Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....640..5....650..5....660..5....670..5....680..5....690..5....700..5....710..5....720..5....730..5....740..5....750..5....760..5....770..5....780..5....790..5....800..5....810..5....820..5....830..5....840..5....850..5....860..5....870..5....880..5....890..5....900..5....910..5....920..5....930..5....940..5....950..5....960..5....970..5....980..5....990..5....1000.5....1010.5....1020.5....1030.5....1040.5....1050.5....1060.5....1070.5....1080.5....1090.5....1100.5....1110.5....1120.5....1130.5....1140.5....1150.5....1160.5....1170.5....1180.5....1190.5....1200.5....1210.5....1220.5....1230.5....1240.5....1250.5....
9acto-q3wjy8   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MADDDPHCWLEDV--AGEAALAWVREHNAETFAE-LTQSAEF-AG-LRAEIREVLDSD--DQIPYPVTR-GEYLYNFWRDAGHPRGLWRRTSLASYRDA---------SPDWEVVLDVDALAA----REGENWVWHGARVLRPE----YRLALVELSRGGADASVIREFDLVTK-------------------------------SF-V---EDGFFLPE--------AKSSVGWLDED-----RIYVGTDFGEG-------S--LTTSGYPRVIRE-----WRRGTPLDDAV-TVFEGEV-DD-----VS---VDAYHDPTEGFV-------RDF-VD-RSIDFYH-TETFLRIPT-----------------GLVR-IDV-PDD-AHTS-VHREWLLITTRSEWAVD----------------------EKVYPAGALLAADFEAF----LA------GRR---ELELLF--EPDKHTSLA-----YHA-WTR------NHLIVATLRDVKSQFTVLTPTA-------------SGW--------------------TRAPLADLPDTGSA---------------------------YIS-DTSPDVDDEYYLGASGYTQPATLYRGEIGV---------EPEIL--KQA--PAFFPTDGRTVSQYFAV-SDDGTRVPYFVVGTG------------------KPGPTLLYGYGGFEVS-LTPSY------------------------SGTVGRAWLA-------------------------RGGTYVVANIRGGGEYGPDWHQSAIRENRLRAYEDFAAVAGDLVGRGITTPAQLGIEGGSNGGLLMGVMLTRYP--ELFGAVVCSVPLLDMRRYHQLL-AGASWMAEYGDP-DD-PADWAFIKEYSPYQNVR--------PGRRYPPTFITTSTRDDRVHPGHARKMVARLREL----------GYA-IR-----YYENIEGGHSGAADNEQL---------AHKSALIYEFLWRTLGTGALSDGDR---PAAGAGRTE---------     =====>
9bact-q26h93   	----------------------------------------------------------------------------------------------------------------------------MALVSCED----------------KKQDSKKMTVTYPT-TQKVD--------HVDNYHG-----TDVQDPYRWLEDD--RSAETGEWVKSQNKVTNSY-LDQIRFR-ES-VKNRLTELWNYE---KIGAPFIEGD-YSYFYKNDGLQNQYVIYRFPTNGK---------M---EDAEVFLDPNQFSK----D--GT-----TSLGGTSFTKDGSLFAYAISEGGSDWRKIIVLNTNDL-------------------------------TQ-VGDTIKDV------------KFSGMSWKGND-----GFFYSSYDKPD-------GSELSAMTDQHKLYY-----HKLGTPQNEDQ-VIFGGTP-D----QKYRYVGGG--VTDDQNYL---------V-IS-ASTSTNG-GKMFMKELNKPN---A-------P----LVTVLD-NFD--------TNTYLL--------------------HNEGSKLWLVTDYNAPNKRIVSTDFSNPT---------------QENWTDVISETE---NVLS-----P-S-TGG------GYIFAEYMVDAVSKIQQYNYD-GT----------------------------------LVREVK-LPGIGNVGGF-----------------------------GAKEKDKTLYYSFTNYTTPGSTYLYDIATG-E--------SKLYRKPE---IQFNSDEYESKQIFYT-SKDGTKIPMIISHKKGL------------VLD-GKNPTILYGYGGFNVS-LNPSF------------------------SVS-RAAWME-------------------------MGGIYAVANLRGGGEYGKKWHDAGTKMQKQNVFDDFIAAGEWLKDNDYTSTKYLAIQGGSNGGLLVGATMTQRP--DLASVAFPAVGVLDMLRYNKFT-AGAGWAYDYGTA-EDNPEMFEYLKGYSPLHNIQE--------GVSYPATMVTTGDHDDRVVPAHSFKFAAELQSKQAG-------DAP-TL-----IRIETDAGHGAGKS-TAQV--------IQEQTDIYSFALFNMGFEELPELSTRVKM-----------------     =====>
9brad-q359i6   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSIDDRPTLA-----APDDDPYLWLEDI--EGERALAFVAAQNQRTLAA-FG-GAGF-ER-DRDMLAAIFDRS--DNIPFVSRR-GALLYNLWKDAAHPRGLWRRTTLAEFRKA---------EPQWEELLDLDRLAA----DEGEDWALNWVSTLPPA----HERAMLALSRGGSDAVVLREFDLAAK-------------------------------RF-V---ADGFTLTE--------AKGGVDWLDQD-----TLLLASAFGQG-------M--ATPSGYARTMRL-----WRRGEPIEAAK-VIFAAEN-SQ----SVW---VRAGIDRSVTPA-------RVW-FT-EGLDFFN-HHLWLGDAS-----------------GAGIKLDL-PTD-CWMT-ADGNFMAVKLRQPWTVG----------------------DVTHGADVVLGIRLSAF----LD------GVR---DFVRVF--EPGPRRALQ-----GLC-WAG------GRLVLSILDELKPQSEVWTPSA-------------QGW--------------------SCQRLPGLPELATVNVWPLDA-------------------------YELTGNGDLLASIQDPLTPPSLQLI-EGF--------GAPAVL--KQA--PRTFTAEGCVVTRHEAI-SVDGVGIPYTLTGPA--------------RPT-GDAPVYMSAYGGFGHS-IRPVY------------------------NAALGKLWLE-------------------------RGGTVVEANIRGGGEFGTAWHDAGRFAGKRLAHDDFAAVAADLVRRGVTVPKRIAAQGGSNGGILITNMLVRYP--ERFGALFCTIPLIDMRRYTKLL-AGASWIAEYGDP-DK-DEDWGWLQTYSAYHMAQ--------PGQPYPPILIATTRRDDRVHPGHARKMTAKLQAM----------GYD-TS-----FYEPAAGGHGYGTDNRER---------ASFITLGTRFLARHVGLEMD--------------------------     =====>
9burk-q3f8z7   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSFRW-----PAGADPFRFLESL--DSKRARAWVDEQNARTRVA-LRDDDAY-RA-LTARLAQAYLPR--ERPVIPTRW-REWAYDLWQDDLHPKGLWRRARWDDWRAG---------RPEWETLLDVDALGA----QEGESWVFEQDAILYPD----GDRALLSLSPGGADAVVVREFDLVQR-------------------------------RF-V---DDGFTIDEP-------GHHTVGWIDRD-----TVYVSWDRG---------EAHATAAGYPYDARR-----WVRGTPLADAP-VVFRGEP-DD-----IS---AGAAFDPIDGRH---------V-AW-RSVDFFD-AHAYWLNG-----------------AGEWVRYDV-PTH-VEVG-FWEGWLVLEPRLDWDCG----------------------GVRHAGGSLLAIREQAF----LA------GAR---ELTTLF--EPRPSTSAC-----TWT-HTR------TMLIASWLDDVQNRTMLWQPRQG--------DDGAWTW--------------------HARPFE-WPGDAQVDLE----------------------------PVESTLNDDVYVDVDTYLDPPECWLADLADRADD-AA-SRRVLL--DRP--PVRFDAAGLVVRRANAR-SRDGTAVPYTLIGPRDALDGLDH---PDGVTR-VARPCLLSGYGGFAIP-NLPGY------------------------SDALGIAWLE-------------------------RGGVAVFAHIRGGGEFGPGWHVDAQREHRQRAFDDFIAVAEDLIRSGVTTAAQLGIEGGSNGGLLVGACMVQRP--ELFGAVLCRVPLLDMRRYPKLH-AGAAWLDEYGDP-DD-SREGAALAAYSPYHRVR--------EGVVYPPLLLTTSTRDDRVHPAHARKMAARMHAL----------GHERVW-----YWENTDGGHGSADDL-ER---------AEADAAEFGFLWAHLGPAPAPARG----------------------     =====>
9burk-q457q5   	---------MPRSDII---------------------------------------------------------------------------AVCMQ--------------------------------------LAI------------------------PR-----------SSMSESFRW-----PAGADPFRFLEAL--DSKRARTWVDEQNARTRAA-LRDDDAY-RA-LTARLAKAYLPR--ERPVIPTRW-RDWAYDLWQDDLHPKGLWRRTRWADWRAG---------QPAWETLLDIDALGA----EEGESWVFEQEAILYPD----GDRVLLSLSPGGADAVVVREFDLVER-------------------------------RF-V---DGGFTIDAP-------GHHTVGWIDRD-----TVYVSWDRG---------EAHATAAGYPYEARR-----WVRGTALAEAP-VVFSGEP-DD-----IS---AGAWYDPIDRRH---------V-AW-RSVDFFD-AHAYWLTD-----------------AGEWARYDV-PTH-VEVG-FWEGWLVLEPRLDWDCD----------------------GVRHAGGSLLAIREEAF----LA------GAR---EFTTLF--APRPTTSAC-----TWT-HTR------TTLIASWLDDVHNRTMLWQPRQA--------DDGAWTW--------------------DARPFD-WPGDAQIDVE----------------------------PVESTLNDEVYVDVDTYLDPPECWLADLADRADD-AP-SRRVLL--DRP--PVQFDAAGLVVRRASAR-SRDGTVVPYTLIGPRDALDA------PEGVAC-VARPCLLSGYGGFAIP-NLPGY------------------------SDAFGIGWLE-------------------------RGGVMAFAHIRGGGEFGPRWHTDAQREHRQRSFDDFIAVAEDLVATGVTSAAQLGIEGGSNGGLLVAACMMQRP--ELFGAVLCRVPLLDMQRYPKLH-AGAAWLDEYGDP-DD-PREGAALAAYSPYHRVR--------EGVVYPPLLLTTSTRDDRVHPAHARKMAARMQAL----------GHERVW-----YWENTDGGHGSADDL-ER---------AEADAAEFGFLWAHLGPAPARR------------------------     =====>
9chlb-q43eh9   	----------------------------------------------------------------------------------------------------------------MTI------PRTALFLLCFLALTSAAF----AVEKPEPV----VIRKSFPEAQKP---VV------ETWCG-----ETIADPFRAMENI--RNPQVINWLKQESDYARNT-LQRIPGR-DS-LISKMQEFDKRKVSKVYNLSITENDVYFYLKQTPSDETGQLYYRK----------GFH-----GKETLLFNPSSS-P----DKESH-----TVIGTISPSFDGSKVAFTISKNGSEDAVLLIMDVATK-------------------------------KL-FPEKITRCR-----------FASP-SWLKTG----DAFLYNRLRA-LE-KP------GENPQHNSKTFL-----HIPGTDPSRDL-EIFSSATNPELVLNPEDIPEVS--YEKES-GQ---------L-FA-FLSNVDRRLTVYYAPLDQP---G--------KKKTAWKKLFI-PKDDVHD--------FAV---------------------TEKDIYFSSPKKASGFRLLKT---------------SLEHPDLEHAELIVPETP--GATLT-----GFT-LTS------RGIFYTQSKNGVEEKLYHQEYGKT----------------------------------ESKEII-LPSAAGTIAL----------------------------SSKGFRYPDLWVVIAGWSKDYRRYRYDSRNEGTF-SLETLSSPA-------LYPE-YERLKVEELMIP-SHDGVMVPLSIVYRNDL------------DKK-GTNPVLLYGYGAYGNA-LTPFF------------------------SPS-LLLWTH-------------------------KGGILAIVHARGGGELGDAWHTSGMKTTKPNTWKDLISSAEYLIKEKYSSSRHIAINGASAGGILVGKAMTERP--DLFAAAIPQVGLMNPLRGEETP-NGPVNVPEFGTV-KK-PDECKALIAMDPYLSIID--------GVRYPAALVTAGINDPRVSAWQPAKFAARLQAATA-------SNKP-VL-----LFTDFKAGHGMGNTKQME---------FESLADVLSFGLWQTGHPEFQIR-----------------------     =====>
9chlb-q4alz1   	--------------------------------------------------------------------------------------------------------------MKKAV------LLTSIFFFCLSSFSRQAQ----S---ETVI----PMQNTAEAPEKP---VT------EIYCG-----KKIVDRYRYMENL--KDPLVLQWFKTQEESARSV-MENIPGR-KS-LIEKMQDFDSRRSSKVYNLVITDNDRYFYLKRTPSDETGKLYYRE----------GYS-----GDERLLLDPSQLSK----KGTGN-----YVVSNISPDDDGSKVAISVAADGSEDDIVMIMNVKTG-------------------------------AL-YPEKIDRCR-----------FASP-SWLPDG----TAFLYNRLNK-GM-QG------DIDIQKNSRVYL-----HMVGTDPSTDR-EIFSGATNPDMNIRPEDIPFVH--YDKDS-AH---------L-FA-FIQNVDRRLFVYYAPVSEL---T--------ADRISWKKLFT-PEDNIHD--------FSV---------------------TETDLYLYTPDNAPNFKVLKT---------------SLLQPDISNAETVIAEHP--DAVLT-----SFT-ITS------KGIFYTQSKNGVEVEFFRLRTGKN----------------------------------KAEKIK-LPFKAGTLHL----------------------------TGKGFRFPEAWVVISGWGSDYKRYRYDEKSG-SF-IYETLSSPA-------EYPE-YEDLIVDEVMVP-SHDGVKVPLSLIYKKGL------------KKD-GKNPVLFYGYGAYGKS-LRPFF------------------------SPS-FLLWTH-------------------------KGGILAVAHVRGGGELGNAWHKAGMKSTKPNTWKDLISCTEYIIKNNYSTPDLIAINSASAGGILVGKAMTDRP--DLFAAVIPQVGAMNPLRGEETP-NGPVNAPEFGTV-KD-SLECLALIEMDPYLSITD--------GVRYPAALVTAGLNDPRVIAWQPAKFAARLQSATA-------SQRP-VL-----FYPDFQSGHGIGDTKTRQ---------FESLADVLSFAFWQTGHKEFQPEKQ---------------------     =====>
9eury-b7r0s6   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEYIWAENL--KDERVLKLVEEENKRFREF-IGGLS---DE-LFPEVWEYYSIP--TLVSAKLTEKGVVAMYR-----ERDRQIIRW----------L--------GGEVIVDSKELEK----ELNDEVLLQGFTADE-----KGKFLAYSFSIGGADEGITRIIDLETG-------------------------------EL-IEEFRPSVW--------------NVTFLDDG------YYFARFYRHGE-TP------DGVKAPAVRLF---------RKDRSGEK-LVFGEGL------GSGYFIGLS--KSTDGKWA---------M-IT-VTFG-WNSAEIYVGPIDEP---E------------KWEKVYS-ADVPVEP--------VDV---------------------RDGKLYLLTREGKGLGKLIAV---------------------GEKVEEVIPEGE--FP-LE-----WAV-LVG------DKILAGRLVHASHRLEVYSLDGEK-----------------------------------LDGIT-FDLPGSVYPL-------------------------------DTDGKRVLLRYESFTVPYRLYEFDGELKPVE-G-----------------QEIEGNFRVEEDFAL-SKDGTRIHYFLVK----------------GEK-DEKKAWVFGYGGFNIS-LTPRF------------------------FPQ-AIPFIK-------------------------RGGTFGMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKREGY----KVAAWGRSNGGLLVSATLVQRP--DVMDSALIGYPVIDMLRFHKLY-IGSVWIPEYGNP-DD-PRDREFLLKYSPYHNVKK---------QKYPPTLIYTGLHDDRVHPAHALKFFLKLKEV----------GAP-VY-----LRVETKSGHMGR-FTRDE---------GERAYRFARLRAQDPWLSYSSSIILFIQLP----------------     =====>
9eury-c1vd69   	---------------------------------------------------------------------------------------------------------------------------------------------------MDSP---------PETDQRD---TG------YTLHD-----DDIDDPYLWLEET--DD-DVSAWTAAQNDYADDY-LDSLDIR-ES-LRPRFEDLART---TTYMPVKARQNGYFQRVRDADADHPVLTFRP----------GLN-----EDRRVLGDPNEMSD----D--GS-----VSVDWYVPNPDGSLVAYGVAEGGDEQYDVRVLETESG-------------------------------ET-AEELTDVG--RT--------GPWCFGWTD------DGFYYLTTGSVG-----------DGGQLEKEVCF-----HEIGTDPADDW-TLAD-EF------STQTWPLVE--TDAESDYV---------I-LG-HTEG-WERTDLYYAELGSD----------------ELHPLVV-GEDALFE-------PTL----------------------DGNDVYVNTSLDASNYRVVSVSLDAVDPSASPTDVGESSTDPNKPFETVVAERD--DAIAQ-----ELD-VIG------DRIVVKYLRDAVHELVVFDADGE-----------------------------------QDETVP-LPGRGSVASF----------------------------G----GEDDLFFTYESFTEPPSIRRYAFGADETT-VVDQ-PDIS-------TE----TDLTVTQDWFA-SADGTEVPAFVVRRSDL------------ECD-GDNPAVLYGYGGFENS-LTPFF------------------------GEF-FLPFLE-------------------------SGGVLAVANLRGGGEFGESWHHAGRREHKQRVFDDFFAAAEHLVENGYTSTERLACFGGSNGGLLVGASITQRP--DLFAAAVCKVPLLDMLRFHTSL-LGETWTTEYGSP-DD-PEAYEYIREYSPYHNVEE---------RAYPAVLFTTGESDSRVDPFHARKMAARMQAAQS-------GADP-IL-----LKTRSQTGHGSGKPVSKV---------VEENLDEWSFLGDQLDAF----------------------------     =====>
9flao-q1vxy2   	--------------------------------------------------------------------------------------------------------------MKQIVLP---LAALCLLASCNE------------------GEKNQANLTYPE-TKQVD--------TVDTYFD-----TEVKDPYRWLEDD--RNAETEDWVKAQNEVTFGY-LDSIPFR-NK-LKERLSKVWNYE---KIGAPFERGK-YTYFSKNDGLQNQYVFYRYKNEDS---------I---ENAEVFLDPNTFSD----D--GT-----TSLAGMSFTEDGETLAYSISEGGSDWRKIIVLNTETM-------------------------------DR-KEDTLVDV------------KFSGVSWKGNE-----GFYYSSYDKPE-------GSELSAKTDQHKLYF-----HTMGTPQSGDE-VIFGATE-A----EKHRYVSGN--VTEDDRYL---------V-IS-ASISTSG-NKLMIKDLTNPD---S-------D----FIEVVD-NYD--------SDVYVI--------------------ENKGSKLFMVTDKDAPNKKIVTVEASAPQ---------------PENWEDFIPETE---HVLS-----P-S-TGA------GYFFAEYMVDAVSQVKQYNYE-GE----------------------------------LVRDIE-LPGVGSVGGF-----------------------------GGKKEAKDIYFSFTNYTTPGTIYKFTPENG-T--------YVVYQKPD---IDFDTEAYESKQVFYP-SKDGTKIPMIITHKKGI------------ELD-GTHPTMLYGYGGFNIS-LTPSF------------------------STA-NTVWLE-------------------------NGGVYAVANLRGGGEYGKEWHNAGIKMKKQNVFDDFIAAAEYLIAENYTSSNKLAIRGGSNGGLLVGATMTQRP--DLMQVALPAVGVLDMLRYHTFT-SGAGWAYDYGTS-QDSSEMFEYLKGYSPLHSIKD--------GTEYPATLVTTGDHDDRVVPAHSFKFAAELQSKQAG-------GAP-TL-----IRIETDAGHGAGKP-TSKI--------IQEYADIFAFTFYNMGYTEL--------------------------     =====>
9flao-q1vz51   	--------------------------------------------------------------------------------------------------------------MKN----------IIVFA-MVILFGTTVF----A------------QWDYPTTKKVE---VI------DTYFG-----IDYKDNYQWLEDL--TNPEVETWFKEQADFSNAT-MSKISGR-DE-LIAEWRKLDALQSA-TFSDLKKVGQRIFFKKRMPGDKVGKIYYRE----------TMD-----SPDILLFDPLNFKA----G--KT-----LSVESFIPSYDGKKLLIGYSESGAEISVLQVLDIDSN-------------------------------TF-LPDLIPATA-----------GAMGWTFDD------SAFMYMWIKS-TD-NK------DPEGRLNPKTKL-----HKLGTDYKTDV-DFFSNEAYPDMNIPSKAYPYIS--LSKNAKDF---------V-FA-GQGTVAKELILYYAPLDQF---N--------SGNIAWKILCK-ASNKLINGTSDQGGLPEV---------------------FGTKVYAITYKGAEKYKLIAT---------------DLKNPDWANAETVVAEKD---MSLT-----GYT-RSK------DYLLLNYS-DGINSHLFKFNPKTK----------------------------------TNTKIT-LPFMGIARAK----------------------------CL-DTKTNDFIIDLTSWNKPLTEFMLNAETETFT-A-SPFNQTN-------VYPDAYNELVVEEVEVK-GHDGVMIPLSIIYKKGT------------KKD-GSNVCFMRSYGAYGSS-ANPYF------------------------STL-YNALVT-------------------------KGVVYAVPHVRGGGEKGEAWYKGGFKTTKPNTWKDFISCAEYMIAQGFTQSSKLSGMGTSAGGILISRAITERP--DLFAAAINNVGTSNKMRGEFSA-NGPVNVPEFGTV-KD-PIEAKALYEMDGMQHVVD--------RVNYPAVINVAGWTDSRVVAWQPGKFAAALQNATA-------SNKP-VL-----MKVNYDNGHFTE-DREVT---------WANFADQFAFVMWQCGHPDFQQKL----------------------     =====>
9gamm-q2wwt8   	--------------------------------------------------------------------------------------------------------MAVRFHLAK--QGLLVATLGLALGACQSGNT----P---EQHSVEVQQASSNKFVYPE-TDKDD--------LVETIHG-----ISVADPYRHLEA---NTPETEKWVKTQQAFGQEY-LAKIPNK-QA-VVERITELWNYE---KVSAPFEHGE-NQFYYRNDGLQAQSVLYVKGR-------------D--GVEKPILDPNKLST----N--GT-----VALSGVSVSNDGKILAYGVSNSGSDWQQWQFINVATG-------------------------------KK-LSDELKWI------------KFSNAVWDKEN----QGVFYARYDAPAG------GDLLADVNFNQKVYY-----HTLGTDQRQDL-LIYERP--Q----NKDWGFKID--VSEQGEYL---------L-LS-ISQGTDKRNRFFYKSLFEPK---S-------Q----VVELIL-NLE--------AEYEFL--------------------GNDGSVFYFKTDLDAPNGKVIAIDTRNSD---------------KSQWQTIIPESK---DPIN-----NVA-IIN------DHLVVSYLHDVLGQLSIYSMG-GQ----------------------------------KRQDVA-LPGLGNVTGP-----------------------------FGKASKDYFYYVFNSYIQPETTYKFDFKTG-G--------STVIAKPK---VSFNPDNYISEQVFYT-SKDGTRVPMMLSYKKGL------------VKN-GQNPTLLYAYGGFAIS-MTPRF------------------------SPA-NIAWLD-------------------------MGGIYAVPSLRGGAEYGESWHQAGMFDKKQNVFDDYFAAAEYLINEKYTNTSKLGAYGRSNGGLLMGAAVTQRP--ELFAAVLPAVGVLDMLRFHKFT-IGWAWTSEYGSA-DN-AEQFPALLAYSPYHNVKA--------Q-SYPATMVMTADHDDRVVPLHSFKFAAMLQDKQQG-------DKP-VI-----MRIESNAGHGAGKP-TAMK--------IDEFADIYSFLWQSFGLKLPQTIAK---------------------     =====>
9gamm-q2x3h7   	--------------------------------------------------------------------------------------------------------------MNNKL------LP-----WCIAGVLGMSG------------------------------------------QL-----HAEEDKYIWLEDV--EGAKPMEWVKTQNAASAAE-IKAFKGF-DT-LVANSLAILNDK--ERIPYATHI-GDKLYNFWKDDTHVRGIYRRTTMEEYAKP---------DPKWETVLDIDALGK----AESVNWVFKDISCQYPE----NERCFVSLSRGGADAVEVREFNLNTK-------------------------------SF-VATKDKPFFLKE--------AKSSLSWIDKD-----HAFVGTDFGDG--Q----S--MTDSGYPREVKL-----WQRGTPLEQAK-PIFTGDK-TS-----VA---VSGWVLFDDKTP-------LSL-VT-EAHTFYT-ATQYVYQ-D-----------------GKLIKLPV-PED-AEIKGYFKGKLFIELKSDLTNK----------------------DGNFKQGAVVYADVADL----IA------QKA---KFSLFV--SPTQTASIA-----QLS-FSK------SAIFVNWLDNVKSKLVRYEQDE------------KGAW--------------------QSTQVP-FEANGAL---------------------------TV--MDVEQDSDDFFVNYTSFLEPSSLYTVNAKT--------LNPKKI--KGM--PQQFAADKFKTEQYFAT-SKDGTKVPYFVVMAKDL------------KLD-GTNPTLLYGYGGFEVS-LRPSY------------------------SATIGKNWLE-------------------------QGGVYVLSNIRGGGEYGPAWHQAALKQNRHKAYEDFEAIAEDLIARKITSSKHLGIQGGSNGGLLMGAAFTRRP--DLYNAVVCQVPLLDMLRFNKLL-AGASWMGEYGNP-DI-PEEWAYIKTYSPYHNLH--------KDVHYPKVFFTTSTRDDRVHPGHARKMVAKMKDM----------GID-VL-----YYENIEGGHAGAADNNQA---------AELNAMTFAYLLQRLR------------------------------     =====>
9gamm-q3nyp6   	--------------------------------------------------------------------------------------------------------------MNKAL------VS-----LCVLSAITAGQ----AL--------------AEP--A------SEQKASAKNAKT-----AVQADKFLWLEEV--EGTKPLAWVKDKNAHSATS-IKSYPGF-DT-LVNNSLAILNSK--DRIPYAERK-GEYLYNFWKDETHVRGIYRRTSLAEYVKD---------EPKWETVLDIDAIAK----ADDVSWVYKDINCLAPK----NDLCLVSLSRGGADAVEVREFNLTTK-------------------------------SF-VK---QGYRLPE--------AKSDLTWLTQD-----QVLVATDFGGE--Q----G--MTDSGYPSVVKL-----WQRGDSLDKAK-FIYQADK-SS-----VA---AAAQVLDDGQSK-------VVL-IG-DYLTFYT-NKVFVYA-D-----------------DKLTKLNI-PQD-ADIKGYFKGNIYIELKSVLNTD----------------------KQQFVQGAVLYAPVDSL----MS------DKP---EYQQLT--APDAHSSIA-----QVA-FSK------NAVYVNLLEDVKSKLVRFEPKD------------DNNW--------------------TQTTVP-FDANGSL---------------------------TL--FDIQQDSDDFFVDYNSFLEPSSFYQVKGAA--------LAINKL--KSL--PQQFAADKFVTKQYFAT-SKDGTKVPYFVVMDKNL------------KFN-GKNPTLLYGYGGFEVS-LKPKY------------------------SADMGKNWLE-------------------------QGGVYVLSNIRGGGEYGPAWHQAALKHNRHKAYEDFEAVAEDLISRKITSSPHLGIQGGSNGGLLMGAALTRRP--ELYNAVVCQVPLLDMQRFSQLL-AGASWMGEYGNP-EV-AEDWAYIKTYSPYHNLD--------KAKQYPKAFFTTSTRDDRVHPAHARKMVAKMESM----------GID-VL-----YYENMEGGHSGTADNQQK---------AELTSLVYAYLLQQLK------------------------------     =====>
9gamm-q3qdu6   	--------------------------------------------------------------------------------------------------------------MNKRI------LL-----LGAASLLAF--------------------------------------------NA-----VAQGDPFIWLEDV--EGEKALAWVKTQNDRSLAE-LKAVPGY-NA-LVDNALDILNDK--ARIPYASRI-GDHLYNFWKDEANPRGIYRRTTMAEYVKD---------APKWETVLDIDALGK----SEGVNWVFKGMDCQYPK----NIRCLVSLSRGGADAVEIREFDLSTL-------------------------------SF-VPADKQGFFLPE--------AKSSTSWIDEN-----TLFVGTDFDEG--D----A--WTDSGYPRKVKV-----WKRGTDLKDAK-EIYAGNK-AS-----VA---ASGYVMWDDKTP-------LQL-VS-EAETFYE-ASYKALL-D-----------------GKLVELPL-PKD-AELKGFFKGDIFVELKSKLEQG----------------------NNSFPQGAIVYTKADKL----LA------GTP---EFALFV--KPDANSSIS-----QVT-FSR------NAVLVNWLEDVKSKLVRYHKDA------------KGQW--------------------QGEDVG-FPSNGSI---------------------------SV--FDSSRDRDDLFVTYTSFLEPSTLYSVNAET--------LKRDSL--KAM--PAQFDASKFEAKQYFAT-SKDGTKVPYFAVMAKDI------------KLD-STNPTLLYGYGGFEVS-LRPFY------------------------SATTGKNWLE-------------------------QGGVYVLANIRGGGEYGPGWHQAALKENRHKAYEDFEAIAEDLIKRKITSPKHLGIQGGSNGGLLMGAAFTRRP--DLYNAVVCQVPLLDMKRYNKLL-AGASWMGEYGNP-DI-AAEWDYIKTFSPYHNLK--------KDVEYPKVFFTTSTRDDRVHPGHARKMVAKMEDM----------GIE-VL-----YFENMEGGHAGAADNKQT---------AELNSLAYAYLLKQLKL-----------------------------     =====>
9gamm-q3qef8   	----------------------------------------------------------------------------------------------------------MTSRIST--LSLLTLGFALGLSGCHTKDA----T----------VDAPVAAIAYPA-SQTVA--------ISEQIHG-----VEVQDPYRWLEE---SSPETEDWVKRQQAFGEEY-LAAIPNK-QV-VVDRITELWNFE---KVGAPFEHGE-NRFIFRNNGLQSQNVLYVSEK-------------G--GDERVLLDPNTLSA----D--GT-----VALSGVSVSGDGKTLAYGVSKSGSDWQEWAFIDVATG-------------------------------RK-LADSLNWI------------KFSRAEWAHDN----SGVYYSRYDAPAG------GDILVDVNYNQKVYF-----HRIGDEQAKDT-LVYERP--D----QPEWGFSST--VSDDGNFL---------L-IS-VSVGTDSRNRFFYKPLKDKS---L-------K----VVELMS-ELE--------AEYQFL--------------------GNEGPVFYFKTDLDAPRGRIIAVDTRNPA---------------KDNWRTLVPESQ---DPIA-----EVS-IIS------EHLVVSYLHDVLGQLSIYNMD-GV----------------------------------KREDVP-LPGKGKIAGP-----------------------------YGKASKPYFYYIFNSYVQPQTIYKYDLNKG-T--------NEVFSAPK---VSFNPDDYVSEQVFYT-SKDGTRIPMLVSYKKGL------------KKD-GKNPTLLYAYGGFSIS-MTPRF------------------------SPA-TIAWLD-------------------------MGGIYAVPALRGGSEYGEEWHKAGMFGKKQNVFDDYFAAAEYLISENYTNSSKLGAYGRSNGGLLMGAAVTQRP--DLFAAILPAVGVLDMLRFQKFT-IGWAWTAEYGSA-DN-AEDFPYLLAYSPYHNVKA--------Q-TYPATMVMTADHDDRVVPLHSFKFGAMLQAKQQG-------QAP-VI-----MRIESKAGHGAGKP-TAMQ--------IAEFADIYAFLWQNFGLTLPTEL-----------------------     =====>
9gamm-q6ivm6   	--------------------------------------------------------------------------------------------------------------M---YKLCLNIFLILIISSCS---------------------NQ-NTSGYPE-TKKEE--------FSETIHG-----YEISDSYRWLEDF--TSDDSLDWVKRQNKFTKTF-ISKNKYK-KN-IASYLEQIWENE---SISIPYKEEG-KTFYYFNDGSFQQSKLMIKDC------------DK--CDERVLIDPNTFSD----D--GT-----ISLGGTSVNNSADMIAFSISDGGSDWRVWKVLDIETG-------------------------------EV-LEDEIKWA------------KFSGASWENDD----SGFFYQKYDEPQG-------ELLKEVNESPKLMF-----HKIGTDQSEDY-VVYENP--D----QPRWGWGIN--VIEDTNIK---------I-LS-ISEGTDERNRLYIQLNAG-----E-------K----FIPLID-ELI--------GAYSFI--------------------DSKDGILWFYTTEGAPNGKIVNLEIKNGSF----------------VWNDVIQESE---NSIR-----SVN-VVN------NSFVINYLVDTFSSIKIFDLS-GN----------------------------------FVQDLE-LPKNGTIGGF-----------------------------GGEIDDTETYFSVSNYVTPREIYEINLDSLDV--------KLFWKEEI---DGYESEDYVSELKFYP-SKDGTKIPIHISYKKGL------------EIN-QDTPLMLYGYGGFNIS-LLPGF------------------------RKT-HAAWKN-------------------------LGGVYAVANLRGGGEYGSEWHEAGMLLNKQNVFDDFAFAAKFLHENNIGSEKTTAIIGGSNGGLLVAATMLQNP--DLFKVAIPQVGVLDMLRFSKFT-IGWAWESDYGSV-DK-KDEFENLLAYSPLHNIEK--------DKCYPTTLVTTASRDDRVVPSHSYKFAAKLQEYQGC-------QNP-IL-----IRIEDRAGHGAGTP-KDKI--------INQISEIYGYALNSINN-----------------------------     =====>
9gamm-q6q963   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDMK---------L-LS-ISEGTDDRNKVYLKINEN-----S-------D----FIPIID-ELI--------GTYSFI--------------------DSKDNLLWFYTTESAPNGKIVNLEIKNGSF----------------VWNEVIAESE---NAIR-----SVN-IIN------NSFVINYLEDTFSQISIFDLS-GE----------------------------------FVSKLS-LPKKGTVSGF-----------------------------GGDIDDKESYFSITNYITPREIYQIDLTDNSF--------KLFWNEEL---DGYNSEDYVSSLQFYS-SKDGTKIPIHISHKKDL------------VID-ENTPLLIYGYGGFNIS-ILPNF------------------------SKS-QTAWKN-------------------------QNGVFAVANLRGGSEYGDAWHEAGMLLNKQNVFDDFAYAAKFLHSKKIGSPETTAIDGRSNGGLLVAATMLQNP--DLFKVAIPQVGVLDMLRFNKFT-IGWAWESDYGSS-EK-KDEFENLLAYSPLHNIKS--------DVCYPTTLITTASRDDRVVPSHSFKFAAKLQEYQSC-------NNP-IL-----IRVEDRAGHGAGTP-KDKR--------INQISEIYGYALNVINN-----------------------------     =====>
9micc-q4nej3   	---------MPR----------------------------------------GPAPISTVRMFCDV----PTP-----------SRV----SACDLLA----------------A------RR-----CCFVGRMTTTA----AD--------------HPP----------ASGAPSAAGKA-----PEPTDENIWLEEI--YGEAPLAWVREQNARTEDL-LE-DADY-AR-LESRILEVLDST--DKIAMVGKH-GDWYYNFWRDGQNPKGLWRRTSWESYKSG---------EPAWDVLLDVDALAA----AEGEEWVFHGANFLRPAPGEPHRLALLALSPDGGDANRYREFDVETR-------------------------------TF-VDPASGGFDLPT--------AKGNASWLDRD-----TLLVSTTAEGM-------P--KTSSSYARTAVK-----LARGGSLPAAE-RIFDIPE-DH-----MM---ALVAHDSTPGYE-------RTF-AM-DWISFFN-KSTSVLH-D-----------------GQWVVIDA-PTD-VNLS-VHREWLLFRPQGDWAVD----------------------GTTFPAGSLLAAKFEDY----LA------GNR---ELVVLF--TPDAHTSLQ-----SWS-WTR------NFLLLNLLRDVSSEIRVLDPERP---------GTESAW--------------------ASSLLDACPPLHDVNAFAVDDEDDSVEVDEEHDDDGTGGNVAVPEGEAPGAGNDFWLVATGFTTPSTLTRGTLRRSGDG-DVVSTHEVV--RTS--PSYFDEAAYEVQQHFAV-SEDGTRVPYFQVASKNL------------VLD-GQNPTQLSGYGGFEVS-RTPAY------------------------SGTIGRAWLERRTDAPDAPDAGQGDAESGAGPTHTRGGVYVVANIRGGGEYGPSWHRAALQENRHRAFEDFAAVARDLISRGVTSRERLGCVGGSNGGLLVGNMLTRYP--ELFGAVSCGVPLLDMRRYTKLS-AGHSWIAEYGDP-DV-AGDWEFIRTFSPYHLLR--------DGVDYPETFIWTATSDDRVGPVQARKMAARMQAM----------GIPNVW-----FHEALEGGHAGASDNRQA---------AALQSRSQHFLWRSLAGRSGS-------------------------     =====>
9myco-q1tu32   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVDDAHLWLEDI--TGDDALDWVRRHNEPTLAD-LG-GERF-EQ-MRAEALEVLDTD--ARIPYVRRR-GEYLYNFWRDAANPRGLWRRTTLESYRTE---------EPDWEVVIDVDALAR----ADDENWVWAGADVIDPD----HTRALISLSRGGADAAIVREFDMVSM-------------------------------EF-V---DGGFELPE--------AKTAITWEDED-----TVLVGTDFGEG-------A--LTESGYPRLVKR-----WRRGTPLTEAE-TVYSGEP-AD-----VI---VTASVDRTPGFE-------RTV-VR-RAVDFFN-DEVYELRAG-----------------ELSR-IDA-PTD-ATVS-AHRDWLLIELRSDWD--------------------------GYRAGSLLAAKYDEY----LD------GTR---ALQVVF--EPDEHTCLH-----HYA-WTK------DRLVVVTLADVASRVEVYTP---------------GEW--------------------TAQPVPGLPDNTNT---------------------------VIV-A-ADDLGDEIFLDSSGFDTPSRLLQGAAGG---------ELTEI--KRA--PSFFDAADLKVDQHFAT-SADGTKIPYFVVGHR--------------HQQ-APGPTLLGGYGGFEVA-RTPGY------------------------DGVLGRLWLS-------------------------RGGTYVLANIRGGGEYGPTWHTQAMREGRHLVGEDFAAVAADLVERGITTVDRLGAQGGSNGGLLMGIMLTQYP--ELFGALVCSVPLLDMRRFHLLL-AGASWVAEYGNP-DD-PDDWEFISKYSPYQNIS--------AERRYPPVLITTSTRDDRVHPGHARKMTAALEDA----------GQP-VQ-----YYENIEGGHGGAADNSQA---------AFRAALIYEFLWRKLGG-----------------------------     =====>
9sphn-q1n9q7   	--------------------------------------------------------------------------------------------------------------MK--------------------RILTLVS----AA---------------L----------LTGAGAPPASTA-----NPSDDPYIWLEDW--TGPRAMQWVEAENKATEAA-FQNDPRY-AG-YYRDALAIASAK--DRIAMPMQV-HGRVYNFWRDADHPQGIWRWTSEADYATD---------TPNWTTVLDLDALSK----AEGKKWVWKGASILDPD----ERLALINLSDGGEDAVSLREFDLETG-------------------------------KF-V---DGGFAIPT--------SKQNEAWLDRD-----TILIARDWGDG-------T--MTKSGYPFVVKT-----LKRGEPLSSAR-EIYRGAP-SD------QV-GTFPLILSDGSGN-------RAAFLY-RGVTFFS-NETYLVDGA------------------EVKRLPL-PAK-SNLQGMVDGQVLIQTSEAWQSG----------------------GVSVPTGSLVAVPL-----KAL-------QSGETLKPQILF--APSPRQSID-----GVA-ATK------GHVILAYNDNVRGRVMVLTPGA-------------DGW--------------------SQTPVE-LPDNATI---------------------------SI--ASASDKSDKAYLSVAGFLAPTTLWAMDAAN--------PAPTQV--KAM--PARFDADGLVVEQFEAT-SSDGTKIPYFIVHARDM------------KKD-GSTPTIMTAYGGFEIP-MTPSY------------------------AAITGKLWLE-------------------------RGNSFVLANIRGGGEFGPAWHEAGLKTKRQIIYDDFAAVAQDIFARKLSSPDKFGIYGGSNGGLLMGVEFNQHP--DLWNAVVIQVPLLDMIRYEQIA-AGASWVDEYGSV-SV-PAEKAFLQTISPYANIR--------KGVDYPTPYIWTTTKDDRVGPQHARKFAARLKEY----------GIP-YH-----FYEDTAGGHSGDADIKQG---------ARLQAMQMVYFSQQLEGKASKQK-----------------------     =====>
9sphn-q1nec1   	------------------------------------MRG-----------------------FAL---------------------------------------ILLSLWLAAAP-------AMLRAH-----------------PDDAAIAASDPALRYPL-ARRQD--------IVEDHFG-----VPVADPYRWLENDLRADPAVRDWVARENALTRRY-LDALPGR-EA-LKARLQALFAHG---RYTVPRKAGD-RYFYGYNRGLENQTPLYVREG------------LT--GRQRLLLDPNSWAQ----D--GA-----SALAEWTPSPDGRMLAYGVQDAGSDWRTLRLIDVDSG-------------------------------RT-LDDAVQWV------------KFSQTAWDGRS----EGFFYSRFAAPGP------GETFRSTNLGQSLYY-----HRIGTSQGQDQ-LIYATP--D----RPRLSHQAQ--VTADGRWL---------V-VS-SFEGIDPRREIHVAPLTGG--PI--------V----LRRLVR-GPA--------QDWRLI--------------------GSRGSTLYFLTDHRAPHRRVVTLDAANPRR----------------RAQEIVPERA---QTLV-----GGA-LVG------DRLILASMNGAQTIAELVELD-GR----------------------------------RVGDVP-LPGFGTAAGF-----------------------------GGRSGDPETFFSFSGFVTPASIYRFDTATR-Q--------FQLFAQPD---LPFDPNDYGIEQRLYP-SKDGTMIPLTILRKRAL------------ADSATAAPTILYGYGGFNIS-LTPGY------------------------SAT-RMAWLE-------------------------QGGVYAIANLRGGGEFGRAWHDAGRGANKQNVFDDFIAAAEYLKANGFTPPDGLAIEGRSNGGLLVGAVVNQRP--DLFAAALPAVGVMDMLRFDRFT-AGRYWTDDYGSP-AD-RRAFPLLYGYSPYHNIAG--------GSDYPAILVSTADTDDRVVPAHSFKYAAALQAADLG-------ARP-RL-----LRVESRAGHGAGKP-VDKL--------IDEYADSYAFAAHFTGLAIAPRPAAAPRSAAGQPAHVMAPIVAGGQ     =====>
9sphn-q2n8z0   	--------------------------------------------------------------------------------------MKFTS-------------------MQ--------------------A-LAAGL----AL--------------ATAVSPLDAQ--DSNTV--LEPEY-----EAENDPFIWLEET--RSDRALEWVRGENAKTEEA-LQSDPRF-EE-LKAEALAIYNAD--DRVPSISFTHYG-RVNFWQDADNPKGILRRTTMESWRTD---------DPQWETILDIDALAA----AEGKEWVYGGMTCLPPD----GTRCMVYLSDGG