--VVGGSMGGMQALRFGVDFP----GF-----------VENIIPIATTYQ----TR--PYV---IAI-NKSMIEAIRADCEFK--NGNYEIG-----------KELKGLAVARMIGYLNYISPKTFDKKFGREYV--KTDG-------------------------------------------------------------------------------------------------------------------------------------MF-EL--FGRFQVESYL--------EYNGAMFPK--WF----------------DALS-------------YIYLLKAISLFDIGRGF--NS------------------------------------------------------------------------------LDEAFSN-IKDKLFLISFSGDTLFFPEEMREIKKY-----MDKVG--------G---RCQYYEIDSDYG-HDSFLV-----EI-DKF--SDLISDILKGEMDARF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9rhiz-q0g660 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAI--------------------AVDEELTRAAGSREAYEPSS--PVAEFGAS-EPLRL-------------DAGI--------DL-APFRIAYNTYGEL------------------NADK----SNAILICHALTMDHYPASPSPT--------------TGKPGWWSPLIG-EGK-PIDTTKFFVICSNVIGGCGG------STGPASL-DAA-------------------------S--GDPFGLNLPV---------------ITVRDMVR-----------------AQKMLV-ERFGIDTLFA--VVGGSMGGMQVLEWTVSYP----DK-----------VFAAVPIATGAR----HS--AQN---IAF-HEIGRQAVMADPEWH--GGRYFQK---------GKRPTKGLAVARMTAHVTYLSEMALHRKFGRNLQDRDTF--------------------------------------------------------------------------------------------------------------------------------------GY-GF--DADFQIESYL--------RHQGSTFVD--RF----------------DANS-------------YLYLTRAMDYFDIAADF-QGL------------------------------------------------------------------------------LANAFQG-SKTRFCLISFSSDWLFPTAESREIVHA-----LNAAA--------A---SVSFVEVETDKG-HDAFLL-----DE-PDF--YRAMDGFLSSAARARGLCE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
9rhiz-q1ygb0 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAE--------------------PSREQLDYSLGSREANEPSS--PVARFGPD-EPLHL-------------DAGR--------DL-SPFQIAYNTYGTL------------------NADK----SNAILVCHALTGDHYPASRSPV--------------TGKPGWWSSIIG-EGK-PIDTSKYFVICSNVIGGCMG------STGPASI-DPA-------------------------T--GKPYGLGLPV---------------ITIRDMVR-----------------AQAMLV-KRLGIDTLFA--VIGGSMGGMQVLQWTVSYP----ER-----------VFAALPIATGAR----HS--SQN---IAF-HEVGRQAVMADPDWQ--GGRYFEF---------GKRPHKGLAVARMTAHVTYLSEMALQRKFGRNLQDRDQL--------------------------------------------------------------------------------------------------------------------------------------GF-GF--DADFQIESYL--------RHQGMTFVD--RF----------------DANS-------------YLYMTRAMDYFDIAGDY-DGR------------------------------------------------------------------------------LANAFRG-SKTRFCMVSFSSDWLFPTEENRAVVHA-----LNAAA--------A---SVSFVEIDTDRG-HDAFLL-----DE-PEF--FAAIDGFVSSAATARGL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9rhob-a0nwz6 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAD--------------------TSRPATPEDLKASEAVSPSS--KLARFPAE-EPLEL-------------DAGV--------RL-GPWQIAYETYGEL------------------NAEK----SNAVIVCHALTGDQYVASTNPV--------------TGKPGWWSQMVG-PGK-PIDTNHYFVICSNVLGGCLG------TTGPASI-NPE-------------------------T--GQAYGLALPV---------------ITIRDMVR-----------------AQARLV-DHLGIDTLFA--VIGGSMGGMQVLQWAASYP----ER-----------VFSAVPIAAAAR----HT--SQN---IAF-HEVGRQAIMADPNWC--GGSYLQQ---------GQRPTKGLAVARMAAHVTYMSDESLHQKFGRNLQDRENV--------------------------------------------------------------------------------------------------------------------------------------TF-GF--DADFQIESYL--------RHQGMTFVD--RF----------------DANS-------------YLYVTRAMDYFDLAHQF-GGS------------------------------------------------------------------------------LANAFKG-TKTRFCVMSFTSDWLFPTSESRRVVKA-----LNAAA--------A---NVSFVEIESDRG-HDSFLL-----DV-PEM--FQTISGFITGAAHARGLPAPGEEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9rhob-a3uhc4 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M------TA-----------LASSSPERCRT-AQWR-----------V-QEYSCGFER-------------PHGG--------GW-S--DVRGRVVGPN-------------------------DGAVTIVLGGISADRRLIE-D--------------E--DGPGWWPGVAE-VGG-ALDPTRRRLVSMDFLDDAAE------P-----------------------------------------------F---------------PTVDDQAA-----------------AVLMLA-DTAGIER-FA--LVGASYGGSVGLSLAAMAP----ER-----------VSRLDLLCASAG----VH--PMT---QGL-RAIQREILKLAIEAG--QG------------------ARGVDIARRLAMTTYRTPEEFARRFGPE----------------------------------------------------------------------------------------------------------------------------------------------------GEPGGVEAYL--------SARGADYAR--TV----------------TPER-------------FLSRLASMEAANPDLS------------------------------------------------------------------------------------------AITCPVNLLAFTSDRLVPLEEVEATRAA-----LTG----------CDSR---LVVHDSPYG-HDAFLK-----EA-AR--VNAFLEGRHD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9sphn-q1n9s7 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA-------------------------------SLPRSDDSRFG--LRRQVRLA-GPIAL-------------SSGA--------SL-GPVDIAYETYGAM------------------NADK----SNVILICHALTGDQYVASDHPV--------------TGKPGWWWRLVG-QGK-PVDPARHFIICSNVIGSCMG------SSGPASV-DPA-------------------------T--GEPHAMRFPV---------------LTIADMVR-----------------AQAALL-DHLGVERLSA--VIGGSMGGMQALTWPTLFP----DR-----------VESCVVIASTAR----HS--AQN---IAF-HEVGRQAIMADPNWR--GGDYYAD---------GMVPSAGLAVARMAAHITYLSEAGLTEKFGRRLQGRDAK--------------------------------------------------------------------------------------------------------------------------------------TF-GF--DADFQVESYL--------RHQGLSFVD--RF----------------DANS-------------YLYITRAMDYYDIAEDH-GGS------------------------------------------------------------------------------LARAFAAT-RARFCLVSFDTDWLYPTAESRAIVHA-----LNAGG--------A---QASFVELSSPFG-HDAFLL-----EC-PEL--NRVVDGFLRGGRA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
9sphn-q2n7g7 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSN--PHTSLTLP-NPLPL-------------DSGQ--------AL-ACVEMAYETYGTL------------------NADK----SNAILICHALTGDQYVASTHPI--------------TGKPGWWERMVG-PGK-PIDTDRFHVICANVIGSCLG------STGPQSP-A-S-------------------------D--GEPYAMRFPV---------------ITIRDMVR-----------------GLVAML-DAMGIAQLHT--VVGGSMGGMQALSLAANWP----DR-----------AGRVLAIATTAR----HS--AQN---IAF-HEVGRQAIMADPHWC--GGDYYGE---------ESAPDAGLAVARMAAHITYLSEEGLTEKFGRRLQDRDAK--------------------------------------------------------------------------------------------------------------------------------------TF-GF--DADFQVESYL--------RYQGSGFTR--RF----------------DANS-------------YLYITRAMDYFDIAEEH-GGT------------------------------------------------------------------------------LAKAFAGT-PARFCLVSFDSDWLYPTAESRHVVHA-----LNAAG--------A---PVSFVELSAPFG-HDSFLL-----DV-PAL--DRVVKGFLDG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aciac-a1twh1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFIATPQ-----SMHFA-EPLPL-------------QGGA--------SI-RDYTLAYETYGTL------------------NADR----SNAVLVCHALNASHHVAGVYEG-----QPR--------SEGWWDNMIG-PGK-PVDTDRFFVIGINNLGSCFG------STGPMHT-HPD-------------------------T--GEVYGADFPV---------------VTVEVWVN-----------------AQARLL-DRLGVQQLAA--VLGGSLGGMQALSWTLQYP----ER-----------MRHAVVVASAPN----LT--AEN---IAF-NEVARRAIVTDPDFH--GGHFYRH---------GTIPKRGLRIARMIGHITYLSDDVMNEKFGRQLREGL--------------------------------------------------------------------------------------------------------------------------------------APRYSTQ--DIEFQIESYL--------RYQGDKFSD--YF----------------DANT-------------YLLITRALDYFDPALAF-GGN------------------------------------------------------------------------------LTLALAR-ARAKFLLVSFTTDWRFSPARSREIVKA-----LLENR--------R---DVSYAEIDAPHG-HDAFLL-----DD-ARY--MGLMRSYFDGIARETSA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aciad-q6feq3 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFPSDSVGLVTPQ-----KFQFE-EPLHL-------------ECGR--------VL-PRFELMVETYGTL------------------NADY----SNAILICHALSGHHHAAGYHHD-----DDK--------KAGWWDACIG-PGK-AIDTNKFFVVALNNIGGCNG------STGPTSP-NPE-------------------------NE-NRPYGPDFPL---------------VTVRDWVK-----------------TQALLS-DHLGIQSWYA--VIGGSLGGMQALQWSVDYP----DR-----------LKNCVIIASAPK----LS--AQN---IAF-NEVARQSILSDPDFY--HGRYLEH---------DSYPKRGLILARMVGHITYLSEEAMKQKFGRDLKSGK---------------------------------------------------------------------------------------------------------------------------------------FMYGF---DVEFQVESYL--------RYQGEQFSR--NF----------------DANT-------------YLIMTKALDYFDPSREY-EQS------------------------------------------------------------------------------LTKAMAQ-TQCRFLVVSFTTDWRFAPERSQEIVDA-----LITNH--------K---PVTYLDVDAEQG-HDSFLF-----PI-PLY--VKTLRAFLGGEAHLKSTPQVEIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
acib3-metx ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFPADSVGLVTPQ-----KFQFE-EPLHL-------------ECGR--------VL-PRFELMVETYGTL------------------NADK----SNAILICHALSGHHHAAGYHHE-----DDK--------KAGWWDSCIG-PGK-AIDTNKFFVVALNNIGGCSG------STGPTSP-NPE-------------------------ND-NRPYGPDFPL---------------VTVRDWVK-----------------TQAMLS-DRLGISVWYA--VVGGSLGGMQALQWSVDYP----DR-----------LQKCVVIASAPK----LS--AQN---IAF-NEVARQSILSDPDFH--HGRYLEK---------DSYPKRGLILARMVGHITYLSEEAMKQKFGRDLKSGK---------------------------------------------------------------------------------------------------------------------------------------FMYGF---DVEFQVESYL--------RYQGEQFSR--NF----------------DANT-------------YLIMTKALDYFDPSREY-GHS------------------------------------------------------------------------------LTEAMSK-TKCQFLIVSFTTDWRFAPSRSQEIVDA-----LITNQ--------K---PVSYLDIDAEQG-HDSFLF-----PI-PLY--VKTLRAFLGGEEHLKSTSLEAS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
acibl-q1ii02 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTGTCT--VSA-----------GEPIPAPRSQ--RNLHLI-QG---A--FTFADEGFPL-------------DNGG--------SL-RPVTIRYAQYGEP------------------NAKA----DNVVLVCHALSGSAK-----------------------VDDWWPELFA-EGG-LLDLDKFCVIGTNILGSCYG------STGPNSI-NAET------------G---------------QPYGADFPL---------------VTISDIVR-----------------AQAKLL-DHLGIKKLKL--AIGGSIGGMQALHWAMDYP----DR-----------VEQAIAIGTA-P----LG--ALG---LAL-NHIQRQVIRLDPKWN--AGSYS----------HENSPSQGISIARQIAMLSYKSAELFDERYGRKLNRNGED--------------------------------------------------------------------------------------------------------------------------------------PYTHH--EARFDVGGYL--------DHQGEKFVQ--RF----------------DANS-------------YVSITRTMDTFDPVRKYRSA--------------------------------------------------------------------------------KAAY-SRIKAKITLVGISSDWLFPPEDVRKLAQE-----MIAAG-----A-S--CD---YREIISAHG-HDAFLA-----EP-EK--LLEVLSDAHARPV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
acicj-metx --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDQSP------FPDI--AHQTASFS-DGLVL-------------DCGT--------TL-QRLEVAYRTYGSL------------------NAEK----SNAILICHALTGDQYVAEPHPL--------------TGKPGWWNALVG-AGK-PVDTDRFFVICANVLGGCMG------STGPRSR-RDHG------------------------A--DEPWSIDFPA---------------ITVQDMVR-----------------AQKKLV-DWLGIERLFA--VVGGSMGGMQVLAWASLFP----DR-----------VFAAVPIATAPY----HS--AQN---IAF-HEVGRQAIYTDPDFH--GGHYRTH---------GVIPARGLAVARMTAHITYLSEAALTRKFGRRLQRQNALA-------------------------------------------------------------------------------------------------------------------------------------AP-VF--GERFAVESYL--------EHQGSSFVR--RF----------------DANS-------------YLVITRAMDYFDLAADH-GGS------------------------------------------------------------------------------LSAAFRG-TKTRFLLVSFSSDWLFPTAESRAMARA-----LNQVA--------A---NVSFVEIVSDKG-HDAFLL-----DE-PDF--HRTVAGFISGAAEAAGLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
acif2-metx -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVEIPADSVGLVTPQ-----TVTFS-APLEL-------------ECGR--------SL-PGYTLTYETYGTL------------------NAQR----SNAILLCHALSGDHHAAGYHSM-----DDR--------KPGWWEHLLG-PGK-AMDTERFFFVCANFIGSCKG------STGPAST-NPE-------------------------T--GAPWGLDFPM---------------VTVRDWVK-----------------TQAELA-DYLGIEQWAA--VVGGSLGGMQVMQWSMDYP----ER-----------LRHAVVIAAAPK----LT--AQN---IAF-NEVCRQAIMTDPEFY--NGRYYAH---------NTKPRRGLSLARMIGHITYLSDNAMRTKFGRDTRGGK--------------------------------------------------------------------------------------------------------------------------------------AFSFGF---DVDFEVESYL--------RYQGSSFVE--RF----------------DANS-------------YLYITKALDYFDPASTW-GGN------------------------------------------------------------------------------LAEAFAS-TRANFLVISFSSDWRFSPERSREIVQA-----LYTCN--------R---DVSYAEIEAEHG-HDSFLM-----PI-PQY--VAVLSTYLGRVAEEIGA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
acisj-a1wda1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSFIATPQ-----TMHFA-EPLPL-------------QSGA--------SI-RDYTLAYETYGTL------------------NADR----SNAVLVCHALNASHHVAGSYAG-----QPR--------SEGWWDNMIG-PGK-SVDTNQFFVIGVNN |
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