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Inhibitor Report for: Bis-Noreseroline

leaving group of Bisnorcymserine. Product of hydrolysis


General
Type Leaving group, Indole, Derivative of physostigmine-eserine
Chemical_Nomenclature (3aR,8bS)-8b-methyl-2,3,3a,4-tetrahydro-1H-pyrrolo[2,3-b]indol-7-ol
Canonical SMILES CC12CCNC1NC3=C2C=C(C=C3)O
InChI InChI=1S/C11H14N2O/c1-11-4-5-12-10(11)13-9-3-2-7(14)6-8(9)11/h2-3,6,10,12-14H,4-5H2,1H3/t10-,11+/m1/s1
InChIKey BLEHTFVVORLVPX-MNOVXSKESA-N
Other name(s) NHG
________________________________________________________________________________________________
MW|190.24
Formula|C11H14N2O
CAS_number|
PubChem|56965941
UniChem|BLEHTFVVORLVPX-MNOVXSKESA-N
IUPHAR|
Wikipedia|

Target
Families | Bis-Noreseroline ligand of proteins in family: ACHE
Stucture | 1 structure: 3ZV7: Torpedo californica Acetylcholinesterase Inhibition by Bisnorcymserine. Crystal Structure of the Complex with its Leaving Group
Protein | torca-ACHE

References:
Search PubMed for references concerning: Bis-Noreseroline
    Title: Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group
    Bartolucci C, Stojan J, Yu QS, Greig NH, Lamba D
    Ref: Biochemical Journal, 444:269, 2012 : PubMed