Dimethylhydroxycarbaphen
General
Type : Muscarinic antagonist,Propionate,Carbamate,Pro-Drug,Multitarget,Not A\/B H target
Chemical_Nomenclature : 2-(diethylamino)ethyl 2-[4-(dimethylcarbamoyloxy)phenyl]-2-(4-hydroxyphenyl)propanoate
Canonical SMILES : CCN(CC)CCOC(=O)C(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OC(=O)N(C)C
InChI : InChI=1S\/C24H32N2O5\/c1-6-26(7-2)16-17-30-22(28)24(3,18-8-12-20(27)13-9-18)19-10-14-21(15-11-19)31-23(29)25(4)5\/h8-15,27H,6-7,16-17H2,1-5H3
InChIKey : WSSHBIZVZFEFDX-UHFFFAOYSA-N
Other name(s) : CHEMBL288482,BDBM50018226,2-(4-Dimethylcarbamoyloxy-phenyl)-2-(4-hydroxy-phenyl)-propionic acid 2-diethylamino-ethyl ester
MW : 428.5
Formula : C24H32N2O5
CAS_number :
PubChem : 14537192
UniChem : WSSHBIZVZFEFDX-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : Dimethylhydroxycarbaphen ligand of proteins in family: BCHE
Stucture :
Protein : human-BCHE
References (1)
| Title : Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates - Leader_1989_J.Med.Chem_32_1522 |
| Author(s) : Leader H , Smejkal RM , Payne CS , Padilla FN , Doctor BP , Gordon RK , Chiang PK |
| Ref : Journal of Medicinal Chemistry , 32 :1522 , 1989 |
| Abstract : Leader_1989_J.Med.Chem_32_1522 |
| ESTHER : Leader_1989_J.Med.Chem_32_1522 |
| PubMedSearch : Leader_1989_J.Med.Chem_32_1522 |
| PubMedID: 2738887 |