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MSA from Cobalt (Ncbi) Cobalt
Color code	Main amino-acide (aa) at this position	Non majority aa at this position	50% conservation	Catalytic site	Catalytic site in alignement
Position       	....5....10...5....20...5....30...5....40...5....50...5....60...5....70...5....80...5....90...5....100..5....110..5....120..5....130..5....140..5....150..5....160..5....170..5....180..5....190..5....200..5....210..5....220..5....230..5....240..5....250..5....260..5....270..5....280..5....290..5....300..5....310..5....320..5....330..5....340..5....350..5....360..5....370..5....380..5....390..5....400..5....410..5....420..5....430..5....440..5....450..5....460..5....470..5....480..5....490..5....500..5....510..5....520..5....530..5....540..5....550..5....560..5....570..5....580..5....590..5....600..5....610..5....
9acar-g3msq0   	--------------------------------------------------------------------------------------------------------------------------------------MNTL----SAFA--RTASRRS-----LVK--LQSTSCSFGFIRCS--------------------------SDLK---P--ASTLNPPGFYVQAL--N-----YRIHVETVGNGPRPVVLLPGAIG----------------------------------------------------------S-TRTDFLPQLEKLDR--KLFTIISWDPPGYGFSRPPE-RNFPVD----FYHRDARVLAKVMQKLGHR-QYSVVGWSDGANTGMILAAI--QPDCVQKLVAFGGNAYITEEDVQLL---EATRNTE-KWSE---RMRASMEALYGAE-HFRHLWSSYCDFYRDLL-----Q--KHRGE-VCSNELPHIHCPTLIIHGGKDPLVPSHHPYYLLQ----HIAKA----KLYVVPDG-----------KHNLHFKYADEFNKIVTEFLIS------------------     =====>
9chlr-e1iig9   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHQTTLPD--G-----ATLAYHDRGTGAA-LLMLHGFTG----------------------------------------------------------T-ARSHLGSLI-DD--LSQHYRVIAPDLRGYGMSRPPL-RDFPPD----FYQRDASDMAALLDRLAPG-PVVVLGFSDGAESALVLAAS--RPDLVRGVVAWGVAGVIAPQMAAAA--QRWL--PVSAWGANRAAWRAEIVATQGEA-MLEPLISGWAAAVAAIL-----AA---GGN-IVYDQADQIRCPVLLINGDGEVNNLPEDVRRLAA----RIPNA----RLTFVTQS-----------GHSIQDDQPEVLLHLIRHFLEQVC----------------     =====>
9firm-c4g9n9   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYIQLK--N-----QVLYYEKSGQGDP-ILLLHGNGG----------------------------------------------------------S-HG-EFDVLT-AD--LELDYTVYAMDSRGQGLSAKP--AEF-------HYQDMADDVVGLIQALEIK-KPAIYGFSDGGIIALLVASQ--HPDLVSSLMISGANLSPRGVSFFVR------Q-------------------HIRRLAKKT------GDPLQTLM-----LT---EPH-ITRADLEKISCPTLVLAGSMD-LILPAETRRIAE----WIPDS----QLMILPRE-----------THSSYVLHSDKLGPILRKFLNPNSF---------------     =====>
9maxi-c1bs44   	----------------------------------------------------------------------------------------------------------------------------------------------------------------MIH--LFSTTLTLGSRFLE--------------------------KVPLTVVRTMSSSNRGKSQLLDID--G-----QRIHVTTYGSGRHPVLLMPGALG----------------------------------------------------------S-GETDMKSLTDNSSR-DMDWTLIAWDPPGYGKSRPPS-RIFPSD----FYVKDAESGVQTMAKLGFD-NFSLAGWSDGGISALIAAAQ--YPSLIKKCLVWGTNAYFTQEDYDMI---NKVRDVS-KWSP---RMREPMENMYGVD-GFPVLWNDWVEAIAQIM-----K--NNGGD-ICKNLLGDIKCPTLIIHGDKDAMVAPEHPNYLEK----NISGS----ILKRFPDG-----------KHNLHLKYKKEFNELMESFFLH------------------     =====>
9maxi-c1bs62   	----------------------------------------------------------------------------------------------------------------------------------------------------------------MIH--LFSTTLTLGSRFLE--------------------------KVPLTVVRTMSSSNRGKSQLLDID--G-----QRIHVTTYGSGRHPVLLMPGALG----------------------------------------------------------S-GETDMKSLTDNSSR-DMDWTLIAWDPPGYGKSRPPS-RIFPSD----FYVKDAESGVQTMTKLGFD-NFSLAGWSDGGISALIAAAQ--YPSLIKKCLVWGTNAYFTQEDYDMI---NKVRDVS-KWSP---RVREPMENMYGVD-GFPVLWNDWVEAIAQIM-----K--NNGGD-ICKNLLGDIKCPTLIIHGDKDAMVAPEHPNYLEK----ILVGP----F----------------------------------------------------------     =====>
9rhiz-g6y654   	-----------------------------------------------------------------------------------------------------------------------------------------MT-RFWKAF--AVLLLLTAS---------TAFALAEERWQTLP--------------------------------EPAAMPKPDQSGYAPVN--G-----IQMYYAVFGAGDP-VLLIHGGLG----------------------------------------------------------H-AD-IWASQV-AT--LSKTHKVIVADSRGHGRSTRTE-QPY-------GYDLMASDYLALLDYLKID-KTALVGWSDGGIIGIDIALH--HPERLTRLFAQAANVTTDGVDPGVM------TNKTFAAYID--RSGR----DYKKMSKTPDQYDAFVAQISHMW-----ET---EPA-WTKEQLGKITTPTAIVAGDHDEAIKREHTEYMAS----AIPGA----KLIILPNA-----------SHFAMLQAPDEYSQAALDFIDAK-----------------     =====>
acepa-h1uu55   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEHLTKRWQTLP--------------------------------ATPAPLASFKGQHAPIN--G-----CSLYYTEGGTGDDVIIMLHGGMA----------------------------------------------------------N-SD-YWGIQA-AY--LAKTHRVILVDSRGHGRSTLGD-KPL-------SYAQMADDIIHLMNHLEIP-NASLVGWSDGGVQSIILASE--HPDRIKRIFAYGPHMSASGLNLACS------GDKVVNAFVK--RATE----DYRELSPTPDKFDVFSKTVWGLWKW---EH---DAE-FTEDRLNAIRCPAWVVDGDRDEMIHRAHLEYLVA----HIPDS----SYMILPET-----------SHFAFLQAPLLFNEALADFLSVKA----------------     =====>
acrec-f4wfr0   	---------------------------------------------------------------------------------------------------------------------MYVCF--------------------------VSALHKIVK---------SG-------S-----------------------------VHTRQLSTTANKAREMEERKVKVN--N-----MEINYAKVGTGDHPVLLLPGALG----------------------------------------------------------S-IWTDFKPQVENLNV--DRLTIVAWDPPGYGKSRPPD-RTFPDD----FYQRDATWAYNLMKTLGYS-KFSLIGWSDGGITSLLLASA--YPDSVYRMVVFGANAYIHPDETKIY---ESIRDIN-KWSE---KMRIPMIQIYGKD-YFQKMWSDWIDAVLRLY-----E--KQNGD-LCKQVLPKIKCPTLIIHGAKDAMVLPEHPTYLKQ----NIANS----KLHIFEKG-----------AHNLHLRYSEEFNNLVTNFLVNRK----------------     =====>
acypi-c4wtq7   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDQRSTVST----ELNSKKINIK--G-----FEINYMKVGNGPHKLLIFPGVLG----------------------------------------------------------V-VRSFGPLTE-NL--NGENYTIYVWDPPGYGLSRPPN-RDFSPG----FLDRDADCAIALMEALGIN-RYSMLGWCNGGCTAMIAASR--AADRVDKLVVWSCNAYVTAKDLELY---KMTRDVH-GWPE---GRRITQFKAYGEK-YVTDTWSGWIDAFQKILD----ED---DGD-VCRDALAKINAPTLILHGAKDDFIPVEHGVYLQE----NIKRS----TLEIFPEG-----------RHIVHMMYPEKFVSIVDNFLSSMQ----------------     =====>
acypi-c4wvd9   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLRSKVSI----EMNSTKIKGN--G-----FEINYFKGGNGPKKLLIFPIALG----------------------------------------------------------L-VSDFASLAE-NL--DGEKYTIYICDPIGNGLNRPLN-RDFSPG----FLYRDADYAIALMETLGID-RYSMLGWCYGGRTAMIAASR--AADRVDKLVVWNCSAYVTAKDLEQY---ETIRDIH-RCSE---AFRLPRFVMYGEK-YVSDTWSRLVDAYRKILD----DD---DGD-VCRGELAKINAPTLILHGAKDVLVPVEHGVYLHE----NIKHS----TLEIFPEG-----------GHTMHMKYPEKFVSIVDNFLSSIQ----------------     =====>
aedae-q16si8   	---------------------------------------------------------------------------------------------------------------------------------------------MQIFG-----VLP------FRVLAKPLAGCVPGAV-----------------------------LT---AAVRYRSTCPPIERTLQIG--K-----HKINFVEAGSGEKGLILLPGALG----------------------------------------------------------T-AWTDFKPQIEQLPALLPSHKIIAWDPPGYGKSCPPE-KEFGLD----FYERDAEAAFGLMEKMGFRGAISVVGWSDGGITGLIMAGR--KPSHVEKLVIWGSNAYITPKEAAIY---ENIRDVS-KWSA---RMREPMEKVYGVD-GFPKVWSAWVDGMLGIY-----K--QRSGD-ICKEVLGQIRAPTFILHGAKDPMIVPEHVPHLQG----SIADT----SLHVFDEG-----------KHNIHLKYAEDFNRLVSDFIKK------------------     =====>
ailme-g1m769   	-----------------------------------------------------------------------------------------------------------------------------CGLLRPAAPLGTL----PVQP--KAQ--V------A--------PLDLQPLSTS--------------------------VGAVWSYYVCTANTSITSGKVAVN--G-----VHLHYQQTGEGEHAVLLLPGMLG----------------------------------------------------------S-GETDFGPQIKNLSK--KLFTVVAWDPRGYGHSRPPD-RDFPVD----FFERDAKDAVDLMKTLKFK-KVSLLGWSDGGITALIAAAK--YPSYISKMVIWGANAYVTDEDEAIY---QGIRDVS-KWSE---KTRKPLETLYGYD-YFAKTCEKWVDGIKQFK-----H--LPDGN-ICRHLLRLVQCPTLIVHGEKDPLVPRFHADFIHE----RVRGS----RLHLMPEG-----------KHNLHLRFANEFNKLAEDFLL-------------------     =====>
ampqe-i1e578   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEEQLREVKVSVN--G-----VELHCNIKGNGPNPLLCIPGATA----------------------------------------------------------P-SHWVLSLQLEYFGRSGSEYTVIAFDPRGYGHSKLAP-RTYSMT-PEHHTKIDARDAHQVMESLGYD-KYLVLGWCDGGITAIYLAAL--FPDAVKGVVLWGSRVRYTEYEVEIT---EAG-------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
ampqe-i1fjj6   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNTISVQVN--G-----ASLYCTIRGNGPHPVLLIPGAAA----------------------------------------------------------P-SHWSFSSQLEHLGRTGSQFTAIAYDPRGYGYSHKAP-RTFSVAVPEHHLKTDARDAHELMISLGYS-KYSVLGWCDGGITAIHIAAL--FPEAVNGIILWGSKGYLDKSDIEKV---ESIRDVR-KFNP---KFKKAFEEVYGSEAALQGLWDKYTDSVSATYYYHAREN---SGE-WCDEEMKKVSCKALIFHGAKDSFTALSHARYINE----CIEDS----ELCIIQEG-----------KHQLPDS--LQINSIIEKFFNEC-----------------     =====>
ampqe-i1flz5   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAL-----LSLSRFISQ-----SISSHLAPLGRYLSTGNHQRISSIDVNVP--N----RGQFNVLKGGSGVHSLIYIPGALG----------------------------------------------------------T-ASTDYQYQLEYFSRPDSSFNIVAFDPLGYGRNRSQR-RQFKTE-PIHFLQQDGIDAYHIMQAVEPGKPFSVLGWSDGGVAALFLSAL--YPSLVNKLVVWGANAFLTKQDIEMF---EKTRDIK-KWSP---GMRDSLQAIYGSD--LPQLWSDWLDSMIHIFN----KH---NGD-LCMKELVKIKAPTLILHGDKDPLVPEVHPVYLND----AISDT----RVHVFPNG-----------KHNIHIKYSQEFNKIVEEFLLQK-----------------     =====>
ampqe-i1g7p6   	-----------------------------------------------------------------------------------------------------------------------------DTTLYKVGE-----------K--IDA-----------------KDLRMGAWFEGVV-----VKITRTNRTSSSSEDASDDIQYHVKYDDVSMEEQLREVKVSVN--G-----VELHCNIKGNGPNPLLCIPGSSA----------------------------------------------------------P-SHWAFSSQFEYFGRSGSEYTVIAFDPRGYGHSKLVP-RTYSIA-PEHHTKIDARDAHQVMKSFGYD-KYFVLGWCDGGLSAIYLAAL--FPDAVKGVVLWGSRVRYTEYEVEIA---EGDVNEF-KYLP---I----VLPVYGSPSALQTVWDEGNDCVRAMYE-HLKDK---NGE-LCTEEMKQVSCPTLVLHGARDKVATLSQAQLIKE----TIPNS----KLIVFDQG-----------AHYLHSTLSEDFNLTVESFLNEH-----------------     =====>
ampqe-i1g7p7   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEQLREVKVSVN--G-----VELHCNIKGNGPNPLLCIPGATA----------------------------------------------------------P-SHWVFSLQLEYFGRSGSEYTVIAFDPRGYGRSKLAP-RTYSMT-PEHHTKIDARDAHQVMKSLGYE-EYFVLGWCGGGLSAIYLAAL--FPDAVKGLVVWGSRVRYTEYEVKIT---EAGRDLM-TWNP---EHRQAFEDVYGCRSAYQAVWDQLIDSIHATYE-HLKDK---NGE-LCTEEMKQVSCPTLVLHGARDKMATLSQAQLINE----SIPNS----KLIVFDQG-----------THFIHKT-SEDFNHTVDSFFKKFI----------------     =====>
ampqe-i1gbn7   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEVEQEQQKCRREIKIPVN--G-----VELYCIISGDGPTPVLFLPGAAT----------------------------------------------------------P-TVLSFPFQLEYFGKSGSGYTVISFDPRGYGYSHEVP-RTFSVA-PEHHTKVDARDAYEIMKYLGYE-KYLVVGWCGGGLTAMYLASL--FPDAVQGMITWGSRIHYSERDLEVS---ESMRDII-KGLSEHPEACKKFIEIYGSENTLQTLWGRFTDSVLETYE-YVKDK---NGM-LCSDELSQIKCPTVILHGENDHMTTLDQAKLVKD----LIPGS----QLVLIEEG-----------AHIMQITTPDKFNSAVDGYLKEMMANKEK-----------     =====>
anoca-h9gpi8   	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAVTSAKVEVN--G-----VHLHYQQTGDGNHVVLLLPGMLG----------------------------------------------------------S-GQTDFGPQLKSMNK--QLFTLVAWDPRGYGKSIPPD-RDFPPD----FFERDAKDAIDLMQALKFK-KFSLLGWSDGGITALIAAAK--YPDLIHKMVVWGANSSITEEDVNLY---NGIRDIS-KWSE---KARKPMEEMYGRE-YLSKTCAAWVDGICQFI-----Y--QPNGS-ICQSVLPHIKCPTLILHGEKDPLVPRAHPEYLHK----HIIGS----QLRFVPEG-----------KHNLHLRFAEEFNKAVEKFLL-------------------     =====>
anoda-e3wuy8   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQM---SSEPRQDHLRIG--S-----HDVHFVEAGQGSRGLILLPGALG----------------------------------------------------------T-AWTDFKPQIEKLPTLLPQHKLIAWDPPGYGKSRPPE-KRFSLD----FFEQDAAAAHELMQKLGFD-RYSIAGWSDGGITGMIQAAN--HPDRVEKLIIWGSNSYISDAETKIY---EGI-------------------------------------------------------------------------------------------------------------------------------------------------------------------     =====>
anoga-AGCG47202	------------------------------------------------------------------------------------------------------------FFYSNPCARLSACFSFACASIIFPTSTSVAVKMMRLLASAVAAQCGLAI--RITKTTSALSSCVQSLV-----------------------------ASAVRSRSMCSSAPGAKERRLQVG--A-----STVHFVEAGDGNRGVILLPGALG----------------------------------------------------------T-AWTDFKPQIEGLPALLPHHRVIAWDPPGYGKSRPPD-KQFTVD----FYERDAAAAGELMQKLGFQ-RYSVVGWSDGGITGLVLAAK--QPERVEKLVVWGSNSYISDTEANIY---EGIRDVS-KWSA---RMREPMEQVYGVE-HFPKLWSAWVDGLLRIH-----H--ERKGD-ICSGSLKHIKAPTLVVHGAKDPMIIPDHVPYLLN----NIKNT----DLHVFPDG-----------KHNIHLRYANEFNAIVAKFLLA------------------     =====>
apime-h9k1r0   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKKININ--G-----VNINYLKIGTGN-PVLLLPGAAG----------------------------------------------------------S-IWTDFKPQIEGLDK--EKFTIVAWDPPGYGKSRPPD-RTYPDD----FFQRDATWACDLMKALGYT-KFSLIGWSDGGITSLMLASM--FPDNVQKMVALAANAYVTPEEKEIY---KKYGIID-NWSE---KMKQPLIKVYGEE-YLRKISFDWLESILRIC-----E--KQNDD-LCKESLKKIKCPSLIVQGNKDPMVLIEHASYLKD----HIVGS----KIKIFEKG-----------AHNLHLRYSEEFNNIVTKFLIE------------------     =====>
ascsu-f1l5n5   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MVNTESSGNNG-VI-----IEESAPINT---------EMSN-ATKDSN-EDCTIHEDTTIIN--D-----LKIGYCIYGHGENRMLFICGGVG----------------------------------------------------------C-YKKDYPDCV-LSAFNPSVYTIVCIDPPGYGTSRPPD-RKQEVN----RCMKDAGFCIKLMEHLHMT-PFSVVGWSEGSRTAIHVANQ--GKQYVKSMILLSAGSRVDYRGAGIF---RGMRNTE-QWLP---DAMEAYLKFYSKE-YVTKQWADLCDVVQQVYD----LL---GGRFPCDYVLPNLKLPVLVLTGGMDRFCADPKYF--TT----VLPNC----KTEVRAHA-----------GHDFYLKYPRWFAEQVTKFFIDSKIHLKD-----------     =====>
attce-h9hh38   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENMNV--NELTIVAWDPPGYGKSRPPD-RTFPND----FYQRDATWAYNLMKTLGYS-KFSLIGWS--------------------------------------------IRDIN-KWSE---KMRTPMIQIYGED-YFQKMWSDWIDAVLRLY-----E--KQNGD-LCKQVLPKIKCPTLIIHGTKDAIVLPEHPTYLKQ----NIANS----KFVSLQI----------------------------------------------------     =====>
bommo-g8fpz6   	---------------------------------------------------------------------------------------------------------------------MLITL--------------------------RNAI----L-------RT---------T-----------------------------NCIKMLHAKCMSTAVPKEEKVKVS--G-----CNINYVKVGKGSHNLICLPGALG----------------------------------------------------------T-IWTDYKPQIEGIDK--NDFTLVAWDPPGYGKSRPPM-KQFDVD----FYEKDADYAFNFMKALNIP-KYSILGWSDGGITGIIHAAK--YPETVQKLVIWGSNSFMLPHELEML---KKIKDIK-LWSK---KMRQPMIDVYGEE-LFAKYWSKWVEGMENLF-----N--KKDGN-ICSELLKDVKCPTLILYGEKDPLVDRVHVSHLHT----HIEGS----R----------------------------------------------------------     =====>
bovin-q2kix6   	----------------------------------------------------------------------------------------------------------------------------------------MA----AALG--SRAAR------RM--------RHLLSALKPG--------------------------IQIPRAGPAAAFGSSVTSAKAAVN--G-----VHLHYLRTGGGEHAVLLLPGMLG----------------------------------------------------------S-GETDFGPQIENLNK--KLFTVVAWDPRGYGHSRPPD-RDFPVD----FFERDAKDAIDLMKTLKFK-KVSLLGWSDGGITALIAAAR--YPSYVSKMVIWGANAYVTEQDTEIY---QGIRDVS-KRSE---KTRKPLEALYGFD-YFARTCEKWVDGIEQFK-----H--LPDGS-ICRDLLPLVQCPTLIVHGEKDPLVPRFHADFLHR----HVRGS----RLHLMPEG-----------KHNLHLRFADEFNRLAEGFLQ-------------------     =====>
brafl-c3ygg6   	------------------------------------------------------------------------------------------------------------------------------------MSTVVF----SRLA---------------------SA-----SNRLK--------------------------LILRHVAKASTSAESIPHQKVEVN--G-----VNINYAKVGTGDHPVLLMPGALG----------------------------------------------------------S-TITDFTPQLEKLDR--QKLTVVGWDPRGYGKSRPPD-RQFDIN----FFHQDAADAAALMQKIGFD-KFSLAGWSDGAITAIILAGT--YPQLVRKMVIWGGNAFVTEEDCGMY---EATRDIS-NWSE---RMRAPMINMYGEE-YFRKTWERWIEGITQFL-----Q--QRNGD-ICKTEASQVTCPTFILHGVKDPIVPGVHPDYLQE----HIKGS----RRYDFPDG-----------KHNIHLRYADEFNRLMEDFLMES-----------------     =====>
braja-BLR7144  	------------------------------------------------------------------------------------------------------------------MTPPL------CHALMSGGRTGRRV-MMFRKL--LTALLVMVS---------INAAHAAPQWLSLP--------------------------------PTPTLPKAAQSGFAPVN--G-----IKVWYAVFGRGEP-VLLLHGGLA----------------------------------------------------------N-AN-YWGHQV-RA--LQRRNQVIVMESRGHGRSSRNQ-EPY-------GYDLMASDVVGLLDHLKIR-KAAIVGWSDGAIIGLDIAMK--HPERVTKLFAFAANSDPSGVADI-A------SSDVFNAYIA--RAGE----EYKRLSPTPTEYKSFVAEITKMW-----ES---QPK-WTASDLAAIKVPTWIVDGDHDEAIKRENTEFMAA----NIPGA----GLLIQPEV-----------SHFSFLQDPEQFNDDVLRFLGRRGERAGAAAK--------     =====>
brasb-a5ees1   	---------------------------------------------------------------------------------------------------------------------------------------------MRAAL--LA-LLLLLP---------TGTLYAEPLWQTLP--------------------------------PTPAPVSGVRSGRAAIN--G-----ISLYYGTIGQGSP-VVLLHGGLS----------------------------------------------------------N-SD-YWGHQV-KA--LARTHRVIIVDSRGHGRSTRDA-RPY-------GYDLMADDVVALLDKLSIR-KADIVGWSDGAILGLDLAIR--HPERVRKVFAFAANTLTSGVQEGVE------KNPVFARFIE--RARG----EYAKLSATPGDYDAFVAQITRMW-----ES---EPN-WTDGQLQSIRATVLVVDGDHDEAIKRAHTEYIAA----TIPNA----GLLILPNT-----------SHFAFLQDPELFNAALLHFLDGE-----------------     =====>
bruma-a8q632   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MTNTKSTKNEC---------------ET---------VLND-RGNEEI-KNNEIAELTIIID--E-----QKIGYCRYGAGKYIMLFICGGVG----------------------------------------------------------C-YAKDFPEKL-LNAFNPDNYTIICIDPPGYGKSRPPE-RQQEVN----RCMKDAPFCIKLMQQLNLT-PFLVLGWSEGSRTAIHVAGL--GKQLVNGAILLAAATRIDQRGARIF---RGMRNIN-QWLP---NATEVYLKHYPKE-FVQKQWADLCDVVQQVYD----LL---GGRFPSDYVLPNLKIPVLVMTGGMDRFCADPKYF--ET----ALTNC----RIEKHSLG-----------GHDFYLKYPRWFADKINDFITDPKNHLFC-----------     =====>
burgb-c5als0   	---------------------------------------------------------------------------------------------------------------------------------MPIHPNPNRP-RLRRLL--LCACAAFAL-----------HAQAEPRWRTLP--------------------------------PTPAPVAGEQHGIAEVN--G-----IHLYYATIGHGRP-VILLHGGLS----------------------------------------------------------N-SD-YFGHQV-KA--LMKHHQVIVVDSRGHGRSSRDA-QPF-------GYDLMTDDVVALMDVLKLR-RADIVGWSDGAIIGIDMAIR--HPDRVGKVVAFAANTKTDGVIPEVE------KNPTFAAFIR--RGGD----EYRRLSPTPQQYDAFVGQISHMW-----AS---QPN-WSDAQLKAITTPVLVMDGDHDEAIRREHTEYIAA----TIPGA----GLQILPDT-----------SHFAMLQDPEAFNFAVEHFLGDR-----------------     =====>
burgs-f2lka6   	---------------------------------------------------------------------------------------------------------------------------------MSLFQNRNWL-HLQRFV--LGAVAAFTL---------AHAQAAEPRWQTLP--------------------------------PTPAPVAGEQHGIAEVN--G-----IRLYYATIGHGSP-VILVHGGLS----------------------------------------------------------N-SD-YFGYQV-KS--LMKHHKVIVLDSRGHGRSSRNE-QPF-------GYDLMTDDVVALMDKLKLP-RADIVGWSDGAIIGIDMAIR--HPDRVGKVVAFAANTKTDGVMPDVE------KNPTFAAFIK--RGGD----EYRRLSPTPKQYDAFVEQISHMW-----AS---QPN-WSDEQLKSIRTPVLVMDGDHDEAIKREHTEYIAA----TIPGA----GLQILPNT-----------SHFAMLQDPEAFNFAVEHFLGDR-----------------     =====>
caebe-g0n4q8   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-TQTDYAESHEQIK--D-----VKIGYCRYGHGPNYILAICGAVG----------------------------------------------------------C-YKKDWPLKV-LSQFPPDQVTIIGIDPPGYGTSRPPE-RKQEVQ----RCMKDSEYCLGLMEVLKLE-PFTVMGWSEGARTTVHVAAK--GKEKVNRMIVLAGATKVNHLGAMAF---KGMRETN-HWLP---AGRQPYLDHYPEE-FLRTQWAALCDVVDQVHT----FC---GGRFPCDLVLPQVKCPTLIMNGGMDRFCGDPNVCYIPV----LKTLA----KVEIHAQG-----------GHDFYQKYPKWFSSKVLDFFKATEKK--------------     =====>
caebr-a8x3t6   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-TQTDYTESHEQIK--D-----TQIGYCRYGHGPNYVLAICGAVG----------------------------------------------------------C-YKKDWPLKL-LSHFPPDQVTIIGIDPPGYGTSRPPD-RKQEVQ----RCQKDSEYCLGLMEALKLE-PFTVMGWSEGARTTVHVAAK--GKEMVNRMIVMAGATKVNHLGAMAF---KGMRETN-HWLP---AGRQPYLDHYPEE-FLRTQWAALCDVVDQVHT----FM---GGRFPSDLALPQVKCPTLIMNGGMDRFCGDPNVCFIPV----LKSLA----KVEVHAQG-----------GHDFYQKYPKWFSSKVLEFFKSTEKK--------------     =====>
caeel-K01A2.5  	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-TQSDYIESSEHIK--D-----TQIGYCKYGHGPNYILAICGAVG----------------------------------------------------------C-YKKDWPLKL-LSHFPPDQVTIVGIDPPGYGTSRPPE-RKQEVQ----RCMKDSEYCLGLMETLKLE-PFTVMGWSEGARTTVHVAAK--GKEKVNRMIVMAGATKVNHLGAMAF---KGMRETN-HWLA---AGRQPYLDHYSPE-TLRTQWAALCDVVDQVHS----FC---GGRFPCDLVLPQVKCPTLVMNGGLDRFCGDPNVCFIPV----LKSLA----KVEIHAQG-----------GHDFYLKYPKWFSGKVLEFLKSTEKK--------------     =====>
caere-e3mdg1   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-TQTDYIESHEQIK--D-----TQIGYCRYGHGPNYILAICGAVG----------------------------------------------------------C-YKKDWPLKV-LSHFPPDLVTIIGIDPPGYGTSRPPE-RKQEVQ----RCMKDSEYCLGLMETLKLE-PFTVMGWSEGARTTVHVAAK--GKEKVNRMIVLAGATKVNHLGAMAF---KGMRETN-HWLP---AGRQPYLDHYPAE-FLRTQWAALCDVVDQVHT----FM---GGRFPCDLVLPQVKCPTLIMNGGMDRFCGDPNVCFIPV----LKSLA----KVEIHAQG-----------NHDFYQKYPKWFSAKVLEFLKTSEQK--------------     =====>
calja-f7ecx5   	----------------------------------------------------------------------------------------------------------------------------------------MM----SVLG--RPGVLRLRL--RL--------RMLLTALKPG--------------------------VLVSQAGPAAAFGTSITSAKVAVN--G-----VHLHYQQTGEGDHAVLLLPGMLG----------------------------------------------------------S-GETDFGPQLKNLNK--KLFTVVALDPRGYGHSKPPD-RDFPVD----FFERDAKDAVDLMKALKFK-KVSLLGWSDGGITALIAAAK--YPSYIRKMVIWGANAYVTDEDSVIY---EGIRDVS-KWSE---RTKKPLEALYGYD-YFARTCEKWVDGISQFK-----H--LPDGN-ICRHLLPQVQCPTLIVHGEKDPLVPRFHADFIHE----HVKGS----RLHLMPEG-----------KHNLHLRFADEFNKLAEDFLQ-------------------     =====>
camfo-e2aqx5.1 	--------------------------------------------------------------------------------------------------------------------------------------------------------MIESR---------GM-------A-----------------------------LSIRQLSTMANKTHEIEERKIKID--G-----TEINYARVGRGNHPILLLPGALG----------------------------------------------------------T-IWTDFKPQIENLNA--NKLTIVAWDPPGYGKSRPPD-RTFPDN----FFQRDASWAHNLMQTLGYS-KFSLIGWSGGGISSLLLAST--YPESISKIIVFGANAYIHPDEIKIY---ENIRDIN-KWSE---RMRTPLIQVYGED-YFRKTWSDWIDAMLRLY-----K--KQNVN-TCRMIESRGMALSIRQLS-----------T---------IANK---------------------------------------------------------------     =====>
camfo-e2aqx5.2 	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRKIEERKIKID--G-----TEINYARVGRGNHPVLLLPGTLG----------------------------------------------------------T-IWTDFKPQIENLNA--DKLTIVAWDPPGYGKSRPPD-RTFPDN----FFQRDASWAHNLMQTLGYS-KFSLIGWSDGGITSLLLAST--YPESISKIIVFGANAYIHPDEIKIY---ESIRDIN-KWSE---RMRTPLIQVYGED-YFRKTWSDWIDAMLRLY-----K--KQNGN-LCQEILSKIKCPTLIIRGGKEAMFFPEHPTYLKQ----NIANS----NVHILEKG-----------GHNLHLRYFEEFNNLVTDFLLEQSKI--------------     =====>
camfo-e2aqx6   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANKTHEIEERKMKID--G-----MEINYARVGRSNHPVLLLPGALG----------------------------------------------------------T-IWTDFKPQIENLNT--DKLTIVAWDPPGNGKSRPPD-KTFPNN----FYQRNASLAHNLMQTLDYS-KFSLLGWCDGGITSLLLAST--YPESILKMIVLGAKAYIHPDEIKIY---EIYRDIN-KWSE---RMRTPMIQVYGED-YFRKTWSDWTDAMLRLY-----K--KQNGN-LCKEVLSKIKCPTLIIHGAKDEVVLPEHSTYLEQ----NIADS----TVYIFEKG-----------GHNPHLKYFEEFNNLVTDFLLCQ-----------------     =====>
canfa-e2rgi0   	----------------------------------------------------------------------------------------------------------------------------------MHTPRPMA----AVLD--RRASRQ------L--------RMILSALKAG--------------------------SRVPRAGPAAAFGSSVTSTKVAVN--G-----VHLHYQQTGEGEHAVLLLPGMLG----------------------------------------------------------S-GKTDFGPQIKNLNK--KLFTVVAWDPRGYGHSRPPD-RDFPMD----FLERDAKDAVDLMKTLNFK-KVSLLGWSDGGITALIAAAK--YPLYINKMVIWGANAYVTDEDEKIY---QGIRDVS-KWSE---KTRKPLETLYGYD-YFAKTCEKWVDGMQQFK-----H--LPDGN-ICRHLLPLVQCPTLIVHGEKDPLVPRPHVDFIHK----HVKGS----RLHLMPEG-----------KHNLHLRFADEFNKLVEDFLQ-------------------     =====>
cavpo-h0uyf1   	--------------------------------------------------------------------------------------------------------------------------------LATEGPGTMA----AAVG--CRV----GS--RL--------RLLSSHLKPS--------------------------IPVPRAGPAAAFGTSVSSGKVAVN--G-----VDLHYQRTGEGEHAVLLLPGMLG----------------------------------------------------------S-GETDFAPQLKSLSK--KLFTVVAWDPRGYGHSRPPD-RDFPLD----FFERDAKDAVDLMKALKFK-RVSLLGWSDGGITALVAAAR--YPSYISKMVIWGANTYVTDEDERIY---LGIRDVS-KWSE---KARKPLEALYGYD-YFAKTCEKWVDGIRQFK-----H--LPDGN-ICRHLLPLVQCPTLIVHGEKDPLVPRFHADFIHK----HVRGS----RLHLMSEG-----------KHNLHLRFADEFNKLAEDFLR-------------------     =====>
chick-f1p4c6   	---------------------------------------------------------------------------------------------------------------------------------RGGSAGTMA----WRSA--VTAV-------LMLQ----PRTALLTTRGPA--------------------------A------SYGT---SITSAKIQVN--G-----VNLHYQQTGEGSHAVLLLPGMLG----------------------------------------------------------S-GQTDFGPQLKSMNK--KLFTIVAWDPRGYGQSIPPS-RDFPPD----FFERDAKDAVDLMQALKFK-KFSLLGWSDGGITALIAAAK--YPALIHKLVVWGANASVTQEDVRIY---NGIRDVS-KWSE---KVKKPLEELYGHK-YFAETCEAWVDGIARFA-----E--KPGGS-ICQQLLPHIQCPTLIIHGEKDPLVPRFHAEYIHE----HIKGS----RLHLMPEG-----------KHNLHLRFAEEFNREVEEFLR-------------------     =====>
chipd-c7ptu6   	MKIIPAFIVCCIALVTSLMANAQDGQPPVFFQSIDVSTYKGASFTIECWMYAERTENNSGTALMALGYNQQTQVSTAIGKLSMEDFKAGEWNRLTVSGKIDK-----------RTQSLF------IGALYSGKA------RF---F--FDDMKLFINKKEVPVKNAGFEDTDLSAWKFINQPSSVKVSVTAQLVHGD-KQALSIDASE-IV-SLDYGNNERTGKYATIN--G-----NRIYYEEYGEGQP-LLLLHGALE----------------------------------------------------------S-IR-HYEKQI-PA--LAQSFRVIAVDTRGHGKSTADT-TRL-------TYELYADDMYKLLNELKLD-SVDVLGWSDGGITGLILAMC--HPEKVKKLAAMGANLYPDTTAL-------------YGWLVD--TIQH----QIKVIEAEHTPSNAFALRVNRCM-----LE---EPH-IDPSTLRTIQCPVLVMAGEHD-VIKEAHTRLIAA----SIPGA----ELVIIKNA-----------SHYAPIEVPDEFNKQVETFLKKP-----------------     =====>
chlad-b8gcj4   	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQHRVTLHD--G-----AEIAYHDLGSGPP-VLLIHGFVG----------------------------------------------------------T-ARTHMGLLI-DD--LSRDHRIIAPDLRGYGASRPPN-RTFPPD----FYQRDATDMAELLDLIQPG-PAVVMGFSDGGESALILAAS--RPDVLRGVVAWGVSGVMSQAMVNAV--QDWL--PATAWVERRPSWRQEIIELHGSE-QFEAIIEGWVHAAQAIA-----AS---GGD-ICFQTASRIRCPALLINGDGERNNLPSDVQRLAA----TIPNC----RLEFVTNS-----------GHAIQEDQPEELIRLIRQFLAQLAL---------------     =====>
cioin-f6u176   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKIFVN--G-----VELFYQKFGTGEHVVLLLCGGLG----------------------------------------------------------F-GNIHYKPQIEGFDL--EKFTLISWDPRGYGQSRPPK-RVFPKD----FYYIDADDAIALMEKLGYE-SYSLLGWSDGAILAAIIGAN--KSEKVRKIVKWGGNAFCTPDMMVVY---QGLHDGS-IWSE---DAFGPLLKYYGKE-YFDCILKAWCASFKTMD-----KDSEGNVN-ICSEYLSDVKAPTLIIHGMKDGLVVKMHADFFLE----KIKDS----KLVVFDEG-----------DHHLHLQFPEKFNRLAQEFLLE------------------     =====>
cioin-f6vac9   	--------------------------------------------------------------------------------------------------------------------------------------------------------MLF-K--QFLQ--STAKTQCWSFLN--------------------------------RGLYINKKSTRTMGSKVMVN--G-----VNLYYEKVGTGEHVVLLVPGALG----------------------------------------------------------S-TKTDFKPQLENLNR--DKFTVIGWDPRGYGQSRPPN-RECKPD----FIFRDAEDAVSLMENLGFE-TYSLLGWSDGANISAVMAAR--WSERVRKLVIWGGNSYFTQQELELY---QSIRDLS-TWSK---SMLNPMVEVYGKE-YFEKTWHAWIDMFTEMA-----GGRKEDTN-LYNEELCKIKADTLIIHGQKDALVPDFHPKHFAK----NIQNS----RLVVWEDG-----------KHNLHLRFADRFNELVQSFLLENTSNL-------------     =====>
cioin-f6xa69   	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKLCVN--G-----VELFYQKHGTGDHVVLLLPGGLG----------------------------------------------------------F-GQLHFTPQIQGFDK--KKFTLISWDPRGYGQSRPPK-RVFPKD----FYYIDADDAIALMEKLGYT-SYSILGWSDGAIVACIIAAK--QPNRIRRIVMWGGNAMCPPEMLQSN---DNSSNSA-CEDP---EYSDPSLDYYGKE-YFTYLTRAWAASFHQMD-----KDSEGNID-LCSKCLPKVTAPTFILHGLKDVSVVKIHADHMHK----NIAGS----RLVLWENG-----------EHSLHLQFPDDFNKIAQQFLLESS----------------     =====>
ciosa-h2yma2   	-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGKVLVN--G-----ANLYYEKVGCGDHVLLLVPGALG----------------------------------------------------------C-TKTDFKPQLENLNR--DKFTVIGWDPRGYGQSRPPN-REFHND----FLFRDADDAVQLMEKLGFK-RYSLLGWSDGANISAIVAAR--WNERVDKLVVWGGNAYFTHQELVMY---QSIRDVS-KWSS---TMLKPMVDVYGRE-YFEETWHNWIDMFTTMA-----GDSKSDTN-LYMEELNKIQAKTLIIHGQKDAMVPEFQAKYLNK----HIKNS----RFYFQLME-----------NTTYTLRYSDRFNQLVDQFLT-------------------     =====>
closi-g7yk59   	-----------------------------------------------------------------------------------------------------------------------------------------------------------MR-----INHRLLFGTLLRRERTG-------IEDIRSI-----------------------GKMYHCGLFEAVQ--G-----YKIHYMRAGSGAHNLLLFPGPMG----------------------------------------------------------S-VVTDYSLFLDRL--DKKTFTAVGWDPPGQGGSIPPT-ERSWLQ-QPGRLQEDAHLALGLMRQLNLV-PFSLLGWAEGAITALITVAN-CEPNEFRKLVLWAHEGAIPCVQANLI---DQTQDPR-AWPL---TCRAPLEAMYDSN-YLAENWTHYTWAKNVGYFWHELSDPLIKGR--LTEQFSTNSGPLLLLMRAPGRLNTEDWLTYLLA----QMDNV----RIINWMNQENDIKSIEKYACWGPHRADPDEFQAITEHFLRCGQVKETSEKL--------     =====>
crigr-g3ieg5   	----------------------------------------------------------------------------------------------------------------------------------------MA----PA------AAHPAAL--RL--------RLLLSPLRSR--------------------------IPAPQTKPAAAFGTAVTSAKVAVN--G-----VHLHYQRTGEGEHAVLLLPGMLG----------------------------------------------------------S-GSTDFAPQLQSLNK--KRFTVVAWDPRGYGQSRPPD-RDFPQD----FFERDAKDAVDLMKVLQFK-QVSLLGWSDGGITALIAAAK--YPSYIHKMVIWGANAYVTEEDSRIY---QGIRDVS-KWSE---KARKPLEALYGYD-YFAKTCEKWVDGINQFK-----H--LPDGN-ICRHLLPLVQCPTLIVHGEKDPLVPRFHADFLHK----HVKGS----RLHLMPEG-----------KHNLHLRFANEFNKLAEDFLQ-------------------     =====>
culqu-b0w3i6   	---------------------------------------------------------------------------------------------------------------------------------------------MQLLK-----LC--------SSASKLLTGATTGRA-----------------------------LI----ARTLASNPAPMERLLQVG--Q-----QRINIVEAGTGDRGVLLMPGALG----------------------------------------------------------S-AWTDFKPQIEQLPALLSNHRIVAWDPPGYGKSRPPN-KTFGLD----FYEKDAEAAAQLMEAVGLK-RFSVLGWSDGGITGLVLAGT--KPDVVEKLVIWGANAYITKPEAEIY---EGIRDVS-KWSA---RMREPMEKVYGKE-GFPQIWSAWVDGMLNLY-----R--KRDGD-ICKGVLANIRAPTFIVHGAKDPMIVPEHVPYLKE----AVKST---ELVHVFPDG-----------KHNIHLKYAEEFNKLVSDFLRK------------------     =====>
danpl-g6di47   	-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTLNIP-KFSLLGFSDGGITSLILAAK--YPEAVSKLVVWGANSFILPQELEAY---KKIRDVT-NWSQ---RQREAMNAIYGEE-KFARYWAAWVDAMERIY-----N--TRNGD-ICSEYVKDIICPTYILYGEKDPLVDHVHVSHLHT----TITGS----RIHLYPEG-----------KHNIHIRYAEDFNKRVQEFLLLP-----------------     =====>
danre-Q7ZVE1   	--------------------------------------------------------------------------------------------------------------------------------IDPPSRQNHF----SSVL------RSVSA--VFPA---QMATLMFINR-----------------------------ILRKAATQKR-LYSVSVCGKLSVN--G-----VNLHYQRAGEGKHTVLLLPGALG----------------------------------------------------------S-GETDFGPQLSALDS--SRFTVVSWDPRGYGRSRPPD-RDFPLH----FFHRDAKDAVDLMQALGFR-RFSLLGWSDGGITALIAAAL--NPTLVNKLVVWGANAFVSEEDIQIY---QSLRDVS-LWSE---RMRRPMEQMYGAQ-YFKQTWERWVDGISQFI-----N--KPQGS-ICVDLLPQISCPTLILHGAQDPVVPAYHPQLLQD----SISGS----RLHVFPKG-----------KHNIHLRYSAEFNTLVEQFLNE------------------     =====>
danre-h9gyq0   	--------------------------------------------------------------------------------------------------------------------------------IDPPSRQNHF----SSVL------RSLSA--VF-A---QMATLMFINR-----------------------------ILRKAATQKR-SYSVSVCGKLSVN--G-----VNLHYQRAGEGKHTVLLLPGALG----------------------------------------------------------S-GETDFGPQLSALDS--SRFTVVSWDPRGYGRSRPPD-RDFPLH----FFHRDAKDAVDLMQALGFR-RFSLLGWSDGGITALIAAAL--NPTLVNKLVVWGANAFVSEEDIQIY---QSLRDVS-LWSE---RMRRPMEQMYGAQ-YFKQTWERWVDGISQFI-----N--KPQGS-ICVDLLPQISCPTLILHGAQDPVVPAYHPQLLQD----SISGS----RLHVFPKG-----------KHNIHLRYSAEFNTLVEQFLNE------------------     =====>
droan-b3mtj5   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTNL-----------------------------GRR--LRSPFLNRMLHTERKVRVN--G-----ADLNIVESGSGNRSLLLMPGALG----------------------------------------------------------S-AWTDFKPQIEQLPKLLPEYTIIAWDPPGYGKSVPPK-RQFGLE----FFREDAKAAVDLMRALDRP-KFSILGWSDGGITALIVAGR--YAEAVDRLAIWGAGAYLNADEVKAL---RNIRDVS-KWSP---RMREPMEKVYGVD-RFAQLWGEWVDAACAFY-----D--QRDGD-FCRNEVEQVKAPTFILHGKKDPMIAAEHIPWLKE----RLPKA----KYHEFPEG-----------KHNIHLRYAEDFNKLVADFFNKNDSN--------------     =====>
droer-b3p7h9   	---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGNL-----------------------------CRLVATRSAITWRLVHTERKVRVN--G-----SDLNIVESGSGERSLLLMPGALG----------------------------------------------------------S-AWTDFRPQIEQLPKLLPGHTIIAWDPPGYGKSVPPQ-RKFGLE----FFREDAQAAVDLMRALDRP-RFSILGWSDGGITALIIAGR--HEKAVDRLAIWGAGAYLNADEVKAL---KNIRDVA-KWSA---RMR