217-AO
Tertiary analogue of Echothiophate
General
Type : Organophosphate,Sulfur Compound,Organothiophosphate
Chemical_Nomenclature : 2-diethoxyphosphorylsulfanyl-N,N-dimethylethanamine
Canonical SMILES : CCOP(=O)(OCC)SCCN(C)C
InChI : InChI=1S\/C8H20NO3PS\/c1-5-11-13(10,12-6-2)14-8-7-9(3)4\/h5-8H2,1-4H3
InChIKey : GRPHSFSJUDRMKP-UHFFFAOYSA-N || PXPPTYPWWLDKPW-UHFFFAOYSA-N
Other name(s) : O,O'-diethyl S-ethyldimethylaminephosphorothiolate acidoxalate,(2-mercaptoethyl)dimethylamine acidoxalate O,O'-diethylphosphorothioate,217AO,CHEMBL3277096,BRN 1780326,S-[2-(dimethylamino)ethyl] o,o-diethyl phosphorothioate,S-(2-(N,N-Dimethylamino)ethyl)O,O-diethyl phosphorothiolate,Diethoxy-(2-dimethylaminoethylthio)phosphine oxide oxalate,Phosphorothioic acid, O,O-diethyl-S-(2-(dimethylamino)ethyl)ester, oxalate,Phosphorothioic acid, O,O-diethyl ester, S-ester with 2-dimethylaminoethanol, oxalate
MW : 241.28
Formula : C8H20NO3PS
CAS_number : 3147-20-4 || 470-94-0
UniChem : GRPHSFSJUDRMKP-UHFFFAOYSA-N || PXPPTYPWWLDKPW-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (3)
| Title : On the origin and fate of external acetylcholinesterase in peripheral nerve - Brimijoin_1978_J.Physiol_285_143 |
| Author(s) : Brimijoin S , Skau KA , Wiermaa MJ |
| Ref : The Journal of Physiology , 285 :143 , 1978 |
| Abstract : Brimijoin_1978_J.Physiol_285_143 |
| ESTHER : Brimijoin_1978_J.Physiol_285_143 |
| PubMedSearch : Brimijoin_1978_J.Physiol_285_143 |
| PubMedID: 84869 |
| Title : Sodium transport by the acetylcholine receptor of cultured muscle cells - Catterall_1975_J.Biol.Chem_250_1776 |
| Author(s) : Catterall WA |
| Ref : Journal of Biological Chemistry , 250 :1776 , 1975 |
| Abstract : Catterall_1975_J.Biol.Chem_250_1776 |
| ESTHER : Catterall_1975_J.Biol.Chem_250_1776 |
| PubMedSearch : Catterall_1975_J.Biol.Chem_250_1776 |
| PubMedID: 1167546 |
| Title : Differential effects of quaternary cholinesterase inhibitor, phospholine, and its tertiary analogue, compound 217-AO, on central control of respiration and on neuromuscular transmission. The antagonism by 217-AO of the respiratory arrest caused by morphine - |
| Author(s) : Schaumann W , Job C |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 123 :114 , 1958 |
| PubMedID: 13550065 |