11a-quinoxaline
General
Type : Multitarget,Histamine-Receptor3-H3-Antagonist,Quinoxaline
Chemical_Nomenclature : N-(3-aminoquinoxalin-2-yl)-4-(piperidin-1-ylmethyl)benzamide
Canonical SMILES : C1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=NC4=CC=CC=C4N=C3N
InChI : InChI=1S\/C21H23N5O\/c22-19-20(24-18-7-3-2-6-17(18)23-19)25-21(27)16-10-8-15(9-11-16)14-26-12-4-1-5-13-26\/h2-3,6-11H,1,4-5,12-14H2,(H2,22,23)(H,24,25,27)
InChIKey : SXTDBNDGQWAIKW-UHFFFAOYSA-N
Other name(s) : CHEMBL1929400,BDBM50359376,CHEMBL1929401
MW : 361.4
Formula : C21H23N5O
CAS_number :
PubChem : 54765288
UniChem : SXTDBNDGQWAIKW-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : 11a-quinoxaline ligand of proteins in family: ACHE || BCHE || Cholinesterase
Stucture :
Protein :
References (1)
| Title : Searching for the Multi-Target-Directed Ligands against Alzheimer's disease: discovery of quinoxaline-based hybrid compounds with AChE, H(3)R and BACE 1 inhibitory activities - Huang_2011_Bioorg.Med.Chem_19_7158 |
| Author(s) : Huang W , Tang L , Shi Y , Huang S , Xu L , Sheng R , Wu P , Li J , Zhou N , Hu Y |
| Ref : Bioorganic & Medicinal Chemistry , 19 :7158 , 2011 |
| Abstract : Huang_2011_Bioorg.Med.Chem_19_7158 |
| ESTHER : Huang_2011_Bioorg.Med.Chem_19_7158 |
| PubMedSearch : Huang_2011_Bioorg.Med.Chem_19_7158 |
| PubMedID: 22019465 |