Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....790..5....800..5....810..5....820..5....830..5....840..5....850..5....860..5....870..5....880..5....890..5....900..5....910..5....920..5....930..5....940..5....950..5....960..5....970..5....980..5....990..5....1000.5....1010.5....1020.5....1030.5....1040.5....1050.5....1060.5....1070.5....1080.5....1090.5....1100.5....1110.5....1120.5....1130.5....1140.5....1150.5....1160.5....1170.5....1180.5....1190.5....1200.5....1210.5....1220.5....1230.5....1240.5....1250.5....1260.5....1270.5....1280.5....1290.5....1300.5....1310.5....1320.5....1330.5....1340.5....1350.5....1360.5....1370.5....1380.5....1390.5....1400.5....1410.5....1420.5....1430.5....1440.5....1450.5....1460.5....1470.5....1480.5....1490.5....1500.5....1510.5....1520.5....1530.5....1540.5....1550.5....1560.5....1570.5....1580.5....1590.5....1600.5....1610.5....1620.5....1630.5....1640.5....1650.5....1660.5....1670.5....1680.5....1690.5....1700.5....1710.5....1720.5....1730.5....1740.5....1750.5....1760.5....1770.5....1780.5....1790.5....1800.5....1810.5....1820.5....1830.5....
9hyme-e2a9y2   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGRV--------------VSFFVLLLCSLIN---------------------ARDVELIRRKRIVGGTAAAQPPKDDP----------VVFVNKNDRHARIIGNRDP---------DKGFYIFRGIRFGEPPT-GRARFQRASP-VY----------------LEGEYNATTWGPPCPQPAYDG-----------------------------TNKIIGSEDCLFLNIFTPSLPD----------------TT---DGYPVLIWIHG-GGFRKGAACQYE----M--------RHLIK-KKMIVVSIQYRLGTLGFLSTGTSE---MPGNNGMFDMILAVDWVKDYIHFFGGNPKKIVAFGHGTGASSAMM---LSLSK-FCEN--SFSGLIAMSGSILS--HFAVDKN----PFETARY-------I-----------------------------------A-------------RKNSCP-------IND-TRRMVYCLRELPVEKLIRV-DSELEGI-RAAARGFVSSLSNLL-GSGPVVEGSNDGRS-LPNFMTASPEDSLKLGNFPSIPLLTGVMSDETGG---AVFGQYKDEVQ---------NKLNMAPDYLTNE---------FIPYLQGTIPN-MRNG-------------------------------------------------------------------------------LRFIP---------QAFN-GYF--------------------------------------------------------------------NIF--GS--------------------------------------------------------------------------------------------------------------------------DSMRNTIGRVA-----EALSDS--LYNAPAFLTVDHWSKK--ANAFLYTFDHKGKRKYG-KDFLAGLPIVDAKQS-------SNGNLNHGDDLGFIFDRNT-ITGEKISDN----------DEVDEVDENVTEIFTDMIANFARSGTFSVPTT---NIRSNGSAWKPDIIPNFSDKT-NSFISITT-DP--KS------MNNFR--------------------------------------------------YCEMGLWTAVPERLQSP-M---CS------------LYKA-PLQLIE-------QGT------TGT-ISVIQ--E-PI--NT---------------INEFVPDL-----KS-G--LNI--AN-------------------QSTNQN--------IK-EPN---------------------------KENT-------VQRKTNGRL---------------------------------LPKVPIPSIPFAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
9hyme-e2b2q4   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDRRV--------------SLLFILFLCSFVY---------------------ALDVNLTRQKRVVGGVPALQPPEDDP----------VVFVNKNGQHARIIGSRDP---------NKGFYTFRGIRFAKPPT-GDNRFQRASP-VL----------------LEGDYNATTWGPPCPQPSRDG-----------------------------TDRIIGNEDCLFLNVFTPSLPD----------------SS---DGYPVLVWIHG-GGFRRGSACQYE----M--------RNLIS-KKMVVVSVQYRLGSLGFLSTGTKE---LPGNNGMFDMILAVDWVKDYIHFFGGNSKKIVAFGHDTGASSAMM---LSLSK-FCKN--SFSGLIAMSGSILS--HFAVDRN----PADTAKD-------V-----------------------------------A-------------RHNGCP-------IDN-TREMVSCLREVPAEELIRT-DSRLENV-RMVAQGFISGLSNLL-GAGPVLEGADDNRS-LPNFLVESPEDTLKFNNFPSIPLLTGVMKDETGG---AISGGYKNEVL---------NKLNTIPNYLTND---------LVPHLQDTIPN-IQNG-------------------------------------------------------------------------------SRLVP---------QAFS-GYF--------------------------------------------------------------------NIL--QG--------------------------------------------------------------------------------------------------------------------------DGARDTIGKVA-----EAVGDS--LYNVPAFLTVDNWSKK--ANAFLYTFDHKGKKNYG-KDFLAGLPIVDAKQL-------SDGNLNHGDDLGYVFGPNT-ITGESMGKN---------DEEPDEADERVTEIFTDMIANFARSGTVNIPAV---SSRG----AMLDEIPTYSSDT-NSFVSITT-AP--QS------MRNFR--------------------------------------------------YCEMGLWTVAPERLQSS-M---CS------------LYKV-PLQLLQ-------QGV------KGT-ASMIE--K-PL--GT---------------LGGFASGL-----QS-G--LNF--AD-------------------KSENQN--------TK-VPR---------------------------EENK-------TQEGSRDRL---------------------------------LSKAPIPQIPFFG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
acrec-f4wah1   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGRI--------------VSFIILLLCLLTS---------------------ARDANVIRRKRIVGGAPAAQPPKDDP----------VVFVNKNDRYARITGIRDP---------DKGFYIFRGIRFGQPPT-GRARFQRASP-VY----------------LEGEYNATTWGPPCPQPSHNE-----------------------------TDKIIGSEDCLFLNVFTPSLPD----------------IS---GGYPVLIWIHG-GGFRRGAACQYE----M--------RHLIK-KKLIVVSIQYRLGTLGFLSTGTQE---MPGNNGMFDMVLAVDWVKNYIHFFGGDPNKITAFGHGTGASSAMM---LSLSK-FCEN--YFHGLIAMSGTILS--HFAVDKD----PSKTARH-------I-----------------------------------A-------------QKNDCP-------TND-TRRMVDCLRELPVEKLIST-DSKLENT-RTTVRGFVSGLTSLL-GPGPVIEGSNDGRS-LPNFMTASPEDSFRHDNFPSIPLLTGVMKDETGG---AIFGQYKDEVQ---------NKLSTIPDYLTND---------FIPYLQGIIPN-MQNG-------------------------------------------------------------------------------SRFVP---------QAFR-GYL--------------------------------------------------------------------NIF--QG--------------------------------------------------------------------------------------------------------------------------DGTPNNVGKVA-----EALGDS--LYNAPAFLTVDYWSKR--ANTFLYTFDHKGKRSYG-KDFLNGLPIVDAKRS-------LDGNLNHGDDLGFIFNRNT-ITGEKVSDG----------RKLDEADERVTDIFTDMIANFARNGMIGTPIT---NVRSNDSSWVPDIIPRFSDDT-NSFVSITT-AP--KI------MNNFR--------------------------------------------------YCEMGLWTAVPERLQSP-T---CS------------LYKV-PLQLIQ-------QGA------KET-ISIIQ--K-PI--DT---------------LNTFVP-------KS-G--LNT--AN-------------------KSTDQN--------TE-KPK---------------------------EDTT-------KQ-TNNRLLPKIP-----------------------------IPKVPIPQIPFGG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
acrec-f4x3l5   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKHATW--------------LLFAFTLLL-VQRIHVSRAQ----------------------RTHARQGLNRENPTVKIP--------------GQG----TVLGKEIA------V-NTVRLTQYLGIPYAQAPL-GNLRFMRPVT-EP-------------LPSWTDVKNATQFAPSCPQATGQ-------LKLHEKLFMQLLPPDMPD--------PGFDENCLFLNIFVPSE------------------GNRQNDQWPVMVWFHG-GDFNTGTPAIWD----AS-------VFVSK-QKVLVVTVAYRLNILGFFTTTDSE---ASGNYGMFDQIAALDWIKRNIKYFNGSPNNIVIFGHNSGAISVGL---HMLSP-LSKG--KFHKAIAMSGDAIS--SVGTLER----EKPIVDI-------I-----------------------------------T-------------NKFGCD-------RRP-TSKLMECLRRLSADFLIKH-------------------SSDIE-SWGPIVDAEINN-E-TDPFLAQHPRDILENGNFNTVPLMVGYTNNEQVL---AYMEVISDKNPEGGLSS------ENFEMMITDE---------FTAAV-EISDD-NSTCESK-----------------------------------------------------------------------------PEMV---------ANAV-LFF--------------------------------------------------------------------YRPYPTT--------------------------------------------------------------------------------------------------------------------------TNMTVFRDRYL-----DLQTEK--NFAAGLTQLANKVAN-KKSTAFVYRFDYRPKTQPV-AKD-----------------VPEWAGVPHMFELPFVWGLPH-MTS-VGA------------TQWNFNDKRMSESMMTMLATFAKSGDPSFVER-----------TVSVKWEPYTEDN-PRILIIDK-NIEMNE------PGAVD--------------------------------------------------YKALAFWNEYYPQVMMEATNNCCN------------ITST-ATTWRIFS----HSVYLSGVMTT------V---------AF-----------------HR--------------------------------------------FWF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aedae-Q8T9V6   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCRNR--------------LLI----ILAGLLL---------------------LLTVVKRCEAIVGGIRSAPPPVDDP----------VVFVRYVGKSARVEGTRSR---------QTGLYSFRGIRYAEAPI-GEYRFQRPTF-KR----------------LSGDVNAINNGPPCPQPEPNN-----------------------------PYKVIGNEDCLLLNVFTPQMPD----------------ET---TGLPVVVWIHG-GGYRYGSAAQYG----G--------EPLTQ-NGVIFVPIQYRLGSFGMIGDGSRD---LSGNLALLDMASAVRWVKDYISWFGGDPNQIKVIGQGSGATAAMV---LTSAT-MARS--SISGVVAMSGSSLQ--PNTYDPA----PVTSLKE-------I-----------------------------------V-------------AKHDCS-------TGN-ETEIVKCMRGKSVQDIIKV-DSELQVS-RLSDQKAVKALTGNV-GVSPVVEPKDDGRG-LLGVMTEKPEETINRGDFPKVPLLIGVTKDETAN---FIDVKEIEKAF------------ASPSNFLKST---------SK--IVG-LDN-FLNTNKSVAL----------------------------------------------------------------LD-----SLGTI-----------LDLT-QYL--------------------------------------------------------------------EIP--KA--------------------------------------------------------------------------------------------------------------------------WNATQIFGKLV-----EATTDA--VFNLPAIVTAQAWSKS--SKSFFYSFEHRSDNTKG-SDFLKGLPLVAKTNN-E----KQKNIVAHGDELGILFDTHD-VHGNLIEKA----------AIKSKRDINARQAFATFIAKFVHMNASN--------------PRDDSLFKPFSSKG-TPYIKIGE-QI--TS------ENDFR--------------------------------------------------FCQLSIWGAQLEALKSI-S---CQ------------FLGD-GLGSIG-------KVV------GQLTGILGG--Q-RPPV-----------------PNNVFGI------FG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
aedae-q1dh58   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTEGYSVLVWFPT-GDFDGDTPFQLN----PF-------QMVFK-QKLIVITVQYRLGIFGFFTTMDGS---APGNFGLMDQSAALLWIKRNIKLFNGNEASVTIMGHGTGAVCVGL---HLMSGEWTDE--MFHKAIMMSGSVLLDSMVKSPKM----YGSALDE-------M-----------------------------------A-------------TSFGCF-------RKP-TASLIDCLRRVGGQLLAE--------------------NSPVI-DWGPVVDSGLSN-I-TTPFIPDFPMMLVHQGKLRKVPLLIGHTDMEEGL---ELAM---GDMLEHGIGS------EMFETLLGDA---------VMMDLNQLDFN-DTLCGGN-----------------------------------------------------------------------------MEIV---------MDAV-QFQ--------------------------------------------------------------------YKPYPPT--------------------------------------------------------------------------------------------------------------------------TDPMKLRRRYI-----EFATER--KFVAPTIELAMHMS--QLAETYVYRFDIKPRTEAA-MKD-----------------IPEWMGVPHNFELIFLWGLPY-WLMLADG------------MQWDSADKRVADIVMTLWANFAKFTNPTQVG------------VY-IKWDTFTNDE-PGVLIIDR-SFNMSD------HSTMS--------------------------------------------------FGAVKFWNQYYPNVIQFAA-QCCN------------ATYM-AGAGNSYQTMLSSSVV---------LNVTVGWGNCVRL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoda-e3x0s6   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYVSSSLAW--LLC---------------------VATAIGPGEAIVGGIRSAVPPLDDP----------VVFVRVGGRAARVEGTRNR---------ATGLYSFRGIYYADPPT-GEYRFTRSRF-RH----------------LSGDVNATRNGPPCPQPDPTN-----------------------------PYRVVGNEDCLLLNIFTPQMPD----------------ET---TGLPVVVWIHG-GGYRYGSASQYG----A--------EPLTS-NGVIFVPIQYRLGSFGMIGDGSRD---FSGNLALLDMATAVRWVKDYIGWFGGDPAQIKLVGHGSGATAAMV---LASST-MARS--SVTGVVAMSGSSLQ--PNAYEVE----PVMAYKE-------A-----------------------------------T-------------GKHRCM-------AGN-ETEVVRCLRMHTTNEIVLM-DNELQTD-RFHGEKLINGMTPNA-GVNPIVEEKDDGRG-LPGLLTDKPETILSEGDIPKIPLLIGVAKDETAN---AIDVKEVQSVF------------KGATNFLRKT---------SS--LVG-LDA-FLNVEKQLSG----------------------------------------------------------------LD-----TVGGV-----------LKLD-KYL--------------------------------------------------------------------EVP--NG--------------------------------------------------------------------------------------------------------------------------LDPTVVLGKLI-----EATTDA--IFNLPAVVSAQAWSKA--SQAFMYSFDYRSERTRG-KDFLAGLPIVNKSGT-NG---APPEAVAHGDELGLLFDTQD-LYGNPVPTA----------KITSPKDQNARKSFASFIAKFAYLNTSS--------------MHQDNVFKTFSSKG-TPFVKIGE-KI--TV------DNDFR--------------------------------------------------FCQLSLWGAQLESLKSI-S---CS------------FLGQ-GLGSVS-------KVV------GNVLP-----------------------------PNPVSGFL-----FG-G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoda-e3xbi5   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLV---------------------------------MLRCQGAAGRDPPTVTIP--------------DQG----TVMGMYMK------MFRTQRVVAYLGLPYAQAPV-AEKRFTPPVV-DN-------------LPSWEGVKNATSPAPHCWHMPRDT------HRRHNQLFMELIQMNDDA-----GTERQYDEDCLFLNIYIPDRPNRGEQRLENSSTKPSSTSTMPTDGYSVLVTFPT-GDFDGDTPFTLN----PF-------QMVFK-QKIIVVTVGYRLGIFGFFTSVDGE---APGNFGLMDQSAALLWVKRNIRLFNGNEESITIMGHGTGAICVGL---HLMSGEWTDD--MFHKAILMSGSVLMDSSVRPAKQ----YASALDE-------L-----------------------------------A-------------TAFGCF-------RRP-TTKLMDCLRR-----------------------------------WGPVIDRGLSN-T-TTPFISDHPNMLVHQGKLRKVPLLIGHTDMEEVL---ELTM---GDVVEHGLGV------EMFETLLGDV---------VMNDLAEMDFN-ETLCGGN-----------------------------------------------------------------------------MDIV---------MEAV-HYQ--------------------------------------------------------------------YKPYPPT--------------------------------------------------------------------------------------------------------------------------TDPLALRRKYI-----EFATER--KYVAPTIELAMHMS--QQADTYVYRFDIKPRTAVA-LKD-----------------IPEWVGVPHNFELIFLWGMPY-WLALADQ------------MQWDSADKRVADIVMTMWANFAKFTNPTQVG------------VY-IRWEKFTVTE-PGVLIIDR-SFNMSD------HTTMS--------------------------------------------------FGAVKFWNHYYPSVINFAA-QCCN------------ATFS-GSASKHLASGVAVVLCAVLLQS----------------FAY---------------VHTRFLLV-----RP---------T----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoga-agCG49510	-----------------------------------------------------------------------------------------------------------------MLPATV-IIAVVVFTVSLVA----PIN----------S------AGSGS---SSP----------------------SNGGPGSN---SMDENET--------------------------------------------LKKST----SSRIVHTKYG----AVSGT----IEHLDGRHLDPVEAFRGVPYASPPV-GNLRFMPPVT-GA---------------LWSGVKKADRLARAPFQR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoga-agCG56978	------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVTVSTVPSRTF--------------TRLV--LLL---------------------------------ALLCRGGLGRDPPTVTIP--------------DQG----TVMGMYMK------MFRTQRVVAYLGIPYAQAPV-NEKRFTPPVV-DN-------------LPSWEGVKNATSPAPHCWHMPSDT------HRRHNQLFMELIRSGDDGGGGDGGGDRQYDEDCLFLNIYIPD-------------------STMPTDGYSVLVTFPT-GDFDGDTPFTLN----PF-------QMVFK-QKIIVVTVAYRLGIFGFFTSMDGE---APGNFGLMDQSAALLWIKRNIRLFNGNEGSVTIMGHGTGAVCVGL---HLTSGDWTDD--MFHKAILMSGSLLLDSSVRTAKQ----YASSLDE-------L-----------------------------------A-------------TAFGCF-------RRP-TTKLMDCLRRVDAQILAE--------------------NSPPI-DWGPVIDQGLSN-T-TTPFIPDHPNMLVHQGKLRRVPLLIGHTDMEEVL---ELTM---GDMLEHGLGA------EMFDTLLGDV---------VMSDLAEMEFN-ETLCGGN-----------------------------------------------------------------------------MDIV---------MEAV-QYQ--------------------------------------------------------------------YKPYPPT--------------------------------------------------------------------------------------------------------------------------TEPLALRRKYI-----EFATER--KYVAPTIELAMHMS--QQADTFVYRFDIKPRTAAA-LKD-----------------VPEWVGVPHNFELIFLWGLPY-WLALADQ------------MQWDSADKRVADIVMTLWANFAKFTNPTQVG------------VY-IRWEKFTVTE-PGVLIIDR-SFNMSD------HTTMS--------------------------------------------------FDAVKFWNHYYPSVINFAA-QCCN------------ATYN-GAER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoga-ebiG239  	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRKK--------------PFLRHAVAFCVPPL---------------------LALLATPGEAIVGGIRSATPPIDDP----------VVFVRVGGRAARVEGLRNR---------NTGLYSFRGIHYAESPT-GQNRFARPQY-RH----------------LSGDVNATSNGPPCPQPEPSN-----------------------------PYRVIGHEDCLLLNIFTPQMPD----------------ET---TGLPVVVWIHG-GGYRYGSASQYG----A--------EPLTS-NGVIFVPIQYRLGSFGMIGDGSRD---LSGNLALLDMATAVRWVRDYIAWFGGDPAQIKLVGHGSGATAAMV---LASAT-MARS--SVTGVVAMSGSSLQ--PNAYEME----PVGAYRE-------A-----------------------------------T-------------MRHRCA-------AGN-ETEVVKCLRDKTTEEIVQM-DTELQAE-RFRGEKLVNGVTPQA-GLNPVVEEKDDGRG-LLGLLTDKPEVSLQAGDFPKIPLLIGVTKDETAN---AIDVKEIQSTF------------KGATNFLKKT---------SS--LVG-LEG-FLNVEKQVQA----------------------------------------------------------------LD-----TVGGI-----------LQLD-KYL--------------------------------------------------------------------EIP--AG--------------------------------------------------------------------------------------------------------------------------WDVTQIFSKLV-----EATTDA--VFNLPAVVSAQAWSKT--SKAFIYSFEHRSDSTKG-RDFLAGLPIVAKTGT-NG---ADGRLVGHGDELGLLFDTHD-VYGNPIASA----------TVKSAKDLNARKSFASFIAKFAYLNTSS--------------MHQDNVFKSFSSKG-TPFVRVGE-KI--AV------DNDFR--------------------------------------------------FCQLSIWGAQLEALKSL-S---CS------------FLGE-GLGSVS-------KVV------GNVVP-----------------------------IN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
apime-h9ken5   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCRRM--------------I-IVIFLFYVLTI---------------------VTSYNLKRQKRIVGGRTAAPPPVDDP----------IVYVTQNERQARIYGTRDP---------NKGFYVFRGIRFGLPPI-GRYRFQRPRL-LH----------------LKGEINATQWGSPCPQPNNIN-----------------------------GQKIEGSEDCLFLNVFTPMLPD----------------SS---DGYPVLIWIHG-GGFRRGSACQYD----M--------RNLIK-KKLVVVSIQYRLGSLGFLSLGTKE---LPGNNGIFDMMLAVKWVKNYIQYFGGNPKKIIAFGHGTGASAAFM---LALSK-LSKN--NFSGLIAMSGSILS--HFAFDKN----PASTAQY-------I-----------------------------------A-------------SNNGCP-------TNN-TIEMIRCLQEIPVDKLIQV-DSNLETV-RSAVQGFISSLSTLL-GPGPVIEGNDDGRF-LPNFITNTPENTLKIGDFPSVPLLIGVMNNEVGG---AIFGDYKSEIE---------NKLRTIPNFVNEH---------FIPTLQSTVSN-FGNI-------------------------------------------------------------------------------SRFTP---------QAFN-KYF--------------------------------------------------------------------NIF--NT--------------------------------------------------------------------------------------------------------------------------RNNSAQIAKIA-----EAMGDS--LYNVPAFLTANHWAKK--SESFLYSFDHKKTRKCG-RTFLSELPIVKAKHA-------SDDIISHGDDLGYIFKENS-IFGEPSQCI----------EELNEENERVENIFTNLIAEFAKSGKPDI------RFSSQNNTLLPNMLPKFSDEI-NPFISITS-TP--RI------MEQFR--------------------------------------------------YCEMGMWTGLEKRLQST-S---CN------------FLKS-IVDIVD-------NTE------KVN-KTVQ----------------------------NYLKNE-----AK-N--MSI--------------------------NNL--------IK-I-K---------------------------K---------------------------------------------------------YTSITF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
ascsu-f1ky57   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMKNWFCVVYI-------------------------FHIS-------------------------------------------VCLASAQTTDNELIRVLSTG----SLLKG---AKIIVNDN--STIHLYLGIPYAESPA-DQNRYKAPIK-RA---------------KWDGILDASYYKVSCLYDSPDFEVTLST--------------------------RFMSEDCLHVSVISSESCI-------------------QNGRCPVAVYLHG-SNFNYASSSVIPVEDIARR---------WATNDIIVVTTNFRLGSFGFLNLGEKTT--AVNNAGLLDQLEALRWVQREISRFGGDARRVTLMGFGSGAINADL---LAISP-TARG--LFQQVVIIGGAAGTMPNIN--ED------WNVAASR----------------------------------------------------SLAIESGCTTRFTWDT--TNKEDIVNCLRGRQASELLSV-QRMLENT------------SRL---YAFNLPAVDAREA--TPIIPNSVSTLS--KMRRGYTMMIGSISNSMN-WPNNAIKLDLFVPT-----------------------RK----------MLKAMCG-----------------------------------------------------------------------------------------------------VAMLH----------------------RHFNF-------------------------------------------T--V---------------------------------------------------------------------------------------------------------------------------KLVKA----CQ-----REYSTV--SLG-----------S-KLVE-DVAVFLPIYDSASA-NTRNGGTT-------------FLFDYLSDDKEESLLAFAPS-NSANITQ------------SDYVG----------TAISLFIKTGDPSSEA---------------LKWQPFEEER-NNFVALTA-AA-L---PMN--VNEYH--------------------------------------------------FEAVNFWTIMAPQIAEKAE------------------WLKENGT----------NILNDLVEAGKEG-IA----SFAEAIGSIRDKRRKAIIEAIGKIASALGSIEEEIAKQ-KEA-AVS-KG----IG-----WIQGHIIV--ADILVEV----------NNLLDGVLADVCEKSVDSAVMTTAKSGEEGMNSIEPALRASIVGSVARSAVSNGDA----------------------------------------------------------------------------------------------------------------------------------EM---VT-------I---------------ETADDYW-GTWTNGAWF---------WIIH-AAAVVIVV-----ALVAALATNCCSR--KSGRSYEILA----     =====>
ascsu-f1l0s5   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQAYSLLVISM---------------QFS---IILLLLP-------------------------------------------AAARVHATEDTFLIRTLSTG----KIRGK---RVDESNGT--LIGYQYNGIPYAQVPL-KDLRYRNPLP-PK---------------SWNNTLDTKHFKKSCSQTLL----ISNE--------------------------TTQIEDCLYLNVFSPCNCM-------------------KFRNCSIAFLIPD-YK--QSSAD-------VIG---------YIDENIVVVSTSYRMASFGFLNVNPLKDTVQDKNVGLYDIIESLLWIKREIVNFGGNALNVTVISSRNGAVLADL---LSLSP-LSEG--LFSRLVLISGSAAFRA-LS--NA------SDCFASR----------------------------------------------------QLSVQAKCAENYTKFAEVDASNIVLECLRSRDARYIETF-EASFAER-------------------GLRLGHPSAGPT--QKLFPTSFRNLT--LMRRPIAVLLIVSK-IER-LRDESL-LIRGKPD-----------------------MK----------RLGLICE--------------------------------------------------------------------------------------------------------------------------------RFAGL-------------------------------------------S--D---------------------------------------------------------------------------------------------------------------------------EFRER----CL-----HIYSSV--RMQ-----------K-WSIQSELWIYITIIEFIRH-QWKLQKLS------------MQRMDRHSYSSRTQILPLMASFAIAAASR------------RRFCR--------------------------------------------KPLR----VSF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
ascsu-f1l2e5   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSACQFLYAIPLLI-------------------------------------------------HLVLGCPKASTRYG----ELEGFTYP------MKNGKEAQVFLGIPYASPPI-DDARFEAPMP-MRP---------------WEGTRQAKQFGASCFPLRKDA------L----------------------SRQLQYSEACLYLNVMAPARKK------------------SGESSYPVLVYIHD-GGFESGSASSFG----YKRF----CDNLVS-EGIVVVSINYRVGFLGFWTTGDHA---LPGNAGLLDQTQALTYVNENIEAFGGDPLRVTILGHGSGAASATA---LSLSP-YANY--LFQQTISISGSIFS--QLAQSET----TIEDSLK-------L-----------------------------------A-------------ETVGCR-------NER-SKITRDCMKKKNIVELMNA-VNEVEAA---------HPRRNGV-KLRPVFDNN---FL-TP------PLEQLMSR-APHITSIVGLTNA--------ASGVLPKPIP--------SSKM---SKFSADD---------LTDYIKKEVAT-ESDFGAA----------------------------------------------------------------------------AEDFQ---------HKLI-EFF------------------------------------------------------------------V-RRDAPQH--------------------------------------------------------------------------------------------------------------------------ADSDFYLARLL-----EVMNDL--RFNVPLLYEIEMKREY-KWSTYFFVKEYDHQIN---QNI-----------------LQSIKGAHHADEYVYLFGPPE-VAGNIDF---------------ADDDITYQRVLLNSLIQFIKTGNPSH---------------ENLVWESIDDKHRSRYLNFSP-KP--HM------VEKYK--------------------------------------------------PENVYFWTQVVPTEIRERI---RT------------GKRLDTKDSYS-------HIH------TEL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
bommo-h9jy45   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYTTVK--------------------DYNVERYPTLVWFHG-GDFARGSPNNIN----PF-------QLVLN-QKVIFVSVAYRLNIFGFFSSLDNE---APGNFGLLDQTAALTWVKNNIASFGGDPDNVCIFGHDAGSVSVGF---HLLSP-YSAG--LFQKAIAMSGNVLSPDKVNVARK----EVITVNK-------V-----------------------------------A-------------RAFGCF-------REP-TSALLGCLRRVPFKALLNI-------------------GEPLA-QWKPIVDNGFSN-V-SGPVLSDFPSKLFEDEMFSPVPVLTGFTDMEDAL---FLEK----NGSDSGVSQ------REFDVMREEI---------ILADI---TVD-NSSCFTN-----------------------------------------------------------------------------QHHI---------QDAV-AFF--------------------------------------------------------------------YKPIPPT--------------------------------------------------------------------------------------------------------------------------SNETVLRKLYL-----EFYTDK--LHAAATYQLAKHIS--KHTSVYLYRFDWKPFSEVV-NEG-----------------ISDWIGVPHNFDLIFTFGLPY-LALPEDL------------DKWDRRDKRISDIVMKMWSNFAWYSNPTNSG------------VI-INWEPFEIEK-PGFLIIDRQNFSMST------AATVN--------------------------------------------------YKALEFWTDFYPKVVEIGT-KCCK------------ESFE-DNGVGPMIE---IRAR---YMPF-----LLTYVIILFS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
bommo-q1hq05   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M--------------IWHW---SCVVVL-----------------------LTWSAPATAVVGGAPASPPEPDAA----------VVFIQRHGRSARLEGLKDD---------KLGYYTFFGIRYAEPPL-GPRRFQRPVR-QY----------------LASELNATRQCLPCPQRDPYY-----------------------------PDRFMGHEDGLCLNVFAPKMPG----------------DE---RGCPVVFFVHG-GNYKSGSASAYG----G--------QHLTQ-KDTILVTAQYRLGSLGYLSTDERD---AAGNVGLFDLHAVMAWIQDYITFFGGDPTRVVVMGQGSGGSAASL---LAMSA-EGRT---ATGVAALSGAPLS--PGAVRPE----PAKHADT-------I-----------------------------------A-------------ERTGCP-------KRP-AESLIKCLRQVPVEKLIMA-DEDLSMDNAMDTMKFLDEISGRS-GAGARVEGEDDKRA-LPPIVSEKPADSLKK-KTKRPPMLTGVTSAETSR---AVFGKYNKFLT---------NQLQAVKDFIKKD---------LVGGLQGVVQG-VDGLLPITAV------------------------------------------------------------------------VGSILP---------ISLT-DYY--------------------------------------------------------------------GSVFNTT--------------------------------------------------------------------------------------------------------------------------LNAVDGLSQIV-----EATGDA--LFNFPAYQSVRQWSAG--GPAYLYSFEYVGNLSKG-SYFLPGLALTDNSND-MKVYENKMKGPAHGDELAYIFEPLD-NEGKSMSGA------------VSDSDAKVRDNFVDLISKFAHSLN--GEEN--------NTKTNLMGLQPYSEEN-DQFLKIND-GI--KT------DKGFR--------------------------------------------------FCQMGLWGGMADRLTGA-L---CK------------NLIGDLLSKLP--------IP------LPVDKL--PVDN-PLNNLG---------------LGNLGGNK--------LPLNNLGGNK----N-------------MLVPGLL--------GR-KPT---------------------------EPPRVQQVTRRTTRGSLLGLP----------------------------------------IDF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caebe-g0mca8   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCRLRS-LF--------------LVFS-VLIFLNFLVVDAQYQNQNQ---Y------------------------------QNQNQQQNQNYVTVSCSQG----AVQGRTVDLGNDQSQLYSGQAHAFTGIPYCQAPV-GNLRFQPPQP-MNQ--------------FNTTLHDATYFRPKCPQLNAGN-------------------------------NAPTNEDCLYLNIYTPQVGT-------------------SGANLSVLVLIDGSNGFSNGGCDQSQ----EKGI----ISNLVQ-RQIVVVTLQYRIGALGFFTTYTNS---VQSNLGMLDQVQAMKWIKTEITNFGGNPNSITVAGQDDGACAVSA---HCLSP-MSQN--LFNQAIVQSGSVYS--CYNPTPAVPTNPTVQVTTPR-PMYDQPN---TGYGNA----NY-----GYQPQTTTPRSAYNSANSQYDDPSQQLAETLCNISPDQWNNGQT-QNIQNCMKNYTVDFFVNQ-----------------TPGGPNA-TWMIVRDTS---------FLPGSIDSLS--SRRPNIPIIIGTVQDEDAD---YAFKLINTGKGG---DP------GNLDNWIFDFARKNKLNQTQTNQVQDIIDR-GYGIPRNAGTVGGQPQYSNQGPGSQNQYSAQNQNQGGQVYSNPGGQNQYSNQNQNQGGQVYRDPATQNQGSQGGYSNPGYSTPGSQINNQYQGTSGGQQINNQYQYDQPQGSSQTNNQYQGT-----QYSGGVVAGQQTI-YSNPGGQNQYSTQNQNQPGQTRQYDQNGQIVYSNPGSQTNNQNQ-----------------------------------YSN-SGYGNQNQQSTQNQGGTYSNPGYSNQYGNQFQNNGMYTNVTQFSNVNNNYGYQRDQGVQNNRNGNNYPGMVNGNGNGVTDYSQ-LRTISQ-----IASDQ--STSLTTTQIQSYMQN-GARHVRVYQFTHVSEVGRN---T------VPDT-------GSNWKPVFKGQDMFFITMSET-IWTNS---------------NYTPQDRQVANQMGQRWSDFVKTGQVAN-------------------WDTTNQQN-YNYCNLNT-QA--SQ------QAQYG--------------------------------------------------QQARRVFQDQVNPIVQTAQ----N------------NYALANNQSVP-YP-----------SAQ-SGSQIS----------------------------RTPGQA-----QA---QYTSGANG----S----------------SNFHI-----------------------------------------------------------------------------------------------SFQVNSFPFNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caebr-a8y3e3   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQNQNQQSNYVTVSCSQG----AVQGRTVDLGNDQSQLYSGQAKAFTGIPYCQPPV-GNLRLQPPQP-LNQ--------------FNSTLQDATYYRPKCPQLNAN---------------------------------GATNEDCLYLNIYTPQVGN-------------------TTANLAVLVIIDGSNGFSTGGCDQNQ----EKGI----ISNLVQ-RQIVVVTLQYRIGALGFFTTYTQS---VQSNLGMLDQVQAMKWIKTEIVNFGGNPNQITVAGQDDGACAVSA---HCLSP-MSQN--LFNQAIVQSGSVYS--CYNPTPAVPTNPNVPVTTPR-PSYDQPN---QGYGNA----NY-----GYQPETTTARSSYNSANAQYDDPSQQLAETLCNISPDQWNSGQT-QNIQNCMKNYTVDFFVNQ-----------------QPGGPNA-TWMIVRDTS---------FLPGSIDSLT--QKRPNIPIIIGTVQDEDAD---YAFKLINSGNGG---NP------ENLDNWIFDFARKNKLNQSQTGQVQNIIAN-NYPLGGNN----------------------------------------------------------------------------------------QNQANNQYQYDQR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SATQTNNQASDQ--STSLTTTQIQSYMQN-GARHVRIYQFTHVSEVGRN---T------VPDT-------GANWKPVFKGQDMFFITMSET-IWSNS---------------NYTPQDRQVANQMGQQWSDFVKTGNVAN-------------------WDTTNQQN-YNYCNLNS-QP--TQ------QIQYA--------------------------------------------------PQARRVFQDQVNPICQTAQ----N------------NYALANNQSLP-YP-----------SATQGTSQVS----------------------------RTPGTA-----QA---QYTSGANG----G----------------SNFHI-----------------------------------------------------------------------------------------------SFQVNSFPFNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caeel-Y75b8.3  	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M--------------AVRR-LL---FLTLFSA-FSNV-SNAQY------------------------------QNQNQNQQSNYVTVSCSQG----SVQGRQVNLGNDQSQLYSGQANAFTGIPYCQAPV-GNLRLQPPQP-LNQ--------------FNTTLHDATYFRPKCPQLNAG---------------------------------GPTNEDCLYLNVYTPQAGN-------------------TNANLSVLVLIDGSNGFSNGGCDQNQ----EKGI----ISNLVQ-RQIVVVTMQYRIGALGFFTTYTNS---VQSNLGMLDQVQAMRWIKTEIVNFGGNPNQITVAGQDDGACAVSA---HCLSP-MSQN--LFNQAIVQSGSVYS--CYNPTPAVPTNPQVQVTTPR-PMYDQSN---TGYGNAGYQNNY-----GYQPQPITSTSSYNSANAQYDDPSQQLAQTLCNISPDQWNNGQT-QNIQNCMKNYTVDFFVNQ-----------------QPGGPNA-TWMIVRDTS---------FLPGSIDSLT--TRRPNIPIIIGTVQDEDAD---YAFKLINTGKGS---DP------NNLDDWIFDFARKNKLNQTQANQVSNIISN-NYGVNTG-A-----------------------------------------------------------LGQQGAQVNSQYQG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGTGQQIASDQ--STSLTTTQIQSYMQN-GARHVRVYQFTHVSEVGRN---T------VPDT-------GANWKPVFKGQDMYFITMSET-IWTNS---------------NYTPQDRQVANQMGQRWSDFVKTGNVAN-------------------WDTTNQQN-YNYCNLNT-QA--TQ------QAQYG--------------------------------------------------QQARRVFQDQVNPIVRIAQ----N------------NYAMANNQSIP-YP-----------SAS--GSQIS----------------------------RAPGTA-----QA---QYTNNANG----G----------------SNFHL-----------------------------------------------------------------------------------------------TFQVNSFPFNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caeel-zk994.1  	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVYQSLFF-----------------------ILLYFVD-------------------------------------------HMPSA-------KIR-ITNG----VIEGRELTATYSLYGN--QTSVVFLGIPHIEPPV-GKLRFRKPKPYRN---------------TWNNTLETKEFKPTCFRNFV-----AAD--------------------------GSTSEDCLYINVYSNKYCI-------------------ENKNCSVMVVVPS-GLVQSHGSF--FNDTIINN-------FVGQNRNIVVVTVPYRLGIFGSPNLPGNVKNILEKNLMLYDVIEGCNWVDREIGNFGGDSSKITYFGHRSGATIGAI---LSLLP-ESEN--LFHQMILMSTPLYMQSKTA--NS---------KSFL----------------------------------------------------KVVKQVGCDESI-------ENVDIIECMRKVRAENFVDT-HNQLNEE-----------NEDS---LNFVIDGVLLRDEPRRILESGNFK---------KIPLLIGTVPHEVL-YTRYMIDKEN-GIK-----------------------MK----------ELLELCE-----------------------------------------------------------------------------------------------------LFGFV----------------------GAYEK-------------------------------------------P--Y---------------------------------------------------------------------------------------------------------------------------GFVEQ----CV-----EFYMKN--STT-----------A-TFLDDYIF-HVPTS---------------------------YLA------------------------R------------KHSSE----------KPVYLFVNYGAPYGD-----------------EWSKLNPKI-MKYYDIDFNDK-Y---EMAGMRYGFH--------------------------------------------------EKSFEFWDDTAKEYGGVFT------------------FSNDQPKSFDTFPVWEFAKLKNYVKTGSGA--H----KIPKE-------------------------IEKFIAHK-KNEYDVRMKN----SI-----YLQK-IQM--DPSVIPV----------NYF----FLIECN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caeja-h2wkl2   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRWFFVLLICSI----------------------------------------IAAQQQQNSNYVTVNCSQG----PVQGRQVDLGNDNSQLYSGQANVYTGIPYCQPPV-DNLRFQPPQP-LTT--------------FNTSLLNATYFRPKCPQLNAG---------------------------------APTNEDCLYLNIYTPQSAT------------------SSSTNLSVLVFIDGSNGFTNGGCDQSQ----EKGI----ISNLVQ-RQIVVVTLQYRIGALGFFTTYTNT---VQSNLGMLDQVQAMTWIKSEIVNFGGNPNQITVAGQDDGACAVSA---HTLSP-MSQN--LFNQAIVQSGSIYS--CYNPTPAVPTNPTVYTTTPR-PMYDQPN---TGYGNAGYQGSY-----DYQPQSSTTPSPYNSANAQYDDPNQQLAATLCNISSADWNDGQT-QNVQNCLKNYTVEFLWKS-----------------TTGSVQN-Q-------------------------------IPN---------------------------------------------QNFN----------------------------------------------------------------------------------------------------------------------SQQANNQYQNNG----------YN-TNTTSSQYNGGYLR-----------------------------------------------------------------------------------------------------------------------------------------------------------DQPISMQNSNGITDFSQ-LRKISQ-----ISSDQ--STSLTTTQIQSYMLN-GDRHVRIYQFTHVSEVGRN---T------VPDT-------GANWKPVFKGQDMYFITMSET-IWSNS---------------SYTAQDRQVADQMGQRWSDFVKTGQVAN-------------------WDTTSQQN-YNYCNLNT-QA--TQ------QAQYG--------------------------------------------------QQARQVFQDQVNPICQVRF----H------------SSPSIFLFYLF-CPCLLRRQLL-LISDNQCGVLL-----------------------------RLPPEN----------QFTTSLA-----I----------------IIYHQATM--H-----------------------------------------------------------------------------------------TVVCFIFPLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
caere-e3mft5   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWSPRSSPI--------------FIFS-VL---FLLVVDAQYQNQNQQQQY-------QNQNQ-------------NQNYNQNQQGGQQSNYVTVSCSQG----AVQGRTVNLGNDPNQLYSGQANAFTGIPYCQPPV-GNLRLQPPQP-LTQ--------------FNTTLHDATYFRPKCPQLNAN---------------------------------GATNEDCLYLNVYTPQAGN-------------------TMANLSVLVLIDGSNGFANGGCDQSQ----EKGI----ISNLVQ-RQIVVVTLQYRIGALGFFTTYTNS---VQSNLGMLDQVQAMRWIKTEITNFGGNPNSITVAGQDDGACAVSA---HCLSP-MSQN--LFNQAIVQSGSVYS--CYNPTPAVPTNPTVQVTTPR-PMYDQPN---TGYGNA----NY-----GYQPQTTTPTSSYNSANAQYDDPSRQLAETLCNISADQWNNGQT-QNIQNCMKNYTVDFFVNQ-----------------QPGGPNA-TWMIVRDTS---------FLPGSIDSLT--SKRPNIPIIIGTVQDEDAD---YAFKLINTGKGS---DP------NNLDNWMFDFARKNKLNQTQSNQVQNIIAN-NYPGLQMTT-----------------------------------------------------------QGPQANQVNNQYQGTGQQVNNQYQTNPNGQQVNNQYQYDQGNSGQQTNNQFQGVQPGSQQYFGGVVAGQQTTTYQNPGNYQ-NQNQNQ------------NQYNYRNPGTYSPNQNQQSTQNQYGGINQNQYSNQNQQAGPTRQYDPTYQNQYSNQQQYGGQQGATQTNNQQQYG--SQGSQTSNQYQNNGIYTNVTQYSNVNNNYGVGGGLQR--DQ-QTATGLQMTGNGNGITDYSQ-LRTISQVRDNQIASDQ--STSLTTTQIQSYMQN-GARHVRIYQFTHVSEVGRN---T------VPDT-------GANWKPVFKGQDMFFITMSET-IWTNS---------------NYTPQDRQVANQMGQRWSDFVKTGQVAN-------------------WDTTNQQN-YNYCNLNT-QA--TQ------QAQYA--------------------------------------------------PQARRVFQDQVNPICQTAQ----N------------TYAMSNNQSLP-YP-----------SSS--GSQIS----------------------------RTPGTA-----QA---QYTSGANG----A----------------SNFHI-----------------------------------------------------------------------------------------------TFQVNSFPFNG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
closi-h2ku15   	----------------------------------------------M----------EGI-----------------------------AQSSRGA-------------------------DADNKFVNQSLWD--EDTYGRSPS-------VSDLRVGGLRRR-------VSSACCLNV--------------FLLLALLIAIAVIM---YF--------------------L---ISPISGRTR---PPVKS----------VVSTFCG----IVQGT----------ESN-GVVSFLGLPYALPPL-GQYRFKRPVE-LTTTRLCAQAWATNNFSANTNSYNATVYKSSCLQLSPVT------------------------------DKVIGNEDCLYLNVFVPAMAL----------------TSSKTELRPVIVVLNG-LFFTYGGASGLP----VSQGQQPQPRTVEL-VDAIHVTLNYRIGPLGFLMHPET----KEANIGLYDQLAALRWVRNNIGAFGGDAARVTLFGYGSGATCALA---LAFSS-LGQN--LFDNLWISAPAVRK--PHCSLQE----AVENSRR-------L----------------Y-----SCEP---------G-------------STRPCS-------NGL-LADPKDIVRLWNWARIESWMKDTLFSL---PSFAQIQGGAEQ--DWVDRILIV-DHEM-IDPKRWYRPIY--------HLSTVLGQTAHETAL---FVSPITVPFWDESFYRRYLINTLTSGTKIGQDM---------IDQYLIVSNKT-T-YCSH----------------------------------------------------------------------------PSSSNS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGFDVEARMT-----GLITDA--RCTCPLAETVQQLASSHGNFVYHYYLFGQHRRFDP-YSF-----------------TSFVSLSFHGWDGMVYLRGYT-THPDYIQSMLDQ-----NDHDHMEDLGRQSDLLNTVMHEFSRTGRILS-------------------WNPVEPGNAPVNLIENG-AV--CT------PPKFV--------------------------------------------------EERCRLWKLVTNGNPLD------L------------AWRS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
culqu-b0wiy0   	------------------------------------------------------------------------------------------------------------------------MLILLVIIIPLFA----PTI----------S------GGGGN----------------------------------------SDENDS---------------------------------------------VKKT----TSRVVHTKYG----SVSGT----IEHLEGRHLDPV