MSA from Cobalt (Ncbi)
Cobalt
Color code Main amino-acide (aa) at this position Non majority aa at this position 50% conservation Catalytic site Catalytic site in alignement
Position ....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....
9acto-b4v9e5 -------------------------------------------------------------MRKTLGWLLS----------LVVLIGTMGAAGFTA----------------------------QA-------------------------------------------------------A----------TA-------------------------------------------AGP-------------AAGADIKDQILAVPGMSLVEEKP--Y--PGYRFFVLNYTQPVDHKNPWKGTFQQRLTLLHKDTSRPTVFFTSGYNV--NTSP-RRSEPTTIVDGNQVSLEYRFFTPSRPDPANWAN-LDIWQAASDQHRIFTALK-KIYTKNWLATGASKGGMTATYYERFYPRDMDGVVAYVAPNDVVNNEDSAYDRF-FTKVGT--------KECRDKLNAVQREALVRRDALEVKYAATATQNGWTFN-TVGNLDKAYEAVVLDYVWAFWQYSL-LSDCGG---IPT-AATATDQEIWDSIDTISGFS---AYTDQGLETYTPYYYQAGTQLGAPTIK--LPHLG-SLSRYGYQGP-----RNFVPRDI-----PMSFQPKAMTDVDNWVRENANQMLFVYGQNDPWGAEPFHLGYGV--RDSYVMIAPGA-NHGASVS-KLLDGERTLATAKILQWAGVAPAATLADTG---------RATPLAKPDAR--LDQRELERE-----------------------PQLRP---- =====>
9acto-b4vfi7 -----MRSGR----GMSSPMGGRRHPRSGDPPAF---------------RVRLPGGMENT------MRRLL----------TVVVVVLLSVTGM-------------------------------------------------------------------------------------------------------------------------------------------------T-------APVLAQPAGGDIRARVAAVPGLRLLAERP--G-APGQTVLDLAFRQPADHHRPGRGSFEQRLTLVHKSFDRPMVLYSGGYDL--GSSPQRPAEPSVLLDSNQITTEQRFFGTSRPATPDWST-LTIWQAASDHHRLITALK-TLYRGPWISTGGSKGGMTAVYHRRFYPQDVVGTVAYAAPNNVDDRDDSAYDAR-LEEVGT--------AECRAALKSAQRQALLRREAMTERYGRWAEQEKGTFR-TIGSTDRAFELAVLRLPMMFWMHQS-AGGCAS---IPA--ADASDDTLYAWIAGVTLLP---VYTDQSLEEFTPYFHQLGTQLGYAQFS--APHLEGLLRHPGVQEV-----RSYVPRDI-----PMTFEPGAMADIDRWVRRQGSSLMFVNGENDVAVAEPFRLGAGS--RDSYVFEAPQG-DHHISIA-GLRPAVAGRATAVLRRWAR-------------------------------------------------------------------------- =====>
9acto-b5hne2 -------------------------------------------------------------MRKALRWLLT----------LVVLIGTVGTAGA---------------------------------------------------------------------------------------A----------TA-------------------------------------------AEPGAQG------TGAT--ADIKDQLLAVPGMSLIEEKP--Y--TGYRFFVLDYTQPVDHRHPSKGTFQQRITVLHKDVSRPTVFYTGGYNV--STTP-RRSEPTQIVDGNQVSMEYRFFTPSRPDPADWTK-LDIWQAASDQHRIFKALK-KIYPKNWLSTGGSKGGMTATYFERFYPRDMDGVVAYVAPNDVVNNEDSAYDRF-FEKVGT--------KECRDRLNAVQREALVRREPLERKYADYAAAEGLTFT-TVGSLDKAYEAVVLDYVWGFWQYNL-LANCGDDELIPANAKTATDDQIWNSVDTISGFS---AYADQGLETYTPYYYQAATQLGAPTIK--FPHIEKKYIRYGYQPP-----RNFVPRSI-----PTKFQPYAMRDVDTWVRNNARHMLWVYGQNDPWGAERFRVDKGA--KDAYVFTAPGM-NHGANVA-GLVADQKAFATARILAWAGVPATAV-------------AAAKPLAKFDTK--LDVRDVERE-----------------------PTLRP---- =====>
9acto-d6a0p1 ---------------------------------M---------------YCRQPTSREGHPMRLWTRRRLL----------LST-ASAASTAALAA----------------------------TA-------------------------------------------------------S----------AP-------------------------------------------AHA-------LTGKPPAPDDAIVRRLGSLPGVRIVEERP--STEPGYRLFVLGLRQPVDHTDPSAGTFEQRLTLLHTSTERPTVLFTTGYGA--VLTS-RLTEPTVLLGGNQLQVEHRYFGTSLPSVHDYSH-LTVRQAADDHHRVVRTFR-RLYPGAWISTGGSKGGMASVYHRRFHPHDVDGTVAYAAPNNVDDRDDSAYLRF-LETVGT--------AADREAIRTAQRRLLLHRAELVARYEAATTAAGDTFR-IVGSADKAFEVAVLRAPFMFWQNGGSAADRAA---LPG--PDATADRLYTWLDDTAGLS---LYADAVARAYIPYWYQLATEMGYLDVP--TAHLSDLLRHPGAVEP-----RTFVPRDI-----PVRFDPDAMPDIDRWVRRSGTRLLFVNGTRDPSTAESFPP--GR--HDSRVLWVPDA-NHHTTLA-DLPAADRAEATAMLTRWAART------------------------------------------------------------------------ =====>
9acto-d6a0x6 -------------------------------------------------------------MRKALRWLLA----------LTVLIGTMSTAGA---------------------------------------------------------------------------------------A----------TA-------------------------------------------AEPEATG------T-----IDIKERLLSVPGMSLIEEKP--Y--TGYRFFVLNYTQPVDHHRPAKGTFQQRITVLHKDVARPTVFHTGGYSV--STTP-RRSEPTQIVDGNQVSMEYRFFTPSRPDPADWSK-LDIWQAASDQHRIFTALK-KIYPENWISTGGSKGGMTATYYERFYPRDMDGVVAYVAPNDVVNKEDSAYDRF-FRTVGT--------KECRDRLNAVQREALVRRAPLEKRYEAYAAENGYTFD-TIGSLDRAYEAVVLDYVWGFWQYST-LADCEQ---IPADAKNATDDEIWTSIDTISGFS---FYTDQGLSPYTPYYYQAGTQLGAPTIH--FPHIEKKYIRYGYQPP-----RNFVPRSI-----PMRFEPSAMRDIDTWVRHNARQMLFVYGENDPWGAEPFRLGHGA--RDSHVFTAPGM-NHGANVA-GLVEKEKAFATARILDWAGVAPSAVREN-----P----AAAKPLAKFDAK--LDRRGVERE-----------------------RTLRP---- =====>
9acto-d6b1e1 -------------------------------------------------------------MRTVLRWLLS----------LVVLAGAVTAQ-------------------------------------------------------------------------------------------------------------------------------------------------AGTAVAGQ-----DPARDGRDILQRLLAVKGVELVEEKP--Y--EGYRYFVLTYTQPVDHRHPKRGTFEQRFTVLHKDTSRPTVFHTSGYGV--STAP-GRSEPTRIIDGNQISLEYRYFTPSRPEPADWSE-LTIWQAASDQHRLFQALK-PVYGKKWLATGGSKGGMTATYYERFYPRDMDAVVAYVAPNDVVDSEDSAYDRF-LEQVGT--------AECRDALHAVQREALLRREPLSERYRELAEKSGATFT-TVGSLDKAFEAVVMDLAWGFWQYAD-EADCAA---VPQ-ARTATDVELFAYVDEISGWS---FYTDQGLAPYTPYYYQAGTQLGSPGIA--QPHLA-DLSRYGYQAP-----REFVPRSI-----PMRFEKHAMRDVDTWVRHHAQRMMFVYGENDPWSAEPFRLGAGA--RDSYVLTAPGA-NHGANVA-GLVPDESARATARIQQWAGVAPATAQAD-----P----ESAAPLAAYDKT--LDSLDEKLL-------------------QK-YRGGKP---- =====>
9acto-d6m5z3 -------------------------------------------------------------MRALLATLVA----------GTLTAGIAATGTATA----------------------------AA-------------------------------------------------------P----------VT-------------------------------------------APAAAGSG-----SGTADTRDIKERLLSVPGMSLIEEKA--V--SGYRYFVLGYRQPVDHRHPSRGSFTQRLTVLHKDTSRPTVMYTGGYNV--STSA-SRSEPTRLVDGNQVSVEYRYFSPSRPEPADWSK-LDIWQAASDQHRLYRALK-KIYGQHWLATGGSKGGMTATYYERYYPRDMDGVVAYVAPNDVNNAEDFAYDRF-FERVGT--------KECRDALDAVQREALIRRGPLERKYADQAKAEGWSFG-TVGTLDKAYEAVVLDLVWGFWQYSD-EADCAD---VPE-ARTVSDDDLYAYVDAISGWS---FYTDQGLDPYTPYYYQAGTQLGAPTIA--LPHLK-GLTRYGYQPP-----RNFVPRDI-----PMRFDRRAIPDVDHWVRHHARHMLFVYGENDPWGAERFRVGQGS--RDAYVMTAPGA-NHGANIA-GLAPGSRELATARVLDWAGVDAGTQAAA-----P---------LARLDKA--PAE--EPRL-------------------RP----------- =====>
9acto-d9un73 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTRDIKERLLSIPGMSLIEEKP--V--SGYRYFVLAYRQPVDHRHPSRGSFTQRLTVLHKDTSRPTVMYTSGYNV--STSA-SRAEPTRLVDGNQVSVEYRYFSPSRPQPADWSK-LDIWQAASDQHRLYRALK-KVYGRNWLATGGSKGGMTATYYERYYPHDMDGVVAYVAPNDVDNAEDSAYDRF-FERVGA--------KECRDALDAVQREALIRREPLEKKYADQAKAEGWSFG-TVGTLDKAYEAVVLDLVWGFWQYSG-EADCAD---VPD-AGTVSDDDLYAYVDAISGWS---FYTDQGLDPYTPYYYQAGTQLGAPSIS--LPHLK-GLTRYGYQPP-----RNFVPRAI-----PMRFDRRAIPDVDHWVRHHARHMLFVYGENDPWGAERFRVGPGA--KDAYVLTAPG------------------------------------------------------------------------------------------------------- =====>
9acto-d9vwk0 ------------------------------------------------------------------------------------MIGTMGTAGLTA----------------------------QT-------------------------------------------------------A----------TA-------------------------------------------AEPAAAAQAT---AGQGSAADIKDQILAIPGMSLIEEKP--Y--PGYRFFVLNYEQPVDHRQPWKGTFKQRITLLHKDVSRPTVFYTSGYNV--NTNP-RRAEPTTIIDGNQLSMEYRFFNPSRPDPADWSK-LDIWQAASDQHRLFTALK-KIYPKNWLSTGASKGGMTATYFERFYPRDMDGVVAYVAPNDVVNKEDSAYDRF-FGKVGT--------KECRDKLNNVQREALIRREPLEAKYKAAAAENGWTFN-TVGSLDKAFEAVVLDYTWAFWQYSL-LADCAT---IPD-AKTATDQQIWDTVDAISGFS---AYADQGLETYTPYYYQAGTQLGSPDIK--QPHLK-GLSRYGYQPP-----RNFVPRDI-----PMTFQPAAMADVDTWVRNNAHQMLFVYGQNDPWGAEPFHLGYGV--RDSYVMTAPGA-NHGANVA-KLQDGEKALATARILQWAGVAPAADVFRADGAAP----QPAAPLAAPDPV--LDQTDLRRE-----------------------SLRR----- =====>
9acto-d9wnu1 ------------------MHPGDVHPR-------------------------------GGRMGKALRWLLS----------LVIIVGAVGAGAGSA----------------------------PA-------------------------------------------------------A----------A---------------------------------------------------------ATPASEPDIKERVLAIPGMSFVEEQP--Y--DGYRFLVFTYQQPVDHRHPSKGTFKQRFTLLHKATDRPTVFFTSGYNV--ATTP-RRSEPTQIVDGNQVSMEYRFFTPSRPQPADWSK-LDIWQAASDQHRLYRALH-RVYGKKWLATGGSKGGMTATYYRRFYPHDMAGTVAYVAPNDVVNDEDSAYDRF-FAGVGT--------AECRTKLNAVQREALVRRDEIVARYQKWADEEKQTFK-VVGSADKAYENVVLDLVWAFWQYHL-LKDCAD---VP--ATTASTDELYKFIDDISGFS---AYTDQGLETYTPYYYQAGTELGAPTFK--TPHLDGLLRYPGIYNP-----RNYVPRDI-----PMRFKPGAMRDVDRWVRHDANRMLFVYGENDPWGAEPFRLGKGA--RDSYVYTAPGG-NHGSNIA-QLTAPEKAKATAAVQKWAGVPT-----------------SSKPLAPRDTK--LDRREVERE-----------------------PTLRP---- =====>
9acto-d9xzb4 -------------------------------------------------------------MRKALRWLLA----------LTVLIGTLSTAGA---------------------------------------------------------------------------------------A----------TA-------------------------------------------AEPEATG------T-----TDIKERLLSIPGMSLIEEKP--Y--TGYRFFVLNYTQPVDHRRPSKGTFEQRITVLHKDTARPTVFYTGGYSV--STTP-RRSEPTQIVDGNQISMEYRFFTPSRPEPADWSK-LDIWQAASDQHRIFTALK-KIYSQNWISTGGSKGGMTATYYERFYPRDMDGVVAYVAPNDVVNKEDSAYDRF-FAGVGT--------KECRDRLNGVQREALVRRAPLEKKYEAYAAENGYTFD-TIGSLDRAYEAVVLDYVWGFWQYST-VADCAD---IPADARNATDEEIWTSVDTISGFS---FYTDQGLSPYTPYYYQAGTQLGAPTIQ--FPHIEKKYVRYGYQPP-----RNFVPRSI-----DMRFQPSVMRDVDTWVRHNARQMLFVYGENDPWGAEPFRVGHGA--RDSYVFTAPGM-NHGANVA-GLVADEKAFATARILDWADVAPAKVQEN-----P----AAAKPLAKFDAK--LDKRDVERE-----------------------RTLRP---- =====>
9acto-e9uw33 -------------------------------------------------------------MRALIGRILV----------A---MGLVSL--------------------------------------------------------------------------------------------------------------------------------------------------LLVTPAN------PATAAEDDILDRLLAIEGVSLIQEKP--V--TGYRYFVLSFTQPVDHRRPDGDTFQQRFTVLHKDTARPTVFHTSGYNV--STNP-GRSEPTRIVDGNQVSMEYRFFTPSRPDPADWDD-LDIWQAASDQHAIFKALK-PIYSANWLATGGSKGGMTATYFERFYPRDMDGIVAYVAPNDVVNREDSAYDEF-FATVGT--------EDCRDRLNGVQREALVRREALKAKYADLAAAEGYTFD-TVGSLDAAYEMVVLDYVWAFWQYAG-TSQCSN---IPADAATATDQAIWDSIDYYSGFS---FYTDQGLSPYTPYYYQAGTELGAPTIG--FPHIEDELIRYGYQPP-----RSFVPRDI-----DMRFDPSAMRDVDSWVRKHAHQMLFVYGEADPWGAERFRPGFFA--TDSYVFTAPGM-NHGANVA-GLVADERELATARILEWAGVATAAVEAD-----P----TKAKPLAAYDAK--LDKRDLRRE-----------------------PTLR----- =====>
9bace-b3c8j8 ------------------------------------------------------------MK-HMHIRYAALLL--F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLSASVSSFAQTVLEQKISAISAIKEIRPLET---SEFSEKYVTYFTQPLDHCHPEKGSFRQRVIVSHVGFDRPTVIVTEGYGAAYALRSQYREELSKLLNANMIFVEYRYFLESTPEPKDWQY-LTAENSADDLHAITTAFK-NIYPGKWIATGISKGGQTTLLYRTFYPDDVDISVPYVAPLCYGV-EDGRHEPFLH-KVST--------PENRKIIEDFQLEALKRKATLLPRFEKYCTEKNYSFR---APIEEIYDYSVLEYSFALWQWGTP---ISS---IPA--TTASDDEIFSHLLAISEPGYFTAD-----SPNASFFVQAARELGYYGYD--VQPF---KQYLSIQSSEDYLHRLMLPEELKD----MPFDKTLSKKITKFLKKQDPKMIFIYGQNDPWTAAGVTWLKNK--KNIHVFIQPNG-SHLARIS-TLPEKEKKEVMELIKQWLK-------------------------------------------------------------------------- =====>
9bace-b6vyn8 --------------------------------------------------------------------MLWAILAVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQMTQAAAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYAAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDQKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNKSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKNQLLPMFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TDADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRNYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGNDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
9bace-c3q6p6 -------------------------------------------------------------MKHTHSFMLWAILAVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQITQATAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYAAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDQKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKNQLLPMFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TDADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRDYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGNDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
9bace-c3rgi3 -------------------------------------------------------------MKHTHSFMLWAILAVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQITQATAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYAAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDQKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNKSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKNQLLPMFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TDADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRNYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGNDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
9bace-c6z556 -------------------------------------------------------------MKHTLSFMVWAILAVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQMAQAAAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDEKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKSRLLPIFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TNADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRDYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
9bace-d1kae9 -------------------------------------------------------------MKHTHSFMLWAILAVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQITQATAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYAAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDQKWIATGISKGGQTTMFYRTYFPDDVDISVPYVVPLNQSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKNQLLPMFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TDADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRDYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGNDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
9bace-d2f268 ------------------------------------------------------------MK-NLRNYYAAFLL--F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLFVSAAAPAQTDLQQKLGRISAITETRPLES---TRFSEKYVTYFTQPLDHRHPEKGSFRQRVIVSHVGFDRPTVIVTEGYGAAYALNPKYREELSELLDANMIFVEYRYFLESTPEPKDWQY-LTAENSADDLHAVRNAFK-SIYPGKWIATGISKGGQTTLLYRTFYPDDVDISVPYVAPLCYGA-EDGRHEPFLR-KVST--------PEDRKRIEDFQLEVLKRKAALLPRFEKYCNEKGLKFR---APVEEIYDYCVLEYSFALWQWGTP---VSS---IPA--TTASDDEIFAHLLDISNPDYFIAD-----SPTASFFVQAAHELGYYGYD--TKPF---KKYLSIQSSKDYLHRLMLPEELKD----MPFDKTLSKKITKFLKENDPKMIFIYGQNDPWTAAGVTWLKGK--KNIHVFVEPGG-SHRARIG-TLPDVQKQEAISLINKWLQE------------------------------------------------------------------------- =====>
9bace-e1yn39 -------------------------------------------------------------MR-----RTFNF-LLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------FFLSVMTVMAAPGDLQEKLAALKGISGIEKLQS---DHYPEKYVVRITQQVDPKDPAAGTFTQRVIVGHVGYDRPTIIVTEGYGAAYALNPKYQEELSKLLNANLVFVEYRYFLESTPEPKNWDY-LTAENSAYDLHNVRNTFK-QIYPEKWISTGISKGGQTTMLYRAFFPDDVDFSVPYVGPLCKGV-EDGRHEPFLR-KVGT--------KAERKRIQDFQLEVLKRKSDMLPLLESYCKNKNLTFR---IPMPEVLDYCVLEYSFALWQWGTS---VST---IPS--KSADDQALFDHLMEISGPDYFAEN-----QPNISFFVQAARELGYYGYD--VKPF---KKYLTIDSAHGYLNRIMLPGELVD---KVDFRPALYHKIYNFLKDNDPKMIFIYGEIDPWSAAMVPAFKGK--KNEQIYIQPRG-SHRARIG-NMPEDMKERILTQMNKWLAE------------------------------------------------------------------------- =====>
9bace-e2nl22 ------------------------------------------------------------MK-NMHIRYAALLL--F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------VLLSASASSFAQTVLEQKINAISAIKEIRPLET---SEFSEKYVTYFTQPLDHRHPEKGSFRQRVIVSHVGFDRPTVIVTEGYGAAYALRSQYREELSKLLNANMIFVEYRYFLESTPEPKDWQY-LTAENSADDLHAITTAFK-NIYPGKWIATGISKGGQTTLLYRTFYPDDVDISVPYVAPLCYGV-EDGRHEPFLH-KVST--------PENRKIIEDFQLEALKRKATLLPRFEKYCSEKNYSFR---APIEEIYDYSVLEYSFALWQWGTP---ISS---IPA--TTASDDEIFSHLLAISEPGYFTAD-----SPNASFFVQAARELGYYGYD--VQPF---KQYLSIQSSEGYLHRLMLPEELKD----MPFDKTLSKKITKFLKKQDPKMIFIYGQNDPWTAAGVTWLKNK--KNIHVFIQPNG-SHLARIS-TLPEAEKAEVMELINEWLK-------------------------------------------------------------------------- =====>
9bace-e5umz3 --------------------------------------------------------------------MVWAILAVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQMAQAAAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDEKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKSRLLPIFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TNADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRDYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
9bace-e5vbl4 ------------------------------------------------------------MK-NLRNCYAAFLL--F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLFVAAAAPAQTDLQQKLGRISAITETRPLES---TRFSEKYVTYFTQPLDHRRPEKGSFRQRVIVSHVGFDRPTVIVTEGYGAAYALNPKYREELSELLDANMIFVEYRYFLESTPEPKDWQY-LTAENSADDLHAVRNAFK-SIYPGKWIATGISKGGQTTLLYRTFYPDDVDISVPYVAPLCYGV-EDGRHEPFLR-KVST--------PEDRKRIEDFQLEVLKRKAALLPRFEKYCNEKGLKFR---APVEEIYDYCVLEYSFALWQWGTP---VSS---IPA--TTASDDEIFAHLLDISNPDYFIAD-----SPTASFFVQAARELGYYGYD--TKPF---KKYLSIQSSKDYLHRLMLPEELKD----MPFDKTLSKKITKFLKENDPKMIFIYGQNDPWTAAGVTWLKGK--KNIHVFVEPGG-SHRARIG-TLPEEEKKQVMELINEWLKQ------------------------------------------------------------------------- =====>
9porp-a7ah55 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTVAFAGNAQELQKKLEGLKGISGIEKLES---DHYAEKYLVRITQPVDHKNPAAGTFTQRVIVAHVGFDRPTILVTEGYGAAYALNPRYQEELSKLLDANMVFVEYRYFLESTPTPCNWEY-LTAENSAYDLHNVNQTFR-ELYTGKWVSTGISKGGQTTCLYRAWFPDDVDFSVPYVAPLNRGV-EDGRHEPFLR-KVGT--------KKDRQKIEAFQIEILKHKDEIVPMLEKFCKDKKLEFR---IPIAEVLDYCVLEYPFALWQWGTP---TSV---IPP--LTSDAKTLFYHLVDISGPDYFAEN-----QPNISFFVQAARELGYYGYD--TKPF---RKYLTIDSSRGYLNRIMLPKELVD---KVEYRPELYHKVYDFLRDNDPKMIFIYGEVDPWSATRVPIFKGK--VNEQVYIQPGG-SHRARIG-NMPEDMKEKILTQINKWLAE------------------------------------------------------------------------- =====>
9porp-c7x4t4 -------------------------------------------------------------MR-----RTFNF-LLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------FFLSVMTVMAAPGDLQEKLAALKGISGIEKLQS---DYYPEKYVVRITQQVDPKDPAAGTFTQRVIVGHVGYDRPTIIVTEGYGAAYALNPKYQEELSKLLNANLVFVEYRYFLESTPEPKNWDY-LTAENSAYDLHNVRNTFK-QIYPGKWISTGISKGGQTTMLYRAFFPDDVDFSVPYVGPLCKGV-EDGRHEPFLR-KVGT--------KAERERIQDFQLEVLKRKSDMLPLLESYCKNKNLTFR---IPMPEVLDYCVLEYSFALWQWGTS---VST---IPS--KSADDQALFDHLMEISGPDYFAEN-----QPNISFFVQAARELGYYGYD--VKPF---KKYLTIDSAHGYLNRIMLPEELVG---KVDFRPALYHKIYNFLKDNDPKMIFIYGEIDPWSAAMVPAFKGK--KNEQIYIQPRG-SHRARIG-NMPEDMKERILTQMNKWLAE------------------------------------------------------------------------- =====>
amymu-d8hu87 -------------------------------------------------------------MRRLFTAGAV----------LLALAGL-----------------------------------------------------------------------------------------------------------------------------------------------------------------APAAAAAPDIKAQLQRIPGLTIVSEDA--A-PAGFRFFKLTYTQPADHRHPGAGTFQQRFTLLHRDFAAPTVAFTSGYNV--SGSP-NRSEPTQIVDGNQLSMEYRYFTPSRPEPENWAKQLTIWQAAADEHRAVQAFK-AIYPGKWLATGGSKGGMTATYFRRFFPDDVDATIPYVAPNDVIDPID-VYNRF-LSRVGD-------DPACRDALKAIQRDALKRRDELGPIAAADAAQRGLTFS-IVGSADKSLEISVIDSYFAFWQYQK-QADCAT---VPP--AGAPAADVYAWYEKVESLN---TYSDQDLAPYIPYYYQAAVQLGSPEAY--DGYLRDLLRYPGADQP-----KTFVPASIRL----PRFDYLAMPDIDFWVKSRGTRLLFVYGANDPWGAEPFELGFGS--RDSYRYYVQGG-NHGSKIA-QLAPPDAAAATATVRRWAGLPPVAPLAA-----R----SAPAGFPDFDTD--LTPRARL---------------------------------- =====>
bacfn-q5lhv2 ---------------------------------MQYDYLEALVKDLSLYKIK-----TEINMKNLRIWQTLSLW--L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------VLLVTSLPLSAQTALLEKLGKIADITGTQPLES---TEFVEKYVAYFTQPLDHRHPEKGSFSQRVIVSHVGFDRPTVMVTEGYGASYALGANYREELSKLFNTNMIFVEYRYFLESTPTPKDWQY-LTAENSAEDLHAVREAFR-SIYPGKWIATGISKGGQTAMLYRTFFPEDVDISVPYVAPLCYGV-EDGRHEPFLK-MVST--------PEARKKIEDFQLEVLKRKPTLLPRFEKYCAGKKYKFR---APVEEIYDYSVLEYSFSIWQWGTP---VDQ---IPA--VTASDDELFKHLLAISEPSYFEEE-----GANTSFFVQAARELGYYGYD--IRPF---KKYLTIKTSKDYLKRLMLPEELGD----MKFDKTLSRKIIHFLKNNDPKMIFIYGQNDPWTAAGVTWLKGK--KNIHVFVEPNG-SHLARIG-TLPQKEKEEAIGLIKKWLEE------------------------------------------------------------------------- =====>
bacfr-q64yv4 ---------------------------------MQYDYLEALVKDLSLYKIK-----TEINMKNLRIWQTLSLF--I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LLLSITLPLSAKSDLLTKLNTITLIIRTQSLET---SLFAEKYLLRFKQPLDHSHPEKGSFSQRVIVAHVGYDRPTLMVTEGYGAARSLNPGYYEELSKLFNTNIIAVEHRYFLESTPKPKDWKY-LTAWNSARDLHAIREAFR-SIYPGKWIATGISKGGQTAMLYRTYFPDDIDITVPYVAPLCRSV-EDGRHEPFLR-TVAM--------PDDRQKVEDFQMEVLKRKAALLPHFKKYCSVRKLQFR---APVEDIYDYTVLEYSFSLWQWGIP---VSR---IPS--VSASDKELFDHLVAISAPSYFVKE-----GSNTSFFVQAARELGYYGYD--IRPF---REYLSIGTSKDYLRRLMIPEELAD----MEFDETLSYKITRFLKENDPKMIFIYGQYDPWTAAGVTWLKGK--KNIHVFVQPKG-SHMARIH-TLPQKEKEEAIGLIKKWLEE------------------------------------------------------------------------- =====>
bacse-b0ntn3 --------------------------MVVLSPFLSGRQQPEEENRLSLSPIT-----NKHIMKDLRTRHTALLL--F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLLASVSLSAQTGLQQKLSEISAITETQPLES---TEFSEKYVTYFTQPLDHRHPKKGSFRQRVIVAHAGFDRPTVIITEGYGAAYALKPQYREELSRLLNANMVFVEYRYFLESTPEPKDWRY-LTAESSADDLHAVTTAFK-NIYPGKWIATGISKGGQTALLYRTFYPDDVDVSVPYVAPLCYGT-EDGRHEPFLK-KVST--------DEDRKRITDFQLEILKRKAALLPLFEKYCTEQEYKFR---APIEEIYDYSVLEYSFALWQWGTP---VGS---IPL--PTATDAELIAHLLAISDPSYFTTD-----STNASFFVQAARELGYYGYD--TRPF---KKYLSIKSGKGYLHRLMLPEELKD----MPFDKTLSRKIKGFLQKNDPKMIFIYGENDPWTAAGVTWLKEK--KNIHVFIQPGG-SHLARIS-TLPEKEKEEVMKLLNEWLR-------------------------------------------------------------------------- =====>
bact6-e6sqv4 ------------------------------------------------------------MTKNHKLRTTLFLA--A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LFLLSTALHAQQGNLTEKLKEIPAITETRPLES---TEFSEKYVTYFTQPLDHRHPGQGSFRQRVIVSHVGFDRPTVIVTEGYGASYALHPRYREELSRLLNANMIFVEHRYFLESTPEPRDWQY-LTAENSADDLHAVRNAFK-SIYPGKWIATGISKGGQTALLYRTFYPDDVDISVPYVAPLCHAV-EDGRHEPFLR-KVST--------AENRKKIEDFQLEVLKRKATLLPHFEQYCRKHELKFH---APVEEIYDYSVLEYSFAFWQWGTP---ARS---IPA--VTASDSELLEHLLTISSPDYFIAD-----SPTTSFFVQAARELGYYGYG--VKPF---KKYLSIKSSKEYLRRLMLPEELKD----MPFDKTLSRKITKFLKENDPKMIFIYGENDPWTAAGVTWLKGK--KNIHVFMEPGG-SHKARIN-TLPESDKKKVMELIDEWLKQ------------------------------------------------------------------------- =====>
bacth-BT2436 ------------------------------------MCKKVRANDYLCEKIN-----TQMLMKHIRIPLFVWFSIVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LIAVAPVSLSAQESFIQKIEKNKSVSGIKLLDT---SRFPEKYVMYLTQPLDHRHPEKGSFRQRVIVGHVGYDRPTVIVTEGYGAGYALRPTYREELSELFDANMIFVEHRYFLESTPEPCDWQY-LTAENSAEDLHAVTTAFK-TLYPGKWISTGISKGGQTSLLYRVFFPDDVDVSVPYVAPLCYAR-EDGRHEPFLR-RVGT--------EADRKKIEDFQLEVLKRKARLLPRFEKMCTEKNYTFR---APLEEIYDFCVLEYSFSIWQWGTD---IRS---IPE--TSASDDTLLDHLLAISGPSYFIVD-----SPTLSFFVQAARELGYYGYD--IAPF---KPYLSIKTSKDYLRRLMLPEDMRK----MKFDKTLSNKIVRFLKKNDPKMIFIYGQNDPWTAAGVTWLKNK--KNIHVFVEPGG-SHLARIG-TMSEDQKQKVMSLLRGWLEE------------------------------------------------------------------------- =====>
bacun-a7v2t5 ------------------------------------------------------------MK-NLRNCYAAFLL--F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLFVSAAAPAQTDLQQKLGRISAITETRPLES---TRFSEKYVTYFTQPLDHRHPEKGSFRQRVIVSHVGFDRPTVIVTEGYGAAYALNPKYREELSELLDANMIFVEYRYFLESTPEPKDWQY-LTAENSADDLHAVRNAFK-SIYPGKWIATGISKGGQTTLLYRTFYPDDVDISVPYVAPLCYGA-EDGRHEPFLR-KVST--------PEDRKRIEDFQLEVLKRKAALLPRFEKYCNEKGLKFR---APVEEIYDYCVLEYSFALWQWGTP---VSS---IPA--TTASDDEIFAHLLGISNPDYFIAD-----SPTASFFVQAARELGYYGYD--TKPF---KKYLSIQSSKGYLHRLMLPEELKD----MPFDKTLSKKITKFLKENDPKMIFIYGQNDPWTAAGVTWLKGK--KNIHVFVEPGG-SHRARIG-TLPEEEKKQVMELINEWLKQ------------------------------------------------------------------------- =====>
bacv8-a6l0d9 -------------------------------------------------------------MKHTLSFMVWAILAVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQMAQAAAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYTAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDEKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKSRLLPIFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TNADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRDYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
bacvu-d4vbw6 --------------------------------------------------------------------MVWAILAIL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LPLQMAQAAAPPTELQKRLQNLPDISDIKPMQS---DAYPEKYVFFINQLLDPHHPEAGNFKQRVILSHVGFDRPTVLVTEGYAAHYATHPRYQEELSKLFNANLVFVEYRYFGESMPKPCNWDY-LTVENSLYDLHHVTTTLK-QLYDEKWIATGISKGGQTTMFYRTYFPDDVDISVPYVAPLNQSL-EDGRHEPFIANKVST--------PENRKRVENFQLEVLKRKSRLLPMFEKYCSDKGYTFR---IPIAEVYDFNVLEYSFALWQWGTP---VNK---IPE--TNADDHTLFKHFMAICEPDYFSEQ-----SPYPSFNVQAAKELGYYGYD--IKPF---KKYLTIKSSRDYLHKVMLPPELSN----LKFDKTLYNKVVKFLKENDPEMIYIYGGDDPWTASGVTWLKNK--KNIKVYVLPGG-SHTTRIG-SFDTDTQEEIKTQINAWLNKE------------------------------------------------------------------------ =====>
hahch-q2sae5 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDMLKKPPYSLFFAFILSLFLSSAGYAEQAPAQDILEYLNGVQGMEAEELD---NPPDGYRYILIRYEQPVDHDNPAMGTFKQRMVLLHKSAEAPMVLATNGYNI--SVST-YRYNLTKVLNASQLKIEHRYFAESRPDPLDWQY-LTIKQAATDHHRIVQAIR-PFYSGKWISRGASKGGMTAMYHRRFFPNDVDGTV |
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