MSA from Cobalt (Ncbi)
Cobalt
Color code Main amino-acide (aa) at this position Non majority aa at this position 50% conservation Catalytic site Catalytic site in alignement
Position ....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....620..5....630..5....
9bact-d6ulw3 --------------------------------------------------------------------------MRRL-------I-----------------------------------LILVSLGCAAVA-P-------LSAQSTARVGLATRVFHPEQRRNWRGAEHKELRCTIWYPAASTA-TE---------TKQLIG------PPDEPL---FEAGSAAL-NAEFA------PALRKLPLVLLSHGSG--GSAEQFAWLGTALARAGYIAVAVDHPGNNSH---EP-YTSEGFIL-SWERATDLSEVLDGVLAD-AEFGPHIDPQRVGAAGFSIGGYAVMEIAGAQTDISILFDFCK-E---HP-DT--TSCHVPEMR------------GMGSPKE----MLQAVRKSSRESLARSGESFRDERVQAVFAIAPAN-GM--VLT-DESLRAMRLPVEMVVGKTDP--IADPRDN----ANWI---H--MNVR-GSRETLLSGGVEHYTFLDTCTAAG----KSKLG---VYCADN-----AGVNRDAVHAQVAAMAVKFFDRALKAR------------------------------------------------------ =====>
9bact-d8v1j6 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKAVWYTVLAML-LL---------LTSCVK------VPDGTLQDDLRNREIKF-AVWVP------ESTEPAPLIVLSHGSG--GHYSNFNWLTRVLVEHGYVVAAVNHPFNTTG---N--DTPEGVAR-AWDRPPDLSLLISELLSN-PEWAAAIDSTRIGATGFSSGGYTVLALAGAVYDIDQMHAYCN-S---TE-AG--PECGLAVAL------------PA--------------------ADPDASSLLKDPRIKAVFAMAPGW-GA--ATR-SDSLEAIDIPVKIVAAEDDE--ILIPAHH----AVYF---D--ELIP-DSVLV-MLPKGGHFIFLSCSPMTRVADWFIDRF---NLCGIG-----IDVDRDAVQKETAALAVQFFDQHLRAVE----------------------------------------------------- =====>
9burk-b5wcg5 ------------------------------------------------------------------------------------------------------MQ-R----IVRL-----MAIVAAV-----LA------LMPAAPVLAVDVGFEEVHI-------PNG-AEPPLTAGIWYPTTAPA-TP-----------HPLG------NA--------TQ-TVAP-HASIE------G--QHLPLVVLSHGGG--GWYGGHYDTALALAHAGFVAAAVSHAGDTFD---DQ-SRVLQLW----RRPAQLHRLVDYMLGD-WHGHARLDAARVGVFGFSNGGFTALVAAGGIPDLSKIAPFCE-----LH-P-DHDLCAALRRA------------G--------------VDVHFGAN-VPASAWVHDPRIKAVVIAAPSF-GF--VFG-RAGLSGVRAPVQLWSAADDR--HQPHPWY----DEPV---R--DDLP-RAPTWHVVPNAGHYDFLPPCDARL----ARLRP---EICDSK-----PGFDRAAFHERFNADVVKSFEAMLH-------------------------------------------------------- =====>
9burk-b5wt44 -------------------------------------------------------------------------MMRRG-------CAALS----SAVVVSLTVA-F----AGAL-----SGAIGASLPAHAA---------AQSAPAGWHVGETLRVFHPAVARNWRGAQTEALITRIWYPADRTQ-PE---------TPHDIG------APGHPI---FLGHAAAD-DAPLS------AAQPAYPLLLLSHGTG--GSADSLDWLAASLAAQGYIVAGVNHPGNNAL---EP-RTRDGFIL-WWERATDLSEVLDGMLAD-PRFGPRVDTARIGAVGFSLGGYTVLELAGARTDQAAFERFCR-S---PE-AD--AICTPPEAA------------SLAHA-----LTVAGLSAEAQASRARSGDSYRDPRIKAAFAIAPAL-GE--AFN-RSSFKEVTIPVALLAGEADT--IAPVNTN----IHRI---A--GFMP-Q-AKVTMVPGASHDTFLDVCEPEV----MERLA---EICKDG-----PGVDRAAIHARTAAQVRDFFAATLPAGGS---------------------------------------------------- =====>
9caul-e8rre1 ---------------------------------------------------------------------------------------------------------M----RCHL-----FFALFSLFAAFGAI------AHAEAPSASPQVGFRKTVT------------AQGVEVGVWFPAAGTP-AR-----------QSLG------LY--------SH-VVVP-NAAPL------P--GTHPLIVMSHGTG--GIFSGHVDTAVALAKAGFVVAALTHPGDNWQ---DT-SRATQIE----DRPKALNQLITYMLTE-APERDVIDPQRVGAFGFSAGGFTVLAAAGGRPNFARLIPHCQ-----AH-P-AYFDCQMIAR------------------------------HPRPATAVAAPSMPADTRIKALVVAAPAL-GF--TFA--EGLKGLRLPVQLWRADADE--ILPAPDY----ADAV---R--QALP-QTPEFHAVPNAGHFDFLAPCVDV------NLAP---QICSSR-----AGFDRAAFHDAFNAEVVRFFSQSLR-------------------------------------------------------- =====>
9delt-b6wwd3 ------------------------------------------------------------------------------------------------------MP-VRS----AV-----IMALLCLFI--TV---------PALADNGYNPGFRTLGF-------WQQESGIRVDVNVWYPSVRAP-RS-----------LSYA------PW--------TI-RGAR-NGKPV------P--GRFPLILLSHPSS--GTRFSFHDTAAALAARGFVVAAPTHPRDCME---NM-DHLFLWGQ-LKDRALELSATMDLLLAD-KDIGPSIDPKRIGVLGYGSGATAALLLGGALPDCSGWMDYCRKA-P-----QDDAYCYDQPRA------------R---MD--------SMCGHFPLD----PRSLTDPRVKAIAAVGPTF-GM--LFS-HQGLAGLQPHLLLVGLEHDD--LSISSLH----AEAL---Y--ERMD-RKPAHLFLDGADMSLLMAPCPPSL----ANELP---EMCHDE-----LDPLRQQLFNTLTRRLAAFFLEWLGTQEGPENFFSLGTGE----------------------------------------- =====>
9delt-d9y954 ---------------------------------------------MYRKP-ACGTTT---PMPRYLSE-----QTPFAHPPLLGACSALGCGRQRPPGRRAFSP-YHIRLFIPL-----LFFLLSAVP--AG---------SAAAADSYQVGFRTLGQ-------WSADTNLRLDVNIWYPSLRPP-RE-----------LNYA------PW--------TI-AAAR-NGKPV------E--GRFPLLLLSHASP--GTRFSYHDTAAWLASCGFVVAAPTHSQDCMD---NM-SLLFTWRQ-LETRAKELSSTLDLLLAD-QELAASIDKNRIGLLGFGTGGTAALLLGGALPDCASWPEYCAKA-G-----RRDMYCNRWARD------------R---VN--------AICQSLPLT-----ESLADPRIKAVAAAAPGF-GM--LFS-PASFRYFYPPLLLIAAESDA--MNRPSLH----ADAI---A--RLLN-GKARYLSLPGADTGALMSPCPEAL----AAELP---ELCRSV-----SPEERRAIHRHMDDALSDFFLHVLGSGKNLPVIPPPPDLTPPPP------------------------------------- =====>
9entr-e0lt46 -------------------------------------------------------------------------------------------------------M-LFRAAF--------IALSVLI---IS-------------LQAHATPGFRQVTL-------KG-DQGVPLNVAVWYPAAVQKGVS-----------ETVG--------GNAA---FVGTDIIR-DAVPA--------SGKHPLLLISHGFN--GSWRNLSWLASAMAAQGYIVAAPDHPGTTTF---NH--NPEDARK-LWRRPGEISRVIDFVSQS-SELTGTADPARIAAAGHSLGGWTVMSLAGARFDPLRLLHDCQ-----RH-V-LRGDCKLTTRL------------GIDDA---------------S-ARNVFLSDWQDKRIKAVVSLDAGL-AP--GFT-PVSLSKINIPVLILAAGNGMMGELPAPEE----SEYL---A--NQMRVSLRKYILIKGATHFSFMQICKPGAEKIIDDESPGDGIVCHDD-----KDADRTALHQTITTEITVFLNSVLNYQAPAGEINAEKVLKAAETHD----------------------------------- =====>
9gamm-a3y6w1 ------------------------------------------------------------------------------------------------------MK-TFIFLI-------ISIVLVLF---SN-------------LISAHQIGFSQLQL-------TK-NPERILEISLWYPAAKEAQFSQSKTANDTLKQVLIA--------DNIA---FKGTQVIK-SAPLLLQTSKAGGTQKRPLVLLSHGYR--GSWRNLNWLASKLVQKGFIAVAVNHPGTTTF---NT--SAIQAAK-WWERPKDIKHTLDYLLND-SIWQQDIDENKISAIGHSLGGWTVMQLVGAQFNREDYLADCE-----AL-A-SFRSCQIKEEL------------GLAFK---------------Q-NNEPESTQLVDSRIKNAIILDLGL-AR--SFS-QTSLNKLNSPVLILAAGIDIG-DLPQAQE----SGFL---A--EHLNLKNCRYKVYEKATHFSFMQECKPNAIAILEEEAKGDGIICKDG-----VGSTRAALHDTMFEDILAFLKQDN--------------------------------------------------------- =====>
9gamm-a5kx18 ------------------------------------------------------------------------------------------------------MK-WTHLLF-------T--PLLLL---CN-------------SAVAFDVGFTQVTL-------TD-DPNRPLNTAIWYPTSDK------------SDTTLIG--------DNPA---FIGTQIIR-DGEVQ--------SGTFPVVLLSHGYR--GNWRNQNWLATKLASRGYIVAAAGHPGTTSF---DQ--SPEQAAK-WWERPRDVSRMLDYLLSE-TSWKQSANVDNITAIGHSLGGWTVMQLAGAKIDRSTFESECK-----QY-N-NPRTCGLAEEL------------GLSKV---------------Q-AKESNNKDLSDPRIQRVVSLDLGL-AR--SFS-VGSLNRITVPTLILAAGIDIG-DLPQTLE----SGYI---A--EHMPLNSRRYKVYENATHFSFIQGCKPGAIPLLNEEVPGDGIICKDG-----IGTSRDQLHKLFFNDIARFLNR----------------------------------------------------------- =====>
9gamm-a6f6u3 ------------------------------------------------------------------------------------------------------MK-LSAVLI-------I--IFLCI---IK-------------VASACSVGFQQFQL-------SD-NVSRPLDVTIWYPTSQN------------SASISVS--------ENIA---FVGTKVIK-NASLP--------PKKHPLVLLSHGYR--GSWRNLNWLANELAIKGFVVAAPNHPGTTTF---DH--SALQASQ-WWQRPHDLVRVLDHLLED-TAWRTVIDTESVSAIGHSMGGWSVMQLVGAKFDRNTFQKQCR-----LY-P-NPRTCGLGNEL------------GLTSP---------------Q-PGEPKSFNFYDPRIKKAIILDLGL-AR--SFS-IESMSKVNTPVLILGAGIDIG-DLPQTME----SGYL---A--EHLPLFNRHYKVYEQAMHFSFMQLCKPNAIALIEEETPGDGIVCKDG-----AGIKRQELHTQIFKDILGFITYSQQINHM---------------------------------------------------- =====>
9gamm-b8l7s7 ----------------------------------------------------------------------------------------------------MKMR-M----KAAV-----LGMILTGLATVAA------------AHETGLAGERHGTTTVNSAAVRDVQHRDVLRYTVWYPAQAGS-RE---------TALTIG------PPDAPL---FDVGRAAL-DAPVA------G--KRLPTLLLSHGNG--GSARMMGWLGTALARAGYLVIAVDHPGNNGA---DA-MTLPGSVL-SWLRADDLRAALAAVQAD-PVLGAHVDRGRLGVVGFSAGGYTALLAAGARPDLQRLLAFCR-T---HP-DD--GVCRPQQEA------------ATHTMEA---RLAAAASPALAPWISHSDDARAIPGVRAVFLLAPAI-VQ--AFA-PGQLSSLQLPVSIVLGDADK--VAPPTSN----GEAA---Q--ALIP-GATL-LRLADVGHYDFLSTCTAAG----VQRLP---DLCTA-------ATSRAGTHQRTVDAATGFFDAALREPHDNEPLHLR--------------------------------------------- =====>
9gamm-q1zdx1 -----------------------------------------------------------------------------------------------------------------------------------MV------VEQKKSNSSDWVGSKTVQI-------TDNIEHISFDTWLLYPCIDKP-QS-----------VDVG------PY--------CI-NVCA-DGRIA------K--GEFPLVIISHGSG--GSHLLYRLIALHLVKNGYIVAMLKHHANNRD---DN-SLAEQDKN-LTLRTRHIRYVIDTLLSD-EQWMDVINPRKIFMIGHSMGGCTALALAGATPWSQHRL---------------------------------------------------------------KIDVSNDKRIRALVLLAPAS-AW--YQH-PNSFVNVNLPMLIFSAEHDV--ITPF-WQ----ADLI---KQKVSNS-ALVDLKVIKNAGHFSFISPFPAGM----VNKNF---AASQDP-----EGFDRNAFHDDLKKEISAFFNNQLNTTHSVIKD------------------------------------------------ =====>
9rals-e2sus9 --------------------------------------------------------------------------MLHR-------CL-----------------------AAAL--------AAVVMGAAHGG-P------ADAPAAPFHVGETTRTFHPQAERHWRGARTQALITNIWYPVDISV-PE---------VSHNVD------APGRSP---FRMQPSAG-KAPVA------STQAQHPLLLLSHGTG--GTASSLDWMAAALAANGYIVAGVNHPGNTAL---EP-LTRDGFML-WWERATDVSEVLDGVLAD-PVLGAHVDRTRIGAVGFSLGGYTVLELAGARTDVPAFMAFCG-S---PQ-AD--AICHPPEMA------------RAQINPT----VDTTRSPQTEASLARSGASYRDARIKAVFAMAPAL-GM--AMD-ATSLGNISIPVSLMAGDADI--TVPVDTN----VRRV---A--KMLP-K-ADLLLVPGASHYTFMDTCLPGA----APHVP---LLCKDN-----PGVDRDAVHAEAVRRALDFFGAALPGQT----------------------------------------------------- =====>
9rhiz-a9dca3 -----------------------------------------------------------------------------------------------M---TMTFRTTI--SSLATT----LAATLAM---NM--------SLNLAAAASELVGTRDITV-------FSVERQMDLPVTIWYPASHG-PEA-----------SIVG--------ENRV---FEGTPASV-GAEPE--------TGRHPLILLSHGSG--STVQAMGWLAAHLAKAGFIVAGPNHPRTTSG---DS--TPADTPL-LWQRVDDLSSIITALSAS-QDWGGIVDNERIGVLGFSLGGAAAMKISGARAGLEAYAGYCD-----TW-P-DMPDCRWFAGGIAYADWEMIEVEPLDLR---------------TIDKGLFERQNRDPRIKSAVLVDPSV-AQ--AFD-AESLRQIDIPMAFINLGAPQ--SIIAGVD----SSEL---A--G--LTPHGSLSHIDQAIHFSFLAECRQDAKAFLKQIGEVD-PICDDG-----GNRSRADIHTELKQMIATLFTSTLMNT---Q-------------------------------------------------- =====>
9rhob-a0ntf3 --------------------------------------------------------------------------MYPS---S---N--------RL-VRPIRLF-WFAASL--------AG-ALSL---AT--------GALAEDTLRYGPGVTKITI-------GDARKDRPLEGDIWYPTATP-DIL-----------PRAD--------TSKV---WQMALADP-DGKAA--------EGIFPLVVVSHGMY--GNTFNQAWLGSELARRGYFVAMVNHPGTSSF---LR--DPDQTRK-LWDRPVDLSRLISFLIED-SPYKDRIDPERIYAAGHSLGGFTVLLLAGAEFEPDRYERECS-----GE-E-LPLACQVLTGW------------SIAKT---------------EDDRSEMAKSRKDPRLTKVISLDLGG-TP--VLS-RDSLSAIDIPVLVLGSQRADM--LNQEIE----SRAL---A--AALPADKVHHVELANAGHFDFMGVCKPEGFAILEEYEPGDEIVCIKG------SKEREEQHQRILAEILAFLEP----------------------------------------------------------- =====>
9rhob-a0ny81 --------------------------------------------------------------------------------------------------------------MKIQT----LFWPLVL---TL--------AVTTPAKAQEPVGVQKISV-------SSKARGEDLTVLVWYPAKAG-GEQ-----------VLIG--------DDRI---FQGTPASG-DAVRA--------DGMFPLIVLSHGSG--ASVEKMAWIANELAGDGFIVAGPNHPGTTSG---DS--TPEDTPK-LWQRTDDLATVIDRLLAD-PDWSASIDPEKIGALGFSLGGAAVLESAGATASLEAYADYCD-----TN-P-QMPDCQWFKGGRAFRDREEIRVEPLDLR---------------TVDKTLFEQARQDARITSVVAVDPAL-AA--AFQ-EESLAGIGIPLYFINLGKAG--QIDAGVR----SAHL---A--E--AAPDAELDHIADAVHFSFLPVCKADAMDFMKSIGEPD-RLCTDG-----GGRPRAALHEEMAEMILKAFRTDLKTA---N-------------------------------------------------- =====>
9rhob-a3jra6 ---------------------------------------------------------------------------------M---P--------SL---SNTL-KAT--AVIGTF----VLAGWGI-------------QYATAPAYDGYAGITYSKA-------YAPARDTDVDFTIWYPATPG-GRQ-----------TKAG--------GNGV---FYGTEAGR-GAPHA--------QGEFPMIIISHGAG--GNAGQFGWIASELAQAGYVVVLPNHPGTTSM---NA--SAHAAVR-VWERPADISAVIDQITTN-PQNYPYIDSSRITALGFSAGGYTSMAVAGARVDPDALQHFCD-----EGDH-GMSDCAFLARG------------GVDLH---------------ALDLAPAAQDLRDPRISAAIVIDPGI-VE--TLT-EPSLADIDIPMLILNLGAEN--TIPAGVY----ARPA---A--E--LIPNATYKIFDDAIHFSFLAECKAKGAAILAREGEPD-LLCDDA-----GGRSRHDIHQELKGEITSFLTSINLANMPERRKNDES-------------------------------------------- =====>
9rhob-a4eyc9 -----------------------------------------------------------------------------------------------------MKN-LVLSAA--------L-TCA-A---LV----------QALNAAPYQSGLSDLKI-------ADAGAERPLEGFVWYPTQEV-EGQ-----------EEQH--------SSIV---WEGNMAIP-DATPA--------EGDLPLLVLSHGMY--GNAMNQGWLAAALSRQGYVVATINHPGTSTW---LR--DAEQSRM-LWERPRDISRVIDHFLAP-SAEALRIDPDRIYMAGHSLGGFTAIALAGGRYDAAHSATFCA-----AH-S-SDLACGVFERW------------EIAKT---------------AQDQRAMEADLTDPRIQGFAVFDLGG-TQ--SFA-PASLGLIEKPLLVYGAPRAAAG-LNLETE----ARAL---A--AMAP--NVTYREPSELAHFDFLGVCKPGAEEILAEENPGDEVVCYEG------GDMRRSEQKKIAAEVLTFFESLR--------------------------------------------------------- =====>
9rhob-b6av05 -----------------------------------------------------------------------------------------------------MKR-LIHI------------LCLSL---LI--------GAGQAHAEDQVLGWQKFKV-------KDAQKDRPIEGLVWYPAEND-ARV-----------KRIQ--------SNGV---WVGVDAAK-KATPL--------EGQRPFVVLSHGLY--GNERNQNWLAEALVTKGYIVASLSHPGTSSW---LR--DTGDARQ-LWERPRDVSRVISHLLDD-DTFAPRIDPKNIFMGGHSLGGWTAVWLAGGRYDGDKVKTDCA-----AD-P-SELICKIGDTW------------RIAKT---------------EEDIVSMEQDLSDPRIKAIAVFDLGG-TQ--TFA-PETLSTIKTPLLVIGAPKPSMGSLDLDRE----SRAL---I--ASLPKDNVRYIEPTSLTHFDFLGVCTDRGMDILENEVPGDGELCEGG------TDERIADHALISDAVISFFADP---------------------------------------------------------- =====>
9rhob-b6yyn5 -----------------------------------------------------------------------------------------------------------MKSIILSS----IFA--------L--------TCTSALADMPYAGYDRLTV-------SAPHRTSAVAASIWYPAQTA-TYR-----------GLVG--------DNAV---FKGTSAYV-GAAVK--------DGKHPLILLSHGSG--GNMDTISWLSSGLAQKGAMVLAVNHQGSTSG---DS--SPRRSVR-LDDRAKDLSAALDELLSD-PYLAEHVDKSRITSLGFSLGGATALNLAGLRFDGDRYNEYCQ-----GIGK-SQADCVFLSKG------------GVDFS---------------RM-PAGFSKGVEDPRVSAVVAIDPGF-TY--AVD-EQSLAKVQQPVLLINIGQ-E--HLWKAADVGSNGSNL---V--G--KLEDATYSVVKPGHHFTFLAECKPEGPAILAAEKD-D-PVCDDP-----EGTDRAQIHADIVAEIARFLKL----------------------------------------------------------- =====>
9rhob-b9qx52 --------------------------MEKGLSSLSFITFEDRTQAVRR-LSSGGSSSHLRHSPLLKPG-AVMTSSFPI---S---P--------SR-HLPMMLA-LLALTV--------LPARPAG---AA--------PAETTFSATFGPGVQEFQV-------QDDQTDRPLAGHIWYPTPTP-NHA-----------PRAD--------RSKV---WQMAPADP-GAEVA--------DGTYPLLVVSHGMF--GNTFNQAWLGSELARHGHVVAMVNHPGTSSF---LR--DPLQAQQ-LWERPKDLSRLITHLTER-STWRDFIDQSRVSAAGHSLGGFTVMLAGGARFDGDLYDKGCF-----GDTR-IPVVCDILRGW------------SVAET---------------PEDRRAMEQNLRDSRIRKIISLDLGG-AP--VLS-RSSLSSVAIPVLVLGAGRADM--LDQDLE----SRAL---A--SALPKALTVHIELEDAGHFDFMGVCKPEGFAILQEHEPGDEMVCVKG------GADRELQHQRILNEILMFLEN----------------------------------------------------------- =====>
9rhob-d0d3x3 ----------------------------------------------------------------------------------------------------MKD---V--TKSVG------FAVIFL---FA--------SCAGALAADYIAGVQTLSV-------TSGERATDLEVTIWYPADEG-GTA-----------VTLG--------ENIF---FKGTPAEE-GAPIR--------NGEFPLVLLSHGAGLAGHAGAMGWIAAPLAQEGFIVAAPTHPGNTGR---DR--SAEETMK-LWLRPSDLSKTLDMIEGD-QTFHSHVARDQIGVLGLSMGGNSALSIAGARLDPELFATYCD-----TDDL-NASLCEWVRLS------------GVDLH---------------AMDKGAAGRDNTDPRVRFAVAIDPAP-AD--VFA-PASFADVSVPVFIVNLGKAS--EIPETIQ----ASGI---A--G--AIPGATYQIIEAASHASMFPECKRHAAEIAIEEGIED-PICTDG-----SGSSRDAIHAEIIGLTISAFRNAIGSAD----------------------------------------------------- =====>
9rhob-e2clw2 ---------------------------------------------------------------------------------M---P--------SF---SRRFSSLLLGALCAGS----LFV--------S--------LSAAAQPPQALPGYDRFDV-------QVTHRAWPVQGSIWYPAANR-TYR-----------GMIG--------DNIV---FKGAAVQM-GPRVK--------DGRHPLIVLSHGSG--GNMDGLGWFSSALVEAGYMVLAVNHPGSTSG---DS--SPRRSVR-LGQRVKDLSAALDQVLAD-PYFGQHVDRTRIASLGFSLGGATALQSVGLRFDRVLTKAFCD-----EN-S-DRVGCDFYRKG------------GVDFS---------------KVDPEQFEGDFKDPRFAAPVSVDPGF-TV--GLD-PESLKKVTEPVLLISLGFQN--DNWKAVDVTEEGSGL---A--R--RLPKAEFVRIAPANHFSFLAECKPAGKAILAEEGE-D-PICDDP-----EGGERGLAHQQTINAVLGFLDQL---------------------------------------------------------- =====>
9rhob-q0fmz2 ----------------------------------------------------------------------------------------------------MTS---M--TRLIG------LGGMIV---IA--------SCGQLLAADGLAGIEKRSV-------VSDERETDLDVTIWYPAAEA-GET-----------VTLG--------ENIF---FEGTEARQ-GAPIR--------DGTFPIVLLSHGAGLAGRAEAMSWIAVPLAEDGFIVVAPTHPGNTGR---DR--SAEETMK-LWLRPSDLSQALDAIGKD-PTFHPHVASDRIGVLGLSMGGNSALSTVGARLDPELFAGYCD-----TGES-NPSLCSWVQQS------------GVDLH---------------AMDKSLVGRDNSDPRVRFAMAIDPAP-AD--IFA-LSSLADISVPVSIVNLGPPS--ELPETLR----ASGI---A--K--AMPLADYQVVEDASHASMFAECKPNAAEIALEEGIED-PICTDG-----EGASRAAIHRQLIDMTIAAFRKSLGGEG----------------------------------------------------- =====>
9vibr-a8jy01 ------------------------------------------------------------------------------------------------------MN-WTHLLF-------I--PLLLL---CN-------------SAVAFDVGFTQVTL-------TD-NPNRPLNAAIWYPTSDK------------SDTTLIG--------DNPA---FIGTQVIK-DAQIQ--------SGTFPVILLSHGYR--GNWRNQNWLATKLASRGYIVAAADHPGTTSF---DQ--SPEQAEK-WWERPRDVSRMLDYLLSE-TSWKQSANAENVTAIGHSLGGWTVMQLAGAKIDRATFKSECK-----QY-N-NPRTCGLTEEL------------GLSKV---------------Q-ATEPNNKDLSDPRVQRAVSLDLGL-AR--SFS-VGSLNGITVPTLILAAGIDIG-DLPQALE----SGYI---A--EHMPLSSRRYKVYENATHFSFIQGCKPGAIAMLEEEVPGDGIICKDG-----LGASRGKLHQLILNDIVDFLNR----------------------------------------------------------- =====>
acibl-q1itj5 -------------------------------------------------------------------------MLPRR-------ALLIA-------------------------------LLLVAALSFAKE-K------KKEEPLLRKVGVTLRDFYPPEGYNWRGSDSHSLSVIVWYPAEASA-EE---------KEQYLG------DP--PM---IYAGKAAK-DAIFA------PSFNTYPLVALSHGTG--GSAIQMAWLGTYLAARGYIAVAVNHPGNNAA---TG-YTPQGFAE-GWERAKDISTVIDGMLRD-QRFGTKIDPDRIGAAGFSYGGFTMMELAGATADFKGLLAWCQ-A---PE-NH--NACSPPEMP------------DLIDKFT-----KMQNQPEIKAALDHAGDSYRDPRIRAVFAIAPAI-AR--AFS-KDSLAQINIPVAIVAGEADD--QAPVESN----TKIF---A--AGIK-GAQLTILPNGVGHYTFLDVGTDLA----KKKLP---QLFVDN-----PAVDRQAVHEQVATMAADFFDKELTPVKHKKK------------------------------------------------- =====>
aerhh-a0kpk1 -------------------------------------------------------------------------MTPHG----DSGSVSSQCRLDQ---KGYLMR-LLFRYFLLC-----AICTCSALPSFVV--------------SAEYTGFKRLIV-------TDPVGEKPMDAVYFYPGVAAEKTP-----------STIG------PY--------QI-AAQK-ALNIV------P--GRYPVIVISHGNA--GSLWSHHDLATTLARQGNIVITLTHPGDNYK---DQ-TGAGAISS-WYGRPLQISAVITAATND-VELAKYIDKDKIAFIGFSAGGATGLLLRGGDIDAGRYENYCR-----KY-D-MSAICSN--------------------------------KGVMIND-HPGLVVHPDSRIKAWVFMAPVS-MA--F-A-PGSLRRVIAPTLIFTGDKDE--ELSWKEN----ARDL---A--TTLA-AEKEFQVIHNAGHFVFLSPCSAQL----NKLAP---AICNDA-----PGVNRDDIHTIINGKISEFLSRAWLKVKEPRV------------------------------------------------- =====>
agrrk-b9j8e4 ---------------------------------------------------------------------------------------------------------M----HFTK-----FL----C-----FI------VVCLTATWAHAAGLKSFEV-------PADASGPALRVLIWSPCAVAP-AD-----------ITLG------PI--------VV-SGVR-NCPIV------G--DNLPLVVISHGHA--GSSLGHHDTAETLADAGFVVVALNHPRDNFS---DM-SQSGDISV-FVERPTDIKRLIDFMLNA-SPEAAKIDPSRIGFFGFSRGGYTGLVLAGAIPDFHDPH-VSC-----PE-P-A-PICGQIRR------------------------------NELPTQ-----PLTQDARIKALVIADPFS-FF--ST--KDSLKNVKAPVQLWGSQYGG--DGVLPEN----VIAL---T--GDLP-AKPEFHVVSNAAHFAFLAPCSPAL----TQSLP---EICKDA-----NGFDRVAFHKSFDADVLSFFRRHLIEAGKP--------------------------------------------------- =====>
agrrk-b9jlc3 ------------------------------------------------------------------------------------------------------MT-M----IRLR-----FF----L-----AA------LFCLAAPLAHAAGFQLIEI-------PADGPLPALKGGIWYPCAQPA-GD-----------VTIG------PF--------TM-SVTK-DCPIM------G--ETLPLVVVSHGRI--GSALGHRDTAETLADAGFVVVAISHPGDNSL---DQ-SRTRDFSV-FVERPADIRRVIDFVLGP-WPNAGKIDARRIGMFGFSRGGYTGLVAIGANPHFGKRL-RLC-----DG-N-SSVLCDQVHK------------------------------GELPE-------LAHDPRIKAAVIADPLS-VF--FT--PDSFENVKIPVQLWGSERGG--DGVTPES----VVAI---S--NQLP-TKPEFHAVPNSQHFDFLPPCPAEL----AKSAP---EICADR-----SGFDRTEFHRKFNAEVLAFFRKHLVDVQ----------------------------------------------------- =====>
agrt5-a9cki2 -------------------------------------------------------------------------------------------------------MRTF--TTITTF----LFSALAI---Q-------------PLFAGEAVGVSDIAI-------HSPDRGKDLAVTIWYPSDGK-GTQ-----------VLSG--------EDRI---FQGTPAFK-DAAVQ--------PGRLPLVLLSHGSG--SRVSGMAWIAEKLASEGFIVAGTNHPGTTSG---DS--TPADTPK-IWERTSDLSAIVTALTTQ-GKWSASIDAGRIGVLGFSLGGSAAMEISGARADLEAYARYCE-----KE-A-AMMDCQWFDGGQAYVNNEPVSVPKLDLR---------------TLDKARFEQQNRDPRIRSAVLVDPGL-AL--AFQ-PESLRKIDIPLTFINLGSKG--KIPPAVL----ADRL---A--A--EVPGATYRQVDEADHFSFLPLCKEGASAFLKSVGERD-PICEPT-----GPRDRSDIHAELEKMIVAAFNRTLKPG---Q-------------------------------------------------- =====>
agrt5-q7cx24 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWYPAAS-SGKT-----------ETVG--------ENAA---IYGLEVQP-AAPFL--------AGSHPVVLISHGFG--GSWRNLNWIAGVLVQQGYVVAAPDHNGESFT---EA--NATEIVP-LWERPRDISRTLTALLDR-DDLAGRIDSQRIAVIGHSLGGWTAMELAGARYSADLALKDCN-----TE-K-LPPQCKAPRLL---------GKVGIVGG---------------GKADPRLSMDWRDARIRAVIALDLGP-AA--GFL-PETLEQVKVPVLVLAAGVETPEIAAIKAD----SKYI---A--GYLPKATRVYREIPDASHFSFMQICKPNGEKIVEELSPGEGFVCRNG-----GGRDRAALHAEIADAILGFLKAEMR-------------------------------------------------------- =====>
agrvs-b9jr09 ---------------------------------------------------------------------------------------------------------M----KVGR-----CL----L-----AA------VLILTAGQANSAGLKSFDI-------PADAQGPLLKAVEWSPCAKPD-GE-----------IKAG------PF--------IL-PGVR-DCPVE------G--ENRPLIVISHGFG--GTNLSHHDTAEALADAGFVVVAINHPDDTAA---NK-ERQHNLKA-LISRPVDVKRVIDFMLGS-SPDAARIDPQSIGFFGFSRGGYTGLVLAGANPDFRSLP-SQC-----QD-Q-NAASCDHANQ------------------------------NSLPKQ-----ALQHDPRIKAFVIADPLS-SF--FSA-PSSVQNVTAPIQMWGSQYGG--DGVSPEN----LLTV---A--SNLP-DKPDFHTVPNSEHFAFLTICPAEL----IRNLP---ELCTDR-----QGFDRAAFHQEFNRQVIAFFKAHL--------------------------------------------------------- =====>
alcxx-e5u3t0 ----------------------------------------------------------------------------------------------------MFKP-F----LRA------------C-----FV------LSLLATGAAHAAGFQRLNL-------PMDMNGPALQGGIWYPCAAPA-QD-----------VAIG------RV--------TL-AATP-DCPMT------D--GAKPLIVMSHGSA--GSYLGHHDTAAALADAGFVVAAINHVGDNAV---DR-SRQGYLSI-FSTRPREIRRLLDYLTGA-WPQRARLDG-AIGFFGFSRGGYTGLVLAGAAPDFKLGLGLCA-----DE-P-ALPMCRDIRD------------------------------GKVPAQ-----PYVKDARIKALVIADPLN-AF--SA---EALKAVSIPVQLWASARGG--DGVTPAS----VDAV---R--LGL--AAPEFHPVAGAGHFAFLAPCATAQ----AEAAP---AICRDA-----AGFDRAAWHRDFNAAVVAFFRNALR-------------------------------------------------------- =====>
azos1-d3nrk5 -----------------------------------------------------------------------------------------------------MTR-FPPSALLALAVVALAVLAPAL---PA--------HADQPAAEPPVIGFQKLAL-------PATPEHRALEVAVWYPAEP-VGDS-----------TLVG--------DTPV---MTGMALRA-GAPPR--------PGRHGLVVLSHGYG--GNWTNQQWLAAGLVAQGYVVAAPNHPGSTSR---DM--APPGASM-LWKRPGDISRVIDWLTGE-PRWSGLLIADRAAVIGHSLGGWTAVALAGGRFEPWRHEAACK-----AH-P-AMAACGPEIGAL-------EGGDTNAPT---------------PTSQAWSGAALADRRIAAVVTLDLGL-AQ--GFD-PASLAALDKPFLVLGAGPGN-PKMPVELE----SRHL---A--ALLPRDKARYVEIADASHFSFLGICKTGAIPLLEAASPGDGMICRDGDGTDGDGRNREAIHRQLSELVVGFLTSAMPPRAMPPN------------------------------------------------- =====>
bilwa-e5y7a1 -------------------------------------------------------------------------------------------------------------MTRRF-----LFFLLAFLI--LT---------CTAYAAPLQPGFKTLGI-------WDPAKNVRLDFAVWYPSRSAP-FQ-----------VNYG------DW--------NF-SAAR-GRPPV------E--GKHPLILLSHDSA--GSRFSLHELASELARNGFVVLAFTHPGDNVD---DM-GALFMPVQ-VTDRAKQLTQALDIALAD-PETAPLIDPDRIGVLGVGPGGTAAMLIAGARLDATGWPIYCAGKEE-----NADPYCTPWARQ------------R---MG--------AFSTTPNLS-----APYRDRRVRAAAAVSPSY-AM--MFT-PASLSRIRIPLLLLRAERTP--LY-TLQH----AERL---L--SAMP-QPPQLGVLPDADTASLMSSCGGNL----DQTLP---EMCLAV-----SPSRRKAIQAKMAAESAAFFLKYLGTPNPPPLPPEPED-NPQITSHP-ATP------EKNAARKKKR-------------- =====>
brasb-a5eac3 ---------------------------------------------------------------------------------------MHQPR--R---TPMFAV-I----RACQ-----VF----S-----IL------AVCLTATLTHAAGLRAIDI-------AAASDGPEIHGMVWYPCAEQP-TE-----------IPIGG-----GF--------TL-TGVK-DCPLM------G--GHLPLVVASHGRG--GSLLSNRDTAEALADHGFVVAAINHPGDTAR---DR-SRSGDLSV-FVERPADIKRLIDFMVGP-SPFAADIDRDRIGFFGFSRGGYTGLVLLGADPDWAGAASDYC-----QP-I-RRLFCQEILD------------------------------KRTPSQ-----PLTHDPRIKAAVLADPLA-IF--LS--PASFAPIKTPVQLWASSRGG--DGVLPSH----VAFV---D--ANLP-AAHDYRVVPNSGHFAFF-LCPPAL----VQGQS---ELCVDA-----PGFDRTAFHAEFNAEVLAFFRTWLVPTAK---------------------------------------------------- =====>
brasb-a5eiy7 ---------------------------------------------------------------------------------------MAGAR--R---VKRLQE-T----VVLR-----IF-A-AL-----SF------SLTILSSSANAAGLQLLD------------ADPKLKGAIWTPCAKAD-ES-----------VPLGGLAITGEN--------SL-PGVK-DCPIK------G--TKLPLIVFSHGRG--GWFGQHHDLNEALADAGFIVAAISHPGDSFG---DD-AARESLST-WASRPADIVRLTDFMLND-WNGRTAIDPDRIGFFGFSKGGYTGLVLAGADPDMQRVA-QYC-----TQ-A--NPFCTQVRG------------------------------GDTPTS------WTHDARIKAAVLADTAP-ST--PFT-QPNLAAIKIPLQIWRSELGG--NGADPGG----TARV---A--DALP-GHPEVHTVPA-AHFAFLAPCSAEL----AAAVP---RICANTP----ADFDRAAFHRSFDAEVVRFFVEHLAGR------------------------------------------------------ =====>
brasb-a5eml7 ---------------------------------------------------------------------------------------------------------M----RSTK-----FV----F-----AI------CFLFGLTAAKAAGVRNFDI-------PAGATGPAIRLLVWTPCAESP-QE-----------MDAR------GA--------IF-FAVP-GCPVT------G--EKLPLIVISHGRR--GWFGGHHDTAAALADAGFVVAALNHPGDTWR---DT-SRTDSLSV-LVERPADISRLIDYMLDG-WPDAPRIDAQHIGLYGFSFGGYTGLAVIGGNPDLRKGL-PNC-----AT-S-SLLACKQLES------------------------------GEAPGQ-----LIKPDPRVKAAVIVDPYP-AF--VFP-EKNLKRTTIPVQLWSSDPAQNADGLSGCC----AAAV---K--QGLP--VPDYHFVANARHFSFLATCTLKE----AQANP---AVCTDA-----PGFDRVDFHRNLHADIVAFFRKHFAESANP--------------------------------------------------- =====>
brasb-a5erc8 ----------------------------------------------------------------------------------------------------------------------------------------------------MRVGFRQGHIADASRPNWDGDGPRPIDWFAWYPAPDDA-TE---------AALPVA------PWPEGW---FAAGPAAL-DAPLA-------ADGPYPLVVYSHGTG--CNGLQFEWLARELAAHGFVAVAVNHHGNSNA---AP-YRAEAFLC-SWERPRDISLLIDHIVAH-PAFAGRIDADRLFAVGYSLGGVTATALLGAIMIRSPFEPGA----------N--LGRGPREFP------------DLVDHLP----RLMAESQIFRDSWARMSASCHDPRIKAALLLAPGRSVQ--GFS-EDSVAAINVPTHIMAGGADA--LLPA-------ARWL---Q--ERLG-DSTFDIIADDAGHYVFLPESTELG----RSSDP---ACCVDP-----PSVDRGTIHRTVVAAALKLFSA----------------------------------------------------------- =====>
braso-a4ymj8 ---------------------------------------------------------------------------------------------------------------------------------------------------MMPIGFRHGRFTDAARPNWNGDGPRPIDWFAWYPAKDGT-AE---------TTLPVA------PWPHGW---FKAGPAAL-DGPLA-------ADGLYPLVVYSHGTG--CNGLHFEWLARALAAQGFIAVAVNHHGNSNA---EP-YRAEAFLC-SWERPRDISLLIDDIVAD-PGFASRIDPDRIFAVGYSLGGVTATALLGAIMIRSPFAPGA----------N--LGRGPREFP------------DLVDHLP----RLMEQSPVFRDSWARMSASYHDRRIKAALLLAPGRSVQ--GFS-EESVAAINVPTHIMVGGADA--LLPS-------ARWL---H--ERLP-DSAFDVVADDAGHYVFLPESTELG----RSSDP---ASCVDP-----ASVDRGKVHRTVVAAALKLFTR----------------------------------------------------------- =====>
burch-a0b1h8 ---------------------------------------------------------------------------------------------------------------MKN-----RL----L-----AA------LLCLSATVAHAAGVKFLRI-------PADAAGPELRAMVWTPCADAT-QS-----------LTVG------PY--------TL-KGRR-DCPTA------G--DKLPLVVISHGHG--GSFLGHHDLAETLADAGYVVAAINHPGDTFS---DM-SRAADLQE-FVERPADIKRLVDYMLGH-APDAAHIDPARIGFFGFSRGGYTGLVLAGGNPDFAHAP-VAC-----PD-P-AWPICKQIRA------------------------------GDLPKA-----PLTHDPRIKAYVLADPLD-EF--PT--ADTLKNVRAPIQLWASAEGG--DGVTPDT----APAL---A--ALLP-QRPEFHVVPNSAHFAFLAPCPEQL----AHHAP---DICTDA-----KGFDRTAFHASLDAKALAFFNANLR-------------------------------------------------------- =====>
burgb-c5amd6 ------------------------------------------------------------------------------------------------------MR-W----MVTL-----VLTIICTCS--LL-----------AAPAAFNAGVVRLTV-------A--GEAAPFDAMVFYPTREPE-VP-----------WQAG------PF--------TV-EATR-NAAPA-----PG--GRFPVVLISHGRG--GGPLGHRELARALARAGFIAILPTHVGDASG---YP-RASSQARI-LIDRPRQAEAALNTVLAD-PRFSASADPGRIGMIGYSAGGYTALILAGAKPDFAFASAYCA-----SH-DDPGS-CPRSVSS------------DGANGA--------RSQAAVPAE-LADWQPPVDHRLKALVLMDPLA-VM--F-E-APGLAAVRVPTLLYRPQDDS--YLGAARN----ALAV---V--AGLP-TPPAVHVVPG-NHFVFIDPCPDSV----AAGVA---LICRDA-----PGVDRVEIHRRIDQEVINFLRARL--------------------------------------------------------- =====>
burp6-a3nfg1 ----------------------------------------------------------------------------------------------------MKWP-M-------P-----HI----L-----LI------VLCLLTSVAHAAGSQLLRV-------PPSDGRPALMGMVWYPCADDI-GA-----------SAAG-------A--------AA-RNGA-RCPMR------G--DALPLVVISHGSA--SSFGAHYDTAEALAEHGFVVAAINHPGDTTN---DE-SEIGSLSALLVDRPADMKRLIDFMLTG-WHDAARLDPRRIGFFGFSRGALTGLIVAGGKPELSRMIVECE-----NE-P-TWGVCQNP---------------------------------ILPRR-----PLPRDARIRAMVLADPVF-GA--IF--ANGLAGVTIPVQLWASEYGG--DGMSPSD----VEAV---A--RGLP-EKPAYFVVPRAAHFAFIAPCDRAS----MEAVP---RICNDG-----EGFDRIRFHQAFNARVVGFFEQTLRDPRPAATPGVG-QPRAQNETS------RT--------------------------- =====>
burpp-b2tbr5 -------------------------------------------------------------------------MFRVS-------CAVIA----GLA-------------------------CAAALCCAGA---------ASADQAGLHVGETMRVFHPAVARNWRGAKTEALVTRIWYPVDASV-PQ---------TPHEIG------APGQPI---FHGHAAAD-DAPLS------TARASYPLLVLSHGTG--GTADSLDWLAAAIAAQGYIVAGANHPGNTAA---EP-MTRDGFML-WWERATDASEVLDGVLAD-PLLGPHVDRERIGAVGFSLGGYTVLELAGARTNLQAFERFCT-S---PE-AD--AICHPPEAA------------RIHDASGAALSTLDDLSPQAKASRARSGASYRDPRVKAVFAIAPAL-GE--AFD-SNSFAD</ |
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