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Inhibitor Report for: 8IV-7Q1N

General
Type Carboxamide, Diphenylacetamide
Chemical_Nomenclature N-[(2R)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-2,2-diphenylacetamide
Canonical SMILES c1ccc(cc1)C(c2ccccc2)C(=O)NC[C@@H](CNCC3CCCCC3)O
InChI InChI=1S/C24H32N2O2/c27-22(17-25-16-19-10-4-1-5-11-19)18-26-24(28)23(20-12-6-2-7-13-20)21-14-8-3-9-15-21/h2-3,6-9,12-15,19,22-23,25,27H,1,4-5,10-11,16-18H2,(H,26,28)/t22-/m1/s1
InChIKey FUOOCCYGXAKPCY-JOCHJYFZSA-N
Other name(s) ~{N}-[(2~{R})-3-(cyclohexylmethylamino)-2-oxidanyl-propyl]-2,2-diphenyl-ethanamide ; (R)-28
________________________________________________________________________________________________
MW|380.52
Formula|C24H32N2O2
CAS_number|
PubChem|165430606
UniChem|FUOOCCYGXAKPCY-JOCHJYFZSA-N
IUPHAR|
Wikipedia|

Target
Families | 8IV-7Q1N ligand of proteins in family: BCHE
Stucture | 1 structure: 7Q1N: Crystal structure of human butyrylcholinesterase in complex with N-[(2R)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-2,2-diphenylacetamide
Protein | human-BCHE

References:
Search PubMed for references concerning: 8IV-7Q1N
    Title: Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies
    Panek D, Pasieka A, Latacz G, Zareba P, Szczech M, Godyn J, Chantegreil F, Nachon F, Brazzolotto X and Malawska B <7 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 249:115135, 2023 : PubMed