MSA from Cobalt (Ncbi)
Cobalt
Color code Main amino-acide (aa) at this position Non majority aa at this position 50% conservation Catalytic site Catalytic site in alignement
Position ....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....790..5....800..5....810..5....820..5....830..5....840..5....850..5....860..5....870..5....880..5....890..5....900..5....910..5....920..5....930..5....940..5....950..5....960..5....970..5....980..5....990..5....1000.5....1010.5....1020.5....1030.5....1040.5....1050.5....1060.5....1070.5....1080.5....1090.5....1100.5....1110.5....1120.5....1130.5....1140.5....1150.5....1160.5....1170.5....1180.5....1190.5....1200.5....1210.5....1220.5....1230.5....1240.5....1250.5....1260.5....1270.5....1280.5....1290.5....1300.5....1310.5....1320.5....1330.5....1340.5....1350.5....1360.5....1370.5....1380.5....1390.5....1400.5....1410.5....1420.5....1430.5....1440.5....1450.5....1460.5....1470.5....1480.5....1490.5....1500.5....1510.5....1520.5....1530.5....1540.5....1550.5....1560.5....1570.5....1580.5....1590.5....1600.5....1610.5....1620.5....1630.5....1640.5....1650.5....1660.5....1670.5....1680.5....1690.5....1700.5....1710.5....1720.5....1730.5....1740.5....1750.5....1760.5....1770.5....1780.5....1790.5....1800.5....1810.5....1820.5....1830.5....1840.5....1850.5....1860.5....1870.5....1880.5....1890.5....1900.5....1910.5....1920.5....1930.5....1940.5....1950.5....1960.5....1970.5....1980.5....1990.5....2000.5....2010.5....2020.5....2030.5....2040.5....2050.5....2060.5....2070.5....2080.5....2090.5....2100.5....2110.5....2120.5....2130.5....2140.5....2150.5....2160.5....2170.5....2180.5....2190.5....2200.5....2210.5....2220.5....2230.5....2240.5....2250.5....2260.5....2270.5....2280.5....2290.5....2300.5....2310.5....2320.5....2330.5....2340.5....2350.5....2360.5....2370.5....2380.5....
9dipt-q19q11 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKHRLHR------------EPP-------------------L----DKDAIFNA---LEVVE-TKWIE----QP---------LNH--F-DPQ----------------D-HRVWQM--------------------------RYM-ENR-EFL-------------------------------------------------------QDGG-PIFIYVGGEWT--ISEGW-------------------------------LRSSHFH-Y-MAE-----QLNGTLYYTEH-----------------RYYGES--H------------------------------PTED-------------LT------------V------DNL-RF---LNIDQA---------------LADLAHFITHIKQ--TTP--------------------------------------------ELQ-N--SGVILIG----------ASYSATMVTWF-----------MQKYP--------HL--AR-----------------GAWSS-SAPLEA---KV-------------------D-FV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9eugl-b6dt83 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRA------------RQGSVYK-DS---------VMA----------LQW-NA-A-N-----------SG-WQRNMT-VNYFE----QL---------IDH--S-NA----------------A--LGTFQQ--------------------------RWW-GDL-SAFT-NQS-----------------------------------------------------E-YAMLYINGEGE--AHGSPD---------------------G------------YPA-V-YGR-----NISAAMFGLEH-----------------RYYGES--M------------------------------PAP-------------LTN------------R------S-MLNY---LTVENA---------------LADLEAFRLYLQA--TVL---------------------------------------------KK-E--VKWFICG----------GSYSGALSAWS-----------KATYP--------AS--YL-----------------AAWSS-SGVVNA---RF-------------------D-YY------AFDGHIVSV-----------LPAVCEKAIRSVFDQ-FSAAYD-D---------------P---TQ----R---AAMMAI------------------------------------------FGTPA---YF-----T----KE---------DMAWMLADG-----------SAMA------------VQYGSK--N------------------YL-----------------------------------CDSIVP--LSK-------------------------------------------------------TN---------P-F--------EQYATIIKAL----WG-E---------SF-T-------SSCY-YSTE------------CLS-----------------------N-------AQYSDQ----W-AAAGYAWVYQC-CSQL-A---------------------YW---QSG--YPN-------------------SLRLD--VIT----T-D---YYI-N-QCRSAFGQN------TF-------------PDT---YT-FNAKF--GGAT-----------------P--NA---TN-VIALQ---------------GSDDP------WQTAGVQAPLGP--N------------------------YPEV-LAQCN----------G-------------CGHCGDLMSPL--P-T-----------------DPAS-LT-AQRE----AIVNY-LDLWLGRQQQQQVQLPK-----------------SKRN-KFF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9euka-a8y7q7 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMRIALW--------------------------------------AIAYLA---------------------------------------------------------------WQGH-AYVQTE-HVFPD----QL---------VDH--T-AI----------------GGGGARFSQ--------------------------RYF-RID-QFWSGPDG-------------------------------------------------------PVILQLCGEYT--CAGVTD-------------------GR------------QFPS-A-LAE-----RYGALVLVLEH-----------------RYFGKS--S------------------------------PFS-------------VLS------------P------RNL-TY---LTTFQA---------------LSDIACFTDWYQR--VHI-------------------------------------------GRAN-A--NKWITIG----------GSYPGALAAWY-----------RLKYP--------HL--TA-----------------GALAS-SAVVAP---FA-------------------E-FP------EFDEQVALS-----------AGPECTHALQDITAM-VEGALQEG---------------G---RL----A---DEMNAL------------------------------------------FSCS----QL-----S----DA---------DFLYLIADA-----------MAEA------------IQYGPS--V------------------SL-----------------------------------CDPIVQ--AESR------------------------------------------------------DD---------R-L--------AAFVEFVQGT----FYAS---------MS-N-------SPGD-YDGD------------TMA-----------------------S-------HRWVPD-------SSGRQWWWMK-CNEV-G---------------------WF---QIA--PG--T----------------NSIRSK--RVN----M-E---WHR-D-RCEKLFGDV-L--A-FP-------------PPC---HR-ASIEY--SGFD-----------------M--SV---SN-VVFTN---------------GVEDP------WQWAGASAFSSS-AH----------------------LRDSSVLLINCS----------Q-------------CGHCVDLHTPS--P-D-----------------DAPA-LT-TARS----TIIAH-IDRWLIGSALQVDLGSS-----------------AVPK-AIL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9hyme-b7s8r4 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDHKVYNFA------------LLSFILIIQ----F----IKLNS-----------------------LQVITA-TIET--------------------------------------TNSSS-SPYKYV-TKKFI----VP---------VDH--F-SFSL---------------N--NTFEM--------------------------RYF-VND-TWKS------------------------------------------------------GKNA-PIFFYTGNEGV------L--------------------ETFAANT-------GFMW-D-IAP-----TFGALIVFAEH-----------------RYYGES--M------------------------------PFGN-K----------SFD-----------------NVKNL-GY---LTSQQA---------------LADYVDLIVHLKS---DPS--------------------------------------------LK-H--SPVIAFG----------GSYGGMLSAWF-----------RMKYP--------HI--IN-----------------GAIAA-SAPVLQ---FTG------------Y---T-D-CQ------AFSRIVTSDFRAV--------HPNCEKVIRKSWES-IKNLTST----------------D---DG-------KKWISTK------------------------------------------FKVCGSL--T--------------TEENFK-TFKDFLLSV-----------YSNL------------AMVNYPYATDFL---------SPLPA-FPIR-------------------------------EFCKFVND--T---N---------------------------------------------LS----SDKD---------V-MTNL-----QKGINLYSNY-----TG-------------------R-LKCLDLSDPEPD-----------------------------------------------------L-GAA-NGWNYQA-CTEM-V---------------------MP---MCN--DG----------VN-------DMFEP-E-PWN---FT-----KYS-Q-DCFTHFNV-----------------------TP-KPEL-VCDMY--GCDD-----------------L--STA--SN-IVFSN---------------GLLDP------WSSGGVLR-N---------------------------LSS-SAVAIIIP----------E-------------GAHHLDLRGSH--P-S-----------------DPYS-VV-KARE----YHAYS-IKKWIREHREDLNNDPALGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9maxi-c1bml9 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MREAASLTA----------VSLLALLP-VL----S----ILLGG-----------------------VNV-------------------------------------------VHGVEELQ-GYYTYK-TEWYE----NL---------VDH--F-GFAI---------------N--STFKQ--------------------------RYL-IND-THWDS-----------------------------------------------------QHGG-PIFLYAGNEGD------I--------------------EAFAQNT-------GFMW-D-IAP-----EFNALIIFIEH-----------------RYYGKS--L------------------------------PFGK-D----------SLK---------------P-DPKMN-GY---LTSEQA---------------LADYARFVTEFKS--TRKG--------------------------------------------AK-D--SPVIVFG----------GSYGGMLAAWM-----------RIKYP--------HI--VN-----------------GAIAG-SAPVAQ---FD-----------------T-P-CL------NFGRIVTSDYSFY--------SKSCSGVISKSWAA-IDQVGKN----------------D---KG-------LQRLQSL------------------------------------------LKLCSKP--K-----------------SVE-PLKSFLTDV-----------WTSV------------AMMNYPYPTEFL---------MPLPG-NPVK-------------------------------YICGKMSP--T---T---------------------------------------------VPT---DPVA---------I-LKYV-----YEGLNVYANY-----SG-------------------K-AKCIDMDNAD-------------------------------------------------------Q-IGA-DMWDYQS-CTEM-V---------------------MP---FCY--NN----------VD-------DMFEK-S-DWN---FT-----TYA-Q-GCQERWKV-----------------------TP-RPKM-ADIMY--GSKK-----------------L--KAA--SN-IIFSN---------------GLLDP------WSSGGIMK-S---------------------------ISD-SVVSIIIP----------E-------------GAHHLDLRGSN--P-N-----------------DPVS-VI-HARK----LERSF-IRKWIRGARHEASRVYTTLWL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9maxi-c1c207 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLG--LK------------LI--AWVTFLDLA-L--ANNGE--KSFFLKLL------------DMKKL-------------------------------------------SSPTALS-DRSGIF-ISYYN----QT---------LDH--F-NE----------------ENK-KTWNQ--------------------------RYF-VNT-EFFNGTET-----------------------------------------------------A-PVFLLIGGEGT------AS-------------------DSWMKY---G-----AWY-G-YAK-----EVGALMIQLEH-----------------RFYGSS--R------------------------------PTE-------------NMS------------T------ENL-KF---LTSQQA---------------LEDIVEFIRFAKQ--QYS-------------------------------------------LN-E-T--NKWVTFG----------GSYPGSLSLWM-----------RSLYP--------EL--IS-----------------GALSS-SAPVEV---KV-------------------D-FE------EYLGVVENDMNI--------RDPKCVPEVKKAIQQ-IQALIVSA---------------P---DG----W---KKVAKI------------------------------------------FSLCDGW--------SG---D---NIQDLR-SFYASVLGA-----------FYSS------------AQYDSV--LN---------------N-DDLA-------------------------------HMCPYMSN--EYFG-------------------------------------------------------D---------SSLERL-----ASTLKG----------------------KYG-------GSCLNVNYKD-----------LLD-----------------------F-MTT---EEWA----HG-EDVGYRQWVYQT-CNEF-G---------------------WY---QTG--N----------------------IWGS--FFP----V-E---FYT-Q-QCRDVYGMDFTDEI----------------IAS-NANY-TNIMY--GSKNP-------------------PL---SN-TIITH---------------GSFDP------WHPMGILED-----------------------------MSESVKTFIIN----------G-------------TSHCYDLYPPN--PLS-----------------DSEE-LT-RARN----ITFEH-IKRWIK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9maxi-d3pjf3 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRS--IT------------AL--LFVCLMSIA-Y--AQNGR--DSFLIKLM------------DMKKV-------------------------------------------LSPPELK-DTSRIS-TSFYD----QT---------LDH--F-NT----------------KNK-KAWKQ--------------------------RYF-VNE-ENFKDKEN-----------------------------------------------------G-PVFLKIGGEGT------AS-------------------IGSMKY---G-----SWY-E-YAQ-----KVGALMIQLEH-----------------RFYGES--R------------------------------PTE-------------NLS------------T------ENL-KY---LTSQQA---------------IEDIVEFIAHIKE--KYD-------------------------------------------IP---N--NKWITLG----------GSYPGSLSLWM-----------RSLYP--------EL--IA-----------------GALSS-SAPVEA---KV-------------------D-FE------EYLGIVNNDMRI--------RDPDCPAAVIEGIKE-TEALINSG---------------K---EG----W---QKVAKI------------------------------------------YKLCPGW--------SG---D---NEKDVK-TLFGSIVET-----------FAGA------------SQYDST--LS---------------T-NDVS-------------------------------QLCSHMKN--SNFG-------------------------------------------------------D---------TNMEKL-----AGTLIA----------------------VNG-------GSCINVKYED-----------FID-----------------------F-MRN---EEWS----VD--DDGYRQWIFQT-CNEF-G---------------------WY---QTG--N----------------------LWGS--FLP----V-E---FFV-E-QCTDVYGAEFTSEK----------------VYS-SAKY-SNDFY--GAKNP-------------------SL---SN-TIITH---------------GSFDP------WHPMGILND-----------------------------MNDSVKAFVIN----------G-------------TSHCFDLQPAN--PLF-----------------DSDQ-LT-HVRK----TTFEY-IKKWIK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9neop-c9w8j6 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-NARNVF-VTWIR----MP---------LDH--F-DP----------------QNP-TEFLM--------------------------RFM-FNE-QFFGG-DG-----------------------------------------------------S-PIFIMVGGEWD------ID-------------------HRWLLA---G-----NMF-E-MAR-----ENKGYQVYTEH-----------------RYYGGT--K------------------------------IFA-------------NFT------------A------ENL-RF---LNIDQA---------------LADLAYFITEMK---KQP-------------------------------------------RF-A-E--SEVVLYG----------GSYAANMVMWF-----------KKRYP--------HL--VV-----------------GTVAS-SGPILA---KV-------------------D-FP------EYLEVVHEAFML-------EGGEECIGHIRRGVEE-TIAAMQ-T---------------E---SG----R---RLLEQS------------------------------------------YRLCAPL--------DY---D---NEN-EL-GVFAGLISW--T--------FSTS------------VQQARP---------------------GTLQ-------------------------------AVCQSFTDHTSYGS-------------------------------------------------------T---------P-ME--------KFGGYIA----------------------IIRRLSD-TSCWSINYDS-----------FLT-----------------------S-YNE---------------TTNSRAWYYQT-CTEY-G---------------------FY---QTAP-RSGTA-----------F------DGLK--WLS----L-D---FYV-D-ICKRIFDERFDLAF----------------VED-GAER-VNLIF--GGLEP----------------V------VNN-TINIH---------------GYIDP------WRALGVYKNDI----------------------------SETSPTYTVN----------R-------------ASHCFDMQGWL--Q-S-----------------DTIE-MT-AVQQ----RARRT-VASWLSKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9stra-f0wif4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNESESTLLLSPPR----FTDYVKVPSKEVTGFSAPNRLHIGKASVLIGQIVMSFR-PIQL-------------ILLVAILV-------GVFIFAL------LGYK------------DYQRSID--------------------------PL-RI-I-------ATSTYFNK-TKLNWS-EEWIT----QR---------VDQ--F-SWPSS---------YSRSQP-PLFYKQ--------------------------RYL-INN-ETWDPND-------------------------------------------------PK---A-PTFFYTGNEAS------DV-------------------SLYANH-------TGLMW-E-YAA-----HFKALIVFAEH-----------------RFYGLS--Q------------------------------PFNS-SQL-------IPSH------------L----------RY---RTHEQA---------------IADYALLLESIQK--R---------------------------------------------FHGD-R--HPVITFG----------GSYGGMLSAWF-----------RIMT------------------------------------------------------------------------------------------------AGSAPNCAEKIRQAWPA-LFSM---AENE----------------PG----R---LQLAKI------------------------------------------FHLCRPL--------QN--------ETGIH-HLALWLLNA-----------FSVL------------AMRNYPYPSSYLSN-----GEAQLPA-WPMQ-------------------------------SACSFLADQRP-------------------------------------------------------DSIA---------L-ISSL-----FEAVSVLYNA-----TKK----------MD----------CVDLPRD---------------------------------------------------------MTSIDGIWGFHY-CTEM-L---------------------LQ---ETYFSSNGIS----------------DMFWNR--TI----SA-K---FVQ-Q-HCQRVWGTKPDPE---------------------WI----RIMY---GDAD----------------T--LLSAASN-IVFTN---------------GMLDP------WRCCGVKKSQVRNN---------------------------RIKVLKIE----------N-------------AAHHLDLFFHH--V-D-----------------DPNP-LL-THDT----FK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
9stra-f0wq48 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-ELSFK----QR---------LDH--F-NVAQ-----------------NASFPQ--------------------------RYF-FCD-PYELNAA-----------------------------------------------------ID-AVFFYLGNEAE------V--------------------TLYLNHT-------GWMW-E-NAW-----EFKAALIFAEH-----------------RYFGRS--I------------------------------PFPK-E----------SI-------------------RQNM-GF---LSSEQA---------------LADYAALITSIKQ--NR--------------------------------------------THLQ-R--APFIGFG----------GSYGGMLAAWF-----------RVKYP--------HI--ID-----------------GVIAA-SAPVLA---FMG------------DQ-RPVD-ME------GFARVSTFDATMGA--G---ASSNCASNIRQSWQS-MWKLSKT----------------L---QG-------REKLSKI------------------------------------------FQLCNDAILH--------------SEKDAE-AMIMWAKEA-----------FDYM------------SMGNYPYPTSYIMN----GE-STLPS-YPVR-------------------------------VACGFLSD--AFV-----------------------------------------------VPK---EEDT---------L-LEAF-----VRSIGVYYNS-----TK-------------------Q-KSCHDMKPA----------------------------------------------------S-EKS-RRDADFWDYIY-CSEL-Y---------------------MP---STT--DG----------IH-------DMFWPV--AWN---QS-----EDN-A-NCIKTWGV-----------------------SL-RPFW-AVTQF--GGLK----------------AL--QRA--SN-IVFSN---------------GNYDP------WSATGVTKSI---------------------------SS--SVVYIPVP----------G-------------GAHHIDLFFSN--D-L-----------------DPPE-VR-KARQ----LERQN-IRRWIRRVSVSTLE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
acypi-c4wwu8 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-IDSHIK-T---------------I---KG----A---KLIENK------------------------------------------FKLCDPL--------DI---N---TKNDVA-NLFETLAGN-----------FADI------------VQYNKD--NRFYEN---FE----RSL-VTLE-------------------------------TLCDVMVN--KSKT-------------------------------------------------------T---------P-LDRY-----ADVNSKLLS-------------------INN-------LTCTQHVYTK-----------MID-----------------------S-YLN---TSWN----SDSA-AGGRQWTYQT-CTEF-G---------------------FY---QTS--SQE------------------DHAFGD--KFP----A-K---FFI-D-MCSDIFGKLYNLDL----------------LSN-AIKR-SNMMY--GELNI-------------------KE---NR-VIYVH---------------GSVDP------WHALGITHT-----------------------------KTKNNVAIYIE----------G-------------TAHCANMYPPS--P-T-----------------DLPQ-LK-NARE----TIRAF-LSEWLTENDIDDFFEVNNIQFKY----KV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ =====>
aedae-q0iea6 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MI------------------VKAFAF------------------------------LGIA-VA-LASAA--ITINPSRPV--------LFGTH-----RVIPR-----NLG------------------------------SNAES--NNTAL-WNTVN----LR---------QVY--T-NP----------------QNR-NSFSM--------------------------RYV-TNN-RHYRR--G-----------------------------------------------------G-PIFLFVGGPWP------LE-------------------AHLVEQ---G-----HFV-D-MAA-----EMNGFLVANEL-----------------RYYGES--I------------------------------PVE-------------DVS------------R------NNF-RY---LHNVQI---------------LSELATFIAHLKE--DVV-------------------------------------------RD-P-N--AKVILAG----------VGYSASLAQWM-----------RQRFP--------HL--IH-----------------GVWSS-SGMVRA---ST-------------------N-YR------EFAEVVGENIRR-------FGGDDCYSTIWRAFRT-AENLID-----------------A---GL----S---TTVDEL------------------------------------------FHTCRPI--------DA---A---NALEVE-AFFYGIFNE-----------ISRE------------VVDADL--R------------------GNIK-------------------------------QMCEPLTA--SDDE-------------------------------------------------------N---------S-LLEL-----ASWLTGRFP--------------------N--------AECLAMDFQS-----------IVD-----------------------T-YNT---IDVDS----EIVKSGERQWMFQR-CTEL-G---------------------WP---LTA--ASQ------------------YQPFGR--RFS----T-D---LFH-G-ICEQLFDDWLTRDR----------------FEA-LIRQ-TNDYY--GGARP-------------------DI---RN-SISTQ---------------GTLDP------WSFAGVREVI-----------------------------FNNTYVTIIR----------D-------------AFHGQDMASIS--E-E-----------------DSIE-LR-RSKE----MVRDT-IRRWVETR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q16lf2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MW------------------IPTTVA------------------------------LSMV-VA-FAAAA--IESNPARPV--------LFGSQ-----KTAPP-----RGPP---------------------------SDSIVDN--GNYTE-WRVFD----QR---------QSH--S-NA----------------HSV-DMFPM--------------------------RYV-SNS-KFYRP--G-----------------------------------------------------G-PIFLFVGGPWE------LE-------------------QHFVEQ---G-----HFV-D-LAE-----ENNAFVVANEM-----------------RYYGES--L------------------------------PVP-------------NAS------------R------GNL-RL---LHIVQA---------------CTDIARLIVHIRY--EVL-------------------------------------------RD-P-N--ARVIVAG----------VGFSGSLAHWT-----------RLRYP--------HL--IH-----------------GVWAS-GAMLQA---NE-------------------N-YR------EFAEEVGEYIRR-------YGGNDCYGALWRGFRT-AENLID-----------------A---GQ----S---QTVDKL------------------------------------------FKVCTPI--------NG---T---NPLDVE-AFFYGIFNE-----------VVSN------------TLRPNL--R------------------QNIR-------------------------------NMCDTLTH--EDHD-------------------------------------------------------S---------S-LTGL-----ASWITGQFP--------------------E--------AECLAMDLES-----------IVQ-----------------------L-FQE---TDWQH----DVHKSGERQWFYQR-CTEL-G---------------------WP---LTA--DSM------------------NQPFGV--RIS----S-N---LFQ-Q-LCQRVFDGWLTSDV----------------FRS-LVRQ-TNTLY--GGNRP-------------------EM---RF-VFYTH---------------GSLDP------WRFTGVTTVL-----------------------------YNNNYVNVIR----------G-------------AIHGEDLASIS--D-L-----------------DWAD-LR-RSKE----EVGET-IRRWLERRV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q16mc1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIF---L--------VVALLLVS--P-------------------------ALLEASPQTYWEQLHR------------EPP-------------------L----RGHPRNVT----RQAE-VKWIM----QY---------VDN--F-DPQ----------------N-PSTWSM--------------------------RYI-QNG-EHY-------------------------------------------------------QPGG-PLFIFLGGEWE--ISPGY-------------------------------VMYGHFY-D-MAK-----ELGAHLFYTEH-----------------RYYGQS--R------------------------------PTAS-------------TR------------S------DLL-KF---LNIDQA---------------LADLAHFVEEMRR--AIP--------------------------------------------GAE-N--SKVIMAG----------GSYSATMVAWF-----------RQKYP--------HL--VD-----------------GGWAS-SAPLLA---KL-------------------D-FV------EYKEVVSESIRLV-------GGDACADRIERAYEQ-IEDHLARE-------------------EF--------DKVREE------------------------------------------FKVCNNINFA--------------NSLDSA-MFLSSISDY-----------FAGV------------VQYHSP--G-------------------DIE-------------------------------GVCEIIMD--DSIEN------------------------------------------------------D-----------MEAL-----ANWF--IRGV----------------------------NQCMDMTYDSTIRY-----------------------------------YRS---IDWN----HGANRGAMRPWLYQT-CAEY-G---------------------WY---QTS--GSE------------------NQIFGS--GFP----V-D---LYV-R-MCYDLYDYIFYPAR----------------LDA-NIKR-TNTIY--GHMNP----------------------EVTN-VFFTQ---------------GQLDP------WRPMGLQEDLN-----------------------------DQSPTVVIP----------M-------------ASHVADMGSIS--D-R-----------------DSPE-ML-AAKE----RVFEL-IKQWIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q16x18 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKLAWILTLYLALSPV------D-A-GRSFWRGKK---------FT--QDEPSK------------NP---SFK-----GLG-----------------------SNVQ-TLWFD----QL---------LDH--N-DPT----------------N-PTTWKQ--------------------------RYN-VND-EYFKNEE----------------------------------------------------DNG-PVFLMIGGEGE------AT-------------------ARWMTE--------GAWI-R-YAQ-----EYGALCFQLEH-----------------RFYGKS--H------------------------------PTE-------------DLS------------T------KNL-AY---LTSEQA---------------LADLAYFIEAMKQ--KYQL-------------------------------------------G-R-S--NRWIAFG----------GSYPGSLAAWL-----------REKYP--------YL--VY-----------------GSISS-SGPLLA---KI-------------------D-FK------EYFEVVADSLNRY--------SPECVANVRSAMSQ-VETLLKHM-------------------IG----Q---RNLNDK------------------------------------------FKLCDPVEKS------------IANELDLS-SLFEAIASN-----------FAGV------------V--------H------------PHAR-LTID-------------------------------EVCDVMMN--QTI-GA---------------------------------------------------------------P-VSRL-----AVVNEMVMKQ-------------------------DK-AKCLDYVYDK-----------TIK-----------------------Q-MQN---TSWDSD-----VASGARQWIYQT-CNEF-G---------------------FY---QTS--DN------------------AESVFGD--RFP----A-E---FFT-R-QCADVYGRRFDQKA----------------LSR-AVYR-TNTNY--GALNP-------------------S---TTN-VLYVH---------------GSIDP------WHRLGLTESNDI-----------------------------QMPTIFID----------G-------------TAHCANMYEPK--E-D-----------------DFPQ-LK-AARV----QISSF-IGRLLKMDDDYDY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q16y04 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHK-------------------LVLVAVL-AL-AA-VT-VAE-K--KPI-SVASL--------V----DKIL-NANPM-----PNIP---------------------------VGYKSEN---SRTT-GHLFR----TR---------VDH--F-NP----------------QKR-DTFQF--------------------------EYF-SND-QYYRP--G-----------------------------------------------------G-PIFIVVGGNFP------VS-------------------PYFLEH---G-----HFH-D-IAF-----YENAWMFTNEH-----------------RFYGNS--M------------------------------PTE-------------DLS------------V------ENL-RY---LTVEQT---------------MVDLAEWIFHLRQ--NVV-------------------------------------------RD-Q-N--ARVILLG----------TGYSGAIATWM-----------RQRYP--------HL--VE-----------------GAWVS-SGQIEA---RF-------------------N-FK------EYAEEVGELIRD-------YGSNECYSQIWRAFRT-AENLID-----------------A---GL----G---STVSEL------------------------------------------FNTCEPI--------VT-DDI---TMLDVE-TFFWHVKTA-----------LQRG------------VLDEQD--T------------------DTTN-------------------------------ELCERLNN--STEA-------------------------------------------------------T---------D-LQTI-----ANWVHEFYD--------------------F--------LDCMPFDFDA-----------AID-----------------------A-HQY---VDPKV---PENAVYGLRQRTYQL-CTEF-G---------------------WF---LTA--DSH------------------DQPFGY--RVS----M-Y---FFL-N-VCRSVYGDWLNSQV----------------VYD-GVHL-TNMHF--GGQNP-------------------RI---SN-VFFTN---------------GGLDP------VRDVSITEYY-----------------------------LAGSGATVIP----------G-------------YFGSEDLHSIS--G-Y-----------------NSPE-MI-EAKH----TVHAF-IESWLWEPIVPI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q16y05 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANR-------------------LALVALL-AL-AT-VA-LAE-R--KPI-KIAPI--------A----HKIL-EAYPI-----PQVP---------------------------EGYKSTN---PHTI-GHKFR----TR---------VDH--F-NP----------------QNR-DTFEF--------------------------EYY-SND-EFYRP--G-----------------------------------------------------G-PIFIFVGGNWP------LD-------------------QYYIEH---G-----HFH-D-IAN-----YENAWMFANEH-----------------RYYGHS--F------------------------------PVP-------------NLS------------V------ENL-QY---LTVEQA---------------MVDLAELIYHVRH--NVV-------------------------------------------RD-D-D--ARVILLG----------TGYAGAIATWM-----------RQRYP--------HL--VE-----------------GAWVS-SGQIEA---RF-------------------N-FK------EYAMEIGELIRD-------YGTNECYSQIWRAFRT-AENLMD-----------------A---GL----A---NTVTDL------------------------------------------FNTCERV--------DT---E---TMLDVE-TFFYNVKEA-----------LQRA------------ILSEQD--T------------------ETTE-------------------------------ELCENLNN--STEA-------------------------------------------------------T---------D-LHTI-----ANWIEDFYY--------------------Y--------LDCMPFDFDT-----------TVA-----------------------A-HQF---EEIGY---PENAILGLRQRVYQF-CTEF-G---------------------WF---LTA--DSP------------------DQPFGY--RVT----M-Y---FFL-N-FCRSVFGDWVTSEV----------------VAD-GVHL-TNMHF--GGKNP-------------------RI---SN-VLFTN---------------GALDP------VRDVGITEYK-----------------------------QPSSDAIVIP----------G-------------YFNSPDLNSIS--G-Y-----------------NSPE-LL-EAKH----LIHKY-VELWVWQRATPYKGQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q16y06 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MITRSVIL--------LAVL-------------------------------------------------LAVAN---GMVR-EAWFE----TK---------VDH--F-NP----------------RNV-DTFSM--------------------------RYY-SND-EHSYP--K-----------------------------------------------------G-PIFVIVGSNGP------IE-------------------TRYLSE---G-----LFY-D-VAY-----LEGAFLFANEH-----------------RYFGHS--L------------------------------PVD-------------DAS------------T------NNL-DF---LTIDQA---------------LADLAAFVHHIKH--EVV-------------------------------------------RN-P-E--AKVILMG----------YGYGGSLATWF-----------HQQFP--------HL--TN-----------------GVWVS-SGTVEA---DF-------------------D-LT------GYMESLGETIGE-------FGGRGCYGTIFSGFRV-AQNLIA-----------------M---DR----A---DVLNEQ------------------------------------------FNLCEAL--------DT---D---DVMDST-AFLLGLQRA-----------IEDE------------IMHLRN--T------------------QSTT-------------------------------DMCGIIDNEEDTIE-------------------------------------------------------N---------S-LLAL-----GNWFAEEHQ--------------------F--------ETCVDLSFEA-----------FMA-----------------------P-YMD---TDFDD----SDLQAGHRQRLYLQ-CTGT-G---------------------FF---ATS--DSF------------------YQPFGD--QID----S-D---FYV-E-VCRHAFGDWINEDL----------------IRA-QVFR-TNVRF--GGKQP-------------------EI---DN-AHFTH---------------GDIDP------MMVTGIVEDL-----------------------------NEEAEATVIP----------N-------------TFHAPDLESID-YV-Y-----------------DSPE-LI-AAKE----HTRNL-IDLWIFEDFDPIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q16y07 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRG-------------------IVLVTLA-LVVMT-AT-AASVS--RRV-PNKEL--------SRTLMQQVMTKRFSS-----TKPA---------------------------VDDP-A---KRIVI-ENFFT----TR---------VDH--F-NS----------------QNT-AEWTL--------------------------RYF-AVT-DYYMP--G-----------------------------------------------------G-PILIFLGGNQP------IL-------------------TSMVDES--T-----LIY-D-MAR-----EMNGAVYAFES-----------------RFYGQS--F------------------------------VTE-------------DAS------------T------ENL-SL---LNTDQI---------------LADLAEFVQYLKR--DVL-------------------------------------------KN-P-N--APVMVSG----------SEYGGALATWF-----------RVRYP--------HL--AQ-----------------AAWSS-SGYHHA---LM-------------------D-FQ------EFSEAWGQTLID-------HGSQECYNDIFVAFHV-MQNLID-----------------I---GL----G---DILYDK------------------------------------------FNICSPI--------DP---E---NRIQVM-YFFSVLMTA-----------VEIY------------TLRNHD--L------------------NDFA-------------------------------DVCQDITD--DDFP-------------------------------------------------------T---------A-LDAF-----ANWFNTKFA--------------------ED-------IGCVVTDVDT-----------MVE-----------------------A-FSQ---PAWDD----AFTMMGARQAMYQM-CNEF-G---------------------WF---FTT--DSD------------------FQPFGS--RVY----L-E---LYS-E-TCRMVFGDWISYES----------------IYY-ATQR-ANNRF--GGNDP-------------------RI---TE-VHFTN---------------GAEDP------WRMISITSDR-----------------------------NALALADVIP----------R-------------ELSSSDLPAI--SE-N-----------------DSEE-LQ-EVKR----RVKAL-MSTYLYPV-SPRKMAKSEEVVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
aedae-q179r9 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTKETH--------------S--LILGLL----V----I-------------------------------------------------------------------------CLMTAQIS-AKYEYQ-IKYLD----VP---------LDH--F-TYVN---------------E-SVTFKM--------------------------RYL-VND-TYNPDGK------------------------------------------------------G-PILFYTGNEGD------I--------------------ENFAQNT-------GFMW-D-IAP-----KLKASLVFAEH-----------------RFYGKT--L------------------------------PFGN-A----------SYE-----------------SPKHL-GY---LSSEQA---------------LADFADLLAEINP--SNRS--------------------------------------------TR-G--RPVIAFG----------GSYGGMLAAWF-----------RMKYP--------HL--VT-----------------GAIAS-SAPIRQ---FD-----------------T-D-CG------VFSQILTSVFSVA-------YTRECSLNIARSWDT-LKNYSST----------------A---DG-------LKTLKDK------------------------------------------FKFCGNI--T--------------KAEDITETFFDYLTDV-----------YGNL------------AMINYPYNSSFL---------APVPA-YPVR-------------------------------EFCGRLAQ--N-------------------------------------------------FT-----GLE---------L-IGRL-----QEALSIYSNY-----TG-------------------K-TKCLNIANAYDD-----------------------------------------------------N-MGT-SGWDFQS-CTEM-W---------------------MP---MCS--EGS---------GK-------DMFPK-K-AWD---EK-----KFS-D-DCFKKFGV-----------------------RP-KKTV-ALTTY--GGLY----------------LD--G-A--SN-IVFSN---------------GLMDP------WSGGGVLQ-S---------------------------PNN-AIKVVLIP----------E-------------GAHHIDLRAAD--E-N-----------------DPGS-VR-GARQ----VHLQN-IQMWIKQYRKMMG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
ailme-d2hs98 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDH--F-GFTA---------------D--ETFKQ--------------------------RYL-IAD-EHWK------------------------------------------------------KNGG-SILFYTGNEGD------I--------------------TWFCNNT-------GFMW-D-VAD-----QLKAMLVFAEH-----------------RYYGES--L------------------------------PFGN-K----------SFK-----------------DSRHL-NF---LTSEQA---------------LADFAVLIKHLKR--TIPG--------------------------------------------AK-N--QPVIAVG----------GSYGGMLAAWF-----------RMKYP--------HM--VV-----------------GALAA-SAPIWH---FGN------------L---V-P-CG------VFMEIVTKDFKRS--------GPNCSETIRSSWDA-INRFART----------------G---AG-------LRWLSEA------------------------------------------LGLCTAL--T--------------NTEDVQ-RLKAWISET-----------WINL------------AMVDYPYESDFL---------QPLPA-WPIK-------------------------------VVCQYLK---N---P---------------------------------------------SV----SDAQ---------L-LQNI-----FQALNVYYNY-----SG-------------------Q-ASCLNISETTTS-----------------------------------------------------S-LGT-QGWSYQA-CTEM-V---------------------MP---FCT--NG----------ID-------DMFEP-H-LWN---LG-----EFS-D-DCFKQWGV-----------------------RP-RPAW-IITMY--GGKN-----------------I--SSH--TN-IIFSN---------------GELDP------WSGGGVTK-D---------------------------ITD-TLVAITIP----------E-------------GAHHLDLRARN--A-F-----------------DPTT-VL-LARS----LEVRH-MKQWIRDFYASLRKKH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
ailme-d2hwj8 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALWLG------------PLLLLSLG--GPS-AP-ASLLR--RLGE----------------HIQQFQE--SQ-----------------------------GLS-----LTLGPGA-GALPK--QGWLE----QP---------LDP--F-NT-----------------SDQRSFLQ--------------------------RYW-VND-QHWAS-QR-----------------------------------------------------G-PVFLHLGGEGS------LR-------------------SGSVMR---G-----HPA-A-LAP-----AWGALVIGLEH-----------------RFYGLS--I------------------------------PAE-------------GLD------------V------AQL-RF---LSSRHAECAGTPSEEGPQSLPSADVASARRALAR--LFN-------------------------------------------VS-T-A--SPWICFG----------GSYAGSLAAWA-----------RLKFP--------HL--IL-----------------ASVAS-SAPVRA---VL-------------------D-FS------EYNEVRTAGGGC-------GGGRGCGEPP----DS-FSRGPTVG---------------G---VQ----K---PNEHGC------------------------------------------WPACSS----------L---G---GAEDQA-ELLGALQAL-----------VGGA------------VQYDAQ--AG--------------VP-LSVR-------------------------------RLCGLLLG--PSGS-R----------------------------------------------------SA---------S-YHGL-----RRAVQVVMR-------------------SLG-------QRCLSFSRAE-----------TVA-----------------------Q-LRV---TDP-----HVS-GVGDRQWLYQT-CTEF-G---------------------FY---VTC--EDP------------------RCPFSQ--LPA----L-P---SQL-E-LCEQVFGLS--TAS----------------IAR-AVSQ-TNSYY--GGQTP-------------------GS---TH-VLFVN---------------GDTDP------WHVLSVTQALG---------------------------P--SESALLIP----------G-------------ASHCMDMAPER--P-S-----------------DSPS-LR-LGRQ----SILQQ-LQTWLGPAKESQV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
ajecg-c0nst6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA----------------------------IQSVAVFR----------L-ALLFAFMQLAVAS-IR------VDWQ---------------------------------------------------DPLS--------IPRPETDDAD-LKARYP-VHKFK----TL---------IDH--F-PS---------DPRYEPHTG--EKFDL--------------------------RYW-FDA-SHYKK-------------------------------------------------------GG-PVIVLHGGEAN--GEGRL---------------------PFLQK--------GIVK-I-LSE-----ATHGLGVILEH-----------------RYYGQS--F------------------------------PT--A-----------NLS------------T------ESL-RF---LTTEQA---------------LADSADFAQNVVF--EGF---------------------------------------EDVDLTAK-GGNAPWIAYG----------GSYAGAQVAFL-----------RAQYP--------DI--FW-----------------GAISS-SGVTKA---IY-------------------D-YW------EYFEPVRKY-----------GPPECVSTTQKFVDM-VDTIIIGLSD-----------------------PKKTKRLKSF------------------------------------------FGLE-GL-------------------THND-DFANVLAWGISY--------WQSV------------NWDPK------------------IST-RKFD-------------------------------YYCGNITA--DE-LLY----------------------------GNGD--LK--DEAEELLIAGGYGK--------EVGTLANRL-----LNFAGFLHHDQL------VYCKET-----E---Q--TMDECLGQHDMAW--------------------------------------FK------N-----DSLAQADNRCWPYQV-CTEW-G---------------------FL---QVG--STV--------------PQDQMPMVSR--LID----L-E---YAS-I-MCREAFGI---------------------YRPS-DVNR--VNKY--GGFDI-------------------E---YER-LAFID---------------GEVDP------WRPATPHS----E---MA--RPR--------------KSTLEKPFILIE----------G------------A-GHHWDENGMLAN--E--S----------TPMLPPKA-VA-DAQA----QEVKF-VKKWMKDWEQELRQR----LTNKQTMISHGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
ajeds-c5jlb4 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MA----------------------------IRSMVALR----------L-VLVFALIQSVVAS-VR------LPNNPM------------------------------------------------LIGLS--------TPSTESDKDD-LTARYP-VHKIK----IP---------IDH--F-RS---------DPRYEPHTE--EKFDV--------------------------RYW-FDA-SHYKK-------------------------------------------------------GG-PIIVLHGGETN--GEGRL---------------------PFLQK--------GIVK-I-LSE-----ATNGLGVILEH-----------------RYYGES--F------------------------------PT--A-----------NLS------------T------ESL-RF---LTTEQA---------------LADSAYFAQNVVF--EGF---------------------------------------EDVDLTAK-GGNAPWIIYG----------GSYAGAQVAFL-----------RVEYP--------DI--FW-----------------GAISS-SGVPKA---IY-------------------D-FW------EYFEPVRKY-----------GPPECISTTQKFVDM-VDKIIIGLND-----------------------SEKTKRLKSL------------------------------------------FGLG-EL-------------------THHD-DFVYSLAWGISY--------WQSV------------NWDPA------------------IST-RKFD-------------------------------YYCGNLTA--DE-LLY----------------------------DNGD--KK--EEAKELLTAGGYGK--------EADALANRL-----LNFAGFVYVDQV------TGCERR-----E---Q--TLDECLGQHELPW--------------------------------------FK------N-----DSLALADYRCWPYQV-CTEW-G---------------------YL---QVG--STV--------------PKDQMPVISR--LVD----L-E---YAS-I-MCRKAFDI---------------------HKPS-DVDR--VNKY--GGLDI-------------------E---YDR-LAFVD---------------GEVDP------WRPAGPHA----E---GA--RPR--------------KNTINKPFILIE----------G------------A-GHHWDENGLFPN--E--T----------TPDLPPKP-VV-KAQA----EEVKF-VRRWVKGKFPLIIRSSGDRFSSKETFGTLRP---------LPYIP---------------G----LN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
anoda-e3wny2 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MW------------------VSKVFC-A-------------------VYLVTLI-VCGAS-GR-SASAA--IDS-KNVRL--------L----KDLQ-RHLAQ-----PVIP---------------------------DTYQGSE-GNPRLI-GARFR----TR---------VDH--F-DP----------------QNR-DTFEF--------------------------NYY-SND-EFYQP--G-----------------------------------------------------G-PIYIFVGGNFQ------LT-------------------TYYIEH---G-----LLY-D-TAA-----RDHAWLFTNEH-----------------RYYGTS--T------------------------------PVE-------------NYS------------T------ENL-RF---LHTEQV---------------LTDLIEWIDHLRN--EVV-------------------------------------------RD-P-N--AKVILMG----------VGYAGALATWA-----------RQRFP--------NI--VD-----------------GAWGS-GATVLA---SF-------------------D-FQ------EHANDIGSIIRR-------FGGDECYSTLWVAFRT-AQNLID-----------------S---ER----D---ETVTTL------------------------------------------LNTCEPI--------DS---G---NLLDVE-TLFYHLKLA-----------IQEA------------VFQGYN--T------------------TRIE-------------------------------QLCSSLVN--KDEP-------------------------------------------------------T---------A-LSAL-----AAWLDVYYA--------------------N--------LPCNPFDFDA-----------NME-----------------------A-GKV---LQPGA---AENVILGLRQTQYQA-CTEF-G---------------------RF---GQP--TMI----------------------------------------------TSPLFGGWVTDAV----------------IYD-GVRL-TNIHY--GGQDP-------------------RS---TN-VLFTN---------------NEFDP------NRLLSITRYI-----------------------------NPLSYAYVVP----------N-------------EFISSEIYSIN--E-Q-----------------DSDE-LT-TIKQ----NIQQY-FTLWLSGGMTPL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
anoda-e3wny3 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-DF---LNADQA---------------MADLAEWITYLKQ--TFV-------------------------------------------RN-P-N--AKVILMG----------TGYGGALATWF-----------RQKYP--------HL--AD-----------------GVWVS-SGAIEA---NF-------------------A-FS------GYNEALGESIRE-------YGSDACYSTIWTGFRV-AQNMVS-----------------L---GF----S---DLLSEE------------------------------------------FHLCDPL--------DT---D---SELDAT-AFLLGLRDD-----------IEFE------------MLHRRN--T------------------NSIK-------------------------------EMCAELEEER---D-------------------------------------------------------S---------S-LNAL-----IDWFAREHQ--------------------Y--------EQCVHLNFDR-----------YME-----------------------R-FVE---TNFNT----ANLQAGHRQRLYLQ-CTEE-G---------------------FF---PTTA-HSE------------------DQPFGN--QIG----T-S---FFV-A-VCQRAFGEWLTEDV----------------ILR-QIRS-TNARF--GGLQP-------------------AI---ER-AHFTN---------------GGVDP------YRAGSLLQDL-----------------------------NPKAPATLIP----------H-------------TFVSPDLESID-YE-Y-----------------DTEE-LI-AAKE----RTRNL-IDTWIFEDFEPIIHEV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
anoda-e3wuw3 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN------------AAEQFLTHAADLVLECKVYRL------S-H-TKRETSWKR---------FH--PDAPSR------------TV---TRT-----KVDGA---------SEALAGQQL-HIEETP-DQWFE----QI---------LDH--N-DPT----------------N-EATWQQ--------------------------RYY-VND-QFFDSSN----------------------------------------------------PHS-PVFLMIGGEGE------AT-------------------ARWMHE--------GAWI-H-YAE-----THGALCFQLEH-----------------RFYGKS--H------------------------------PTT-------------DLS------------T------KNL-AY---LTSEQA---------------LADLAYFIEAMNE--KYQL-------------------------------------------QPQ-T--NLWIAFG----------GSYPGSLAAWL-----------REKYP--------SL--VH-----------------GSISS-SGPLLA---KI-------------------D-FI------EYYDTVVRSLASY--------SPGCVEAVRSAMKQ-AETLLKHM-------------------IG----Q---RTLNDK------------------------------------------FKLCDPIERS------------IDNPLDVA-SLFEGLASN-----------FAGV------------VQYNKD--NS------------PHAT-ITID-------------------------------EVCDVMMN--TTI-GA---------------------------------------------------------------P-VSRL-----AEVNRMLLEQ-------------------------GN-QSCLDYVYDK-----------SVR-----------------------Q-MQN---ISWDSE-----VASGARQWTFQT-CNEF-G---------------------FY---QTS--NN------------------ASAVFGD--RFP----A-E---FFV-R-QCADIYGARFGEAA----------------LAR-GIYR-TNVNY--GALNP-------------------A---TTN-VLYVH---------------GSIDP------WHRLGLTESNDL-----------------------------HTPVIFID----------G-------------TAHCANMYEPK--E-S-----------------DFPQ-LK-QARL----EIDTF-ITNLLAIKDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
anoda-e3ww17 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-K-------------------LSVVLLVAMVAVS-VA-MAKNV--PKR--KGTL--------PLELVSKMFGGYGPL-----PKVP---------------------------EGYK-PS---PYTT-EGRFT----SR---------INH--F-DP----------------QDR-STFEF--------------------------NYL-TND-QYYRE--G-----------------------------------------------------G-PLFVVVGGHHR------LD-------------------PYFLEN---S-----HFR-D-VAA-----LNGAFLANNEH-----------------RFFGTS--V------------------------------PTE-------------DLS------------S------ENL-RF---LRTEQA---------------LFDLIEWIDFLKR--EVM-------------------------------------------GD-P-N--ARVIVHG----------FSYGGALATWA-----------RQRFP--------NI--ID-----------------GAWGS-SATVRA---TV-------------------E-FS------EFTEDFGNTIRV-------KGSDECYSAIFRAFHT-IENLLD-----------------A---GL----T---ERVSST------------------------------------------FNTCDPI--------DA---D---NALQVE-LFLHLMTLS-----------LEIS------------MFEDFD--I------------------ENVQ-------------------------------NVCNQLTD--DSFD-------------------------------------------------------T---------S-MEAL-----AEYLKNRYA--------------------DV-------RDCFDLSFEN-----------FIS-----------------------I-LGD---ESLDA---PQNLDYGLRQLNYHI-CTEF-G---------------------YF---QSA--RSR------------------EQPFGS--KVT----Y-D---LFL-E-ECAAVFGEWLTSEV----------------LYD-GVRL-TNFHF--GATDP-------------------RT---TN-VLFTN---------------GGIDP------FRYVSITQYQ-----------------------------NLLSNARVTP----------A-------------AFYTEDIRSIS--G-Y-----------------DSEE-ML-ETKH----MVEQY-ITTWLGSQISPFAVRK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
anoda-e3ww18 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-RF---LSVEQS---------------LVDLIEWIDYLRR--EVV--------------------------------------------RDP-N--ARVVLHG----------LGYGGAVAIWA-----------RQRFP--------QL--ID-----------------GAWGS-VASVIA---RV-------------------N-FN------EYGEDMGNTIRRL-------GSDACFGILWRGFRT-AENLIDAG-------------------------R--YERISEL------------------------------------------FRTCEPL--------IADD------PLTIE-TFFYGLKSS-----------I---------------EEEMYG--QANP---------------QSVV-------------------------------RMCQELEA--DTAGT----------------------------------------------------------------D-L--------EVLANFYERR----YA-A------------F--------ECVPFDFES-----------NIA-----------------------SAMYE---AVGVTT----NAVLGIRQRLYQL-CTEF-G---------------------WF---LTS--ATG------------------DSPFGT--RIT----Y-R---YFI-D-TCRAVFGDWIDQQV----------------VYD-GVRL-TNLHF--GADD-----------------P--RV---TN-VLYVN---------------AELDP------TRLVSITDYVNV-----------------------------QSNAFVIP----------G-------------EVVALDWLAPS--P--A----------------DSED-MG-RIKR----EIELA-TL----GPAAATTPRCSLVPIRI----ST----EPHMK-NLEPRRRL----------TPCDAMSPLLAMA----------TQQ------VIKASPM--------------K-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
anoda-e3x761 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPF-S---AENIT-EEFFV----TL---------VDH--F-NL----------------QNR-DTWSN--------------------------RYL-SLM-DHFVP--T-----------------------------------------------------G-PILIFLAGSNP------VN-------------------PALIDET--T-----LIN-E-MAR-----ELGGALFAFET-----------------RFYGES--Q------------------------------PTA-------------DLS------------V------ENL-RL---LNTDQI---------------LADLAEFVIHLRR--NVI-------------------------------------------GN-P-F--AHVLVAG----------TGLGGGLATWF-----------RVRYP--------HL--TD-----------------AAWSS-SGYLNA---IY-------------------D-FQ------EFSSGWAETAVQ-------IGGQECYNSIFVAFHV-AQNLVE-----------------A---GF----E---RLMYDM------------------------------------------FNICEPI--------DA---E---DRFDVA-YFFSVLMTS-----------IEVY------------TLRNGD--V------------------LEFE-------------------------------RVCGYITK--DEFG-------------------------------------------------------T---------P-LEAL-----ADWFNKRFE--------------------ED-------NGCIIVDVHT-----------SVE-----------------------Q-FLT---ADPDD----EVNASGARQFLYQQ-CTEY-G---------------------WF---FTT--DSD------------------LQPFGE--RVQ----M-E---LYY-E-MCRLIFGEWITTES----------------MYR-GVVR-TNDLF--GGNSP-------------------VV---QQ-VHFTN---------------GALDP------WRYASVLSPL-----------------------------NSYALADVIP----------W-------------QLAGADLRATS-VE-N-----------------DSQE-LL-EVKA----RLKEL-LESYLFPA-NPRK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- =====>
anoda-e3xc97 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNMRSKEKQRKTIAHRTCSV-Q-----A---TFAIDASAKE--------------------KE----GKL---LAVAWLPKI---------HRLMLTDPVQAH---VQTVGLGVLAISSSPSTLVVST---VTTVV-MP-AGSVL--EAALPQQ-------------DVEQPPVARSVW-----NRL----------------HR-EPPI-----RGGAPTK-KAAPVT-TKYIM----QR---------LDH--F-DP----------------QNV-NTWSM--------------------------RYM-ENG-EHYQA--G-----------------------------------------------------G-PLFIYVGGEWE------IS-------------------EGSISR---G-----HVY-D-MAQ-----QLNGYLFYTEH-----------------RYYGKS--H------------------------------PTV------------------------------------------------------------------------------------------------------------------------------------------MTG----------GSYSATMVAWF-----------RQKYP--------HL--VN-----------------GAWAS-SAPVFA---KM-------------------E-FT------EYKEIVSESIRL-------VGGSNCANRIERGVQQ-VEELIA-----------------N---RQ----Y---AQVADK------------------------------------------FRLCSDV--------DL---S---KPLDMM-NFFSSISDE-----------FAGV------------VQYHSA---------------------GDIE-------------------------------GVCEVIES--VPNE-------------------------------------------------------------------MEAL-----AKFITSS----------------------LG-------GGCNSYGYKA-----------MVD-----------------------F-YKN---VAWN----HGA-----------------------------------------A---QSS--SKLT-----------------RN---------------------------------RFDDTR----------------IEN-NIAR-TNVMY--GG |
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